biotin has been researched along with Benign Neoplasms in 168 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (11.90) | 18.7374 |
| 1990's | 19 (11.31) | 18.2507 |
| 2000's | 37 (22.02) | 29.6817 |
| 2010's | 66 (39.29) | 24.3611 |
| 2020's | 26 (15.48) | 2.80 |
| Authors | Studies |
|---|---|
| Jakubowski, HV; McIntee, EJ; Richards, KA; Seiler, CL | 1 |
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| Jin, Y; Li, Y; Liu, W; Ma, X; Song, Y; Tang, Y; Wang, S; Zhang, J | 1 |
| Aki, S; Ishii, M; Ishikawa, S; Kanai, M; Kaneko, Y; Katoh, H; Kawamura, T; Kodama, T; Miura, M; Ohkubo, K; Osawa, T; Sugiyama, A; Takahashi, K; Tatsumi, T; Yamashita, T; Yamatsugu, K | 1 |
| He, X; Huang, Y; Wang, Z; Yu, J; Zhang, Q; Zhou, D | 1 |
| Jiang, WL; Li, CY; Li, Y; Mao, GJ; Tan, M; Wang, WX; Wang, ZQ | 1 |
| Dirksmeyer, T; Giese, M; Hirschhäuser, C; Knauer, S; Schmuck, C; Stahl, P; Vallet, C | 1 |
| Chang, X; Huang, S; Li, X; Liang, Y; Liu, W; Liu, Y; Lu, Y; Wang, S; Xu, Z; Yang, Z | 1 |
| Cui, L; Cui, X; Guo, X; Li, X; Li, Y; Liu, Z; Shi, Y; Yang, S; Yue, X; Zhang, Y | 1 |
| Hu, J; Li, DL; Qiu, JG; Wang, ZY; Yuan, H; Zhang, CY | 1 |
| Cao, H; Chen, D; Fang, Z; Lu, X; Shao, T; Tian, X; Tian, Y; Zhao, H | 1 |
| Miao, L; Pan, D; Wang, G; Wang, L; Wang, X; Wang, Y; Xu, N; Xu, Y; Yan, J; Yang, M; Yu, L | 1 |
| Jung, WH; Mok, H; You, G | 1 |
| Cai, X; Dong, Y; Hao, T; Yang, X; Yi, L; Zhang, Z | 1 |
| Li, H; Li, W; Shen, Y; Yin, S; Yuan, L; Zhang, XB | 1 |
| Ghadi, FE; Naeimi, A; Parizi, ZP; Rezakhani, MS | 1 |
| Chen, C; Li, H; Sun, R; Zeng, Z; Zhang, D; Zhang, X; Zhou, R; Zhou, X; Zhu, Q | 1 |
| Doehlemann, G; Misas Villamil, JC; Nakagami, H; Saur, IML; Shi, W; Stolze, SC | 1 |
| Carlton Ranjith, WA; Kundu, BK; Mukhopadhyay, S; Sarkar, S; Singh, S; Sonawane, A | 1 |
| Iloki-Assanga, S; Lujany, LML; McCarty, MF | 1 |
| Fu, T; Guo, Q; Hu, X; Huang, N; Huang, Q; Peng, M; Peng, W; Peng, Y; Tan, W; Wu, Z; Zhao, Z | 1 |
| Doi, H; Doi, T; Fujitani, H; Inoue, T; Kanai, M; Kawamura, T; Kawato, T; Kodama, T; Mizohata, E; Shimizu, Y; Shinoda, K; Sugiyama, A; Takahashi, K; Tanaka, T; Tatsumi, T; Yamashita, T; Yamatsugu, K | 1 |
| Chu, X; Jin, Y; Liu, J; Wu, C; Wu, Z; Zhang, W; Zi, Y | 1 |
| Chaudhuri, A; Jana, A; Mengji, R; Pradeep Singh, ND; Venkatesh, Y | 1 |
| Su, Q; Wang, X; Yang, J; Zhang, M; Zhang, Y; Zhang, Z | 1 |
| Geng, Z; Guo, T; Li, Z; Lu, J; Wang, Z; Yang, Z; Zhang, M | 1 |
| Hussain, MS; Ilyas, M; Ilyas, S; Iqbal, M; Mathur, S; Schlößer, HA; Ullah, NK; Wennhold, K | 1 |
| Kong, X; Li, M; Lin, W; Yin, Y; Zhang, Y | 1 |
| Kusamori, K | 1 |
| Balan, V; Dodi, G; Mihai, CT; Serban, AM; Ursachi, VC | 1 |
| Dong, D; Kong, F; Ren, M; Wang, S; Xu, Q; Yin, J | 1 |
| Lai, SK; Lin, Y; Park, SI; Parker, CL; Press, OW; Yang, Q | 1 |
| Fang, L; Gou, S; Hu, W; Hua, W | 1 |
| Gou, S; Hua, W; Xu, G; Zhao, J | 1 |
| Honda, T; Ojima, I; Vineberg, JG; Wang, T | 1 |
| Maiti, S; Paira, P | 1 |
| Li, K; Li, X; Lin, J; Liu, Q; Lv, G; Peng, Y; Qiu, L; Wang, S; Zhao, X | 1 |
| Dai, X; Han, H; Han, K; Ma, Z; Zhang, J | 1 |
| Dong, W; Li, K; Lin, J; Liu, Q; Lv, G; Qiu, L; Sun, X; Xie, M | 1 |
| An, J; Cheng, K; Li, C; Liu, B; Song, YY; Xuan, Y; Yang, XQ; Zhang, MZ; Zhang, XS; Zhao, YD | 1 |
| Bhatt, H; Biswas, S; Ghosh, B; Kumari, P; Rompicharla, SVK | 1 |
| Bolze, F; Heitz, V; Jenni, S; Sour, A; Ventura, B | 1 |
| Asghar, S; Dai, S; Feng, S; Jin, L; Shao, F; Wang, Y; Xiao, Y; Xu, M | 1 |
| Abou-Elkacem, L; Natarajan, A | 1 |
| Bhuniya, S; Han, JH; Jeon, HM; Kang, C; Kim, JS; Lee, JH; Maiti, S; Park, N | 1 |
| Chen, LJ; Jiang, X; Jin, RR; Li, X; Lin, GY; Lin, M; Lu, CT; Lv, HF; Shen, XT; Su, ZX; Zhang, M; Zhao, YZ | 1 |
| Barth, H; Fahrer, J; Fiedler, K; Gierschik, P; Langer, T; Schweitzer, B | 1 |
| Chen, L; Deng, X; Hao, S; Ma, L; Wei, W; Yao, Y | 1 |
| García-Celma, MJ; Melgar-Lesmes, P; Morral-Ruíz, G; Solans, C | 1 |
| Fan, R; Kim, DJ; Kim, GS; Kwak, M; Lee, G; Lee, SK | 1 |
| Cho, S; Choy, HE; Hong, Y; Kim, DM; Ko, SY; Lee, Y; Min, JJ; Park, JO; Park, S; Park, SH; Park, SJ | 1 |
| Jung, D; Kim, JS; Lee, JH; Maiti, S | 1 |
| Cho, Y; Jeon, S; Kim, YH; Lee, ES; Moon, JM | 1 |
| Camara, DT; Cordonier, EL; Liu, D; Zempleni, J | 1 |
| Chiang, YT; Lo, CL | 1 |
| Chatrou, M; Kusters, D; Reutelingsperger, CP; Schurgers, L; Ungethüm, L | 1 |
| Agostiano, A; Corricelli, M; Curri, ML; Denora, N; Depalo, N; Di Carlo, E; Fanizza, E; Laquintana, V; Striccoli, M | 1 |
| Li, Q; Marek, P; Yi, L | 1 |
| Bovin, N; Chinarev, A; Fedier, A; Heinzelmann-Schwarz, V; Jacob, F; Pochechueva, T | 1 |
| Cho, Y; Hong, WY; Jeon, SH; Lee, ES | 1 |
| Ojima, I; Vineberg, JG; Wang, T; Zuniga, ES | 1 |
| Chen, S; Cheng, SX; Feng, J; Jia, HZ; Peng, MY; Qin, SY; Rong, L; Zhang, XZ | 1 |
| Bag, N; Mathur, R; Mishra, AK; Shukla, G; Singh, B; Singh, S; Tiwari, AK; Varshney, R | 1 |
| Dickinson, NJ; Dzubak, P; Gurska, S; Hajduch, M; Hodon, J; Sarek, J; Sidova, V; Soural, M; Urban, M | 1 |
| Chen, X; Fan, X; Li, H | 1 |
| Amini, M; Darvishi, MH; Dinarvand, R; Hashemzadeh, H; Nomani, A; Shokrgozar, MA | 1 |
| Ansari, A; Imoukhuede, PI; Naumovski, V; Patel, R; Schultheis, K | 1 |
| Kim, JS; Lee, YH; Lin, W; Tang, Y; Verwilst, P | 1 |
| Fong, WP; Lo, PC; Ng, DK; Shi, WJ; Wang, Q; Wong, RC; Zhao, S | 1 |
| Branca, C; Di Pietro, A; Galvagno, S; Giofré, SV; Iannazzo, D; Pistone, A; Romeo, R; Salamò, M; Visalli, G | 1 |
| Cho, SH; James, TD; Jang, JH; Kang, C; Kim, JS; Kim, WR; Sharma, A | 1 |
| Appold, L; Dasgupta, A; Fokong, S; Iranzo, O; Kiessling, F; Koczera, P; Kuehne, AJC; Lammers, T; Liu, M; Ojha, T; Pathak, V; Pich, A; Shi, Y; van Zandvoort, M; Wu, Z | 1 |
| Cheng, Y; Wang, X; Wen, LP; Xu, T; Yang, W | 1 |
| Choyke, PL; Kobayashi, H; Kosaka, N; Ogawa, M | 1 |
| Hiraoka, M; Kiyono, Y; Kizaka-Kondoh, S; Kudo, T; Kuge, Y; Masutani, M; Mukai, T; Saji, H; Tanaka, S; Ueda, M | 1 |
| Tian, L; Wei, W; Xue, JL | 1 |
| Chen, J; Chen, S; Kuznetsova, LV; Ojima, I; Wong, SS; Zhao, X | 1 |
| Ha, KS; Jung, SH; Kim, YM; Park, JY; Shin, I; Yoo, JO | 1 |
| Pang, QX; Qu, Y; Wei, DP; Zhao, FY | 1 |
| Baio, G; de Totero, D; Fabbi, M; Ferrini, S; Neumaier, CE; Salvi, S; Truini, M | 1 |
| Chu, CY; Kuo, CC; Lin, JJ; Lo, LC | 1 |
| Pèlegrin, A; Robert, B | 1 |
| Santra, S | 1 |
| CLOWES, GH; HARRIS, PN; KRAHL, ME | 1 |
| Chen, J; Chen, S; Kuznetsova, L; Ojima, I; Wong, SS; Zhao, X | 1 |
| Weitz, JI | 1 |
| McEwan, J; McTavish, K; Russell-Jones, G | 1 |
| Albertoni, C; Anastasi, AM; D'Alessio, V; De Santis, R; Deiana, K; Ferrari, LE; Leoni, B; Lindstedt, R; Manganello, S; Paganelli, G; Pelliccia, A; Petronzelli, F; Rosi, A | 1 |
| RITCHEY, MG; TATUM, EL | 1 |
| Chen, L; Chen, X; Dou, S; Hnatowich, DJ; Liu, G; Liu, X; Rusckowski, M | 1 |
| Breyer, S; Diestel, R; Effenberger-Neidnicht, K; Mahal, K; Sasse, F; Schobert, R | 1 |
| Chen, H; Liu, Z; Wang, S; Yuan, B; Zheng, Z | 1 |
| Ding, RM; He, H; Li, J | 1 |
| Bakhtiar, R; Chen, D; Verch, T; Yin, KC | 1 |
| Qu, W; Sun, YX; Zeng, X; Zhang, XZ; Zhuo, RX | 1 |
| Chen, L; Cheng, D; Dou, S; Hnatowich, DJ; Liu, G; Liu, X; Liu, Y; Rusckowski, M; Xiao, N | 1 |
| Chen, LD; Huang, GL; Liu, GJ; Lu, MD; Wang, W; Xie, XY; Xu, ZF; Zhou, LY | 1 |
| Bauwens, M; Bormans, G; de Witte, P; Marysael, T; Ni, Y; Rozenski, J | 1 |
| Chung, DS; Piao, JY | 1 |
| Kearney, L; Shipley, J | 1 |
| Amadei, GA; Breadner, D; Cho, CF; Lewis, JD; Luyt, LG | 1 |
| Chen, WH; Cheng, SX; Kuang, Y; Qu, W; Zeng, X; Zhang, XZ; Zhou, X; Zhuo, RX | 1 |
| Hughey, BJ; Klinkowstein, RE; Laforest, R; Lewis, MR; Margenau, WH; Reichert, DE; Shefer, RE; Welch, MJ | 1 |
| Chinol, M; Paganelli, G | 1 |
| Grapputo, A; Hytönen, VP; Kalkkinen, N; Kettunen, A; Kulomaa, MS; Laitinen, OH; Marttila, AT; Nordlund, HR; Nyholm, TK; Paganelli, G; Savolainen, J | 1 |
| Barbet, J; Chang, CH; Chatal, JF; Goldenberg, DM; Hansen, HJ; Karacay, H; McBride, W; Rossi, EA; Sharkey, RM | 1 |
| Boerman, OC; Corstens, FH; Oyen, WJ; van Schaijk, FG | 1 |
| Chen, G; Huang, S; Liu, L; Lu, M; Wang, P; Zhang, C; Zhang, S; Zhang, Y; Zhou, X | 1 |
| Baranowska-Kortylewicz, J; Batra, SK; Booth, BJ; Colcher, D; Pavlinkova, G | 1 |
| Chelli, M; Chinol, M; De Luca, A; Ginanneschi, M; Leone, G; Paganelli, G; Papi, S; Papini, AM; Sabatino, G | 1 |
| AXELROD, AE; HOFMANN, K | 1 |
| Brooks, SA; Wilkinson, D | 1 |
| Daa, T; Gamachi, A; Kashima, K; Nakatani, Y; Tsujimoto, M; Yokoyama, S | 1 |
| Flowers, L; Horowitz, IR; Huang, R; Huang, RP; Lin, Y; Parthasarathy, S; Ramachandran, S; Shi, Q | 1 |
| BURGEL, E | 1 |
| Corti, A | 1 |
| Szekeres, G | 1 |
| Abe, Y; Inayama, Y; Ito, T; Kashima, K; Kitamura, H; Mark, EJ; Masudo, K; Nakatani, Y; Notohara, K; Nozawa, A; Resl, M; Tamai, S; Tsujimoto, M; Yamanaka, S; Yokoyama, S | 1 |
| BALLANTYNE, RM; McHENRY, EW | 1 |
| Balthasar, S; Kreuter, J; Langer, K; Michaelis, K; Strebhardt, K; Wartlick, H | 1 |
| Bockmühl, U; Donhuijsen, K; Korinth, D; Petersen, I | 1 |
| Barbet, J; Gruaz-Guyon, A; Raguin, O | 1 |
| Agnantis, NJ; Briasoulis, E; Charchanti, A; Damala, K; Ioachim, E; Karavasilis, V; Pavlidis, N; Tsanou, E | 1 |
| Cardillo, TM; Chang, CH; Goldenberg, DM; Horak, ID; Karacay, H; McBride, WJ; Rossi, EA; Sharkey, RM | 1 |
| Shimkets, RA | 1 |
| Lam, KS; Liu, R; Marik, J; Peng, L; Takada, Y; Wang, X | 1 |
| Mayer, A; Wilkins, DK | 1 |
| Tharapel, AT; Wachtel, SS | 1 |
| Buchsbaum, DJ; Meredith, RF | 1 |
| Ojima, I | 1 |
| Cheng, C; Cheng, H; Cheng, SX; Gu, ZW; Li, C; Shi, BX; Wei, H; Zhang, XZ; Zhuo, RX | 1 |
| Alberte-Lista, L; Buriticá, C; Cameselle-Teijeiro, J; Chiarelli, S; Gonçalves, L; González-Cámpora, R; Nogales, FF | 1 |
| Hashizume, K; Hatanaka, Y; Ichimura, K; Imaoka, Y; Kamihara, Y; Tani, Y; Torisu, K; Yoshino, T | 1 |
| THOMPSON, JW; VOEGTLIN, C | 1 |
| Blanco Quirós, A | 1 |
| Denk, H; Klein, PJ; Otto, HF; Seifert, G; Stein, H | 1 |
| Berenson, R; Colter, M; Corpuz, S; Heimfeld, S; Kalamasz, D; Stray, KM | 1 |
| Hnatowich, DJ | 1 |
| Darzynkiewicz, Z; Gorczyca, W; Kram, A; Melamed, MR; Tuziak, T | 1 |
| Cohen-Haguenauer, O; Healy, JC; Jouve, C; Rhoer-Moja, S; Vindimian, M | 1 |
| Nishigori, H; Oda, K; Ogihara-Umeda, I; Sasaki, T; Senda, M; Toyama, H | 1 |
| Cooke, TG; Fenton-Lee, D; McNicol, AM; Ozanne, BW; Reeves, JR; Richards, RC; Walsh, A | 1 |
| Dedrick, RL; Sung, C; van Osdol, WW; Weinstein, JN | 1 |
| Espinosa, R; Le Beau, MM | 1 |
| Niitsu, Y; Sato, Y; Watanabe, N; Yamauchi, N | 1 |
| Colombo, B; Corti, A; Curnis, F; Gasparri, A; Magni, F; Sacchi, A; Sangregorio, R; Siccardi, AG | 1 |
| Holt, H; Parham, DM | 1 |
| Buhler, KR; Hamlin, DK; Klumb, LA; Pathare, PM; Stayton, PS; To, R; Vessella, RL; Wilbur, DS | 1 |
| Howard, M; Kaplan, D | 1 |
| Bensinger, WI; Berenson, RJ; Berninger, RW; Goffe, RA; Heimfeld, S; Kalamasz, DF; Peterson, DR; Strong, DM; Thompson, P | 1 |
| Clarke, NW; Griffin, MM; Maier, H; Steven, FS; Williams, LA | 1 |
| Kallio, P; Syrjänen, K; Syrjänen, S; Tervahauta, A | 1 |
| Gabius, HJ; Gabius, S; Kayser, K | 1 |
| Fazio, F; Malcovati, M; Paganelli, G | 1 |
| Bensinger, WI; Berenson, RJ | 1 |
| Fields, K; Jin, L; Lloyd, RV | 1 |
| Bittel, D; Dalquen, P; Gudat, F; Heitz, PU; von Overbeck, J | 1 |
| Hagen, KA; Swanson, PE; Wick, MR | 1 |
| Frizzera, G; Michels, S; Swanson, PE; Wick, MR | 1 |
| Shah, KD; Tabibzadeh, SS | 1 |
| Klibanov, AL; Mukhamedova, NM; Obukhov, SK; Slinkin, MA; Torchilin, VP | 1 |
| Avner, BP; Husseini, S; Kimbro, B; Liao, SK; Meranda, C; Oldham, RK; Romano, T | 1 |
| Chesa, PG; Melamed, MR; Old, LJ; Rettig, WJ; Thomson, TM | 1 |
| Biagini, G; D'Errico, A; Garbisa, S; Grigioni, WF; Mancini, AM; Milani, M; Rizzoli, R; Vasi, V; Villanacci, V | 1 |
| Fujita, S; Matsubara, F; Matsuda, T | 2 |
| Baldwin, RW; Fells, HF; Perkins, AC; Pimm, MV | 1 |
| Hennebert, PE | 1 |
22 review(s) available for biotin and Benign Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
Cupid and Psyche system for the diagnosis and treatment of advanced cancer.
Topics: Animals; Antineoplastic Agents; Biotin; Cell Line, Tumor; Drug Delivery Systems; Humans; Immunotherapy; Neoplasms; Precision Medicine; Single-Chain Antibodies; Streptavidin | 2019 |
Development of Advanced Cell-Based Therapy by Regulating Cell-Cell Interactions.
Topics: Animals; Avidin; Biotin; Bone Marrow Cells; Cell Communication; Cell Survival; Cell Transplantation; Cell- and Tissue-Based Therapy; Diabetes Mellitus; Endothelial Cells; Fibroblasts; Humans; Insulin-Secreting Cells; Mesenchymal Stem Cells; Neoplasms; Piperazines; Spheroids, Cellular; Wound Healing | 2021 |
Biotinylated chitosan macromolecule based nanosystems: A review from chemical design to biological targets.
Topics: Biotin; Biotinylation; Chitosan; Drug Delivery Systems; Humans; Macromolecular Substances; Molecular Imaging; Nanostructures; Nanotechnology; Neoplasms | 2021 |
Biotin conjugated organic molecules and proteins for cancer therapy: A review.
Topics: Antineoplastic Agents; Biotin; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neoplasms; Organic Chemicals; Proteins; Structure-Activity Relationship | 2018 |
Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolism.
Topics: Biomarkers, Tumor; Biotin; Biotinylation; Carbon-Nitrogen Ligases; DNA-Binding Proteins; Gene Expression; Gene Expression Regulation; Glycolysis; Heat-Shock Proteins; Humans; Myelin Basic Protein; Neoplasms; Phosphopyruvate Hydratase; Tumor Suppressor Proteins | 2014 |
Antibodies and their multivalent constructs for cancer therapy.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Bacterial Proteins; Biotin; Humans; Immunoconjugates; Immunoglobulin Fragments; Leucine Zippers; Nanoparticles; Neoplasms; Protein Engineering; Protein Structure, Tertiary; Recombinant Fusion Proteins | 2014 |
Vector retargeting for cancer gene therapy.
Topics: Avidin; Biotin; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Genome, Viral; Humans; Ligands; Neoplasms; Recombinant Fusion Proteins; Tropism | 2009 |
[Bispecific antibodies: what future?].
Topics: Antibodies, Bispecific; Antibody Specificity; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Avidin; Biotin; Drug Delivery Systems; Drug Design; Epitopes; Forecasting; Haptens; Humans; Immunoglobulin Fragments; Neoplasm Proteins; Neoplasms; Protein Engineering; Structure-Activity Relationship | 2009 |
Potential of new anticoagulants in patients with cancer.
Topics: Anticoagulants; Benzimidazoles; Biotin; Clinical Trials as Topic; Dabigatran; Humans; Morpholines; Neoplasms; Oligosaccharides; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiophenes; Thrombosis | 2010 |
[Research progress of polyamidoamine dendrimer in targeting drug delivery system].
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Biotin; Dendrimers; Drug Carriers; Drug Delivery Systems; Folic Acid; Gene Transfer Techniques; Humans; Ligands; Neoplasms; Polyamines; Polyethylene Glycols; Transferrin | 2011 |
Pretargeted radioimmunotherapy of cancer: progress step by step.
Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Avidin; Biotin; Humans; Neoplasms; Radioimmunotherapy; Streptavidin | 2003 |
[Are there new possibilities in immunomorphology?].
Topics: Animals; Avidin; Biomarkers, Tumor; Biotin; Fluorescent Antibody Technique, Direct; Fluorescent Antibody Technique, Indirect; History, 20th Century; Humans; Immunoenzyme Techniques; Immunohistochemistry; Neoplasms; Polymers | 2004 |
Recent advances in pretargeted radioimmunotherapy.
Topics: Animals; Antibodies, Bispecific; Avidin; Biotin; Epitopes; Haptens; Humans; Neoplasms; Peptides; Radioimmunotherapy; Radioisotopes; Streptavidin | 2005 |
Development of antibodies for cancer therapy.
Topics: Animals; Antibodies; Biotin; Cancer Vaccines; Chemistry, Pharmaceutical; Colorectal Neoplasms; Humans; Immunoglobulin Fragments; Immunoglobulin G; Immunotoxins; Mice; Neoplasm Transplantation; Neoplasms; Radioimmunotherapy; Streptavidin | 2006 |
Pretargeted radioimmunotherapy.
Topics: Animals; Antibodies, Bispecific; Antibody Specificity; Biotin; Clinical Trials, Phase I as Topic; Humans; Mice; Mice, Nude; Models, Animal; Neoplasms; Radioimmunotherapy; Streptavidin; Transplantation, Heterologous; Yttrium Radioisotopes | 2006 |
Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads.
Topics: Animals; Antibodies, Monoclonal; Biotin; Drug Carriers; Drug Design; Fluorescent Dyes; Humans; Immunotoxins; Nanotubes, Carbon; Neoplasms; Taxoids | 2008 |
Development of new biotin/streptavidin reagents for pretargeting.
Topics: Affinity Labels; Antibodies, Monoclonal; Biotin; Cross-Linking Reagents; Humans; Indicators and Reagents; Iodine Radioisotopes; Mutagenesis, Site-Directed; Neoplasms; Protein Engineering; Protein Structure, Quaternary; Radioimmunotherapy; Streptavidin | 1999 |
Applications of enzymatic amplification staining in immunophenotyping hematopoietic cells.
Topics: Biotin; Flow Cytometry; Fluorescent Antibody Technique; Hematopoietic Stem Cells; Horseradish Peroxidase; Humans; Immunophenotyping; Lymphocyte Subsets; Neoplasms; Sensitivity and Specificity; Staining and Labeling; Tyramine | 2002 |
[Biotinylated ligands for receptor localization. An alternative for immunohistochemistry].
Topics: Animals; Binding Sites; Biomarkers, Tumor; Biotin; Cytokines; Epidermal Growth Factor; Gangliosides; Glycoproteins; Histocytochemistry; Hormones; Humans; Ligands; Neoplasms | 1991 |
Monoclonal antibody pretargetting techniques for tumour localization: the avidin-biotin system. International Workshop on Techniques for Amplification of Tumour Targetting.
Topics: Animals; Antibodies, Monoclonal; Avidin; Bacterial Proteins; Biotin; Humans; Neoplasms; Radionuclide Imaging; Streptavidin | 1991 |
Peripheral blood and positive selection of marrow as a source of stem cells for transplantation.
Topics: Avidin; Biotin; Blood Cell Count; Blood Component Removal; Blood Transfusion, Autologous; Bone Marrow Transplantation; Hematopoietic Stem Cell Transplantation; Humans; Immunosorbent Techniques; Neoplasms | 1990 |
146 other study(ies) available for biotin and Benign Neoplasms
| Article | Year |
|---|---|
Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B.
Topics: Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Protein Conformation; Protein Isoforms; Protein Tyrosine Phosphatase, Non-Receptor Type 1 | 2013 |
Chlorin e6-Biotin Conjugates for Tumor-Targeting Photodynamic Therapy.
Topics: Antineoplastic Agents; Biotin; Cell Survival; Chlorophyllides; HeLa Cells; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents | 2021 |
Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system.
Topics: Animals; Biotin; Cell Line, Tumor; Cloning, Molecular; Escherichia coli; Gene Expression; Humans; Immunoconjugates; Mice; Mice, Inbred BALB C; Neoplasms; Protein Folding; Receptor, ErbB-2; Streptavidin | 2022 |
Iodine Conjugated Pt(IV) Nanoparticles for Precise Chemotherapy with Iodine-Pt Guided Computed Tomography Imaging and Biotin-Mediated Tumor-Targeting.
Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cisplatin; Humans; Iodine; Nanoparticles; Neoplasms; Platinum; Theranostic Nanomedicine; Tissue Distribution; Tomography, X-Ray Computed | 2022 |
A tumor-targeting near-infrared fluorescent probe for real-time imaging ATP in cancer cells and mice.
Topics: Adenosine Triphosphate; Animals; Biotin; Fluorescent Dyes; Mice; Neoplasms; Rhodamines | 2022 |
Advances towards Cell-Specific Gene Transfection: A Small-Molecule Approach Allows Order-of-Magnitude Selectivity.
Topics: Biotin; Cell Line; Genetic Vectors; Humans; Neoplasms; Transfection | 2022 |
Biotin-Targeted Au(I) Radiosensitizer for Cancer Synergistic Therapy by Intervening with Redox Homeostasis and Inducing Ferroptosis.
Topics: Antineoplastic Agents; Auranofin; Biotin; Cell Line, Tumor; Ferroptosis; Homeostasis; Neoplasms; Oxidation-Reduction; Radiation-Sensitizing Agents; Thioredoxin-Disulfide Reductase | 2022 |
Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy.
Topics: Biomimetics; Biotin; Doxorubicin; Humans; Nanoparticles; Neoplasms; Phototherapy; Photothermal Therapy | 2022 |
Hydroxymethylation-Specific Ligation-Mediated Single Quantum Dot-Based Nanosensors for Sensitive Detection of 5-Hydroxymethylcytosine in Cancer Cells.
Topics: 5-Methylcytosine; Animals; Biotin; DNA; DNA Methylation; Mammals; Neoplasms; Quantum Dots | 2022 |
A cyclometallated iridium(III) complex with multi-photon absorption properties as an imaging-guided photosensitizer.
Topics: Biotin; Humans; Iridium; Neoplasms; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen | 2022 |
Feasibility of in vivo CAR T cells tracking using streptavidin-biotin-paired positron emission tomography.
Topics: Biotin; Cell Line, Tumor; Feasibility Studies; Gallium Radioisotopes; Humans; Neoplasms; Positron-Emission Tomography; Receptors, Chimeric Antigen; Streptavidin; T-Lymphocytes | 2022 |
Different Influences of Biotinylation and PEGylation on Cationic and Anionic Proteins for Spheroid Penetration and Intracellular Uptake to Cancer Cells.
Topics: Amines; Anions; Biotin; Biotinylation; Humans; Ligands; Muramidase; Neoplasms; Polyethylene Glycols; Serum Albumin, Bovine | 2022 |
A biotin-guided near-infrared fluorescent probe for imaging hydrogen sulfide and differentiating cancer cells.
Topics: Biotin; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Neoplasms; Optical Imaging | 2023 |
Molecular Engineering of pH-Responsive NIR Oxazine Assemblies for Evoking Tumor Ferroptosis via Triggering Lysosomal Dysfunction.
Topics: Biotin; Cell Line, Tumor; Doxorubicin; Ferroptosis; Humans; Hydrogen-Ion Concentration; Lysosomes; Nanoparticles; Neoplasms; Tumor Microenvironment | 2023 |
Topics: Biotin; Chitosan; Curcumin; Drug Carriers; Gallium Radioisotopes; Nanocomposites; Nanoparticles; Neoplasms; Spectroscopy, Fourier Transform Infrared | 2023 |
Rational design of nonlinear hybridization immunosensor chain reactions for simultaneous ultrasensitive detection of two tumor marker proteins.
Topics: alpha-Fetoproteins; Biomarkers, Tumor; Biosensing Techniques; Biotin; DNA; Humans; Immunoassay; Male; Neoplasm Proteins; Neoplasms; Streptavidin | 2023 |
Combination of in vivo proximity labeling and co-immunoprecipitation identifies the host target network of a tumor-inducing effector in the fungal maize pathogen Ustilago maydis.
Topics: Biotin; Fungal Proteins; Ligases; Neoplasms; Plant Diseases; Ustilago; Zea mays | 2023 |
Chitosan-Biotin-Conjugated pH-Responsive Ru(II) Glucose Nanogel: A Dual Pathway of Targeting Cancer Cells and Self-Drug Delivery.
Topics: Animals; Biotin; Chitosan; Glucose; Humans; Hydrogen-Ion Concentration; Nanogels; Neoplasms; Zebrafish | 2023 |
Nutraceutical targeting of TLR4 signaling has potential for prevention of cancer cachexia.
Topics: 3-Hydroxybutyric Acid; Adipocytes; Biotin; Cachexia; Carnitine; Catechin; Coumaric Acids; Dietary Supplements; Fatty Acids, Omega-3; Glycine; Humans; Macrophages; Muscle, Skeletal; Neoplasms; Phycobilins; Phycocyanin; Signal Transduction; Tea; Toll-Like Receptor 4 | 2019 |
Tumor Extracellular pH-Driven Cancer-Selective Artificial Receptor-Mediated Tumor-Targeted Fluorescence Imaging.
Topics: Amino Acid Motifs; Animals; Biotin; Carbocyanines; Cell Line, Tumor; Humans; Hydrogen-Ion Concentration; Mice; Neoplasms; Neoplasms, Experimental; Optical Imaging; Peptides; Receptors, Artificial; Streptavidin; Tumor Microenvironment | 2019 |
Size-adaptable and ligand (biotin)-sheddable nanocarriers equipped with avidin scavenging technology for deep tumor penetration and reduced toxicity.
Topics: Animals; Avidin; Biotin; Ligands; Liposomes; Mice; Neoplasms; Technology | 2020 |
An improved tumor-specific therapeutic strategy by the spatio-temporally controlled in situ formation of a Cu(ii) complex, leading to prompt cell apoptosis via photoactivation of a prodrug.
Topics: Antineoplastic Agents; Apoptosis; Biotin; Cell Line; Chelating Agents; Coordination Complexes; Copper; Humans; Ligands; Light; Neoplasms; Nitrobenzenes; Photolysis; Prodrugs; Pyridines; Thiones | 2020 |
Biotinylated platinum(ii) metallacage towards targeted cancer theranostics.
Topics: Biotin; Cell Line, Tumor; Cell Survival; Coordination Complexes; Fluorescent Dyes; Humans; Microscopy, Confocal; Neoplasms; Platinum; Theranostic Nanomedicine | 2020 |
Targeted copper supplementation oriented theranostic for fluorescence and
Topics: Animals; Antineoplastic Agents; Apoptosis; Biotin; Cell Line, Tumor; Coordination Complexes; Copper; Endoplasmic Reticulum; Fluorine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Mice; Neoplasms; Optical Imaging; Reactive Oxygen Species; Theranostic Nanomedicine; Transplantation, Heterologous | 2020 |
Mediating the Fate of Cancer Cell Uptake: Dual-Targeted Magnetic Nanovectors with Biotin and Folate Surface Ligands.
Topics: Biotin; Folic Acid; Humans; Ligands; Magnetic Phenomena; Magnetics; Neoplasms | 2020 |
The development of a biotin-guided and mitochondria-targeting fluorescent probe for detecting SO
Topics: Animals; Biotin; Fluorescent Dyes; HeLa Cells; Humans; Mitochondria; Neoplasms; Optical Imaging; Sulfur Dioxide; Zebrafish | 2021 |
A biotin-guided two-photon fluorescent probe for detection of hydrogen peroxide in cancer cells ferroptosis process.
Topics: Biotin; Ferroptosis; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Peroxide; Neoplasms | 2021 |
Pretargeting with bispecific fusion proteins facilitates delivery of nanoparticles to tumor cells with distinct surface antigens.
Topics: Animals; Antibodies, Bispecific; Antigens, CD20; Antigens, Neoplasm; Biotin; Cell Line, Tumor; Female; Glycoproteins; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Phagocytosis; Polyethylene Glycols; Polystyrenes; Recombinant Fusion Proteins; Tissue Distribution | 2017 |
Biotin-Pt (IV)-indomethacin hybrid: A targeting anticancer prodrug providing enhanced cancer cellular uptake and reversing cisplatin resistance.
Topics: A549 Cells; Biotin; Cisplatin; Drug Resistance, Neoplasm; Hep G2 Cells; Humans; Indomethacin; Neoplasms; Organoplatinum Compounds; Prodrugs | 2017 |
Biotinylated platinum(IV) complexes designed to target cancer cells.
Topics: Antineoplastic Agents; Biotin; Biotinylation; Coordination Complexes; Drug Delivery Systems; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Platinum | 2017 |
Design and synthesis of tumor-targeting theranostic drug conjugates for SPECT and PET imaging studies.
Topics: Animals; Biotin; Chelating Agents; Click Chemistry; Copper; Drug Design; Neoplasms; Positron-Emission Tomography; Rhenium; Taxoids; Theranostic Nanomedicine; Tomography, Emission-Computed, Single-Photon; Triazines | 2018 |
Enhanced Tumor Diagnostic and Therapeutic Effect of Mesoporous Silica Nanoparticle-Mediated Pre-targeted Strategy.
Topics: Aza Compounds; Biotin; Cell Survival; Cyclooctanes; Drug Carriers; Fluorescein-5-isothiocyanate; Fluorescent Dyes; HeLa Cells; Humans; Inhibitory Concentration 50; Intravital Microscopy; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Porosity; Ruthenium Compounds; Silicon Dioxide | 2018 |
Steric shielding protected and acidity-activated pop-up of ligand for tumor enhanced photodynamic therapy.
Topics: Animals; Biotin; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Ligands; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Peptides; Photochemotherapy; Static Electricity; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
A biotin receptor-targeted silicon(IV) phthalocyanine for in vivo tumor imaging and photodynamic therapy.
Topics: Animals; Biotin; Cross-Linking Reagents; HeLa Cells; Heterografts; Humans; Indoles; Isoindoles; Mice; Neoplasms; Organosilicon Compounds; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Receptors, Growth Factor; Solubility; Tissue Distribution | 2019 |
Topics: Animals; Antineoplastic Agents; Biotin; Combined Modality Therapy; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Therapy; Genetic Therapy; HeLa Cells; Humans; Hyperthermia, Induced; Mice, Nude; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Oligonucleotides, Antisense; Phototherapy; Radiotherapy, Image-Guided; Theranostic Nanomedicine; Treatment Outcome | 2018 |
Biotin functionalized PEGylated poly(amidoamine) dendrimer conjugate for active targeting of paclitaxel in cancer.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Biotin; Cell Survival; Dendrimers; Drug Carriers; Humans; Neoplasms; Paclitaxel; Polyethylene Glycols; Spheroids, Cellular; Tumor Cells, Cultured | 2019 |
Tumour-targeting photosensitisers for one- and two-photon activated photodynamic therapy.
Topics: Biotin; Cell Death; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Neoplasms; Photochemotherapy; Photons; Photosensitizing Agents; Porphyrins | 2019 |
Mesenchymal stem cells-curcumin loaded chitosan nanoparticles hybrid vectors for tumor-tropic therapy.
Topics: Animals; Biotin; Cell Movement; Cell Survival; Chitosan; Curcumin; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fluorescent Antibody Technique; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Nanoparticles; Neoplasms; Polymers; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
FN3 Protein Conjugates for Cancer Diagnosis and Imaging Studies.
Topics: Animals; Biotin; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Drug Carriers; Fibronectin Type III Domain; Humans; Ligands; Mice; Molecular Imaging; Neoplasms | 2019 |
Gemcitabine-coumarin-biotin conjugates: a target specific theranostic anticancer prodrug.
Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cell Survival; Coumarins; Deoxycytidine; Drug Delivery Systems; Fluorescent Dyes; Gemcitabine; Humans; Neoplasms; Prodrugs; Sulfhydryl Compounds | 2013 |
Construction and application of biotin-poloxamer conjugate micelles for chemotherapeutics.
Topics: Animals; Antibiotics, Antineoplastic; Biotin; Drug Carriers; Epirubicin; HL-60 Cells; Humans; Male; Mice; Mice, Nude; Micelles; Neoplasms; Poloxamer | 2013 |
C2-streptavidin mediates the delivery of biotin-conjugated tumor suppressor protein p53 into tumor cells.
Topics: Animals; Biotin; Chlorocebus aethiops; Drug Delivery Systems; HeLa Cells; Humans; Microscopy, Confocal; Neoplasms; Recombinant Proteins; Streptavidin; Surface Plasmon Resonance; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vero Cells | 2013 |
Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities.
Topics: Animals; Biotin; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Proliferation; Dendritic Cells; Exosomes; Female; Immunotherapy; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms; Phenotype; T-Lymphocytes, Cytotoxic | 2013 |
Multifunctional polyurethane-urea nanoparticles to target and arrest inflamed vascular environment: a potential tool for cancer therapy and diagnosis.
Topics: Angiogenesis Inhibitors; Animals; Antibodies; Biotin; Cell Proliferation; Drug Carriers; Endothelial Growth Factors; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Mice; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Peptides, Cyclic; Polyurethanes; Streptavidin; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Specific rare cell capture using micro-patterned silicon nanowire platform.
Topics: Biosensing Techniques; Biotin; Cell Line, Tumor; Cell Separation; Humans; Nanowires; Neoplasms; Protein Binding; Silicon; Streptavidin; Surface Properties; Tissue Array Analysis | 2014 |
New paradigm for tumor theranostic methodology using bacteria-based microrobot.
Topics: Animals; Bacteria; Biotin; Carbocyanines; Cell Line; Cell Line, Tumor; Mice; Microspheres; Neoplasms; NIH 3T3 Cells; Polystyrenes; Robotics; Streptavidin | 2013 |
Rational design of biotin-disulfide-coumarin conjugates: a cancer targeted thiol probe and bioimaging.
Topics: Biotin; Cell Line, Tumor; Coumarins; Disulfides; Endocytosis; Fluorescent Dyes; Humans; Molecular Probes; Neoplasms; Optical Imaging; Receptors, Growth Factor | 2014 |
An electroactive biotin-doped polypyrrole substrate that immobilizes and releases EpCAM-positive cancer cells.
Topics: Antigens, Neoplasm; Biotin; Cell Adhesion Molecules; Electric Conductivity; Epithelial Cell Adhesion Molecule; Humans; Neoplasms; Polymers; Pyrroles; Streptavidin; Surface Properties; Tumor Cells, Cultured | 2014 |
pH-responsive polymer-liposomes for intracellular drug delivery and tumor extracellular matrix switched-on targeted cancer therapy.
Topics: Acrylamides; Animals; Antineoplastic Agents; Biotin; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Extracellular Matrix; Female; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polyethylene Glycols; Polymers; Tissue Distribution | 2014 |
Molecular imaging of cell death in tumors. Increasing annexin A5 size reduces contribution of phosphatidylserine-targeting function to tumor uptake.
Topics: Animals; Annexin A5; Apoptosis; Biotin; Half-Life; HT29 Cells; Humans; Hydrazines; Magnetic Resonance Imaging; Mice; Mice, Nude; Microscopy, Confocal; Neoplasms; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Radiography; Recombinant Proteins; Streptavidin; Tissue Distribution; Transplantation, Heterologous | 2014 |
Biotin-decorated silica coated PbS nanocrystals emitting in the second biological near infrared window for bioimaging.
Topics: Amines; Biotin; Fluorescein-5-isothiocyanate; Humans; Lead; Nanoparticles; Neoplasms; Particle Size; Silicon Dioxide; Spectroscopy, Near-Infrared; Streptavidin; Sulfides | 2014 |
PEGylation of microbead surfaces reduces unspecific antibody binding in glycan-based suspension array.
Topics: Biotin; Female; Fluoroimmunoassay; High-Throughput Screening Assays; Humans; Immunoglobulin G; Immunoglobulin M; Microspheres; Neoplasms; Polyethylene Glycols; Polysaccharides; Protein Binding | 2014 |
An integrated multifunctional platform based on biotin-doped conducting polymer nanowires for cell capture, release, and electrochemical sensing.
Topics: Antibodies, Immobilized; Biosensing Techniques; Biotin; Cell Line, Tumor; Cell Separation; Electrochemical Techniques; Equipment Design; Humans; Immunohistochemistry; Limit of Detection; Nanowires; Neoplasms; Polymers; Pyrroles | 2014 |
Design, synthesis, and biological evaluation of theranostic vitamin-linker-taxoid conjugates.
Topics: Animals; Biotin; Cells, Cultured; Drug Delivery Systems; Drug Design; Endocytosis; Fibroblasts; Flow Cytometry; Humans; Lung; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Targeted Therapy; Neoplasms; Receptors, Growth Factor; Taxoids; Vitamins | 2015 |
An innovative pre-targeting strategy for tumor cell specific imaging and therapy.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Avidin; Biotin; Drug Delivery Systems; HeLa Cells; Hep G2 Cells; Humans; Mice; Neoplasm Proteins; Neoplasms; Optical Imaging; Receptors, Transferrin | 2015 |
Comparative evaluation of Bis(thiosemicarbazone)- Biotin and Met-ac-TE3A for tumor imaging.
Topics: Acetates; Animals; Biological Assay; Biotin; Cell Line, Tumor; Diagnostic Imaging; Heterocyclic Compounds, 1-Ring; Humans; Hydrogen-Ion Concentration; Mice, Nude; Neoplasms; Potentiometry; Protons; Rabbits; Radiopharmaceuticals; Serum; Thiosemicarbazones; Tissue Distribution | 2016 |
Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin.
Topics: Antineoplastic Agents; Biotin; Biotinylation; Cell Line, Tumor; Humans; Neoplasms; Solid-Phase Synthesis Techniques; Triterpenes | 2015 |
Near-Infrared Light Activation of Proteins Inside Living Cells Enabled by Carbon Nanotube-Mediated Intracellular Delivery.
Topics: Animals; Biotin; Cell Line, Tumor; Cytoplasm; Drug Delivery Systems; Green Fluorescent Proteins; HeLa Cells; Humans; Infrared Rays; Mice; Nanotubes, Carbon; Neoplasms; Proteins; Streptavidin; Xenograft Model Antitumor Assays | 2016 |
Targeted DNA delivery to cancer cells using a biotinylated chitosan carrier.
Topics: Biotin; Chitosan; Gene Transfer Techniques; Green Fluorescent Proteins; HeLa Cells; Humans; Neoplasms; Plasmids | 2017 |
A Method of Targeted Cell Isolation via Glass Surface Functionalization.
Topics: Antibodies; Biotin; Cell Separation; Glass; Heterografts; Humans; Indicators and Reagents; Neoplasms; Streptavidin | 2016 |
A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues.
Topics: Animals; Biotin; Cell Line, Tumor; Fluorescent Dyes; Formaldehyde; Humans; Imaging, Three-Dimensional; Mice; Microscopy, Confocal; Neoplasms; NIH 3T3 Cells; Optical Imaging; Photons; Spectrometry, Fluorescence | 2016 |
A biotin-conjugated glutathione-responsive FRET-based fluorescent probe with a ferrocenyl BODIPY as the dark quencher.
Topics: A549 Cells; Animals; Biotin; Boron Compounds; CHO Cells; Cricetulus; Ferrous Compounds; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Glutathione; Humans; Neoplasms | 2016 |
Graphene quantum dots for cancer targeted drug delivery.
Topics: A549 Cells; Antibiotics, Antineoplastic; Biotin; Cell Survival; Doxorubicin; Drug Delivery Systems; Graphite; Humans; Nanotubes, Carbon; Neoplasms; Quantum Dots | 2017 |
Targeted tumor detection: guidelines for developing biotinylated diagnostics.
Topics: 1-Naphthylamine; Biotin; Biotinylation; Fluorescent Dyes; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Optical Imaging; Quinolones | 2017 |
PBCA-based polymeric microbubbles for molecular imaging and drug delivery.
Topics: Animals; Antibodies; Biotin; Brain; Carotid Arteries; Cell Line, Tumor; Dextrans; Drug Delivery Systems; E-Selectin; Enbucrilate; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Male; Mice, Nude; Microbubbles; Molecular Imaging; Neoplasms; Neovascularization, Pathologic; Rhodamines; Streptavidin; Ultrasonic Waves; Ultrasonography; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
Targeting cancer cells with biotin-dendrimer conjugates.
Topics: Antineoplastic Agents; Biocompatible Materials; Biotin; Dendrimers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; HeLa Cells; Humans; Neoplasms; Polyamines | 2009 |
Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Avidin; Biotin; Diagnostic Imaging; Fluorescence Resonance Energy Transfer; Humans; Mice; Neoplasm Transplantation; Neoplasms; Receptor, ErbB-2; Streptavidin; Trastuzumab | 2009 |
Imaging of HIF-1-active tumor hypoxia using a protein effectively delivered to and specifically stabilized in HIF-1-active tumor cells.
Topics: Animals; Biotin; Cell Hypoxia; Cells, Cultured; Female; Humans; Hypoxia-Inducible Factor 1; Iodine Radioisotopes; Mice; Mice, Inbred C3H; Neoplasms; Radiopharmaceuticals; Recombinant Fusion Proteins; Tissue Distribution | 2009 |
Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery.
Topics: Biological Transport; Biotin; Cell Line; Drug Carriers; Drug Design; Endocytosis; Nanotubes, Carbon; Neoplasms; Substrate Specificity; Taxoids | 2008 |
Identification and ultrastructural imaging of photodynamic therapy-induced microfilaments by atomic force microscopy.
Topics: Actin Cytoskeleton; Amines; Biotin; Cell Line, Tumor; Humans; Light; Microscopy, Atomic Force; Microscopy, Confocal; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins | 2009 |
[Preparation and application of biotinylated anti-AIB1 moniclonal antibody].
Topics: Antibodies, Monoclonal; Biotin; Cell Line, Tumor; Humans; Immunohistochemistry; Neoplasms; Nuclear Receptor Coactivator 3 | 2009 |
Two-step in vivo tumor targeting by biotin-conjugated antibodies and superparamagnetic nanoparticles assessed by magnetic resonance imaging at 1.5 T.
Topics: Antibodies, Monoclonal; Antibodies, Neoplasm; Biotin; CD27 Ligand; Cell Line, Tumor; Dextrans; Ferrosoferric Oxide; Fluorescent Antibody Technique; Humans; Immunoconjugates; Lymphoma; Magnetic Resonance Imaging; Magnetite Nanoparticles; Nanoparticles; Neoplasm Metastasis; Neoplasms; Staining and Labeling; Xenograft Model Antitumor Assays | 2010 |
Selective activation of SHP2 activity by cisplatin revealed by a novel chemical probe-based assay.
Topics: Antibodies; Antineoplastic Agents; Biological Assay; Biotin; Cell Line, Tumor; Cisplatin; Enzyme Activation; Humans; Molecular Probes; Neoplasms; Organophosphates; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases | 2010 |
Fluorescent silica nanoparticles for cancer imaging.
Topics: Antibodies, Neoplasm; Aptamers, Nucleotide; Avidin; Biotin; Carbodiimides; Cyanogen Bromide; Dextrans; Diagnostic Imaging; Disulfides; Drug Delivery Systems; Emulsions; Ethanol; Fluorescence; Nanomedicine; Nanoparticles; Neoplasms; Particle Size; Silicon Dioxide; Surface Properties; Water | 2010 |
The effect of biotin upon para-dimethylaminoazobenzene carcinogenesis.
Topics: Azo Compounds; Biotin; Carcinogenesis; Female; Humans; Neoplasms; p-Dimethylaminoazobenzene; Parity; Vitamin B Complex; Vitamins | 1947 |
Mechanism-based tumor-targeting drug delivery system. Validation of efficient vitamin receptor-mediated endocytosis and drug release.
Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cell Survival; Cytotoxins; Drug Delivery Systems; Endocytosis; Humans; Leukemia; Neoplasms; Taxoids | 2010 |
Preliminary studies on the selective accumulation of vitamin-targeted polymers within tumors.
Topics: Acrylamides; Animals; Biotin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Mice; Microscopy, Fluorescence; Neoplasms; Neoplasms, Experimental; Tissue Distribution; Vitamin B 12; Vitamins | 2011 |
Therapeutic use of avidin is not hampered by antiavidin antibodies in humans.
Topics: Animals; Antibodies; Avidin; Biotin; Humans; Mice; Mice, Inbred BALB C; Models, Animal; Neoplasms; Radioimmunotherapy; Tissue Distribution | 2010 |
Vitamin content of mouse epidermis during methylcholanthrene carcinogenesis; biotin, choline, inositol, rho-aminobenzoic acid, and pyridoxine.
Topics: 4-Aminobenzoic Acid; Acids; Biotin; Carcinogenesis; Choline; Epidermis; Inositol; Methylcholanthrene; Neoplasms; Pyridoxine; Skin Neoplasms; Vitamin B Complex; Vitamins | 1946 |
Adding a clearing agent to pretargeting does not lower the tumor accumulation of the effector as predicted.
Topics: Animal Structures; Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Avidin; Biotin; Cell Line, Tumor; Glycoproteins; Humans; Immunoconjugates; Mice; Mice, Inbred Strains; Mice, Nude; Morpholines; Morpholinos; Neoplasms; Technetium; Tissue Distribution | 2010 |
Cellular localisation of antitumoral 6-alkyl thymoquinones revealed by an alkyne-azide click reaction and the streptavidin-biotin system.
Topics: Alkynes; Antineoplastic Agents; Azides; Benzoquinones; Biotin; Cell Compartmentation; Cell Line, Tumor; Click Chemistry; Female; Fluorescence; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasms; Staining and Labeling; Streptavidin | 2011 |
Lewis X oligosaccharides-heparanase complex targeting to DCs enhance antitumor response in mice.
Topics: Acrylamides; Acrylic Resins; Animals; Biotin; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytotoxicity Tests, Immunologic; Dendritic Cells; Glucuronidase; Interferon-gamma; Lewis Blood Group Antigens; Mice; Mice, Inbred Strains; Neoplasms; Oligosaccharides; Streptavidin; Survival Analysis; T-Lymphocytes, Cytotoxic; Vaccines, Synthetic | 2011 |
Evaluation of two ELISA methods to detect therapeutic anti-IGF1R antibodies in clinical study samples of dalotuzumab.
Topics: Animals; Antibodies, Monoclonal; Biotin; Drug Stability; Enzyme-Linked Immunosorbent Assay; Horseradish Peroxidase; Humans; Mice; Neoplasms; Receptor, IGF Type 1; Streptavidin | 2011 |
Bilayer matrix composed of polycation/DNA complex and sodium alginate gel as a tumor cell catcher.
Topics: Alginates; Animals; Avidin; Biotin; Chlorocebus aethiops; Coculture Techniques; COS Cells; DNA; Drug Carriers; Gels; Glucuronic Acid; HeLa Cells; Hep G2 Cells; Hexuronic Acids; Humans; Luciferases; Molecular Targeted Therapy; Neoplasms; Plasmids; Polyamines; Polyelectrolytes; Polyethyleneimine; Receptors, Transferrin; Static Electricity; Transfection | 2011 |
Comparing the intracellular fate of components within a noncovalent streptavidin nanoparticle with covalent conjugation.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biotin; Cell Line, Tumor; Drug Delivery Systems; Flow Cytometry; Humans; Indicators and Reagents; Indium Radioisotopes; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Streptavidin; Trastuzumab; Vitamin B Complex | 2012 |
Development and evaluation of lipid microbubbles targeted to alpha(v)beta(3)-integrin via biotin-avidin bridge.
Topics: Avidin; Biotin; Cells, Cultured; Contrast Media; Endothelial Cells; Humans; Image Enhancement; Integrin alphaVbeta3; Microbubbles; Neoplasms; Neovascularization, Pathologic | 2012 |
Pretargeting of necrotic tumors with biotinylated hypericin using 123I-labeled avidin: evaluation of a two-step strategy.
Topics: Animals; Anthracenes; Antineoplastic Agents; Avidin; Biotin; Biotinylation; Cell Line, Tumor; Contrast Media; Ethanol; Female; Iodine Radioisotopes; Mice; Mice, Inbred C3H; Necrosis; Neoplasms; Perylene; Tissue Distribution | 2012 |
Novel colorimetric assay of LSD1 activity using gold nanoparticles.
Topics: Antibodies; Avidin; Biotin; Colorimetry; Gold; Histone Demethylases; Histones; Humans; Metal Nanoparticles; Neoplasms; Tranylcypromine | 2012 |
Fluorescence in situ hybridization for cancer-related studies.
Topics: Biotin; Cell Nucleus; Chromosomes, Human; Digoxigenin; DNA Probes; Genetic Markers; Humans; Image Processing, Computer-Assisted; In Situ Hybridization, Fluorescence; Interphase; Metaphase; Neoplasms; Paraffin Embedding; Tissue Array Analysis; Tissue Fixation | 2012 |
Discovery of novel integrin ligands from combinatorial libraries using a multiplex "beads on a bead" approach.
Topics: Biotin; Biotinylation; Cell Adhesion; Cell Line, Tumor; Collagen; Combinatorial Chemistry Techniques; Cytological Techniques; Drug Combinations; Endothelial Cells; Humans; Integrin alphaVbeta3; Laminin; Ligands; Magnetics; Microscopy, Fluorescence; Neoplasms; Oligopeptides; Peptide Library; Peptides; Proteoglycans | 2012 |
Avidin-biotin interaction mediated peptide assemblies as efficient gene delivery vectors for cancer therapy.
Topics: Animals; Avidin; Biotin; Biotinylation; Cell Line, Tumor; Cell-Penetrating Peptides; DNA; Gene Transfer Techniques; Genes, p53; Genetic Therapy; Genetic Vectors; HEK293 Cells; HeLa Cells; Humans; Male; MCF-7 Cells; Mice; Neoplasms; Peptides; Transfection | 2013 |
Production and purification of gallium-66 for preparation of tumor-targeting radiopharmaceuticals.
Topics: Biotin; Gallium Radioisotopes; Humans; Isotope Labeling; Neoplasms; Octreotide; Organometallic Compounds; Radionuclide Imaging; Radiopharmaceuticals; Zinc Isotopes | 2002 |
Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods?
Topics: Antibodies, Monoclonal; Avidin; Biotin; Drug Delivery Systems; Humans; Neoplasms; Radioimmunotherapy; Radiotherapy | 2003 |
Characterization of poultry egg-white avidins and their potential as a tool in pretargeting cancer treatment.
Topics: Animals; Antibodies; Avidin; Biotin; Birds; Neoplasms; Phylogeny; Protein Binding; Sequence Analysis, Protein | 2003 |
Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods?
Topics: Antibodies, Monoclonal; Avidin; Biotin; Drug Delivery Systems; Humans; Neoplasms; Radioimmunotherapy; Radiotherapy | 2003 |
[The influence of heat-induced epitope retrieval on endogenous avidin-binding activity (EABA) and blocking of EABA in immunohistochemistry].
Topics: Animals; Avidin; Biotin; Cells, Cultured; Egg Proteins; Epithelial Cells; Epitopes; Female; Hot Temperature; Humans; Immunohistochemistry; Male; Neoplasms; Rats | 2002 |
Constructs of biotin mimetic peptide with CC49 single-chain Fv designed for tumor pretargeting.
Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Biotin; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Immunoglobulin Fragments; Iodine Isotopes; Mice; Molecular Mimicry; Neoplasm Transplantation; Neoplasms; Radioimmunotherapy; Streptavidin; Substrate Specificity; Time Factors; Tissue Distribution | 2003 |
A new biotin derivative-DOTA conjugate as a candidate for pretargeted diagnosis and therapy of tumors.
Topics: Antineoplastic Agents; Avidin; Biotin; Chelating Agents; Drug Stability; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Neoplasms; Protein Binding; Radiopharmaceuticals; Yttrium | 2003 |
The failure of biotin or oxybiotin to exert a "procarcinogenic" effect on tumor formation by 4-dimethylaminoazobenzene.
Topics: Animals; Biotin; Carcinogens; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene | 1953 |
Validation of a simple avidin-biotin detection method for Helix pomatia lectin (HPA) binding as a prognostic marker in cancer.
Topics: Animals; Avidin; Biomarkers, Tumor; Biosensing Techniques; Biotin; Enzyme-Linked Immunosorbent Assay; Female; Histocytochemistry; Horseradish Peroxidase; Humans; Lectins; Neoplasms; Prognosis; Titrimetry | 2003 |
Aberrant intranuclear localization of biotin, biotin-binding enzymes, and beta-catenin in pregnancy-related endometrium and morule-associated neoplastic lesions.
Topics: beta Catenin; Biotin; Cell Nucleus; Cytoskeletal Proteins; Endometrium; Enzymes; Female; Humans; Immunohistochemistry; Inclusion Bodies; Microscopy, Electron; Neoplasms; Pregnancy; Staining and Labeling; Tissue Distribution; Trans-Activators | 2003 |
Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biotin; Cell Line, Tumor; Cluster Analysis; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Female; Genital Neoplasms, Female; Humans; Immunoglobulin G; Interleukin-8; Luminescent Measurements; Microscopy, Fluorescence; Middle Aged; Multigene Family; Neoplasms; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Platelet-Derived Growth Factor; Protein Array Analysis; Ribonuclease, Pancreatic; Sensitivity and Specificity; Tissue Distribution; Vascular Endothelial Growth Factor A | 2004 |
[Inhibition by vitamin H' of the growth experimental tumors].
Topics: 4-Aminobenzoic Acid; Animals; Biological Phenomena; Biotin; Neoplasms; Neoplasms, Experimental; Physiological Phenomena | 1950 |
Strategies for improving the anti-neoplastic activity of TNF by tumor targeting.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Binding Sites; Biotin; CD13 Antigens; Disease Models, Animal; Ligands; Mice; Neoplasms; Neoplasms, Experimental; Recombinant Fusion Proteins; Tumor Necrosis Factor-alpha | 2004 |
Biotin-rich, optically clear nuclei express estrogen receptor-beta: tumors with morules may develop under the influence of estrogen and aberrant beta-catenin expression.
Topics: Adult; Aged; beta Catenin; Biomarkers, Tumor; Biotin; Cell Nucleus; Cytoskeletal Proteins; Endometrium; Estrogen Receptor beta; Estrogens; Female; Gestational Age; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasms; Pregnancy; Receptors, Estrogen; Trans-Activators | 2004 |
Vitamin B6 and biotin in human cancer tissue.
Topics: Biotin; Humans; Neoplasms; Vitamin B 6; Vitamin B Complex; Vitamins | 1949 |
Highly specific HER2-mediated cellular uptake of antibody-modified nanoparticles in tumour cells.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Specificity; Binding Sites; Biotin; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Delivery Systems; Excipients; Flow Cytometry; Gelatin; Genes, erbB-2; Humans; Immunotoxins; Microscopy, Confocal; Microspheres; Neoplasms; Serum Albumin; Trastuzumab | 2004 |
PHOTOPROBE biotin: an alternative method for labeling archival DNA for comparative genomic hybridization.
Topics: Biotin; Cell Line, Tumor; Chromosome Aberrations; Cytoplasm; DNA; DNA Probes; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; Image Processing, Computer-Assisted; In Situ Hybridization; Karyotyping; Light; Neoplasms; Nucleic Acid Hybridization | 2004 |
Clinicopathological study of the expression of syndecan-1 in invasive breast carcinomas. correlation with extracellular matrix components.
Topics: Avidin; Basement Membrane; Biotin; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cohort Studies; Collagen Type IV; Disease Progression; Disease-Free Survival; Extracellular Matrix; Fibroblast Growth Factor 2; Humans; Immunohistochemistry; Lymphatic Metastasis; Membrane Glycoproteins; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Proteoglycans; Receptors, Progesterone; Streptavidin; Syndecan-1; Syndecans; Tenascin; Time Factors; Tumor Suppressor Protein p53 | 2004 |
Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods.
Topics: Animals; Antibodies, Monoclonal; Avidin; Biotin; Calibration; Cell Line, Tumor; Contrast Media; DNA; DNA, Complementary; Drug Delivery Systems; Female; Gamma Rays; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Mice; Mice, Nude; Models, Biological; Neoplasm Transplantation; Neoplasms; Oligonucleotides; Radioimmunodetection; Radioimmunotherapy; Radioisotopes; Radionuclide Imaging; Recombinant Proteins; Streptavidin; Time Factors; Ultrasonics; Yttrium Radioisotopes | 2005 |
GeneCalling: transcript profiling coupled to a gene database query.
Topics: Animals; Biotin; Computational Biology; Databases, Genetic; Disease Models, Animal; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation; Genetic Techniques; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Oligonucleotides; RNA; RNA, Messenger; Transcription, Genetic | 2006 |
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.
Topics: Animals; Biotin; Cell Line, Tumor; Combinatorial Chemistry Techniques; Databases, Factual; Dipeptides; Drug Design; Humans; Integrin alpha4beta1; Ligands; Mice; Mice, Nude; Molecular Mimicry; Molecular Structure; Mutation; Neoplasm Transplantation; Neoplasms; Peptides; Phenylurea Compounds | 2006 |
PRINS for the detection of gene deletions in cancer.
Topics: Biotin; Bone Marrow Cells; Cells, Cultured; DNA, Neoplasm; Gene Deletion; Humans; Microscopy, Fluorescence; Neoplasms; Primed In Situ Labeling | 2006 |
Biotinylated thermoresponsive micelle self-assembled from double-hydrophilic block copolymer for drug delivery and tumor target.
Topics: Acrylic Resins; Biotin; Biotinylation; Cell Line; Cell Survival; Drug Carriers; Humans; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Confocal; Microscopy, Electron, Transmission; Molecular Structure; Neoplasms; Polyethylene Glycols; Sensitivity and Specificity; Temperature; Water | 2008 |
CD10 is a characteristic marker of tumours forming morules with biotin-rich, optically clear nuclei that occur in different organs.
Topics: Adenocarcinoma, Papillary; Antigens, Neoplasm; Biomarkers, Tumor; Biotin; Cell Nucleus; Female; Humans; Lung Neoplasms; Metaplasia; Neoplasms; Neprilysin; Pancreatic Neoplasms; Pulmonary Blastoma; Thyroid Neoplasms | 2008 |
A simplified, sensitive immunohistochemical detection system employing signal amplification based on fluorescyl-tyramide/antifluorescein antibody reaction: its application to pathologic testing and research.
Topics: Animals; Antibodies; Antigens, Neoplasm; Biotin; Humans; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasms; Paraffin Embedding; Sensitivity and Specificity; Tyramine | 2008 |
Differential growth of malignant and nonmalignant tissues in rats bearing hepatoma 31; influence of dietary protein, riboflavin, and biotin.
Topics: Animals; Biotin; Carcinoma, Hepatocellular; Dietary Proteins; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Rats; Riboflavin | 1949 |
[Advances in immunological diagnosis: monoclonal antibodies. The biotin-avidin system].
Topics: Animals; Antibodies; Antibodies, Monoclonal; Avidin; Biotin; Fluorescent Antibody Technique; Humans; Hybridomas; Infections; Lymphocytes; Mice; Neoplasms | 1984 |
[Use of immunocytochemistry in practical diagnosis by the pathologist. Areas of use--methods--cost planning].
Topics: Alkaline Phosphatase; Antibodies, Monoclonal; Avidin; Biotin; Cost-Benefit Analysis; Diagnosis, Differential; Fluorescent Antibody Technique; Histological Techniques; Humans; Immunochemistry; Immunoenzyme Techniques; Immunoglobulins; Lectins; Neoplasms; Pathology | 1984 |
Purging tumor cells from bone marrow or peripheral blood using avidin-biotin immunoadsorption.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, CD34; Antigens, Differentiation, B-Lymphocyte; Avidin; B-Lymphocytes; Biotin; Blood Cells; Bone Marrow Purging; Breast Neoplasms; Female; Flow Cytometry; Humans; Immunosorbent Techniques; Mice; Models, Biological; Neoplasms; Rats; Tumor Cells, Cultured | 1994 |
The in vivo uses of streptavidin and biotin: a short progress report.
Topics: Antibodies, Monoclonal; Bacterial Proteins; Biotin; Humans; Neoplasms; Radioimmunodetection; Streptavidin | 1994 |
Detection of apoptosis-associated DNA strand breaks in fine-needle aspiration biopsies by in situ end labeling of fragmented DNA.
Topics: Aneuploidy; Apoptosis; Biopsy, Needle; Biotin; Diploidy; DNA Damage; DNA Nucleotidylexotransferase; DNA, Neoplasm; Flow Cytometry; Humans; Neoplasms | 1994 |
Detection of quantitative polymerase chain reaction products by hybridization on magnetic support with 125I-radiolabeled probes: quantification of c-myc copy numbers.
Topics: Bacterial Proteins; Base Sequence; Biotin; DNA Probes; Genes, myc; Humans; Iodine Radioisotopes; Magnetics; Molecular Sequence Data; Neoplasms; Nucleic Acid Hybridization; Polymerase Chain Reaction; Reference Standards; Sensitivity and Specificity; Streptavidin; Tumor Cells, Cultured | 1993 |
Rapid tumor imaging by active background reduction using biotin-bearing liposomes and avidin.
Topics: Animals; Avidin; Biotin; Drug Carriers; Gallium Radioisotopes; Indium Radioisotopes; Liposomes; Male; Mice; Mononuclear Phagocyte System; Neoplasms; Radionuclide Imaging; Sarcoma 180; Time Factors | 1994 |
Localization of EGF receptors in frozen tissue sections by antibody and biotinylated EGF-based techniques.
Topics: Animals; Antibodies, Monoclonal; Biotin; Epidermal Growth Factor; ErbB Receptors; Female; Frozen Sections; Humans; Immunoenzyme Techniques; Ligands; Liver; Male; Mice; Microtomy; Neoplasms; Rats; Sensitivity and Specificity; Skin | 1994 |
A distributed pharmacokinetic model of two-step imaging and treatment protocols: application to streptavidin-conjugated monoclonal antibodies and radiolabeled biotin.
Topics: Bacterial Proteins; Biotin; Humans; Indium Radioisotopes; Models, Theoretical; Neoplasms; Pentetic Acid; Radioimmunodetection; Radioimmunotherapy; Streptavidin; Tissue Distribution | 1993 |
Gene mapping by FISH.
Topics: Biotin; Chromatin; Chromosome Mapping; Digoxigenin; DNA; DNA Probes; Humans; In Situ Hybridization, Fluorescence; Neoplasms; Polymerase Chain Reaction; Restriction Mapping | 1997 |
[Gene delivery into human cancer cells via transferrin receptor].
Topics: Adenoviridae; Biotin; DNA; Drug Delivery Systems; Genetic Therapy; Genetic Vectors; Glycerol; Humans; Liposomes; Neoplasms; Polylysine; Receptors, Transferrin | 1998 |
Tumor targeting with biotinylated tumor necrosis factor alpha: structure-activity relationships and mechanism of action on avidin pretargeted tumor cells.
Topics: Animals; Avidin; Binding Sites; Biotin; Humans; Melanoma; Mice; Neoplasms; Receptors, Tumor Necrosis Factor; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 1998 |
Immunodiagnosis of childhood malignancies.
Topics: Adolescent; Avidin; Biomarkers, Tumor; Biotin; Child; Child, Preschool; Humans; Immunoenzyme Techniques; Immunohistochemistry; Intermediate Filament Proteins; Medical Oncology; Neoplasms | 1999 |
Transplantation of stem cells enriched by immunoadsorption.
Topics: Animals; Antigens, CD; Antigens, CD34; Avidin; Biotin; Bone Marrow Purging; Bone Marrow Transplantation; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosorbent Techniques; Neoplasms; Papio | 1992 |
Labelling of tumour cells with a biotinylated inhibitor of a cell surface protease.
Topics: Affinity Labels; Agmatine; Animals; Biotin; Carcinoma, Squamous Cell; Cell Membrane; Endopeptidases; Humans; Leukemia, Experimental; Male; Mouth Neoplasms; Neoplasms; Prostatic Neoplasms; Protease Inhibitors; Rats | 1991 |
A simple method for isolation of DNA from formalin-fixed paraffin-embedded samples for PCR.
Topics: Base Sequence; Biopsy; Biotin; DNA, Neoplasm; DNA, Single-Stranded; Genes, myc; Humans; Molecular Sequence Data; Neoplasms; Polymerase Chain Reaction; Tissue Embedding; Tissue Preservation | 1991 |
Detection of chromogranins A and B in endocrine tissues with radioactive and biotinylated oligonucleotide probes.
Topics: Biotin; Blotting, Northern; Chromogranins; Endocrine Glands; Endocrine System Diseases; Humans; Neoplasms; Nerve Tissue Proteins; Nucleic Acid Hybridization; Oligonucleotide Probes; RNA, Messenger; RNA, Neoplasm; Sulfur Radioisotopes | 1990 |
Combined immunoreaction and Papanicolaou's stain on cytological smears.
Topics: Antibodies, Monoclonal; Avidin; Biotin; Chymotrypsin; Cytodiagnosis; Cytological Techniques; Epithelium; Histocytochemistry; Humans; Immunologic Techniques; Keratins; Neoplasms; Pleural Effusion; Staining and Labeling | 1986 |
Avidin-biotin-peroxidase-antiperoxidase (ABPAP) complex. An immunocytochemical method with enhanced sensitivity.
Topics: Antibodies, Monoclonal; Antigens, Surface; Avidin; Biotin; Female; Histocytochemistry; Humans; Immunoenzyme Techniques; Keratins; Male; Neoplasms | 1987 |
Immunostaining for leukocyte common antigen using an amplified avidin-biotin-peroxidase complex method and paraffin sections. A study of 735 hematopoietic and nonhematopoietic human neoplasms.
Topics: Antibodies, Monoclonal; Avidin; Biotin; Dysgerminoma; Histocompatibility Antigens; Histological Techniques; Hodgkin Disease; Humans; Leukocyte Common Antigens; Lymphoma; Lymphoma, Non-Hodgkin; Male; Neoplasms; Peroxidases; Staining and Labeling; Testicular Neoplasms | 1987 |
Application of a quick immunoenzymatic labeling as an adjunct to frozen-section diagnosis.
Topics: Avidin; Biotin; Frozen Sections; Immunoenzyme Techniques; Microtomy; Neoplasms; Staining and Labeling | 1989 |
[The chemical modification of immunoglobulins for accelerating their elimination from the blood flow during radioimmunodiagnosis].
Topics: Antibodies, Neoplasm; Antibody Specificity; Avidin; Biotin; Humans; Immunoglobulins; Neoplasms; Radioimmunoassay | 1989 |
Immunohistochemical phenotyping of human solid tumors with monoclonal antibodies in devising biotherapeutic strategies.
Topics: Adult; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Avidin; Biotin; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Cross Reactions; Horseradish Peroxidase; Humans; Immunoenzyme Techniques; Melanoma; Mice; Neoplasms; Phenotype | 1989 |
Immunohistochemical analysis of nerve growth factor receptor expression in normal and malignant human tissues.
Topics: Aging; Antibodies, Monoclonal; Avidin; Biotin; Brain Chemistry; Epithelium; Fetus; Humans; Immunoenzyme Techniques; Immunohistochemistry; Lymphoid Tissue; Mesoderm; Neoplasms; Peripheral Nerves; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Spinal Cord; Tissue Distribution | 1988 |
Detection of extracellular matrix antigens (fibronectin, laminin, type IV in collagen) in paraffin embedded sections by avidin-biotin-peroxidase complex labelling.
Topics: Avidin; Biotin; Collagen; Extracellular Matrix; Fibronectins; Histocytochemistry; Histological Techniques; Humans; Immunochemistry; Isoenzymes; Laminin; Neoplasms; Peroxidase; Peroxidases | 1986 |
[Detection of mannan from sera of cancer patients with and without candidiasis by biotin-streptavidin enzyme immunoassay].
Topics: Animals; Antigens, Fungal; Bacterial Proteins; Biotin; Candidiasis; Female; Immunoenzyme Techniques; Male; Mannans; Mice; Neoplasms; Streptavidin | 1987 |
Demonstration of antigenemia in patients with invasive aspergillosis by biotin-streptavidin enzyme-linked immunosorbent assay.
Topics: Adult; Antigens, Fungal; Aspergillosis; Bacterial Proteins; Biotin; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Humans; Neoplasms; Streptavidin | 1988 |
Iodine-131 and indium-111 labelled avidin and streptavidin for pre-targetted immunoscintigraphy with biotinylated anti-tumour monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Avidin; Bacterial Proteins; Biotin; Indium Radioisotopes; Iodine Radioisotopes; Mice; Neoplasms; Radionuclide Imaging; Streptavidin | 1988 |
[Egg white and cancer].
Topics: Animals; Biotin; Breast Neoplasms; Drug Synergism; Female; Humans; Laryngeal Neoplasms; Male; Neoplasm Metastasis; Neoplasms; Ovalbumin; Pharyngeal Neoplasms; Swine | 1973 |