Page last updated: 2024-10-23

biperiden and Basal Ganglia Diseases

biperiden has been researched along with Basal Ganglia Diseases in 32 studies

Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
biperiden : A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
" Efficacy of ziprasidone (80-160 mg/d) and olanzapine 10-20 mg was measured using the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impression (CGI) Scale, the Calgary Depression Scale for Schizophrenia (CDSS), and the Heinrich Quality of Life Scale (HQLS); tolerability assessments included laboratory assessments, body weight, and electroencephalogram."9.15Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial. ( Buitelaar, JK; Grootens, KP; Kahn, RS; Peuskens, J; Sabbe, BG; Thys, E; van Veelen, NM; Verkes, RJ, 2011)
" Efficacy of ziprasidone (80-160 mg/d) and olanzapine 10-20 mg was measured using the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impression (CGI) Scale, the Calgary Depression Scale for Schizophrenia (CDSS), and the Heinrich Quality of Life Scale (HQLS); tolerability assessments included laboratory assessments, body weight, and electroencephalogram."5.15Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial. ( Buitelaar, JK; Grootens, KP; Kahn, RS; Peuskens, J; Sabbe, BG; Thys, E; van Veelen, NM; Verkes, RJ, 2011)
"A 52-year-old woman developed severe hyponatremia following treatment for hypertension with chlorthalidone."3.68Extrapyramidal syndrome responsive to dopaminergic treatment following recovery from central pontine myelinolysis. ( Goldhammer, Y; Sadeh, M, 1993)
"The pseudosclerotic type of Wilson's disease, also known as the Westphal-Strümpell form, is distinguished by positional tremor, ataxia and dysarthria as the main symptoms."1.30[Schizophrenia-like symptoms in the Westphal-Strümpell variation of Wilson disease]. ( Landgraf, F; Müller, J; Trabert, W, 1998)
"Two weeks after epidemic parotitis a 10-year old boy developed an acute extrapyramidal syndrome together with pyramidal tract signs but without impairment of consciousness."1.26[Encephalitis of the basel ganglia associated with mumps]. ( Heuser, L; Kellermann, K; Mertens, T, 1982)
"Biperiden hydrochloride has been used in the treatment of Parkinson's disease and related disorders within two drugs: --Akinophyl, --and Akineton which is chemically similar but has a slower effect."1.26[Treatment of the neuroleptic syndrome by biperiden hydrochloride under its delayed-action form. A 9-month study on 55 hospitalized patients]. ( Verdeau-Pailles, J, 1976)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199019 (59.38)18.7374
1990's9 (28.13)18.2507
2000's1 (3.13)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Niederhofer, H1
Ota, T1
Miura, I1
Kanno-Nozaki, K1
Hoshino, H1
Horikoshi, S1
Fujimori, H1
Kanno, T1
Mashiko, H1
Yabe, H1
Grootens, KP1
van Veelen, NM1
Peuskens, J1
Sabbe, BG1
Thys, E1
Buitelaar, JK1
Verkes, RJ1
Kahn, RS1
OPPENHEIMER, H1
Baumann, CR1
Jenni, R1
Jung, HH1
Fuhrmann, M1
Hruby, K1
Gössinger, H1
Shroff, D1
Gassner, B1
Shen, WW1
Wässer, S1
Kellermann, K1
Heuser, L1
Mertens, T1
Sadeh, M1
Goldhammer, Y1
Silver, H1
Geraisy, N1
Diltoer, MW1
Rosseneu, S1
Ramet, J1
De Wolf, D1
Spapen, HD1
De Turck, BJ1
Huyghens, LP1
Higuchi, H1
Shimizu, T1
Hishikawa, Y1
Meszaros, K1
Lenzinger, E1
Hornik, K1
Schönbeck, G1
Hatzinger, R1
Langer, G1
Sieghart, W1
Aschauer, HN1
Müller, J1
Landgraf, F1
Trabert, W1
Dose, M1
Hellweg, R1
Yassouridis, A1
Theison, M1
Emrich, HM1
Posada, IJ1
López-Valdés, E1
Vallejo, AR1
Portera, A1
Huffmann, G1
Sinaniotis, CA1
Spyrides, P1
Vlachos, P1
Papadatos, C1
Jellinek, T1
Verdeau-Pailles, J1
Van Putten, T2
Mutalipassi, LR2
Staudt, F1
Linder, M1
Dilsaver, SC1
Kline, NS1
Mason, BT1
Winick, L1
Klett, CJ1
Caffey, E1
Simpson, GM1
Beckles, D1
Isalski, Z1
Lee, JH1
Malkin, MD1
Ayd, FJ1
Haase, HJ1
Floru, L1
Ulrich, F1
Kammerer, T1
Schweitzer-Bucher, E1
Jamet, P1
Royer, M1
Delteil, P1
Decreton, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-Blind, Randomized Trial Of Ziprasidone (80 - 160 Mg) Versus Olanzapine (10 - 20 Mg) In Patients With Recent-Onset Schizophrenia, Schizoaffective And Schizophreniform Disorder.[NCT00145444]Phase 3100 participants Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for biperiden and Basal Ganglia Diseases

ArticleYear
Side effects of depot fluphenazines.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Agranulocytosis; Barbiturates; Basal Ganglia Diseases; Benztropine; Biperiden; Delayed-Action Prepar

1974

Trials

10 trials available for biperiden and Basal Ganglia Diseases

ArticleYear
Effects of Shakuyaku-Kanzo-to on Extrapyramidal Symptoms During Antipsychotic Treatment: A Randomized, Open-Label Study.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases;

2015
Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial.
    Schizophrenia bulletin, 2011, Volume: 37, Issue:2

    Topics: Adult; Alanine Transaminase; Antipsychotic Agents; Aspartate Aminotransferases; Basal Ganglia Diseas

2011
No difference in the effect of biperiden and amantadine on negative symptoms in medicated chronic schizophrenic patients.
    Biological psychiatry, 1995, Sep-15, Volume: 38, Issue:6

    Topics: Adult; Amantadine; Basal Ganglia Diseases; Biperiden; Chronic Disease; Cross-Over Studies; Dopamine

1995
Biperiden and haloperidol plasma levels and extrapyramidal side effects in schizophrenic patients.
    Neuropsychobiology, 1997, Volume: 36, Issue:2

    Topics: Adult; Aged; Anti-Dyskinesia Agents; Antipsychotic Agents; Basal Ganglia Diseases; Biperiden; Chroni

1997
Combined treatment of schizophrenic psychoses with haloperidol and valproate.
    Pharmacopsychiatry, 1998, Volume: 31, Issue:4

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Biperiden; Brief Psychiatric Rating Scale; Chlo

1998
Biperiden (Akineton): effective prophylactic and therapeutic anti-parkinsonian agent.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Biperid

1974
Evaluating the long-term need for antiparkinson drugs by chronic schizophrenics.
    Archives of general psychiatry, 1972, Volume: 26, Issue:4

    Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Biperiden; Chronic Dis

1972
Some methodological considerations in the evaluation of drug-induced extrapyramidal disorders: a study of Ex10-029, a new morphanthridine derivative.
    The Journal of clinical pharmacology and new drugs, 1972, Volume: 12, Issue:4

    Topics: Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Chronic Disease; Clinical Trials as

1972
Phenothiazine-induced decompensation.
    Archives of general psychiatry, 1974, Volume: 30, Issue:1

    Topics: Adult; Affective Symptoms; Basal Ganglia Diseases; Biperiden; Clinical Trials as Topic; Dose-Respons

1974
[Clinical-neuroleptic investigation of N-((1-ethyl-pyrrolidine-2-yl)-methyl)-2-methoxy-5-sulfamyl-benzamide-neuroleptic sulpiride (Dogmatil) in acutly ill schizophrenics].
    International pharmacopsychiatry, 1974, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Basal Ganglia Diseases; Biperiden; Blood Pressure; Clinical Trials as Topic

1974

Other Studies

21 other studies available for biperiden and Basal Ganglia Diseases

ArticleYear
Tizanidine is not effective treating EPMS.
    Medical hypotheses, 2018, Volume: 116

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Biperiden; Cholinergic Antagonists; Clonidine; Clopenthix

2018
[On the treatment of drug-induced extrapyramidal syndromes with akineton].
    Munchener medizinische Wochenschrift (1950), 1961, Jul-28, Volume: 103

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Biperiden; Disease; Extrapyramidal Tracts; Parasympath

1961
Severe extrapyramidal syndrome after exposition to isoamyl acetate vapour.
    Journal of neurology, 2008, Volume: 255, Issue:5

    Topics: Acetylcholine; Adult; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Biperiden; Brain; G

2008
[Clinical aspects and therapy of acute poisoning by the drug combination melitracen-flupenthixol (Deanxit)].
    Wiener medizinische Wochenschrift (1946), 1983, Jun-15, Volume: 133, Issue:11

    Topics: Adolescent; Adult; Anthracenes; Basal Ganglia Diseases; Biperiden; Cardiac Complexes, Premature; Chi

1983
Extrapyramidal symptoms associated with alcohol withdrawal.
    Biological psychiatry, 1984, Volume: 19, Issue:7

    Topics: Aged; Alcoholism; Basal Ganglia Diseases; Biperiden; Dystonia; Female; Humans; Male; Middle Aged; Pa

1984
[Making a diagnosis. Side effects of metoclopramide].
    Kinderarztliche Praxis, 1982, Volume: 50, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Basal Ganglia Diseases; Biperiden; Child; Humans; Mal

1982
[Encephalitis of the basel ganglia associated with mumps].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1982, Volume: 130, Issue:8

    Topics: Basal Ganglia Diseases; Biperiden; Child; Electroencephalography; Encephalitis; Humans; Lymphocytosi

1982
Extrapyramidal syndrome responsive to dopaminergic treatment following recovery from central pontine myelinolysis.
    European neurology, 1993, Volume: 33, Issue:1

    Topics: Basal Ganglia Diseases; Biperiden; Carbidopa; Chlorthalidone; Coma; Drug Therapy, Combination; Femal

1993
Anticholinergic treatment for choreoathetosis in a child after induction with propofol.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Anesthetics, Intravenous; Athetosis; Basal Ganglia Diseases; Biperiden; Child; Cholinergic Antagonis

1996
Recurrent paroxysmal episodes characterized by perceptual alteration in three schizophrenic patients on neuroleptic medication.
    Psychiatry and clinical neurosciences, 1997, Volume: 51, Issue:3

    Topics: Adult; Affect; Antipsychotic Agents; Anxiety; Auditory Perception; Basal Ganglia Diseases; Biperiden

1997
[Schizophrenia-like symptoms in the Westphal-Strümpell variation of Wilson disease].
    Der Nervenarzt, 1998, Volume: 69, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Biperiden

1998
Extrapyramidal side effects and serotonin syndrome with fluoxetine and biperiden.
    Neurologia (Barcelona, Spain), 1998, Volume: 13, Issue:8

    Topics: Aged; Basal Ganglia Diseases; Biperiden; Depression; Fluoxetine; Humans; Male; Parasympatholytics; S

1998
[Akineton delir and other emergencies caused by psychopharmaca].
    Deutsche medizinische Wochenschrift (1946), 1978, May-26, Volume: 103, Issue:21

    Topics: Adult; Age Factors; Alcohol Withdrawal Delirium; Basal Ganglia Diseases; Biperiden; Diagnosis, Diffe

1978
Acute haloperidol poisoning in children.
    The Journal of pediatrics, 1978, Volume: 93, Issue:6

    Topics: Acute Disease; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Child; Child, Preschool; Dys

1978
Mood elevating effect of trihexyphenidyl and biperiden in individuals taking antipsychotic medication.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Emotions; Euphoria; Fema

1977
[Treatment of the neuroleptic syndrome by biperiden hydrochloride under its delayed-action form. A 9-month study on 55 hospitalized patients].
    L'Encephale, 1976, Volume: 2, Issue:4

    Topics: Adult; Aged; Basal Ganglia Diseases; Biperiden; Delayed-Action Preparations; Drug Tolerance; Female;

1976
Fluphenazine enanthate induced decompensations.
    Psychosomatics, 1975, Volume: 16, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Biperiden; Female; Fluphenazine; Humans; Male; Schizophrenia

1975
[Extrapyramidal movement disorders after "Isostar Cocktail"].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1992, Volume: 140, Issue:11

    Topics: Adolescent; Basal Ganglia Diseases; Beverages; Biperiden; Dyskinesia, Drug-Induced; Food Contaminati

1992
Effects of neuroleptics on body temperature.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:2

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Biperiden; Body Temperature; Dibenzothiepins;

1988
[Study of the delayed-action form of a synthetic antiparkinsonian drug: Akineton].
    Annales medico-psychologiques, 1972, Volume: 1, Issue:5

    Topics: 1-Propanol; Adolescent; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Catatonia; D

1972
[Clinical trial of delayed-action Akinophyl (Akineton)].
    Annales medico-psychologiques, 1972, Volume: 1, Issue:5

    Topics: 1-Propanol; Adjustment Disorders; Adult; Aged; Antidepressive Agents; Antiparkinson Agents; Anxiety

1972