Page last updated: 2024-09-05

biotin and Chronic Progressive Multiple Sclerosis

biotin has been researched along with Chronic Progressive Multiple Sclerosis in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (60.00)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Buonvicino, D; Chiarugi, A; Guasti, D; Pratesi, S; Ranieri, G1
Barbin, L; Couloume, L; Edan, G; Kerbrat, A; Laplaud, DA; Le Page, E; Le Port, D; Leray, E; Michel, L; Ory, S; Wiertlewski, S1
Assouad, R; Branger, P; Defer, G; Derache, N; Kassis, N; Maillart, E; Parienti, JJ1
Cohen, JA; Goldschmidt, CH1
Berger, E; Bourre, B; Camdessanche, JP; Castelnovo, G; Ciron, J; Clavelou, P; De Seze, J; Defer, G; Dulau, C; Edan, G; Gout, O; Guennoc, AM; Heinzlef, O; Labauge, P; Laplaud, D; Lebrun-Frenay, C; Magy, L; Maillart, E; Mathais, S; Mathey, G; Moisset, X; Moreau, T; Pelletier, J; Pereira, B; Taithe, F; Vermersch, P; Vukusic, S1
Arnold, D; Block, V; Comi, G; Cree, BAC; Cutter, G; Freedman, MS; Giovannoni, G; Hartung, HP; Kuhle, J; Lublin, FD; Munschauer, FE; Sedel, F; Wolinsky, JS1
De Roeck, Y; Philipse, E; Twickler, TB; Van Gaal, L1
Birnbaum, G; Stulc, J1
Dubois, C; Louapre, C; Lubetzki, C; Maillart, E; Pallier, C; Papeix, C; Pourcher, V; Todesco, E1
Acquaviva, C; Maillart, E; Maisonobe, T; Mochel, F; Stankoff, B1
Agius, P; Guillevin, C; Guillevin, R; Herpe, G; Maubeuge, N; Naudin, M; Philippe Neau, J; Ragot, S1
Bellanger, A; Galanaud, D; Gout, O; Lebrun-Frenay, C; Lyon-Caen, O; Papeix, C; Sedel, F; Touitou, V; Tourbah, A1
Brochet, B; Clanet, M; Clavelou, P; De Sèze, J; Debouverie, M; Defer, G; Edan, G; Gout, O; Labauge, P; Laplaud, DA; Lebrun-Frenay, C; Moreau, T; Papeix, C; Pelletier, J; Sedel, F; Tourbah, A; Vukusic, S1
Chataway, J1
Emerson, MR; Heidker, RM; LeVine, SM1

Reviews

1 review(s) available for biotin and Chronic Progressive Multiple Sclerosis

ArticleYear
Intersections of pathways involving biotin and iron relative to therapeutic mechanisms for progressive multiple sclerosis.
    Discovery medicine, 2016, Volume: 22, Issue:123

    Topics: Biotin; Cholesterol; Food; Heme; Humans; Iron; Lipid Metabolism; Mitochondria; Multiple Sclerosis, Chronic Progressive; Neurons; Nutritional Requirements; Oligodendroglia; Signal Transduction; Vitamin B Complex

2016

Trials

3 trial(s) available for biotin and Chronic Progressive Multiple Sclerosis

ArticleYear
Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial.
    The Lancet. Neurology, 2020, Volume: 19, Issue:12

    Topics: Adolescent; Adult; Aged; Biotin; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Outcome Assessment, Health Care; Severity of Illness Index; Vitamin B Complex; Walking Speed; Young Adult

2020
High doses of biotin in chronic progressive multiple sclerosis: a pilot study.
    Multiple sclerosis and related disorders, 2015, Volume: 4, Issue:2

    Topics: Adult; Aged; Biotin; Drug Administration Schedule; Evoked Potentials, Visual; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis, Chronic Progressive; Optic Nerve Diseases; Pilot Projects; Treatment Outcome; Visual Acuity; Vitamin B Complex

2015
MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:13

    Topics: Adult; Biotin; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Outcome Assessment, Health Care; Vitamin B Complex

2016

Other Studies

11 other study(ies) available for biotin and Chronic Progressive Multiple Sclerosis

ArticleYear
Neuroimmunological characterization of a mouse model of primary progressive experimental autoimmune encephalomyelitis and effects of immunosuppressive or neuroprotective strategies on disease evolution.
    Experimental neurology, 2019, Volume: 322

    Topics: Animals; Bezafibrate; Biotin; Dexamethasone; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Mice; Mice, Inbred NOD; Mitochondria; Multiple Sclerosis, Chronic Progressive; Neuroprotective Agents; Spinal Cord

2019
High-dose biotin in progressive multiple sclerosis: A prospective study of 178 patients in routine clinical practice.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2020, Volume: 26, Issue:14

    Topics: Adult; Biotin; Disability Evaluation; Disease Progression; Humans; Magnetic Resonance Imaging; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies

2020
Relapses During High-Dose Biotin Treatment in Progressive Multiple Sclerosis: a Case-Crossover and Propensity Score-Adjusted Prospective Cohort.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Aged; Biotin; Cohort Studies; Cross-Over Studies; Female; Follow-Up Studies; France; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Propensity Score; Vitamin B Complex

2020
The Rise and Fall of High-Dose Biotin to Treat Progressive Multiple Sclerosis.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Biotin; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Propensity Score; Prospective Studies; Recurrence

2020
Relapses in Patients Treated with High-Dose Biotin for Progressive Multiple Sclerosis.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:1

    Topics: Adult; Biotin; Case-Control Studies; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Recurrence; Retrospective Studies

2021
Misdiagnosis of Graves' hyperthyroidism due to therapeutic biotin intervention.
    Acta clinica Belgica, 2018, Volume: 73, Issue:5

    Topics: Biotin; Diagnostic Errors; Female; Graves Disease; Humans; Immunoassay; Middle Aged; Multiple Sclerosis, Chronic Progressive; Thyroid Function Tests

2018
High dose biotin as treatment for progressive multiple sclerosis.
    Multiple sclerosis and related disorders, 2017, Volume: 18

    Topics: Biotin; Brain; Disability Evaluation; Facial Pain; Female; Humans; Immunologic Factors; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Treatment Failure; Vitamin B Complex

2017
False hepatitis B and C viral serologies in patients with multiple sclerosis receiving high-dose biotin.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2020, Volume: 26, Issue:2

    Topics: Antibodies, Viral; Artifacts; Bacterial Proteins; Biotin; False Negative Reactions; False Positive Reactions; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Immunoassay; Multiple Sclerosis, Chronic Progressive

2020
Severe transient myopathy in a patient with progressive multiple sclerosis and high-dose biotin.
    Neurology, 2019, 05-28, Volume: 92, Issue:22

    Topics: Biotin; Female; Humans; Middle Aged; Multiple Sclerosis, Chronic Progressive; Muscle, Skeletal; Muscular Diseases; Vitamin B Complex

2019
    Annals of clinical and translational neurology, 2019, Volume: 6, Issue:7

    Topics: Biotin; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive

2019
Biotin in progressive multiple sclerosis: A new lead?
    Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:13

    Topics: Biotin; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive

2016