biotin has been researched along with Disease Exacerbation in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Barbin, L; Couloume, L; Edan, G; Kerbrat, A; Laplaud, DA; Le Page, E; Le Port, D; Leray, E; Michel, L; Ory, S; Wiertlewski, S | 1 |
| Cao, Y; Chen, Y; Cheng, J; Chu, F; Ding, X; Du, S; Durojaye, OA; Gao, X; Li, Y; Liu, X; Shi, X; Song, X; Su, Z; Wang, D; Wang, F; Wang, J; Wang, T; Zeng, W | 1 |
| Arnold, D; Block, V; Comi, G; Cree, BAC; Cutter, G; Freedman, MS; Giovannoni, G; Hartung, HP; Kuhle, J; Lublin, FD; Munschauer, FE; Sedel, F; Wolinsky, JS | 1 |
| Amann, M; Barro, C; Collongues, N; de Seze, J; Kappos, L; Kuhle, J; Lamy, J; Meyer, N; Moreau, T; Parmar, K; Tsagkas, C; Wuerfel, J | 1 |
| Bernard, D; Mock, DM; Sedel, F; Tourbah, A | 1 |
| Bernard, D; Debruyne, D; Defer, GL; Mock, DM; Peyro Saint Paul, L | 1 |
| Brochet, B; Clanet, M; Clavelou, P; De Sèze, J; Debouverie, M; Defer, G; Edan, G; Gout, O; Labauge, P; Laplaud, DA; Lebrun-Frenay, C; Moreau, T; Papeix, C; Pelletier, J; Sedel, F; Tourbah, A; Vukusic, S | 1 |
| Béliveau, R; Gingras, D; Nyalendo, C; Sartelet, H | 1 |
| Chen, X; Cui, L; Guan, T; Kong, J; Li, C; Li, XM; Shang, H; Zhang, X | 1 |
| Omran, OM | 1 |
| Groenendaal, F; Peeters-Scholte, C; van Bel, F; van den Tweel, E | 1 |
| Kitayama, J; Konishi, T; Nagawa, H; Sasaki, S; Watanabe, T | 1 |
| Agnantis, NJ; Briasoulis, E; Charchanti, A; Damala, K; Ioachim, E; Karavasilis, V; Pavlidis, N; Tsanou, E | 1 |
| Bandiera, E; Bignotti, E; Calza, S; Donzelli, C; Falchetti, M; Odicino, FE; Pasinetti, B; Pecorelli, S; Ragnoli, M; Ravaggi, A; Romani, C; Santin, AD; Tassi, RA | 1 |
| de la Sierra García-Valdecasas, M; del Portal, LR; Delgado, C; Jiménez, LM; Macías, C; Pérez, M | 1 |
| Araújo, NS; da Costa, JE; de Souza, PE; Gomez, RS | 1 |
| Kien, CL; Tsao, CY | 1 |
2 review(s) available for biotin and Disease Exacerbation
| Article | Year |
|---|---|
Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis.
Topics: Animals; Biotin; Demyelinating Diseases; Disease Progression; Dose-Response Relationship, Drug; Humans; Hypoxia; Multiple Sclerosis; Vitamin B Complex | 2016 |
Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis.
Topics: Animals; Biological Availability; Biotin; Disease Progression; Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Randomized Controlled Trials as Topic; Vitamin B Complex | 2016 |
2 trial(s) available for biotin and Disease Exacerbation
| Article | Year |
|---|---|
Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial.
Topics: Adolescent; Adult; Aged; Biotin; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Outcome Assessment, Health Care; Severity of Illness Index; Vitamin B Complex; Walking Speed; Young Adult | 2020 |
MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.
Topics: Adult; Biotin; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Outcome Assessment, Health Care; Vitamin B Complex | 2016 |
13 other study(ies) available for biotin and Disease Exacerbation
| Article | Year |
|---|---|
High-dose biotin in progressive multiple sclerosis: A prospective study of 178 patients in routine clinical practice.
Topics: Adult; Biotin; Disability Evaluation; Disease Progression; Humans; Magnetic Resonance Imaging; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies | 2020 |
Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells.
Topics: Biotin; Carcinoma, Hepatocellular; Catalytic Domain; Cell Movement; Cytoskeletal Proteins; Disease Progression; HEK293 Cells; Hep G2 Cells; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Molecular Docking Simulation; Neoplasm Invasiveness; Neoplasm Metastasis; Pentacyclic Triterpenes; Phosphorylation; rho-Associated Kinases; Triterpenes; Wound Healing | 2020 |
Biomarkers of treatment response in patients with progressive multiple sclerosis treated with high-dose pharmaceutical-grade biotin (MD1003).
Topics: Bayes Theorem; Biomarkers; Biotin; Disability Evaluation; Disease Progression; Humans; Magnetic Resonance Imaging; Multiple Sclerosis | 2021 |
Inhibition of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation blocks tumor progression in mice.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Biotin; Caspases; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Matrix Metalloproteinase 14; Mice; Molecular Sequence Data; Peptides; Phosphorylation; Sarcoma, Experimental; Tyrosine; Xenograft Model Antitumor Assays | 2010 |
S-nitrosylated protein disulfide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Biotin; Cell Line, Tumor; Cysteine; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Transgenic; Mutation; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Disulfide-Isomerases; Protein Folding; S-Nitrosothiols; Spinal Cord; Subcellular Fractions; Superoxide Dismutase; Up-Regulation | 2013 |
CD10 and E-cad expression in urinary bladder urothelial and squamous cell carcinoma.
Topics: Adult; Aged; Biomarkers, Tumor; Biotin; Cadherins; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Disease Progression; Egypt; Female; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Staging; Neprilysin; Schistosomiasis; Streptavidin; Stromal Cells; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2012 |
Redox state of near infrared spectroscopy-measured cytochrome aa(3) correlates with delayed cerebral energy failure following perinatal hypoxia-ischaemia in the newborn pig.
Topics: Allopurinol; Animals; Animals, Newborn; Biotin; Brain; Cell Survival; Deferoxamine; Disease Models, Animal; Disease Progression; Electron Transport Complex IV; Energy Metabolism; Free Radical Scavengers; Hypoxia-Ischemia, Brain; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Neurons; Neuroprotective Agents; Oxidation-Reduction; Phosphates; Phosphocreatine; Predictive Value of Tests; Spectroscopy, Near-Infrared; Swine | 2004 |
Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Apoptosis; Biotin; Blotting, Western; Carcinoma; Carrier Proteins; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Male; Middle Aged; Polyps; Proteins; Two-Hybrid System Techniques | 2004 |
Clinicopathological study of the expression of syndecan-1 in invasive breast carcinomas. correlation with extracellular matrix components.
Topics: Avidin; Basement Membrane; Biotin; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cohort Studies; Collagen Type IV; Disease Progression; Disease-Free Survival; Extracellular Matrix; Fibroblast Growth Factor 2; Humans; Immunohistochemistry; Lymphatic Metastasis; Membrane Glycoproteins; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Proteoglycans; Receptors, Progesterone; Streptavidin; Syndecan-1; Syndecans; Tenascin; Time Factors; Tumor Suppressor Protein p53 | 2004 |
Correlation between serological immune response analyzed by a new ELISA for HPV-16/18 E7 oncoprotein and clinical characteristics of cervical cancer patients.
Topics: Antibodies, Viral; Antibody Specificity; Biomarkers; Biotin; Cancer Vaccines; Carcinoma; Disease Progression; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Vaccines; Precancerous Conditions; Recombinant Proteins; Sensitivity and Specificity; Streptavidin; Uterine Cervical Neoplasms; Vaccination | 2006 |
Subacute presentation of propionic acidemia.
Topics: Acidosis; Amino Acids; Biotin; Brain; Carnitine; Diagnosis, Differential; Diet, Protein-Restricted; Disease Progression; Electrophoresis, Capillary; Gastroenteritis; Growth Disorders; Humans; Infant; Magnetic Resonance Imaging; Male; Metabolism, Inborn Errors; Propionates; Propionic Acidemia; Treatment Outcome; Vomiting | 2007 |
CD30+ lymphocytes in chronic gingivitis from HIV-positive patients: a pilot study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Biotin; Case-Control Studies; CD30 Ligand; Chronic Disease; Disease Progression; Disease Susceptibility; Female; Gingivitis; HIV Seronegativity; HIV Seropositivity; Humans; Indicators and Reagents; Interleukin-4; Ki-1 Antigen; Ligands; Lymphocyte Count; Membrane Glycoproteins; Middle Aged; Pilot Projects; Receptors, Antigen, T-Cell; Streptavidin; T-Lymphocytes; Th1 Cells | 1997 |
Complete biotinidase deficiency presenting as reversible progressive ataxia and sensorineural deafness.
Topics: Amidohydrolases; Biotin; Biotinidase; Brain; Deafness; Disease Progression; Female; Follow-Up Studies; Genetic Carrier Screening; Humans; Infant; Neurologic Examination; Spinocerebellar Degenerations; Tomography, X-Ray Computed | 2002 |