biotin has been researched along with Disease Models, Animal in 167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.40) | 18.7374 |
| 1990's | 16 (9.58) | 18.2507 |
| 2000's | 53 (31.74) | 29.6817 |
| 2010's | 87 (52.10) | 24.3611 |
| 2020's | 7 (4.19) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Adam, M; Al-Dalahmah, O; Casaccia, P; Dansu, DK; Davidson, S; Flowers, XE; Fraenkel, E; Gold, MP; Goldman, JE; Hickman, RA; Khan, F; Lau, A; Lim, RG; McClure, N; Menon, V; Michael, N; Miramontes, R; Miyoshi, E; Ofori, K; Park, HJ; Paryani, F; Reidling, JC; Reyes-Ortiz, AM; Swarup, V; Tang, A; Tang, G; Thompson, LM; Vonsattel, JP; Wu, J | 1 |
| Bay, HH; Çavdar, S; Onat, F; Özkan, M | 1 |
| Brown, CM; Brown, ED; Carfrae, LA; Chun, J; Coombes, BK; Junop, MS; MacNair, CR; Rao, VN; Tsai, CN; Weber, BS; Zlitni, S | 1 |
| Akhlaghi, M; Beiki, D; Geramifar, P; Gholipour, N; Mokhtari Kheirabadi, A | 1 |
| Beal, MF; Calingasan, NY; Colsch, B; Ferrer, I; Fourcade, S; Goicoechea, L; Launay, N; Parameswaran, J; Pujol, A; Ruiz, M; Schlüter, A; Sedel, F; Seyer, A | 1 |
| Feany, MB; Frost, B; Lohr, KM; Scherzer, C | 1 |
| Asara, JM; Bosch, JA; Branon, T; Carey, DK; Carr, SA; Droujinine, IA; Guo, J; Hu, Y; McMahon, AP; McMahon, JA; Meyer, AS; Mu, L; Perrimon, N; Rocco, D; Svinkina, T; Tabatabai, A; Ting, AY; Udeshi, ND; Wang, D; Yang, R; Zeng, R | 1 |
| Huang, YH; Liu, PH; Tseng, CY; Tseng, GF; Yeh, TY | 1 |
| Cheng, X; Liang, Y; Luo, Y; Mu, X; Qu, H; Sun, Y; Wang, H; Zhao, C | 1 |
| Adetunji, MO; Chen, S; Li, W; Takahama, S; Tomarev, SI; Zhao, T | 1 |
| Butler, BE; de la Rua, A; Lomber, SG; Ward-Able, T | 1 |
| Cheng, X; Jolkkonen, J; Liu, TT; Mu, XP; Qu, HL; Song, B; Sun, XY; Wang, HB; Xiao, T; Yang, L; Zhao, CS; Zhao, SS; Zhou, ZK | 1 |
| Bang, S; Chang, W; Chen, G; Gong, X; Han, Q; Im, ST; Ji, RR; Kim, YH; Lee, SY; Liu, D; Luo, X; Strong, JA; Yoo, J; Zhang, JM; Zhang, MZ | 1 |
| Bass, B; Brown, A; Geremia, NM; Hryciw, T; Liu, T; Mailloux, J; McKillop, WM; Xu, X | 1 |
| Cross, AH; Evans, E; Piccio, L | 1 |
| Geoffroy, CG; Kim, JJ; Kim, ND; Meves, JM; Zheng, B | 1 |
| An, J; Cheng, K; Li, C; Liu, B; Song, YY; Xuan, Y; Yang, XQ; Zhang, MZ; Zhang, XS; Zhao, YD | 1 |
| Asghar, S; Dai, S; Feng, S; Jin, L; Shao, F; Wang, Y; Xiao, Y; Xu, M | 1 |
| Che, J; Dong, R; Dong, X; Guo, R; Hu, Y; Huang, F; Jin, Y; Li, X; Li, Y; Lin, N; Song, R; Tan, B; Yan, Y; Zhang, B; Zhuang, Y | 1 |
| Chabot, N; Kok, MA; Lomber, SG; Wong, C | 2 |
| Fallon, JB; Landry, TG; Shepherd, RK; Wise, AK | 1 |
| Lee, CS; Reyes, BA; Valentino, RJ; Van Bockstaele, EJ; Wood, SK; Zhang, XY | 1 |
| Deng, LX; Deng, P; Liu, NK; Ruan, Y; Smith, GM; Wen, X; Xu, XM; Xu, ZC | 1 |
| Baker, J; Bergeron, M; Diep, L; Dofiles, L; Fauss, D; Motter, R; Rodrigues, MA; Seto, P; Tanaka, K; Yang, Y; You, M | 1 |
| Chen, T; Li, YQ; Qu, J; Wang, W; Wang, XL; Wu, SX; Yanagawa, Y; Zhang, T | 1 |
| Arreto, CD; Bourgeais, L; Condes-Lara, M; Jay, T; Noseda, R; Robert, C; Villanueva, L | 1 |
| Chaikof, EL; Dorr, BM; Haller, CA; Hanson, SR; Hinds, MT; Hurst, S; Krishnamurthy, V; Liu, DR; Marzec, UM; Qu, Z | 1 |
| Hu, J; She, Y; Smith, GM; Wang, X; Xu, XM | 1 |
| Blanchemain, N; Chai, F; Haulon, S; Maton, M; Maurel, B | 1 |
| Chabot, N; Kok, MA; Lomber, SG | 1 |
| Bucak, YY; Çelebi, S; Erdurmus, M; Kükner, A; Terzi, EH | 1 |
| Heredia-Antúnez, A; Hernández-González, R; Hernández-Vázquez, A; Ibarra-González, I; Ortega-Cuellar, D; Pindolia, K; Velázquez-Arellano, A; Wolf, B | 1 |
| Garfoot, AL; Rappleye, CA; Zemska, O | 1 |
| Bachmann, LC; Felder, P; Lindau, NT; Schwab, ME | 1 |
| Cardwell, C; Li, H; Pindolia, K; Wolf, B | 1 |
| Chiang, YT; Lo, CL | 1 |
| Sharp, KG; Steward, O; Yee, KM | 1 |
| Bassot, E; Boulland, JL; Bras, H; Chaudhry, FA; Coulon, P; Esclapez, M; Ferhat, L; Soussi, R; Storm-Mathisen, J | 1 |
| Jolkkonen, J; Qu, H; Tang, X; Xiao, T; Zhao, C; Zhao, D; Zhao, M; Zhao, S | 1 |
| Chopp, M; Cui, Y; Li, Y; Liu, Z; Lu, M; Pekny, M; Roberts, C; Wilhelmsson, U | 1 |
| Hayat, U; Li, H; Li, S; Liu, J; Longo, FM; Ohtake, Y; Park, D; Selzer, ME; Xu, B | 1 |
| Arisato, H; Assinck, P; Biernaskie, J; Borisoff, J; Bretzner, F; Jiang, Y; Liu, J; Miller, FD; Plunet, WT; Sparling, JS; Tetzlaff, W | 1 |
| Ghosal, A; Jellbauer, S; Kapadia, R; Raffatellu, M; Said, HM | 1 |
| Chakravartty, V; Chin, CY; Crispell, EK; Cronan, JE; Feng, Y; Gao, R; Weiss, DS | 1 |
| Atobe, Y; Funakoshi, K; Kadota, T; Takiguchi, M | 1 |
| Wolf, B | 1 |
| Cafferty, WB; Fink, KL; Strittmatter, SM | 1 |
| Chen, K; Cheng, P; Gao, S; Hu, S; Huang, H; Sun, X; Yu, W | 1 |
| Amer, A; Martin, JH; Ryan, D; Song, W | 1 |
| Dong, C; Jia, B; Liu, Z; Shi, J; Wang, F; Yang, S; Zhao, H; Zhong, L | 1 |
| Hida, H; Isa, K; Isa, T; Ishida, A; Kobayashi, K; Umeda, T | 1 |
| Hu, Q; Kang, LK; Wang, T; Wang, XY; Wei, HM; Wen, ZH; Xu, CM | 1 |
| Bailey, SM; Chatham, JC; Chow, CW; Hamm, JA; He, L; McGinnis, GR; Peliciari-Garcia, RA; Reddy, A; Rowe, GC; Sams, D; Young, ME | 1 |
| Fan, X; Fu, X; Li, D; Lin, C; Liu, J; Sun, Y; Wang, L; Zhang, X; Zhou, X; Zuo, M | 1 |
| Brown, A; Hryciw, T; Liu, T; McKillop, WM; Ossowski, NM; Rubinger, L; Xu, K; York, EM | 1 |
| Abshire, SM; Cameron, AA; Duale, H; Hou, S; Lyttle, TS; Rabchevsky, AG | 1 |
| Hofstadter, M; Sharp, K; Steward, O; Tessier-Lavigne, M; Yee, KM; Zheng, B | 1 |
| Chopp, M; Li, Y; Liu, Z; Savant-Bhonsale, S; Zhang, X | 1 |
| Fan, Y; Lei, Z; Ruan, YW; Xu, ZC; Zou, B | 1 |
| Ayers, KL; Culver, JP; Finley, AM; Goldberg, MP; Lapash Daniels, CM | 1 |
| Lei, Z; Li, Y; Xu, ZC | 1 |
| Sawai, C; Takano, T; Takeuchi, Y | 1 |
| Bregman, BS; Dai, H; Finn, T; Hamers, FP; Hockenbury, N; MacArthur, L; Mansfield, K; McAtee, M; McHugh, B; Tidwell, JL | 1 |
| Anderson, KD; Sharp, KG; Steward, O | 1 |
| Bowles, N; Gaspar, RC; Hepler, RW; Joyce, JG; Shughrue, PJ; Villarreal, SA | 1 |
| Chen, B; Ellis-Behnke, RG; Nan, Y; Pu, M; So, KF; Xiao, C | 1 |
| Brazda, N; Müller, HW; Schiwy, N | 1 |
| Bigbee, AJ; de Leon, RD; Edgerton, VR; Guu, JJ; Joynes, RL; London, NJ; Roy, RR; Tillakaratne, NJ; Zhong, H; Ziegler, MD | 1 |
| Carretta, D; Del Tongo, C; Granato, A; Minciacchi, D; Nosi, D | 1 |
| Calamandrei, G; Cutuli, D; De Bartolo, P; Foti, F; Gelfo, F; Laricchiuta, D; Petrosini, L; Ricceri, L; Scattoni, ML | 1 |
| Cafferty, WB; Duffy, P; Huebner, E; Strittmatter, SM | 1 |
| Chopp, M; Liu, Z; Mahmood, A; Meng, Y; Qu, C; Xiong, Y; Zhang, Y | 1 |
| Blitzer, M; Guo, C; Jordan, M; Matthews, N; Mock, DM; Pindolia, K; Strovel, E; Wolf, B | 1 |
| Garbern, JC; Minami, E; Murry, CE; Stayton, PS | 1 |
| Kent, DT; Odelberg, SJ; Zukor, KA | 1 |
| Barth, DS; Benison, AM; Chumachenko, S; Falci, SP; Harrison, JA; Maier, SF; Watkins, LR | 1 |
| Alame, G; Cazenave, JP; Freund, M; Gachet, C; Gaertner, S; Hechler, B; Leguay, C; Petitou, M | 1 |
| Appelbaum, FR; Axtman, A; Bäck, T; Fisher, DR; Frayo, S; Gopal, AK; Green, DJ; Hamlin, DK; Kenoyer, AL; Lin, Y; Orgun, N; Orozco, J; Pagel, JM; Park, SI; Press, OW; Shenoi, J; Wilbur, DS | 1 |
| Andres, RH; Bliss, TM; Horie, N; Keren-Gill, H; Manley, NC; McMillan, EL; Pereira, MP; Schaar, BT; Sheikh, LA; Slikker, W; Steinberg, GK; Sun, G; Svendsen, CN; Zhan, K | 1 |
| Du, BL; He, LM; Li, Y; Quan, DP; Wu, JL; Xiong, Y; Zeng, CG; Zeng, YS; Zhang, W | 1 |
| Chiang, A; Iffrig, E; Slade, PG; Tannenbaum, SR; Williams, MV; Wishnok, JS | 1 |
| Artiukhina, ZE; Ekimova, IV; Guzhova, IV; Pastukhov, IuF; Romanova, IV | 1 |
| Aldrich, CC; Barry, CE; Blumenthal, A; Boshoff, HI; Ehrt, S; Eoh, H; Klotzsche, M; Manjunatha, U; Rhee, K; Schnappinger, D; Wilson, DJ; Woong Park, S | 1 |
| Arvanian, VL; Bowers, WJ; Fawcett, JW; García-Alías, G; Horner, PJ; Mendell, LM; Petrosyan, HA; Schnell, L | 1 |
| Bacigaluppi, M; Doeppner, TR; ElAli, A; Guo, Z; Hagen, SI; Hermann, DM; Herz, J; Kilic, E; Kilic, U; Pluchino, S; Reinboth, BS; Reitmeir, R; Zechariah, A | 1 |
| Furukawa, Y; Kagawa, Y; Kamiyama, S; Komai, M; Sasaki, Y; Shimizu, M; Shirakawa, H; Sone, H | 1 |
| Bard, F; Buttini, M; Comery, TA; Games, D; Gardai, SJ; Kinney, GG; Nishioka, C; Schenk, D; Seubert, P; Zago, W | 1 |
| Duricki, DA; Moon, LD; Soleman, S; Yip, PK | 1 |
| Hayano, Y; Nakagawa, H; Ueno, M; Yamashita, T | 1 |
| Adelson, JD; Barreto, GE; Brott, BK; Djurisic, M; Giffard, RG; Kim, T; Naserke, T; Ouyang, YB; Shatz, CJ; Xiong, X; Xu, L | 1 |
| El Maarouf, A; Ghosh, M; Melendez, K; Patel, S; Pearse, DD; Puentes, R; Rutishauser, U; Tuesta, LM | 1 |
| Hu, JG; Lü, HZ; Shen, L; Wang, HJ; Wang, QY; Wang, R; Xi, J; Zhang, C; Zhou, JS | 1 |
| Aoki, J; Ebina, K; Kumagai, T; Sato, A | 1 |
| Heijnen, CJ; Huppi, PS; Kavelaars, A; Sizonenko, S; van Bel, F; van de Looij, Y; van Velthoven, CT; Zijlstra, J | 1 |
| Feng, J; Li, Q; Qin, X; Wang, T; Wu, X | 1 |
| Chen, X; Cui, L; Guan, T; Kong, J; Li, C; Li, XM; Shang, H; Zhang, X | 1 |
| Chen, X; Cui, L; Guan, T; Kong, J; Li, C; Li, XM; Shang, H | 1 |
| Grove, KL; Kirigiti, M; Lee, SJ; Lindsley, SR; Loche, A; Madden, CJ; Morrison, SF; Smith, MS | 1 |
| Chopp, M; Mahmood, A; Qu, C; Wu, H; Xiong, Y | 1 |
| Chung, I; Frankfort, BJ; Gross, RL; Khan, AK; Pang, JJ; Tse, DY; Wu, SM; Yang, Z | 1 |
| Alarcón, C; Darian-Smith, C; Lilak, A | 1 |
| Dai, J; Luo, Y; Zhou, Y | 1 |
| Bär, D; Blomgren, K; Groenendaal, F; Hagberg, H; Kops, N; Koster, J; Nicolay, K; Peeters-Scholte, C; van Bel, F; van Buul-Offers, S; van den Tweel, E; Veldhuis, W; Zhu, C | 1 |
| Kuypers, FA; Manodori, AB | 1 |
| Chiu, GN; Fung, VW; Mayer, LD | 1 |
| Granato, A; Van Pelt, J | 1 |
| Groenendaal, F; Peeters-Scholte, C; van Bel, F; van den Tweel, E | 1 |
| Goto, Y; O'Donnell, P | 1 |
| Corti, A | 1 |
| Blomgren, K; Hagberg, H; Peeters-Scholte, C; Qiu, L; Wang, X; Zhu, C | 1 |
| Kwon, BK; Liu, J; Liu, ZW; Oschipok, L; Teh, J; Tetzlaff, W | 1 |
| McGee, A; Ment, L; Schwartz, M; Stewart, WB; Strittmatter, S; Takizawa, B; Weiss, J; Zhang, H | 1 |
| Anderson, KD; Gunawan, A; Steward, O | 2 |
| Bareyre, FM; Clouse, AK; Hoover, RC; Lenzlinger, PM; Luginbuhl, A; Marklund, N; McIntosh, TK; Morganti-Kossmann, C; Motta, M; Pape, R; Saatman, KE; Schwab, ME; Shimizu, S; Thompson, HJ | 1 |
| Budel, S; Engber, TM; Ji, B; Li, M; Pepinsky, RB; Relton, JK; Strittmatter, SM; Walus, L | 1 |
| Harman, CD; Weber, AJ | 1 |
| Chan, CC; Khodarahmi, K; Liu, J; Oschipok, LW; Steeves, JD; Sutherland, D; Tetzlaff, W | 1 |
| Mårtensson, L; Nilsson, R; Ohlsson, T; Senter, P; Sjögren, HO; Strand, SE; Tennvall, J; Wang, Z | 1 |
| Shimkets, RA | 1 |
| Bauer, S; Patterson, PH | 1 |
| Jiang, XF; Li, GP; Zhang, H; Zhang, J; Zhu, CM | 1 |
| Blits, B; Boer, GJ; Eggers, R; Hamers, FP; Hendriks, WT; Ruitenberg, MJ; Verhaagen, J | 1 |
| Fujitani, M; Hata, K; Kitajo, K; Koda, M; Kubo, T; Moriya, H; Nishio, Y; Seto, M; Taniguchi, J; Yamashita, T | 1 |
| Bregman, BS; Dai, HN; Kim, BG; Lynskey, JV; McAtee, M | 1 |
| Glaser, J; Gonzalez, R; Keirstead, HS; Sadr, E | 1 |
| Bollnow, MR; Emerick, AJ; Kartje, GL; O'Brien, TE; Ramic, M; Tsai, SY | 1 |
| Bye, N; Dziegielewska, KM; Ek, CJ; Habgood, MD; Lane, MA; Morganti-Kossmann, C; Potter, A; Saunders, NR | 1 |
| Hara, M; Morikawa, T; Ohata, K; Sakamoto, H; Takami, T; Tsuyuguchi, N | 1 |
| Dobrowolski, R; Kretz, M; Markopoulos, C; Schnichels, M; Schwarz, G; Willecke, K; Winterhager, E; Wörsdörfer, P | 1 |
| Armstrong, S; Fenrich, KK; MacDermid, VE; Meehan, CF; Neuber-Hess, MS; Rose, PK; Skelton, N | 1 |
| Alpár, A; Arendt, T; Gärtner, U; Seeger, G; Ueberham, U | 1 |
| Groenendaal, F; Heijnen, CJ; Kavelaars, A; Nijboer, CH; van Bel, F | 1 |
| Boire, D; Bronchti, G; Chabot, N; Miceli, D; Robert, S; Tremblay, R | 1 |
| Allene, C; Amendola, J; Bories, C; Durand, J; Gueritaud, JP; Lamotte d'Incamps, B; Liabeuf, S; Pambo-Pambo, A | 1 |
| Järlebark, L; Jin, Z; Ulfendahl, M | 1 |
| Akrimi, SF; Bradbury, EJ; Fawcett, JW; García-Alías, G; Lin, R; Story, D | 1 |
| Chen, Q; Shine, HD; Smith, GM | 1 |
| Deng, P; Jiang, Y; Li, ZJ; Liu, ZF; Wang, J; Xu, J; Yang, L | 1 |
| Hofstadter, M; Sharp, K; Steward, O; Yee, KM | 1 |
| Koerber, HR; Kullmann, FA; McIlwrath, SL; Woodbury, CJ | 1 |
| Olsen, I; Partridge, T; Zoller, J | 1 |
| Akahori, F; Masaoka, T; Nomura, Y; Shirota, K; Tanaka, M; Une, Y; Yanagi, M | 1 |
| Mock, DM; Patel, A; Wang, KS | 1 |
| Altrup, U; Speckmann, EJ; Wiemann, M; Wittkowski, W | 1 |
| Heegaard, NH; Larsen, KL; Olsen, DT | 1 |
| Furukawa, Y; Ito, M; Komai, M; Maebashi, M; Osada, K; Zhang, H | 1 |
| Furukawa, Y; Osada, K; Sone, H; Zhang, H | 1 |
| Manning, KL; McDonald, TP | 1 |
| Matsuno, H; Morita, I; Nezuka, T; Nishioka, K; Sakai, K; Shirai, T; Tsuji, H | 1 |
| Hattori, T; Kawamura, H; Shindo, S | 1 |
| Bertagnolli, MM; Bilinski, RT; Churchill, MR; Dannenberg, AJ; Mahmoud, NN; Martucci, C; Mestre, J; Newmark, H | 1 |
| Chaudhuri, TR; Fleck, M; Liu, HG; Mountz, JD; Mountz, JM; Smyth, CA; Wu, Q; Zinn, KR | 1 |
| Di Rocco, C; Di Rocco, F; Gaglini, P; Giannetti, S; Granato, A | 1 |
| Freeze, HH; Manzi, A; Panneerselvam, K; Srikrishna, G; Toomre, DK; Varki, A; Varki, NM | 1 |
| Furuta, K; Hatanaka, H; Ishikawa, Y; Nakatsuka, D; Namura, S; Satoh, T; Sugie, Y; Suzuki, M; Tomokiyo, K; Watanabe, Y | 1 |
| Balaguero, N; Barclay, J; Brodbeck, J; Canti, C; Courtney, JM; Davies, A; Dolphin, AC; Hunt, SP; Meir, A; Moss, FJ; Page, KM; Pratt, WS; Rees, M | 1 |
| Dias, T; Hommes, FA; Schrijver, J | 1 |
| Hussienzadha, S; Oveisi, F; Said, HM; Vaziri, ND | 1 |
| Bhardwaj, B; Rybak, LP; Scott, V; Weberg, AD; Whitworth, C | 1 |
| Kitamura, K; Otsuji, E; Sawai, K; Takahashi, T; Yamaguchi, T; Yokota, T | 1 |
| Bagherzadeh, A; Mock, D; Said, HM; Sharifian, A | 1 |
| Miyaji, M; Nakajima, H; Nakamura, A; Nishimura, K; Suzuki, H; Taguchi, H | 1 |
| Mock, DM; Mock, NI; Weintraub, S | 1 |
| Marchetti, M; Moruzzi, G | 1 |
2 review(s) available for biotin and Disease Models, Animal
| Article | Year |
|---|---|
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Unsaturated; Folic Acid; Ginkgo biloba; Humans; Multiple Sclerosis; Niacin; Pantothenic Acid; Plant Preparations; Probiotics; Pyridoxine; Resveratrol; Riboflavin; Tea; Thiamine; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamins | 2018 |
Biotinidase deficiency and our champagne legacy.
Topics: Animals; Biotin; Biotinidase; Biotinidase Deficiency; Disease Models, Animal; Gene Expression; History, 20th Century; History, 21st Century; Humans; Infant, Newborn; Mice; Mutation; Neonatal Screening; Translational Research, Biomedical; United States | 2016 |
1 trial(s) available for biotin and Disease Models, Animal
| Article | Year |
|---|---|
Delayed treatment with chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats.
Topics: Acoustic Stimulation; Aging; Amidines; Analysis of Variance; Animals; Biotin; Brain Infarction; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Double-Blind Method; Female; Forelimb; Functional Laterality; Gait Disorders, Neurologic; Injections, Spinal; Male; Movement Disorders; Neuronal Plasticity; Neurons; Plant Lectins; Psychomotor Performance; Pyramidal Tracts; Rats; Rats, Long-Evans; Receptors, N-Acetylglucosamine; Recovery of Function; Sensation Disorders; Stroke; Time Factors | 2012 |
164 other study(ies) available for biotin and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Topics: Animals; Biotin; Dietary Supplements; Disease Models, Animal; Humans; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Oligodendroglia; Solitary Nucleus; Thiamine | 2022 |
Do the Dento-Thalamic Connections of Genetic Absence Epilepsy Rats from Strasbourg Differ from Those of Control Wistar Rats?
Topics: Animals; Biotin; Cerebellar Nuclei; Cerebral Cortex; Dextrans; Disease Models, Animal; Epilepsy; Epilepsy, Absence; Magnetic Resonance Imaging; Male; Rats; Rats, Inbred Strains; Rats, Wistar; Thalamus | 2019 |
Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacterial Proteins; Biotin; Disease Models, Animal; Drug Resistance, Bacterial; Humans; Mice; Microbial Sensitivity Tests; Models, Molecular; Mutation; Species Specificity; Streptavidin; Transaminases | 2020 |
Development of Ga-68 labeled, biotinylated thiosemicarbazone dextran-coated iron oxide nanoparticles as multimodal PET/MRI probe.
Topics: Animals; Biotin; Cell Line, Tumor; Cell Survival; Dextrans; Disease Models, Animal; Ferric Compounds; Fibrosarcoma; Gallium Radioisotopes; Heterografts; Humans; Magnetic Resonance Imaging; Metal Nanoparticles; Mice; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Thiosemicarbazones | 2020 |
High-dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy.
Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; Axons; Biotin; Cell Line; Disease Models, Animal; Energy Metabolism; Homeostasis; Humans; Lipids; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Sterol Regulatory Element Binding Protein 1 | 2020 |
Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model.
Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Biotin; Biotinylation; Brain; Disease Models, Animal; Drosophila melanogaster; Female; Gene Expression Regulation; Genetic Testing; Humans; Male; Mice; Mitochondria; Nerve Degeneration; Neurons; Neurotoxins; Tauopathies | 2020 |
Proteomics of protein trafficking by in vivo tissue-specific labeling.
Topics: Animals; Animals, Genetically Modified; Biotin; Biotinylation; Carbon-Nitrogen Ligases; Cell Line; Disease Models, Animal; Drosophila; Embryonic Stem Cells; Escherichia coli Proteins; Female; Humans; Male; Mice; Protein Engineering; Protein Transport; Proteomics; Repressor Proteins; Staining and Labeling; Tandem Mass Spectrometry; Teratoma | 2021 |
Effects of epidural compression on stellate neurons and thalamocortical afferent fibers in the rat primary somatosensory cortex.
Topics: Acetophenones; Afferent Pathways; Aldehydes; Animals; Antioxidants; Ascorbic Acid; Biotin; Brain Injuries; Dendrites; Dextrans; Disease Models, Animal; Electron Transport Complex IV; Epidural Space; Functional Laterality; Male; Neurons; Oxidative Stress; Rats; Somatosensory Cortex; Thalamus; Time Factors; Tyrosine | 2017 |
dl-3-n-butylphthalide promotes neuroplasticity and motor recovery in stroke rats.
Topics: Animals; Benzofurans; Biotin; Brain Infarction; Dextrans; Disease Models, Animal; Disks Large Homolog 4 Protein; Doublecortin Protein; Endothelin-1; Male; Motor Activity; Neuronal Plasticity; Nogo Proteins; Nogo Receptor 1; Platelet Aggregation Inhibitors; Psychomotor Performance; Rats; Rats, Wistar; Recovery of Function; Signal Transduction; Stroke; Vesicular Glutamate Transport Protein 1 | 2017 |
Retinal Astrocytes and GABAergic Wide-Field Amacrine Cells Express PDGFRα: Connection to Retinal Ganglion Cell Neuroprotection by PDGF-AA.
Topics: Amacrine Cells; Animals; Astrocytes; Biotin; Blotting, Western; Cell Survival; Cells, Cultured; Choline O-Acetyltransferase; Disease Models, Animal; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Fluorescence; Neuroprotection; Neuroprotective Agents; Platelet-Derived Growth Factor; Receptor, Platelet-Derived Growth Factor alpha; Retinal Ganglion Cells | 2017 |
Cortical and thalamic connectivity to the second auditory cortex of the cat is resilient to the onset of deafness.
Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Auditory Cortex; Auditory Pathways; Biotin; Brain Mapping; Cats; Deafness; Dextrans; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Neuroanatomical Tract-Tracing Techniques; Thalamus; Time Factors | 2018 |
Inhibition of Nkcc1 promotes axonal growth and motor recovery in ischemic rats.
Topics: Animals; Axons; Biotin; Brain Infarction; Brain Ischemia; Brain-Derived Neurotrophic Factor; Bumetanide; Dextrans; Disease Models, Animal; Disks Large Homolog 4 Protein; Male; Motor Activity; Nogo Proteins; Psychomotor Disorders; Pyramidal Tracts; Rats; Rats, Wistar; Recovery of Function; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Vesicular Glutamate Transport Protein 1 | 2017 |
Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7 : Differential activities of Nav1.7-targeting monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Biotin; Cells, Cultured; Disease Models, Animal; Female; Ganglia, Spinal; HEK293 Cells; Humans; Hybridomas; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; NAV1.5 Voltage-Gated Sodium Channel; NAV1.7 Voltage-Gated Sodium Channel; Neuralgia; Protein Binding; Recombinant Proteins; Sensory Receptor Cells | 2018 |
Sox9 knockout mice have improved recovery following stroke.
Topics: Animals; Biotin; Central Nervous System; Cerebrovascular Circulation; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Exploratory Behavior; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice; Mice, Knockout; Muscle Strength; Phosphopyruvate Hydratase; Plant Lectins; Receptors, N-Acetylglucosamine; Recovery of Function; RNA, Messenger; SOX9 Transcription Factor; Time Factors | 2018 |
Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury.
Topics: Age Factors; Animals; Axons; Biotin; Central Nervous System Diseases; Dextrans; Disease Models, Animal; Food Deprivation; Functional Laterality; Gray Matter; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Neurons; Nogo Proteins; Oligodendroglia; Pyramidal Tracts; Recovery of Function; Transduction, Genetic; Vesicular Glutamate Transport Protein 1 | 2018 |
Topics: Animals; Antineoplastic Agents; Biotin; Combined Modality Therapy; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Therapy; Genetic Therapy; HeLa Cells; Humans; Hyperthermia, Induced; Mice, Nude; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Oligonucleotides, Antisense; Phototherapy; Radiotherapy, Image-Guided; Theranostic Nanomedicine; Treatment Outcome | 2018 |
Mesenchymal stem cells-curcumin loaded chitosan nanoparticles hybrid vectors for tumor-tropic therapy.
Topics: Animals; Biotin; Cell Movement; Cell Survival; Chitosan; Curcumin; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fluorescent Antibody Technique; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Nanoparticles; Neoplasms; Polymers; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
GSH Activated Biotin-tagged Near-Infrared Probe for Efficient Cancer Imaging.
Topics: Animals; Biotin; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Endocytosis; Glutathione; Humans; Models, Biological; Molecular Probes; Neoplasm Transplantation; Optical Imaging; Osteosarcoma; Photoacoustic Techniques; Transplantation, Heterologous | 2019 |
Modified areal cartography in auditory cortex following early- and late-onset deafness.
Topics: Acoustic Stimulation; Age of Onset; Analysis of Variance; Animals; Auditory Cortex; Biotin; Cats; Cochlea; Deafness; Dextrans; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Neurofilament Proteins; Sensory Deprivation; Stereotaxic Techniques | 2014 |
Chronic neurotrophin delivery promotes ectopic neurite growth from the spiral ganglion of deafened cochleae without compromising the spatial selectivity of cochlear implants.
Topics: Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; Biotin; Cochlea; Cochlear Implantation; Deafness; Dextrans; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Female; Guinea Pigs; Inferior Colliculi; Male; Nerve Growth Factors; Neurites; Neurofilament Proteins; Neurons; Spiral Ganglion | 2013 |
Cellular adaptations of dorsal raphe serotonin neurons associated with the development of active coping in response to social stress.
Topics: Action Potentials; Adaptation, Biological; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Biotin; Corticotropin-Releasing Hormone; Disease Models, Animal; Individuality; Male; Microscopy, Immunoelectron; Peptide Fragments; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Corticotropin-Releasing Hormone; Serotonergic Neurons; Serotonin; Stress, Psychological | 2013 |
A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury.
Topics: Animals; Biotin; Cell Count; Dextrans; Disease Models, Animal; Electric Stimulation; Evoked Potentials; Female; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Guided Tissue Regeneration, Periodontal; In Vitro Techniques; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Motor Activity; Myelin P0 Protein; Nerve Regeneration; Neural Pathways; Rats; Rats, Sprague-Dawley; Recovery of Function; Schwann Cells; Spinal Cord; Spinal Cord Injuries; Stilbamidines; Synaptophysin; Time Factors; Transduction, Genetic | 2013 |
Development of an enzyme-linked immunosorbent assay (ELISA) to measure the level of tyrosine hydroxylase protein in brain tissue from Parkinson's disease models.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Biotin; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Intermediate Filament Proteins; Male; Mice; Mice, Inbred C57BL; Mutation; Parkinson Disease; Rats; Rats, Sprague-Dawley; Specimen Handling; Tyrosine 3-Monooxygenase | 2013 |
Neurokinin-1 receptor-expressing neurons that contain serotonin and gamma-aminobutyric acid in the rat rostroventromedial medulla are involved in pain processing.
Topics: Animals; Biotin; Cell Count; Dextrans; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Pain; Rats; Receptors, Neurokinin-1; Serotonin; Stilbamidines; Substance P | 2013 |
Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches.
Topics: Action Potentials; Animals; Biotin; Corticosterone; Dextrans; Disease Models, Animal; GABA Antagonists; GABA-A Receptor Agonists; Male; Muscimol; Neural Pathways; Neurons; Paraventricular Hypothalamic Nucleus; Physical Stimulation; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyridazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Stilbamidines; Stress, Psychological; Trigeminal Nuclei; Tryptamines | 2013 |
Immobilization of actively thromboresistant assemblies on sterile blood-contacting surfaces.
Topics: Amines; Aminoacyltransferases; Animals; Azides; Bacterial Proteins; Biotin; Blood Platelets; Coated Materials, Biocompatible; Cysteine Endopeptidases; Disease Models, Animal; Heparin; Immobilized Proteins; Papio; Polyethylene Glycols; Polytetrafluoroethylene; Staphylococcus aureus; Thrombomodulin; Thrombosis | 2014 |
Cortical PKC inhibition promotes axonal regeneration of the corticospinal tract and forelimb functional recovery after cervical dorsal spinal hemisection in adult rats.
Topics: Animals; Biotin; Carbazoles; Cells, Cultured; Cerebral Cortex; Chondroitin ABC Lyase; Dextrans; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Female; Forelimb; Functional Laterality; Glial Fibrillary Acidic Protein; Male; Nerve Regeneration; Neurons; Pregnancy; Protein Kinase C; Psychomotor Performance; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries | 2014 |
In stent restenosis and thrombosis assessment after EP224283 injection in a rat model.
Topics: Angioplasty, Balloon; Animals; Aorta; Biotin; Cell Proliferation; Disease Models, Animal; Factor XI; Graft Occlusion, Vascular; Male; Muscle, Smooth, Vascular; Neointima; Oligosaccharides; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Wistar; Recurrence; Stents; Thrombosis | 2013 |
Cross-modal reorganization of cortical afferents to dorsal auditory cortex following early- and late-onset deafness.
Topics: Afferent Pathways; Age of Onset; Animals; Animals, Newborn; Auditory Cortex; Biotin; Cats; Deafness; Dextrans; Disease Models, Animal; Functional Laterality; Neurofilament Proteins; Neuronal Plasticity; Neurons; Photic Stimulation; Visual Cortex | 2014 |
Inhibitory effects of topical cyclosporine A 0.05% on immune-mediated corneal neovascularization in rabbits.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Apoptosis; Arthus Reaction; Bevacizumab; Biotin; Corneal Neovascularization; Cyclosporine; Deoxyuracil Nucleotides; Dexamethasone; Disease Models, Animal; Glucocorticoids; Immunoenzyme Techniques; Immunosuppressive Agents; In Situ Nick-End Labeling; Ophthalmic Solutions; Rabbits; Serum Albumin, Bovine | 2013 |
Biotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: clues for the pathogenesis in the human inherited disorder.
Topics: Animals; Biotin; Biotinidase Deficiency; Blood Glucose; Body Weight; Carbon; Carnitine; Diet; Disease Models, Animal; Energy Metabolism; Gene Expression; Humans; Liver; Mice; Mice, Knockout; RNA, Messenger | 2013 |
Histoplasma capsulatum depends on de novo vitamin biosynthesis for intraphagosomal proliferation.
Topics: Animals; Biotin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Histoplasma; Histoplasmosis; Macrophages; Mice; Mice, Inbred C57BL; Pantothenic Acid; Phagosomes; Riboflavin; Virulence | 2014 |
Sprouting of brainstem-spinal tracts in response to unilateral motor cortex stroke in mice.
Topics: Animals; Biotin; Brain Stem; Dextrans; Disease Models, Animal; Female; Fluorescent Dyes; Functional Laterality; Locomotion; Mice; Mice, Inbred C57BL; Motor Activity; Motor Cortex; Muscle Strength; Neural Pathways; Psychomotor Performance; Rotarod Performance Test; Spinal Cord; Stroke; Time Factors | 2014 |
Characterization and functional analysis of cellular immunity in mice with biotinidase deficiency.
Topics: Animals; Biotin; Biotinidase; Biotinidase Deficiency; CD4-Positive T-Lymphocytes; Disease Models, Animal; Immunity, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Spleen; Thymus Gland | 2014 |
pH-responsive polymer-liposomes for intracellular drug delivery and tumor extracellular matrix switched-on targeted cancer therapy.
Topics: Acrylamides; Animals; Antineoplastic Agents; Biotin; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Extracellular Matrix; Female; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polyethylene Glycols; Polymers; Tissue Distribution | 2014 |
A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury.
Topics: Animals; Antigens, Neoplasm; Biotin; Dextrans; Disease Models, Animal; Embryo, Mammalian; Female; Green Fluorescent Proteins; Hindlimb; Humans; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Neural Stem Cells; Pregnancy; Rats; Rats, Inbred F344; Rats, Transgenic; Spinal Cord; Spinal Cord Injuries; Time Factors; Urinary Bladder Diseases | 2014 |
Reorganization of supramammillary-hippocampal pathways in the rat pilocarpine model of temporal lobe epilepsy: evidence for axon terminal sprouting.
Topics: Animals; Biotin; Dextrans; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Hypothalamus, Posterior; Male; Muscarinic Agonists; Neural Pathways; Phosphopyruvate Hydratase; Pilocarpine; Presynaptic Terminals; Rabies virus; Rats; Rats, Wistar; Vesicular Glutamate Transport Protein 2 | 2015 |
Forced limb-use enhances brain plasticity through the cAMP/PKA/CREB signal transduction pathway after stroke in adult rats.
Topics: Animals; Biotin; Brain; CREB-Binding Protein; Cyclic AMP; Dextrans; Disease Models, Animal; Disks Large Homolog 4 Protein; Endothelin-1; Extremities; Intracellular Signaling Peptides and Proteins; Isoquinolines; Locomotion; Male; Membrane Proteins; Neuronal Plasticity; Protein Kinase C-alpha; Protein Kinase Inhibitors; Rats; Rats, Wistar; Restraint, Physical; Stroke; Stroke Rehabilitation; Sulfonamides; Synaptophysin | 2014 |
Beneficial effects of gfap/vimentin reactive astrocytes for axonal remodeling and motor behavioral recovery in mice after stroke.
Topics: Animals; Axons; Biotin; Brain Infarction; Calcium-Binding Proteins; Dextrans; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Movement Disorders; Nerve Regeneration; Nerve Tissue Proteins; Pyramidal Tracts; Recovery of Function; Stroke; Thrombosis; Versicans; Vimentin | 2014 |
Role of CSPG receptor LAR phosphatase in restricting axon regeneration after CNS injury.
Topics: Animals; Benzofurans; Biotin; Brain; Dextrans; Disease Models, Animal; Female; Gene Expression Regulation; Mice; Mice, Knockout; Motor Activity; Mutation; Nerve Regeneration; Pyramidal Tracts; Quinolines; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Recovery of Function; Serotonin; Spinal Cord Injuries; Time Factors | 2015 |
Amplified somatosensory and visual cortical projections to a core auditory area, the anterior auditory field, following early- and late-onset deafness.
Topics: Acoustic Stimulation; Afferent Pathways; Animals; Biotin; Cats; Deafness; Dextrans; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Male; Neurofilament Proteins; Sensation; Somatosensory Cortex; Time Factors; Visual Cortex | 2015 |
Schwann cells generated from neonatal skin-derived precursors or neonatal peripheral nerve improve functional recovery after acute transplantation into the partially injured cervical spinal cord of the rat.
Topics: Animals; Animals, Newborn; Biotin; Cell Differentiation; Cells, Cultured; Cervical Cord; Dextrans; Disease Models, Animal; Forelimb; Green Fluorescent Proteins; Motor Activity; Nerve Tissue Proteins; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Recovery of Function; Schwann Cells; Skin; Spinal Cord Injuries; Stromal Cells | 2015 |
Salmonella infection inhibits intestinal biotin transport: cellular and molecular mechanisms.
Topics: Animals; Biological Transport; Biotin; Caco-2 Cells; Disease Models, Animal; Host-Pathogen Interactions; Humans; Inflammation Mediators; Interferon-gamma; Intestinal Mucosa; Intestines; Mice; NF-kappa B; Promoter Regions, Genetic; Salmonella Infections, Animal; Salmonella typhimurium; Signal Transduction; Symporters; Transfection; Tumor Necrosis Factor-alpha | 2015 |
The Atypical Occurrence of Two Biotin Protein Ligases in Francisella novicida Is Due to Distinct Roles in Virulence and Biotin Metabolism.
Topics: Animals; Bacterial Proteins; Biotin; Carbon-Nitrogen Ligases; Colony Count, Microbial; Disease Models, Animal; Francisella; Genetic Complementation Test; Gram-Negative Bacterial Infections; Macrophages; Mice; Skin; Virulence; Virulence Factors | 2015 |
Compensatory projections of primary sensory fibers in lumbar spinal cord after neonatal thoracic spinal transection in rats.
Topics: Animals; Animals, Newborn; Axons; Biotin; Dextrans; Disease Models, Animal; Ganglia, Spinal; Gray Matter; Lumbar Vertebrae; Neuroanatomical Tract-Tracing Techniques; Neuronal Plasticity; Neuronal Tract-Tracers; Rats, Wistar; Sensory Receptor Cells; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae | 2015 |
Comprehensive Corticospinal Labeling with mu-crystallin Transgene Reveals Axon Regeneration after Spinal Cord Trauma in ngr1-/- Mice.
Topics: Amidines; Analysis of Variance; Animals; Axons; Biotin; Crystallins; Dextrans; Disease Models, Animal; Functional Laterality; Gene Expression Regulation; Glial Fibrillary Acidic Protein; GPI-Linked Proteins; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; mu-Crystallins; Myelin Proteins; Nerve Regeneration; Nogo Receptor 1; Pyramidal Tracts; Receptors, Cell Surface; Recovery of Function; Spinal Cord Injuries | 2015 |
Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS.
Topics: Animals; Axons; Biotin; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Male; Mutation; Myelin Basic Protein; Neurons; Phosphorylation; Protein Phosphatase 2; Quinazolines; Rats; Rats, Sprague-Dawley; Recovery of Function; Sphingosine; Spinal Cord Injuries; Tyrphostins | 2015 |
Combined motor cortex and spinal cord neuromodulation promotes corticospinal system functional and structural plasticity and motor function after injury.
Topics: Animals; Axons; Biotin; Dextrans; Disease Models, Animal; Electric Stimulation Therapy; Electrodes, Implanted; Electromyography; Evoked Potentials, Motor; Female; Forelimb; Functional Laterality; Locomotion; Motor Cortex; Neuronal Plasticity; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Wakefulness | 2016 |
SPECT/NIRF Dual Modality Imaging for Detection of Intraperitoneal Colon Tumor with an Avidin/Biotin Pretargeting System.
Topics: Animals; Avidin; Biotin; Cell Line, Tumor; Cell Tracking; Colonic Neoplasms; Contrast Media; Disease Models, Animal; Heterografts; Humans; Mice; Molecular Probes; Spectroscopy, Near-Infrared; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2016 |
Causal Link between the Cortico-Rubral Pathway and Functional Recovery through Forced Impaired Limb Use in Rats with Stroke.
Topics: Animals; Biotin; Cerebral Hemorrhage; Deep Brain Stimulation; Dextrans; Disease Models, Animal; Doxycycline; Forelimb; Functional Laterality; GABA-A Receptor Agonists; Internal Capsule; Male; Motor Cortex; Motor Skills; Movement Disorders; Muscimol; Neural Pathways; Rats; Rats, Wistar; Recovery of Function; Red Nucleus | 2016 |
RGD-Targeted Ultrasound Contrast Agent for Longitudinal Assessment of Hep-2 Tumor Angiogenesis In Vivo.
Topics: Acoustics; Animals; Avidin; Binding, Competitive; Biotin; Cell Adhesion; Cell Line; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Endothelial Cells; Female; Humans; Integrin alphaVbeta3; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microbubbles; Microscopy, Fluorescence; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Protein Binding; Ultrasonography; Video Recording | 2016 |
Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism.
Topics: Acetyl-CoA Carboxylase; Animals; ARNTL Transcription Factors; Biotin; Biotinylation; Carbon-Carbon Ligases; Carbon-Carbon Lyases; Chronobiology Disorders; Circadian Clocks; CLOCK Proteins; Disease Models, Animal; Energy Metabolism; Genetic Predisposition to Disease; Heart Diseases; Liver; Male; Methylmalonyl-CoA Decarboxylase; Mice, Inbred C57BL; Mice, Knockout; Mutation; Myocytes, Cardiac; Phenotype; Protein Processing, Post-Translational; Pyruvate Carboxylase; Symporters; Time Factors | 2016 |
Remodeling of Dendritic Spines in the Avian Vocal Motor Cortex Following Deafening Depends on the Basal Ganglia Circuit.
Topics: Analysis of Variance; Animals; Auditory Pathways; Basal Ganglia; Biotin; Deafness; Dendritic Spines; Dextrans; Disease Models, Animal; Electrolysis; Finches; High Vocal Center; Male; Microscopy, Confocal; Microscopy, Electron, Transmission; Motor Cortex; Synapses; Vocalization, Animal | 2017 |
Conditional Sox9 ablation improves locomotor recovery after spinal cord injury by increasing reactive sprouting.
Topics: Animals; Axons; Biotin; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Doxycycline; Edema; Enzyme Inhibitors; Humans; Locomotion; Mice; Nerve Tissue Proteins; Receptors, Estrogen; Recovery of Function; SOX9 Transcription Factor; Spinal Cord Injuries; Stilbamidines; Synaptophysin; Time Factors; Up-Regulation; Vesicular Glutamate Transport Protein 1 | 2016 |
Plasticity of lumbosacral propriospinal neurons is associated with the development of autonomic dysreflexia after thoracic spinal cord transection.
Topics: Afferent Pathways; Animals; Antibodies; Autonomic Dysreflexia; Biotin; Choline O-Acetyltransferase; Dextrans; Disease Models, Animal; Enkephalins; Female; gamma-Aminobutyric Acid; Glutamic Acid; Lumbosacral Region; Nerve Fibers; Neuronal Plasticity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries | 2008 |
Regenerative growth of corticospinal tract axons via the ventral column after spinal cord injury in mice.
Topics: Animals; Axonal Transport; Axons; Biotin; Cell Count; Dextrans; Disease Models, Animal; Functional Laterality; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Fibers, Myelinated; Nerve Regeneration; Neuronal Plasticity; Presynaptic Terminals; Pyramidal Tracts; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2008 |
Contralesional axonal remodeling of the corticospinal system in adult rats after stroke and bone marrow stromal cell treatment.
Topics: Animals; Axonal Transport; Biotin; Bone Marrow Transplantation; Brain Infarction; Brain Mapping; Dextrans; Disease Models, Animal; Electric Stimulation; Fluorescent Antibody Technique; Functional Laterality; Herpesvirus 1, Suid; Infarction, Middle Cerebral Artery; Male; Motor Cortex; Muscle, Skeletal; Nerve Regeneration; Neuronal Plasticity; Pyramidal Tracts; Rats; Rats, Wistar; Recovery of Function; Stroke; Stromal Cells | 2008 |
Diversity and fluctuation of spine morphology in CA1 pyramidal neurons after transient global ischemia.
Topics: Animals; Biotin; Dendritic Spines; Disease Models, Animal; Hippocampus; Ischemic Attack, Transient; Male; Pseudopodia; Pyramidal Cells; Rats; Rats, Wistar; Silver Staining; Time Factors | 2009 |
Axon sprouting in adult mouse spinal cord after motor cortex stroke.
Topics: Animals; Axons; Biotin; Dextrans; Disease Models, Animal; Mice; Motor Cortex; Neural Pathways; Spinal Cord; Stroke | 2009 |
Enhancement of inhibitory synaptic transmission in large aspiny neurons after transient cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Biophysics; Biotin; Calcium; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Ion Channel Gating; Ischemic Attack, Transient; Male; Membrane Potentials; Muscimol; Neurons; Ovulation Inhibition; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Time Factors | 2009 |
Experimental neuronal migration disorders following the administration of ibotenate in hamsters: the role of the subventricular zone in the development of cortical dysplasia.
Topics: Animals; Animals, Newborn; Apoptosis; Biotin; Cell Movement; Cerebral Cortex; Cerebral Ventricles; Cricetinae; Dextrans; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Ibotenic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Male; Malformations of Cortical Development; Neurons | 2009 |
Activity-based therapies to promote forelimb use after a cervical spinal cord injury.
Topics: Animals; Biotin; Cervical Vertebrae; Dextrans; Disease Models, Animal; Environment, Controlled; Exercise Therapy; Exploratory Behavior; Female; Forelimb; Gait Disorders, Neurologic; Movement Disorders; Neuronal Plasticity; Neuronal Tract-Tracers; Paralysis; Phosphodiesterase Inhibitors; Physical Conditioning, Animal; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Rolipram; Spinal Cord Injuries; Treatment Outcome | 2009 |
Bilateral cervical contusion spinal cord injury in rats.
Topics: Animals; Axotomy; Biotin; Cervical Vertebrae; Dextrans; Disease Models, Animal; Female; Forelimb; Functional Laterality; Growth Cones; Hand Strength; Lameness, Animal; Movement Disorders; Muscle Strength Dynamometer; Nerve Regeneration; Neurologic Examination; Neuronal Plasticity; Physical Stimulation; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Sensation Disorders; Spinal Cord Injuries; Staining and Labeling | 2009 |
Oligomers of beta-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Biotin; Disease Models, Animal; Humans; Immunohistochemistry; Islet Amyloid Polypeptide; Ligands; Male; Mice; Mice, Transgenic; Microscopy, Atomic Force; Molecular Weight; Peptide Fragments; Plaque, Amyloid; Thiazoles | 2010 |
Visual response properties of Y cells in the detached feline retina.
Topics: Animals; Biotin; Cats; Contrast Sensitivity; Disease Models, Animal; Electrophysiology; Female; Immunoenzyme Techniques; Isoquinolines; Male; Perceptual Disorders; Photic Stimulation; Retina; Retinal Detachment; Retinal Ganglion Cells; Sensory Thresholds; Visual Perception | 2010 |
Enhanced regenerative axon growth of multiple fibre populations in traumatic spinal cord injury following scar-suppressing treatment.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Axons; Biotin; Calcitonin Gene-Related Peptide; Cicatrix; Dextrans; Dicarboxylic Acids; Disease Models, Animal; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Iron Chelating Agents; Nerve Regeneration; Pyramidal Tracts; Rats; Rats, Wistar; Serotonin; Spinal Cord Injuries; Time Factors; Tyrosine 3-Monooxygenase | 2009 |
Functional recovery of stepping in rats after a complete neonatal spinal cord transection is not due to regrowth across the lesion site.
Topics: Age Factors; Amidines; Animals; Animals, Newborn; Axonal Transport; Biotin; Brain Stem; Dextrans; Disease Models, Animal; Efferent Pathways; Exercise Test; Female; Growth Cones; Herpesvirus 1, Suid; Lameness, Animal; Locomotion; Motor Cortex; Nerve Regeneration; Neuroanatomical Tract-Tracing Techniques; Neuronal Plasticity; Paralysis; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Staining and Labeling | 2010 |
Alterations of the cortico-cortical network in sensori-motor areas of dystrophin deficient mice.
Topics: Animals; Biotin; Cell Count; Cell Shape; Cerebral Cortex; Cognition Disorders; Dendrites; Dendritic Spines; Dextrans; Disease Models, Animal; Dystrophin; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Motor Cortex; Muscular Dystrophy, Duchenne; Nerve Net; Neuronal Tract-Tracers; Pyramidal Cells; Somatosensory Cortex; Staining and Labeling | 2010 |
Does age matter? Behavioral and neuro-anatomical effects of neonatal and adult basal forebrain cholinergic lesions.
Topics: Acetylcholine; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Antibodies, Monoclonal; Avoidance Learning; Behavior, Animal; Biotin; Brain Injuries; Choline O-Acetyltransferase; Dextrans; Discrimination Learning; Disease Models, Animal; Exploratory Behavior; gamma-Aminobutyric Acid; Learning Disabilities; Male; Maze Learning; Neurologic Examination; Neurons; Prosencephalon; Rats; Rats, Wistar; Ribosome Inactivating Proteins, Type 1; Saporins | 2010 |
MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma.
Topics: Analysis of Variance; Animals; Biotin; Cells, Cultured; Dextrans; Disease Models, Animal; Female; Functional Laterality; Ganglia, Spinal; GPI-Linked Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Nerve Tissue Proteins; Neurons; Nogo Proteins; Pyramidal Tracts; Receptors, Cell Surface; Receptors, Serotonin; Recovery of Function; Spinal Cord Injuries | 2010 |
Sprouting of corticospinal tract axons from the contralateral hemisphere into the denervated side of the spinal cord is associated with functional recovery in adult rat after traumatic brain injury and erythropoietin treatment.
Topics: Animals; Axons; Biotin; Brain Injuries; Dextrans; Disease Models, Animal; Erythropoietin; Functional Laterality; Hematocrit; Hindlimb; Male; Neurologic Examination; Psychomotor Performance; Pyramidal Tracts; Rats; Rats, Wistar; Recovery of Function; Spinal Cord; Statistics as Topic; Time Factors | 2010 |
Development and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorder.
Topics: Animals; Behavior, Animal; Biotin; Biotinidase; Biotinidase Deficiency; Body Weight; Diet; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurocutaneous Syndromes; Vitamin B Complex | 2011 |
Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium.
Topics: Acrylamides; Animals; Biotin; Coronary Circulation; Disease Models, Animal; Fibroblast Growth Factor 2; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; Inflammation; Injections; Male; Myocardial Infarction; Neovascularization, Physiologic; Rats; Rats, Inbred F344; Systole; Ultrasonography | 2011 |
Meningeal cells and glia establish a permissive environment for axon regeneration after spinal cord injury in newts.
Topics: Animals; Axons; Biotin; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Endothelial Cells; Extracellular Matrix Proteins; Meninges; Microscopy, Confocal; Microscopy, Electron, Transmission; Nerve Fibers, Myelinated; Nerve Regeneration; Nerve Tissue Proteins; Neuroglia; Recovery of Function; Salamandridae; Spinal Cord Injuries; Swimming; Time Factors; von Willebrand Factor | 2011 |
Caudal granular insular cortex is sufficient and necessary for the long-term maintenance of allodynic behavior in the rat attributable to mononeuropathy.
Topics: Analysis of Variance; Animals; Behavior, Animal; Biotin; Brain Mapping; Cerebral Cortex; Dextrans; Disease Models, Animal; Electrophysiology; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Functional Laterality; GABA-A Receptor Agonists; Hyperalgesia; Male; Muscimol; Pain Measurement; Pain Threshold; Physical Stimulation; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Sciatica; Time Factors | 2011 |
The antithrombotic activity of EP224283, a neutralizable dual factor Xa inhibitor/glycoprotein IIbIIIa antagonist, exceeds that of the coadministered parent compounds.
Topics: Animals; Biotin; Disease Models, Animal; Drug Combinations; Factor Xa; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligosaccharides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Thromboembolism; Tirofiban; Tyrosine | 2011 |
Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid leukemia xenograft model.
Topics: Animals; Antibodies; Biotin; Bismuth; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Immunologic; Dose-Response Relationship, Radiation; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Mice; Mice, Inbred BALB C; Organometallic Compounds; Radioimmunotherapy; Radioisotopes; Remission Induction; Streptavidin; Survival Rate; Xenograft Model Antitumor Assays | 2011 |
Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain.
Topics: Analysis of Variance; Animals; Axonal Transport; Biotin; Brain Infarction; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Callosum; Dendrites; Dextrans; Disease Models, Animal; Fetus; Gene Expression Regulation; Humans; Male; Nerve Tissue Proteins; Neural Stem Cells; Neuronal Plasticity; Psychomotor Performance; Rats; Rats, Nude; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Vibrissae | 2011 |
Transplantation of artificial neural construct partly improved spinal tissue repair and functional recovery in rats with spinal cord transection.
Topics: Animals; Animals, Newborn; Biotin; Cell Count; Cells, Cultured; Dextrans; Disease Models, Animal; Disks Large Homolog 4 Protein; Female; Intracellular Signaling Peptides and Proteins; Lactic Acid; Locomotion; Membrane Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Nerve Regeneration; Neural Stem Cells; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Stem Cell Transplantation; Transfection; Wound Healing | 2011 |
A filtered database search algorithm for endogenous serum protein carbonyl modifications in a mouse model of inflammation.
Topics: Algorithms; Animals; Avidin; Biotin; Blood Proteins; Cell Line, Tumor; Chromatography, Liquid; Databases, Protein; Disease Models, Animal; Inflammation; Lipid Peroxidation; Mice; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Software; Tandem Mass Spectrometry | 2011 |
[Content of chaperon Hsp70 in dopaminergic neurons of the black substance increases in proteasome dysfunstion].
Topics: Acetylcysteine; Aging; Animals; Bacterial Proteins; Biotin; Blotting, Western; Catheterization; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Microinjections; Microscopy, Confocal; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Wistar; Substantia Nigra; Tyrosine 3-Monooxygenase; Ubiquitin; Up-Regulation | 2011 |
Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.
Topics: Animals; Bacterial Proteins; Biotin; Chronic Disease; Disease Models, Animal; Drug Delivery Systems; Mice; Mutation; Mycobacterium tuberculosis; Transaminases; Tuberculosis | 2011 |
Chondroitinase ABC combined with neurotrophin NT-3 secretion and NR2D expression promotes axonal plasticity and functional recovery in rats with lateral hemisection of the spinal cord.
Topics: Analysis of Variance; Animals; Axons; beta-Galactosidase; Biotin; Cells, Cultured; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Fibroblasts; Gene Expression Regulation; Green Fluorescent Proteins; Hyperalgesia; Locomotion; Neuronal Plasticity; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Spinal Cord Injuries; Transfection | 2011 |
Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions.
Topics: Animals; Anti-Inflammatory Agents; Biotin; Brain Edema; Cerebral Cortex; Cerebral Infarction; Cytokines; Dextrans; Disease Models, Animal; Functional Laterality; Gene Expression Regulation; Hand Strength; Infarction, Middle Cerebral Artery; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neural Pathways; Neuronal Plasticity; Organometallic Compounds; Organophosphorus Compounds; Red Nucleus; Vascular Endothelial Growth Factor A | 2012 |
Administration of biotin prevents the development of insulin resistance in the skeletal muscles of Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Biotin; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Inbred OLETF | 2012 |
Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antibodies; Antibodies, Neutralizing; Behavioral Symptoms; Biotin; Cells, Cultured; Conditioning, Psychological; Dendritic Spines; Disease Models, Animal; Embryo, Mammalian; Epitopes; Fear; Gene Expression Regulation; Hippocampus; Humans; Mice; Mice, Transgenic; Microfilament Proteins; Microtubule-Associated Proteins; Mutation; Nerve Tissue Proteins; Neurons; Neuropeptides; Peptide Fragments; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Transport; Rats; Receptors, AMPA; Solubility; tau Proteins; Vesicular Glutamate Transport Protein 1 | 2012 |
Intraspinal rewiring of the corticospinal tract requires target-derived brain-derived neurotrophic factor and compensates lost function after brain injury.
Topics: Analysis of Variance; Animals; Biotin; Brain Injuries; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dextrans; Disease Models, Animal; Electromyography; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Forelimb; Functional Laterality; Gene Expression Regulation; Humans; Interneurons; Male; Mice; Mice, Inbred C57BL; Nerve Net; Nerve Regeneration; Psychomotor Performance; Pyramidal Tracts; Receptor, trkB; Recovery of Function; RNA, Small Interfering; Time Factors; Wheat Germ Agglutinins | 2012 |
Neuroprotection from stroke in the absence of MHCI or PirB.
Topics: Animals; Astrocytes; Biotin; Brain; Calcium-Binding Proteins; Dextrans; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Histocompatibility Antigens Class I; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Motor Activity; Motor Cortex; Organ Culture Techniques; Phosphopyruvate Hydratase; Pyramidal Tracts; Receptors, Immunologic; Recovery of Function; Signal Transduction; Time Factors | 2012 |
Extensive cell migration, axon regeneration, and improved function with polysialic acid-modified Schwann cells after spinal cord injury.
Topics: Animals; Bacterial Proteins; Biotin; Cell Count; Cell Movement; Dextrans; Disease Models, Animal; Exploratory Behavior; Female; Green Fluorescent Proteins; Linear Models; Luminescent Proteins; Nerve Regeneration; Psychomotor Performance; Rats; Rats, Inbred F344; Recovery of Function; Schwann Cells; Sciatic Nerve; Serotonin; Sialic Acids; Spinal Cord Injuries; Time Factors | 2012 |
Passive immunization with myelin basic protein activated T cells suppresses axonal dieback but does not promote axonal regeneration following spinal cord hemisection in adult rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antigens, CD; Biotin; Cell Proliferation; Cytokines; Dextrans; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Functional Laterality; Immunization, Passive; Locomotion; Myelin Basic Protein; Nerve Regeneration; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; T-Lymphocytes; Thymectomy | 2012 |
Synthetic biotinylated peptide compounds derived from Asp-hemolysin: novel potent inhibitors of platelet-activating factor.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biotin; Biotinylation; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Fungal Proteins; Hemolysin Proteins; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Peptide Fragments; Peptides; Platelet Activating Factor; Rats; Rats, Wistar | 2012 |
Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice.
Topics: Age Factors; Animals; Animals, Newborn; Anisotropy; Antigens, Neoplasm; Axons; Biotin; Brain Ischemia; Cerebral Cortex; Dextrans; Diffusion Tensor Imaging; Disease Models, Animal; DNA-Binding Proteins; Functional Laterality; Green Fluorescent Proteins; Luminescent Proteins; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Basic Protein; Neural Pathways; Nuclear Proteins; Psychomotor Performance; Recovery of Function; Red Fluorescent Protein; Time Factors; Ubiquitin-Protein Ligases | 2012 |
RNA interference against repulsive guidance molecule A improves axon sprout and neural function recovery of rats after MCAO/reperfusion.
Topics: Adenoviridae; Analysis of Variance; Animals; Axons; Biotin; Brain Infarction; Cerebral Cortex; Dextrans; Disease Models, Animal; Extrapyramidal Tracts; Functional Laterality; Gait Disorders, Neurologic; Gene Expression Regulation; GPI-Linked Proteins; Green Fluorescent Proteins; Hippocampus; Humans; Infarction, Middle Cerebral Artery; Interleukin-1beta; Laser-Doppler Flowmetry; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Regional Blood Flow; Reperfusion; RNA Interference; RNA, Messenger; Stereotaxic Techniques; Tetrazolium Salts; Time Factors | 2012 |
S-nitrosylated protein disulfide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Biotin; Cell Line, Tumor; Cysteine; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Transgenic; Mutation; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Disulfide-Isomerases; Protein Folding; S-Nitrosothiols; Spinal Cord; Subcellular Fractions; Superoxide Dismutase; Up-Regulation | 2013 |
SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI).
Topics: Animals; Animals, Newborn; Astrocytes; Biotin; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glucose; Hypoxia; Immunoprecipitation; Ischemia; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Disulfide-Isomerases; Rats; Rats, Wistar; Reperfusion Injury; Subcellular Fractions; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitin; Up-Regulation | 2012 |
Efferent projections of neuropeptide Y-expressing neurons of the dorsomedial hypothalamus in chronic hyperphagic models.
Topics: Age Factors; Animals; Animals, Newborn; Biotin; Chronic Disease; Dextrans; Disease Models, Animal; Efferent Pathways; Female; Gonadotropin-Releasing Hormone; Hyperphagia; Hypothalamic Hormones; Hypothalamus; Intracellular Signaling Peptides and Proteins; Lactic Acid; Male; Melanins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neuropeptide Y; Neuropeptides; Obesity; Orexins; Peptide Fragments; Pituitary Hormones; Pregnancy; Rats; Rats, Wistar; Tryptophan Hydroxylase | 2013 |
Effects of treating traumatic brain injury with collagen scaffolds and human bone marrow stromal cells on sprouting of corticospinal tract axons into the denervated side of the spinal cord.
Topics: Animals; Axons; Biotin; Brain Injuries; Collagen; Dextrans; Disease Models, Animal; Gait; Graft Survival; Growth Cones; Male; Maze Learning; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nerve Regeneration; Neuronal Plasticity; Pyramidal Tracts; Random Allocation; Rats; Rats, Wistar; Recovery of Function; Tissue Scaffolds | 2013 |
Elevated intraocular pressure causes inner retinal dysfunction before cell loss in a mouse model of experimental glaucoma.
Topics: Animals; Axial Length, Eye; Biomarkers; Biotin; Cell Count; Cell Death; Dark Adaptation; Disease Models, Animal; Electroretinography; Female; Fluorescent Antibody Technique, Indirect; Immunohistochemistry; Intraocular Pressure; Mice; Mice, Inbred C57BL; Ocular Hypertension; Retinal Diseases; Retinal Ganglion Cells; Tonometry, Ocular | 2013 |
Corticospinal sprouting occurs selectively following dorsal rhizotomy in the macaque monkey.
Topics: Action Potentials; Animals; Biotin; Dextrans; Disease Models, Animal; Functional Laterality; Isoquinolines; Macaca fascicularis; Male; Motor Cortex; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Pyramidal Tracts; Rhizotomy; Somatosensory Cortex; Spinal Cord Injuries; Spinal Nerve Roots; Spinal Nerves | 2013 |
Axonal and dendritic changes are associated with diabetic encephalopathy in rats: an important risk factor for Alzheimer's disease.
Topics: Animals; Axons; Biotin; Cognition Disorders; Dendrites; Dextrans; Diabetes Mellitus, Experimental; Disease Models, Animal; Electric Stimulation; Male; Maze Learning; Neurons; Rats; Rats, Sprague-Dawley; Risk Factors; tau Proteins; Time Factors | 2013 |
Neuroprotection by selective nitric oxide synthase inhibition at 24 hours after perinatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apoptosis; Biotin; Brain; Brain Edema; Caspase 3; Caspases; Disease Models, Animal; Energy Metabolism; Enzyme Inhibitors; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Nitric Oxide Synthase; Reperfusion Injury; Survival Rate; Swine; Treatment Outcome; Tyrosine | 2002 |
Altered red cell turnover in diabetic mice.
Topics: Animals; Biotin; Diabetes Mellitus, Type 2; Disease Models, Animal; Erythrocyte Aging; Erythrocytes, Abnormal; Female; Flow Cytometry; Hematologic Tests; Homozygote; Mice; Mice, Inbred C57BL; Phosphatidylserines | 2002 |
Application of purging biotinylated liposomes from plasma to elucidate influx and efflux processes associated with accumulation of liposomes in solid tumors.
Topics: Animals; Avidin; Biotin; Colonic Neoplasms; Disease Models, Animal; Female; Liposomes; Mice; Phosphatidylcholines; Time Factors; Tissue Distribution | 2003 |
Effects of early ethanol exposure on dendrite growth of cortical pyramidal neurons: inferences from a computational model.
Topics: Age Factors; Alcohol-Induced Disorders, Nervous System; Animals; Animals, Newborn; Biotin; Cell Differentiation; Cell Size; Cerebral Cortex; Dendrites; Dextrans; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Intellectual Disability; Models, Neurological; Pregnancy; Pyramidal Cells; Rats; Rats, Wistar | 2003 |
Redox state of near infrared spectroscopy-measured cytochrome aa(3) correlates with delayed cerebral energy failure following perinatal hypoxia-ischaemia in the newborn pig.
Topics: Allopurinol; Animals; Animals, Newborn; Biotin; Brain; Cell Survival; Deferoxamine; Disease Models, Animal; Disease Progression; Electron Transport Complex IV; Energy Metabolism; Free Radical Scavengers; Hypoxia-Ischemia, Brain; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Neurons; Neuroprotective Agents; Oxidation-Reduction; Phosphates; Phosphocreatine; Predictive Value of Tests; Spectroscopy, Near-Infrared; Swine | 2004 |
Prefrontal lesion reverses abnormal mesoaccumbens response in an animal model of schizophrenia.
Topics: Animals; Animals, Newborn; Behavior, Animal; Biotin; Disease Models, Animal; Dopamine; Electric Stimulation; Electrophysiology; Female; Hippocampus; Male; Membrane Potentials; Neurons; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia | 2004 |
Strategies for improving the anti-neoplastic activity of TNF by tumor targeting.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Binding Sites; Biotin; CD13 Antigens; Disease Models, Animal; Ligands; Mice; Neoplasms; Neoplasms, Experimental; Recombinant Fusion Proteins; Tumor Necrosis Factor-alpha | 2004 |
Nitrosylation precedes caspase-3 activation and translocation of apoptosis-inducing factor in neonatal rat cerebral hypoxia-ischaemia.
Topics: Animals; Animals, Newborn; Apoptosis Inducing Factor; Biomarkers; Biotin; Caspase 3; Caspases; Cell Count; Disease Models, Animal; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Female; Flavoproteins; Hypoxia-Ischemia, Brain; Male; Membrane Proteins; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Protein Transport; Rats; Rats, Wistar; Tyrosine | 2004 |
Rubrospinal neurons fail to respond to brain-derived neurotrophic factor applied to the spinal cord injury site 2 months after cervical axotomy.
Topics: Animals; Axotomy; Biotin; Brain Stem; Brain-Derived Neurotrophic Factor; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Dyes; GAP-43 Protein; Gene Expression; Immunohistochemistry; In Situ Hybridization; Male; Nerve Regeneration; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Receptor, trkB; Red Nucleus; Spinal Cord Injuries; Stilbamidines; Time Factors; Tubulin | 2004 |
Neonatal hypoxia suppresses oligodendrocyte Nogo-A and increases axonal sprouting in a rodent model for human prematurity.
Topics: Age Factors; Animals; Animals, Newborn; Axons; Behavior, Animal; Biotin; Central Nervous System; Dextrans; Disease Models, Animal; Exploratory Behavior; Humans; Hypoxia, Brain; Immunoblotting; Immunohistochemistry; Infant, Newborn; Infant, Premature; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Myelin Proteins; Myelin-Associated Glycoprotein; Nogo Proteins; Oligodendroglia; Receptors, Cell Surface; Time Factors | 2004 |
Quantitative assessment of forelimb motor function after cervical spinal cord injury in rats: relationship to the corticospinal tract.
Topics: Animals; Biotin; Dextrans; Disability Evaluation; Disease Models, Animal; Female; Forelimb; Gait Disorders, Neurologic; Hand Strength; Motor Skills; Movement Disorders; Muscle, Skeletal; Neck Injuries; Neurologic Examination; Paresis; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Somatosensory Disorders; Spinal Cord; Spinal Cord Injuries | 2005 |
Delayed inhibition of Nogo-A does not alter injury-induced axonal sprouting but enhances recovery of cognitive function following experimental traumatic brain injury in rats.
Topics: Analysis of Variance; Animals; Antibodies; Axons; Behavior, Animal; Biotin; Brain Injuries; Cognition; Dextrans; Disease Models, Animal; Functional Laterality; Hippocampus; Male; Motor Activity; Myelin Proteins; Nogo Proteins; Rats; Rats, Sprague-Dawley; Reaction Time; Recovery of Function; Time Factors | 2005 |
Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury.
Topics: Analysis of Variance; Animals; Axons; Behavior, Animal; Biotin; Cells, Cultured; Chick Embryo; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Female; Ganglia, Spinal; GPI-Linked Proteins; Immunoglobulin G; Laminectomy; Methylprednisolone; Myelin Proteins; Myelin Sheath; Nerve Regeneration; Neurons; Nogo Receptor 1; Pyramidal Tracts; Rats; Rats, Long-Evans; Receptors, Cell Surface; Receptors, Peptide; Recombinant Proteins; Recovery of Function; Spinal Cord Injuries | 2005 |
Structure-function relations of parasol cells in the normal and glaucomatous primate retina.
Topics: Animals; Biotin; Cell Count; Dendrites; Disease Models, Animal; Female; Glaucoma; Intraocular Pressure; Macaca mulatta; Male; Membrane Potentials; Microelectrodes; Neurons; Optic Nerve Diseases; Retinal Ganglion Cells | 2005 |
Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury.
Topics: Actin Depolymerizing Factors; Amides; Analysis of Variance; Animals; Axons; Behavior, Animal; Biotin; Blotting, Western; Cholera Toxin; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Myosin-Light-Chain Phosphatase; Nerve Regeneration; Pain Measurement; Phosphorylation; Protein Serine-Threonine Kinases; Psychomotor Performance; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Recovery of Function; rho-Associated Kinases; Rotarod Performance Test; Spinal Cord Injuries | 2005 |
Determining maximal tolerable dose of the monoclonal antibody BR96 labeled with 90Y or 177Lu in rats: establishment of a syngeneic tumor model to evaluate means to improve radioimmunotherapy.
Topics: Animals; Antibodies, Monoclonal; Biotin; Body Weight; Brain; Chelating Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Heterocyclic Compounds, 1-Ring; Leukocytes; Lutetium; Maximum Tolerated Dose; Platelet Count; Radioimmunotherapy; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Rats; Time Factors; Yttrium Radioisotopes | 2005 |
GeneCalling: transcript profiling coupled to a gene database query.
Topics: Animals; Biotin; Computational Biology; Databases, Genetic; Disease Models, Animal; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation; Genetic Techniques; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Oligonucleotides; RNA; RNA, Messenger; Transcription, Genetic | 2006 |
The cell cycle-apoptosis connection revisited in the adult brain.
Topics: Animals; Apoptosis; Biotin; Brain; Bromodeoxyuridine; Cell Cycle; Disease Models, Animal; DNA; DNA Repair; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mitosis; Neurodegenerative Diseases; Neurons; Olfactory Bulb; S Phase; Thymidine; Time Factors | 2005 |
Avidin-biotin system pretargeting radioimmunoimaging and radioimmunotherapy and its application in mouse model of human colon carcinoma.
Topics: Animals; Antibodies, Monoclonal; Avidin; Biotin; Carcinoembryonic Antigen; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Radioimmunodetection; Radioimmunotherapy; Radioisotopes; Random Allocation; Samarium; Transplantation, Heterologous | 2005 |
Profound differences in spontaneous long-term functional recovery after defined spinal tract lesions in the rat.
Topics: Animals; Biotin; Denervation; Dextrans; Disability Evaluation; Disease Models, Animal; Efferent Pathways; Female; Gait Disorders, Neurologic; Growth Cones; Locomotion; Nerve Regeneration; Neuronal Plasticity; Pyramidal Tracts; Rats; Rats, Wistar; Recovery of Function; Red Nucleus; Spinal Cord; Spinal Cord Injuries; Time; Time Factors | 2006 |
Delayed treatment with Rho-kinase inhibitor does not enhance axonal regeneration or functional recovery after spinal cord injury in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Behavior, Animal; Biotin; Dextrans; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Nerve Regeneration; Protein Serine-Threonine Kinases; Pyramidal Tracts; Rats; Rats, Wistar; Recovery of Function; rho-Associated Kinases; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors | 2006 |
Degradation of chondroitin sulfate proteoglycans potentiates transplant-mediated axonal remodeling and functional recovery after spinal cord injury in adult rats.
Topics: Animals; Animals, Newborn; Axons; Behavior, Animal; Biotin; Cell Count; Cell Transplantation; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Dextrans; Diagnostic Imaging; Disease Models, Animal; Enzyme Activation; Female; Immunohistochemistry; Motor Activity; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Recovery of Function; Serotonin; Spinal Cord Injuries; Time Factors | 2006 |
Neutralization of the chemokine CXCL10 reduces apoptosis and increases axon sprouting after spinal cord injury.
Topics: Animals; Antibodies; Apoptosis; Biomechanical Phenomena; Biotin; Brain Stem; CD4-Positive T-Lymphocytes; Chemokine CXCL10; Chemokines, CXC; Dextrans; Disease Models, Animal; Female; Gene Expression Regulation; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Motor Activity; Oligonucleotide Array Sequence Analysis; Recovery of Function; Spinal Cord Injuries; Time Factors | 2006 |
Axonal plasticity is associated with motor recovery following amphetamine treatment combined with rehabilitation after brain injury in the adult rat.
Topics: Amphetamine; Animals; Axons; Biotin; Brain Injuries; Central Nervous System Stimulants; Dextrans; Disease Models, Animal; Efferent Pathways; Growth Cones; Male; Motor Cortex; Nerve Regeneration; Neuronal Plasticity; Paresis; Physical Therapy Modalities; Pyramidal Tracts; Rats; Rats, Long-Evans; Recovery of Function; Treatment Outcome | 2006 |
Changes in blood-brain barrier permeability to large and small molecules following traumatic brain injury in mice.
Topics: Animals; Biological Transport; Biotin; Blood Proteins; Blood-Brain Barrier; Brain Injuries; Capillary Permeability; Disease Models, Animal; Horseradish Peroxidase; Male; Mice; Mice, Inbred C57BL; Time Factors | 2007 |
The role of spinal tissue scarring in the pathogenesis of progressive post-traumatic myelomalacia.
Topics: Animals; Axons; Biotin; Cicatrix; Dextrans; Disease Models, Animal; Epidural Space; Female; Hyperalgesia; Motor Activity; Psychomotor Performance; Pyramidal Tracts; Rats; Rats, Inbred F344; Spinal Cord; Spinal Cord Diseases; Statistics, Nonparametric; Time Factors | 2006 |
The connexin31 F137L mutant mouse as a model for the human skin disease erythrokeratodermia variabilis (EKV).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Biotin; Connexin 26; Connexin 43; Connexins; Disease Models, Animal; DNA Primers; HeLa Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Molecular Sequence Data; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Skin Diseases, Genetic; Transfection | 2007 |
Axonal regeneration and development of de novo axons from distal dendrites of adult feline commissural interneurons after a proximal axotomy.
Topics: Age Factors; Animals; Axotomy; Biomarkers; Biotin; Cats; Dendrites; Disease Models, Animal; Functional Laterality; GAP-43 Protein; Growth Cones; Immunohistochemistry; Interneurons; Microtubule-Associated Proteins; Nerve Regeneration; Neuronal Plasticity; Presynaptic Terminals; Recovery of Function; Reproducibility of Results; Spinal Cord Injuries | 2007 |
Spinal pathways involved in the control of forelimb motor function in rats.
Topics: Adaptation, Physiological; Animals; Biotin; Dextrans; Disease Models, Animal; Efferent Pathways; Female; Forelimb; Glial Fibrillary Acidic Protein; Gliosis; Hand Strength; Motor Skills; Movement; Movement Disorders; Muscle Strength; Muscle Strength Dynamometer; Muscle Weakness; Muscle, Skeletal; Neuronal Plasticity; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Wallerian Degeneration | 2007 |
Effects of wild-type and mutant human amyloid precursor protein on cortical afferent network.
Topics: Acetylcholine; Afferent Pathways; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Basal Nucleus of Meynert; Biomarkers; Biotin; Cerebral Cortex; Cholinergic Fibers; Dextrans; Disease Models, Animal; Enzymes; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Inhibitory Postsynaptic Potentials; Mice; Mice, Transgenic; Mutation; Nerve Net; Norepinephrine; Presynaptic Terminals; Pyramidal Cells; Synaptic Transmission | 2007 |
Gender-dependent pathways of hypoxia-ischemia-induced cell death and neuroprotection in the immature P3 rat.
Topics: Aging; Animals; Animals, Newborn; Biotin; Birth Injuries; Brain; Cell Death; Cytochromes c; Cytoprotection; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Hypoxia-Ischemia, Brain; Male; Mitochondria; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Sex Characteristics; Time; Treatment Outcome | 2007 |
Audition differently activates the visual system in neonatally enucleated mice compared with anophthalmic mutants.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Animals, Newborn; Anophthalmos; Auditory Cortex; Auditory Perception; Biotin; Blindness; Cell Count; Dextrans; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Proto-Oncogene Proteins c-fos; Visual Pathways | 2007 |
Postnatal electrical and morphological abnormalities in lumbar motoneurons from transgenic mouse models of amyotrophic lateral sclerosis.
Topics: Action Potentials; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Biotin; Cell Differentiation; Cell Polarity; Cell Shape; Dendrites; Disease Models, Animal; Humans; Lumbosacral Region; Mice; Mice, Transgenic; Motor Neurons; Nerve Degeneration; Organ Culture Techniques; Riluzole; Sodium Channel Blockers; Sodium Channels; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
Spatiotemporal loss of K+ transport proteins in the developing cochlear lateral wall of guinea pigs with hereditary deafness.
Topics: Animals; Biotin; Claudin-1; Cochlea; Connexin 26; Connexins; Deafness; Disease Models, Animal; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Guinea Pigs; KCNQ1 Potassium Channel; Membrane Proteins; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pregnancy; Sodium-Potassium-Chloride Symporters; Stria Vascularis | 2008 |
Therapeutic time window for the application of chondroitinase ABC after spinal cord injury.
Topics: Animals; Behavior, Animal; Biotin; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Dextrans; Disease Models, Animal; Feeding Behavior; Forelimb; Gait; Glial Fibrillary Acidic Protein; Injections, Intraventricular; Motor Skills; Protein Kinase C; Pyramidal Tracts; Rats; Spinal Cord Injuries; Time Factors | 2008 |
Immune activation is required for NT-3-induced axonal plasticity in chronic spinal cord injury.
Topics: Analysis of Variance; Animals; Antigens, CD; Biotin; Chronic Disease; Dextrans; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Regulation; Genetic Vectors; Immunosuppressive Agents; Lipopolysaccharides; Microglia; Motor Neurons; Neuronal Plasticity; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors | 2008 |
[A new method for screening binding proteins that interact with the promoter of lipopolysaccharide inducible genes and its application].
Topics: Animals; Biotin; Disease Models, Animal; DNA; DNA Probes; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Promoter Regions, Genetic; Shock, Septic; Streptavidin | 2008 |
A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice.
Topics: Analysis of Variance; Animals; Axons; Behavior, Animal; Biomechanical Phenomena; Biotin; Dextrans; Disease Models, Animal; Female; GPI-Linked Proteins; Mice; Mice, Inbred C57BL; Motor Activity; Myelin Proteins; Nogo Receptor 1; Peptide Fragments; Psychomotor Performance; Receptors, Cell Surface; Recovery of Function; Regeneration; Serotonin; Spinal Cord Injuries; Time Factors | 2008 |
Identity of myelinated cutaneous sensory neurons projecting to nocireceptive laminae following nerve injury in adult mice.
Topics: Action Potentials; Animals; Axotomy; Biotin; Calcitonin Gene-Related Peptide; Cholera Toxin; Disease Models, Animal; Ganglia, Spinal; Male; Mice; Nerve Fibers, Myelinated; Neurons, Afferent; Nociceptors; Peripheral Nervous System Diseases; Protein Transport; Skin; Substantia Gelatinosa | 2008 |
Interactions between cardiomyocytes and lymphocytes in tissue culture: an in vitro model of inflammatory heart disease.
Topics: Animals; B-Lymphocytes; Biotin; Cell Adhesion; Cell Communication; Cell Movement; Cells, Cultured; Colorimetry; Coronary Disease; Culture Techniques; Disease Models, Animal; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; Lymphocytes; Mice; Mice, Inbred CBA; Myocarditis; Myocardium; Pregnancy; T-Lymphocytes | 1994 |
Eosinophil and foam cell accumulation in lungs of Sprague-Dawley rats fed purified, biotin-deficient diets.
Topics: Animals; Biotin; Body Weight; Diet; Disease Models, Animal; Eosinophils; Foam Cells; Lung; Male; Microscopy, Electron; Ovalbumin; Pulmonary Eosinophilia; Rats; Rats, Sprague-Dawley; Staining and Labeling | 1995 |
The metabolite profile of radioisotope-labeled biotin in rats indicates that rat biotin metabolism is similar to that in humans.
Topics: Animals; Biotin; Chromatography, High Pressure Liquid; Disease Models, Animal; Humans; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Species Specificity | 1996 |
Alterations of neuronal fibers after epileptic activity induced by pentylenetetrazole: fine structure investigated by calcium cytochemistry and neurobiotin labeling (buccal ganglia, Helix pomatia).
Topics: Animals; Biotin; Calcium; Cheek; Dendrites; Disease Models, Animal; Electrophysiology; Epilepsy; Ganglia, Invertebrate; Helix, Snails; Histocytochemistry; Microscopy, Electron; Nerve Fibers; Neurons; Pentylenetetrazole | 1996 |
Immuno-capillary electrophoresis for the characterization of a monoclonal antibody against DNA.
Topics: Animals; Antibodies, Antinuclear; Antibodies, Monoclonal; Bacterial Proteins; Biotin; Disease Models, Animal; DNA Primers; DNA, Antisense; Electrophoresis, Capillary; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Osmolar Concentration; Streptavidin | 1996 |
A high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus.
Topics: Animals; Biotin; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Secretion; Male; Rats; Rats, Inbred Strains | 1996 |
Biotin administration improves the impaired glucose tolerance of streptozotocin-induced diabetic Wistar rats.
Topics: Animals; Biotin; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucokinase; Glucose Tolerance Test; Hexokinase; Insulin; Insulin Secretion; Kidney; Liver; Male; Organ Size; Pancreas; Rats; Rats, Wistar; Spleen; Streptozocin | 1997 |
C3H mice have larger spleens, lower platelet counts, and shorter platelet lifespans than C57BL mice: an animal model for the study of hypersplenism.
Topics: Animals; Biotin; Blood Platelets; Cell Survival; Disease Models, Animal; Female; Hypersplenism; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Organ Size; Platelet Count; Splenectomy; Thrombocytopenia | 1997 |
Time course of apoptosis in collagen-induced arthritis.
Topics: Animals; Apoptosis; Arthritis; Biotin; Collagen; Deoxyuracil Nucleotides; Disease Models, Animal; DNA Nucleotidylexotransferase; Injections, Subcutaneous; Male; Mice; Mice, Inbred DBA; Synovial Membrane; Time Factors | 1998 |
Apoptosis and expression of Bax protein and Fas antigen in glomeruli of a remnant-kidney model.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Biotin; Cell Count; Cell Division; Creatinine; Deoxyuracil Nucleotides; Disease Models, Animal; DNA Fragmentation; fas Receptor; Kidney Diseases; Kidney Glomerulus; Male; Nephrectomy; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Staining and Labeling | 1998 |
Aspirin prevents tumors in a murine model of familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; beta Catenin; Biotin; Cadherins; Cell Division; Cytoskeletal Proteins; Deoxyuracil Nucleotides; Disease Models, Animal; DNA Fragmentation; Female; Germ-Line Mutation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Staining and Labeling; Trans-Activators | 1998 |
Specific targeting of activated endothelium in rat adjuvant arthritis with a 99mTc-radiolabeled E-selectin-binding peptide.
Topics: Amino Acid Sequence; Animals; Antigens, Bacterial; Arthritis, Experimental; Biotin; Cells, Cultured; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Mice; Mice, Inbred MRL lpr; Molecular Sequence Data; Mycoplasma; Osteoarthritis; Peptide Fragments; Protein Binding; Radionuclide Imaging; Rats; Rats, Inbred Lew; Synovial Membrane; Technetium; Umbilical Veins | 1999 |
Organization of cortico-cortical associative projections in a rat model of microgyria.
Topics: Animals; Animals, Newborn; Axonal Transport; Biotin; Brain; Cerebral Cortex; Dextrans; Disease Models, Animal; Fluorescent Dyes; Frontal Lobe; N-Methylaspartate; Neural Pathways; Neurons; Rats; Rats, Wistar | 2000 |
A novel anionic modification of N-glycans on mammalian endothelial cells is recognized by activated neutrophils and modulates acute inflammatory responses.
Topics: Acute Disease; Adjuvants, Immunologic; Amidohydrolases; Aminopyridines; Animals; Anions; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Binding Sites, Antibody; Biotin; Carboxylic Acids; Cattle; Cell Movement; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Epitopes; Female; Humans; Injections, Intravenous; Mice; Mice, Inbred BALB C; Monocytes; Neutrophil Activation; Neutrophils; Oligosaccharides; Organ Specificity; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Peritonitis | 2001 |
Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins.
Topics: Animals; Biotin; Brain Ischemia; Cell Survival; Cells, Cultured; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microinjections; Nerve Growth Factors; Neurites; Neurons; Neuroprotective Agents; Prostaglandin D2; Prostaglandins; Structure-Activity Relationship | 2001 |
The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Animals; Biotin; Calcium Channels; Calcium Channels, L-Type; Cerebellum; Codon, Terminator; COS Cells; Dendrites; Disease Models, Animal; DNA, Complementary; Electrophysiology; Fluorescent Dyes; Genotype; Immunohistochemistry; In Situ Hybridization; Isoquinolines; Kinetics; Mice; Models, Biological; Molecular Sequence Data; Mutation; Phenotype; Protein Structure, Tertiary; Purkinje Cells; Rats; RNA, Messenger; Time Factors; Transfection; Xenopus | 2002 |
Some biochemical observations on biotin deficiency in the rat as a model for human pyruvate carboxylase deficiency.
Topics: Amino Acids; Animals; Biotin; Brain; Carboxylic Acids; Disease Models, Animal; Fatty Acids; Female; Humans; Liver; Male; Maternal-Fetal Exchange; Organ Size; Pregnancy; Pyruvate Carboxylase; Pyruvate Carboxylase Deficiency Disease; Rats | 1979 |
Effect of chronic renal failure on intestinal transport of biotin in the rat.
Topics: Animals; Biological Transport; Biotin; Disease Models, Animal; Intestinal Mucosa; Kidney Failure, Chronic; Male; Rats; Rats, Inbred Strains | 1992 |
Rat as a potential model for hearing loss in biotinidase deficiency.
Topics: Amidohydrolases; Animals; Biotin; Biotinidase; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Genes, Recessive; Hair Cells, Auditory; Hearing Loss, Sensorineural; Male; Metabolism, Inborn Errors; Microscopy, Electron, Scanning; Organ of Corti; Rats; Rats, Inbred Strains | 1991 |
Stability and localization of biotin-labeled murine monoclonal antibody to human gastric cancer in normal mice and nude mice-human tumor models.
Topics: Adenocarcinoma, Scirrhous; Animals; Antibodies, Monoclonal; Biotin; Cell Line; Disease Models, Animal; Humans; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Stomach Neoplasms; Transplantation, Heterologous | 1990 |
Chronic ethanol feeding and acute ethanol exposure in vitro: effect on intestinal transport of biotin.
Topics: Alcoholism; Animals; Biological Transport; Biotin; Culture Techniques; Disease Models, Animal; Ethanol; Jejunum; Male; Rats; Rats, Inbred Strains | 1990 |
Studies on detection of Candida antigen in the sera of mice inoculated orally with Candida albicans.
Topics: Animals; Antigens, Fungal; Avidin; Biotin; Candida albicans; Candidiasis; Digestive System; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gastrointestinal Diseases; Intestine, Small; Leukocyte Count; Male; Mice; Predictive Value of Tests | 1988 |
Abnormal organic aciduria in biotin deficiency: the rat is similar to the human.
Topics: Animals; Biotin; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glycine; Male; Random Allocation; Rats; Rats, Inbred Strains; Valerates | 1988 |
[Biochemical mechanisms of steatosis as sequelae of "nucleotide imbalance"].
Topics: Acetates; Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Azaserine; Biotin; Carbon Isotopes; Cholesterol; Disease Models, Animal; Ethionine; Fatty Liver; Lipid Metabolism; Lipids; Nucleotides; Orotic Acid; Phospholipids; Pyrazoles; Pyrimidines; Rats; Triglycerides | 1970 |