Page last updated: 2024-09-05

biotin and Multiple Sclerosis

biotin has been researched along with Multiple Sclerosis in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.53)18.7374
1990's1 (2.63)18.2507
2000's0 (0.00)29.6817
2010's25 (65.79)24.3611
2020's8 (21.05)2.80

Authors

AuthorsStudies
Baron-Van Evercooren, A; Garcia-Diaz, B; Levy, MJF; Mozafari, S; Sedel, F1
James, A; Kuzhively, J; Stalan, J1
Aydin, S; Batugal, A; Cabangcala, AC; Daneman, R; Gimlin, K; Hashimoto, T; Korai, M; Kotoda, M; Munji, RN; Noble-Haeusslein, LJ; Oldham, MC; Schupp, PG; Semple, BD; Sohet, F; Soung, AL; Trivedi, A; Weiner, GA1
Bouillet, B; Rouland, A1
Barbin, L; Couloume, L; Edan, G; Kerbrat, A; Laplaud, DA; Le Page, E; Le Port, D; Leray, E; Michel, L; Ory, S; Wiertlewski, S1
Cohen, JA; Goldschmidt, CH1
Gold, R; Motte, J1
Amann, M; Barro, C; Collongues, N; de Seze, J; Kappos, L; Kuhle, J; Lamy, J; Meyer, N; Moreau, T; Parmar, K; Tsagkas, C; Wuerfel, J1
Espiritu, AI; Remalante-Rayco, PPM1
Wolf, B1
Sedel, F; Tourbah, A1
Lu, Z; Sikaris, K; Trambas, C; Yen, T1
Cusini, C; De Paola, G; Piantanida, E; Sassi, L1
Mock, DM1
DiNicolantonio, JJ; McCarty, MF1
Birnbaum, G; Stulc, J1
Cross, AH; Evans, E; Piccio, L1
Arndt, C; Brassat, D; Clavelou, P; De Sèze, J; Debouverie, M; Deburghgraeve, V; Defer, G; Gout, O; Heinzlef, O; Labauge, P; Laplaud, DA; Lebrun-Frenay, C; Moreau, T; Outteryck, O; Papeix, C; Pelletier, J; Sedel, F; Toosy, A; Tourbah, A; Vighetto, A1
Koehler, VF; Mann, U; Mann, WA; Nassour, A1
Koehler, VF; Mann, U; Mann, WA1
Ceriani, L; Giovanella, L; Imperiali, M; Kasapic, D; Trimboli, P1
de Heide, LJM; Lutgers, HL; Slim, CL; van den Berg, R; Wolthuis, A1
Collongues, N; De Sèze, J; El Khoury, Y; Gulsari, V; Hellwig, P; Marcou, G; Mensah-Nyagan, AG; Patte-Mensah, C; Varnek, A1
Agius, P; Guillevin, C; Guillevin, R; Herpe, G; Maubeuge, N; Naudin, M; Philippe Neau, J; Ragot, S1
Chen, Y; Hu, ZG; Li, M; Liu, J; Sheng, H; Yuan, F; Zou, Y1
Bernard, D; Mock, DM; Sedel, F; Tourbah, A1
Bernard, D; Debruyne, D; Defer, GL; Mock, DM; Peyro Saint Paul, L1
Lu, ZX; Sikaris, KA; Trambas, CM1
Chataway, J1
Egnor, E; Siddiqui, U; Sloane, JA1
Guéchot, J; Lim, SK; Pilon, A1
Bernard, D; Chanson, P; Hercend, C; Piketty, ML; Prie, D; Sedel, F; Souberbielle, JC1
Decoudier, B; Delemer, B; Maquart, FX; Marot, D1
Kostulas, V; Link, H; Olsson, T1
Anagnostouli, M; Evangelatos, G; Ithakissios, DS; Livaniou, E; Nyalala, JO; Papageorgiou, C; Zournas, C1
Battistin, L; Bracco, F; Gallo, P; Tavolato, B1
Amaducci, L; Lolli, F1
Kostulas, VK; Lefvert, AK; Link, H1

Reviews

6 review(s) available for biotin and Multiple Sclerosis

ArticleYear
Biotin induced biochemical hyperthyroidism: a case report and review of the literature.
    Journal of medical case reports, 2023, Jun-28, Volume: 17, Issue:1

    Topics: Biotin; Hormones; Humans; Hyperthyroidism; Male; Middle Aged; Multiple Sclerosis; Thyroid Function Tests

2023
High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.
    Multiple sclerosis and related disorders, 2021, Volume: 55

    Topics: Biotin; Female; Humans; Male; Multiple Sclerosis; Randomized Controlled Trials as Topic

2021
Biotin: From Nutrition to Therapeutics.
    The Journal of nutrition, 2017, Volume: 147, Issue:8

    Topics: Animals; Biotin; Biotinylation; Carnitine; Female; Gene Expression; Hormones; Humans; Multiple Sclerosis; Nutritional Status; Pregnancy; Pregnancy Complications; Streptavidin; Vitamin B Complex

2017
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
    JAMA neurology, 2018, 08-01, Volume: 75, Issue:8

    Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Unsaturated; Folic Acid; Ginkgo biloba; Humans; Multiple Sclerosis; Niacin; Pantothenic Acid; Plant Preparations; Probiotics; Pyridoxine; Resveratrol; Riboflavin; Tea; Thiamine; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamins

2018
Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis.
    Neuropharmacology, 2016, Volume: 110, Issue:Pt B

    Topics: Animals; Biotin; Demyelinating Diseases; Disease Progression; Dose-Response Relationship, Drug; Humans; Hypoxia; Multiple Sclerosis; Vitamin B Complex

2016
Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis.
    Expert opinion on drug metabolism & toxicology, 2016, Volume: 12, Issue:3

    Topics: Animals; Biological Availability; Biotin; Disease Progression; Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Randomized Controlled Trials as Topic; Vitamin B Complex

2016

Trials

1 trial(s) available for biotin and Multiple Sclerosis

ArticleYear
MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study.
    CNS drugs, 2018, Volume: 32, Issue:7

    Topics: Biotin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Multiple Sclerosis; Optic Neuritis; Treatment Outcome; Vision Disorders; Visual Acuity; Vitamin B Complex

2018

Other Studies

31 other study(ies) available for biotin and Multiple Sclerosis

ArticleYear
High Dose Pharmaceutical Grade Biotin (MD1003) Accelerates Differentiation of Murine and Grafted Human Oligodendrocyte Progenitor Cells In Vivo.
    International journal of molecular sciences, 2022, Dec-12, Volume: 23, Issue:24

    Topics: Amyotrophic Lateral Sclerosis; Animals; Biotin; Cell Differentiation; Humans; Mice; Multiple Sclerosis; Myelin Sheath; Oligodendrocyte Precursor Cells; Oligodendroglia

2022
Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.
    Nature neuroscience, 2019, Volume: 22, Issue:11

    Topics: Animals; Biotin; Blood-Brain Barrier; Brain; Brain Injuries, Traumatic; Endothelial Cells; Infarction, Middle Cerebral Artery; Kainic Acid; Mice; Mice, Transgenic; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Permeability; Pertussis Toxin; Seizures; Signal Transduction; Stroke; Transcriptome

2019
[Intake of high dose biotin: A cause of artificial hyperthyroidism].
    La Revue de medecine interne, 2020, Volume: 41, Issue:2

    Topics: Aged; Artifacts; Biotin; Diagnosis, Differential; Diagnostic Errors; Dose-Response Relationship, Drug; False Positive Reactions; Female; Humans; Hyperthyroidism; Immunoassay; Multiple Sclerosis; Thyroid Function Tests

2020
High-dose biotin in progressive multiple sclerosis: A prospective study of 178 patients in routine clinical practice.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2020, Volume: 26, Issue:14

    Topics: Adult; Biotin; Disability Evaluation; Disease Progression; Humans; Magnetic Resonance Imaging; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies

2020
The Rise and Fall of High-Dose Biotin to Treat Progressive Multiple Sclerosis.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Biotin; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Propensity Score; Prospective Studies; Recurrence

2020
High-dose biotin in multiple sclerosis: the end of the road.
    The Lancet. Neurology, 2020, Volume: 19, Issue:12

    Topics: Biotin; Double-Blind Method; Humans; Multiple Sclerosis; Patients; Safety

2020
Biomarkers of treatment response in patients with progressive multiple sclerosis treated with high-dose pharmaceutical-grade biotin (MD1003).
    Brain and behavior, 2021, Volume: 11, Issue:2

    Topics: Bayes Theorem; Biomarkers; Biotin; Disability Evaluation; Disease Progression; Humans; Magnetic Resonance Imaging; Multiple Sclerosis

2021
Biotinidase deficiency masquerading as multiple sclerosis?
    Multiple sclerosis (Houndmills, Basingstoke, England), 2018, Volume: 24, Issue:2

    Topics: Amidohydrolases; Biotin; Biotinidase Deficiency; Double-Blind Method; Humans; Multiple Sclerosis

2018
Reply to the letter: Biotinidase deficiency masquerading as multiple sclerosis?
    Multiple sclerosis (Houndmills, Basingstoke, England), 2018, Volume: 24, Issue:2

    Topics: Amidohydrolases; Biotin; Biotinidase Deficiency; Humans; Multiple Sclerosis

2018
Depletion of biotin using streptavidin-coated microparticles: a validated solution to the problem of biotin interference in streptavidin-biotin immunoassays.
    Annals of clinical biochemistry, 2018, Volume: 55, Issue:2

    Topics: Artifacts; Biotin; Clinical Laboratory Techniques; Coated Materials, Biocompatible; Humans; Immunoassay; Multiple Sclerosis; Streptavidin; Thyroid Function Tests

2018
Apparent biochemical thyrotoxicosis due to assay interference by high-dose biotin given for multiple sclerosis.
    Journal of endocrinological investigation, 2017, Volume: 40, Issue:8

    Topics: Aged; Biological Assay; Biotin; Female; Goiter; Humans; Immunoassay; Multiple Sclerosis; Thyrotoxicosis; Vitamin B Complex

2017
Neuroprotective potential of high-dose biotin.
    Medical hypotheses, 2017, Volume: 109

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Biotin; Brain; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Extracellular Signal-Regulated MAP Kinases; Humans; Long-Term Potentiation; Microcirculation; Multiple Sclerosis; Neurogenesis; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Randomized Controlled Trials as Topic; Signal Transduction

2017
Response to letter to the editors.
    Multiple sclerosis and related disorders, 2018, Volume: 22

    Topics: Biotin; Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Vitamin B Complex

2018
Fake news? Biotin interference in thyroid immunoassays.
    Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 484

    Topics: Artifacts; Biotin; Dose-Response Relationship, Drug; Humans; Immunoassay; Male; Middle Aged; Multiple Sclerosis; Streptavidin; Thyroid Function Tests; Thyroid Gland

2018
Biotin Interference in the Measurement of Thyroid Hormone.
    Deutsches Arzteblatt international, 2018, 07-23, Volume: 115, Issue:29-30

    Topics: Biotin; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Middle Aged; Multiple Sclerosis; Thyrotropin; Vitamin B Complex

2018
Euthyroid Graves' disease with spurious hyperthyroidism: a diagnostic challenge.
    Clinical chemistry and laboratory medicine, 2019, 04-24, Volume: 57, Issue:5

    Topics: Alemtuzumab; Autoantibodies; Biotin; Graves Disease; Humans; Male; Middle Aged; Multiple Sclerosis; Receptors, Thyrotropin; Thyroid Function Tests; Thyrotropin

2019
[Apparent thyrotoxicosis in a patient with multiple sclerosis: biochemical assay interference due to high dose biotin use].
    Nederlands tijdschrift voor geneeskunde, 2018, 02-14, Volume: 162

    Topics: Antithyroid Agents; Biotin; Diagnostic Errors; Female; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay; Male; Middle Aged; Multiple Sclerosis; Thyroid Function Tests; Thyrotoxicosis; Thyroxine

2018
Serum-based differentiation between multiple sclerosis and amyotrophic lateral sclerosis by Random Forest classification of FTIR spectra.
    The Analyst, 2019, Aug-07, Volume: 144, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amyotrophic Lateral Sclerosis; Biomarkers; Biotin; Decision Trees; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Pilot Projects; Spectroscopy, Fourier Transform Infrared

2019
    Annals of clinical and translational neurology, 2019, Volume: 6, Issue:7

    Topics: Biotin; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive

2019
Determination of Anticyclic Citrullinated Peptide Based on Biotin-Streptavidin-Amplified Time-Resolved Fluoroimmunoassay.
    Journal of clinical laboratory analysis, 2015, Volume: 29, Issue:6

    Topics: Animals; Antibodies, Anti-Idiotypic; Autoantibodies; Biotin; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Fluoroimmunoassay; Humans; Immunoassay; Limit of Detection; Lupus Erythematosus, Systemic; Mixed Connective Tissue Disease; Multiple Sclerosis; Peptides, Cyclic; Prognosis; Rabbits; Scleroderma, Systemic; Sjogren's Syndrome; Streptavidin

2015
A caution regarding high-dose biotin therapy: misdiagnosis of hyperthyroidism in euthyroid patients.
    The Medical journal of Australia, 2016, Aug-15, Volume: 205, Issue:4

    Topics: Australia; Biotin; Diagnostic Errors; Dose-Response Relationship, Drug; Humans; Hyperthyroidism; Interdisciplinary Communication; Intersectoral Collaboration; Multiple Sclerosis; Thyroid Function Tests; Thyroid Hormones

2016
Biotin in progressive multiple sclerosis: A new lead?
    Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:13

    Topics: Biotin; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive

2016
Biotin supplementation in MS clinically valuable but can alter multiple blood test results.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2017, Volume: 23, Issue:4

    Topics: Biotin; Demyelinating Diseases; Double-Blind Method; Hematologic Tests; Humans; Multiple Sclerosis

2017
Biotin interferes with free thyroid hormone and thyroglobulin, but not TSH measurements using Beckman-Access immunoassays.
    Annales d'endocrinologie, 2017, Volume: 78, Issue:3

    Topics: Biotin; Diagnostic Errors; Humans; Immunoassay; Multiple Sclerosis; Thyroglobulin; Thyroid Hormones; Thyrotropin

2017
High-dose biotin therapy leading to false biochemical endocrine profiles: validation of a simple method to overcome biotin interference.
    Clinical chemistry and laboratory medicine, 2017, May-01, Volume: 55, Issue:6

    Topics: Artifacts; Biotin; Blood Chemical Analysis; Case-Control Studies; Dose-Response Relationship, Drug; Endocrine System; Female; Hormones; Humans; Immunoassay; Male; Multiple Sclerosis; Streptavidin

2017
Consistent, but Totally Misleading, Thyroid Function Test Results.
    Clinical chemistry, 2017, Volume: 63, Issue:3

    Topics: Aged; Antibody Affinity; Biotin; False Positive Reactions; Humans; Hyperthyroidism; Immunoassay; Male; Multiple Sclerosis; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronine

2017
Improved detection of oligoclonal IgG in cerebrospinal fluid by isoelectric focusing in agarose, double-antibody peroxidase labeling, and avidin-biotin amplification.
    Clinical chemistry, 1984, Volume: 30, Issue:7

    Topics: Avidin; Biotin; Central Nervous System Diseases; Collodion; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoglobulin G; Indicators and Reagents; Infections; Isoelectric Focusing; Multiple Sclerosis; Rosaniline Dyes; Sepharose

1984
Cerebrospinal fluid levels of biotin in various neurological disorders.
    Acta neurologica Scandinavica, 1999, Volume: 99, Issue:6

    Topics: Adult; Aged; Biomarkers; Biotin; Case-Control Studies; Epilepsy; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Nervous System Diseases; Reference Values

1999
Detection of IgG oligoclonal bands in unconcentrated CSF by means of agarose isoelectric focusing, double immunofixation peroxidase staining and avidin-biotin amplification.
    Italian journal of neurological sciences, 1985, Volume: 6, Issue:3

    Topics: Avidin; Biotin; Humans; Immunoenzyme Techniques; Immunoglobulins; Isoelectric Focusing; Monoclonal Gammopathy of Undetermined Significance; Multiple Sclerosis; Nervous System Diseases; Oligoclonal Bands; Ovalbumin; Sepharose; Staining and Labeling

1985
Measurement of free kappa immunoglobulin light chains in the cerebrospinal fluid by a competitive avidin-biotin ELISA.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Jun-30, Volume: 182, Issue:2

    Topics: Avidin; Biotin; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin kappa-Chains; Multiple Sclerosis

1989
Oligoclonal IgG bands in cerebrospinal fluid. Principles for demonstration and interpretation based on findings in 1114 neurological patients.
    Archives of neurology, 1987, Volume: 44, Issue:10

    Topics: Adult; Aged; Avidin; Biotin; Electrophoresis, Agar Gel; Female; Humans; Immunoglobulin G; Isoelectric Focusing; Male; Middle Aged; Multiple Sclerosis; Nervous System Diseases

1987