Page last updated: 2024-08-25

bilobalide and Brain Ischemia

bilobalide has been researched along with Brain Ischemia in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (63.64)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eckert, GP; Hagl, S; Klein, J; Schwarzkopf, TM1
Liu, JX; Song, WT; Xu, L; Yao, MJ; Zheng, YQ1
Jiang, M; Li, J; Liu, W; Liu, Y; Luo, C; Mo, Z; Peng, J; Peng, Q; Yung, KK1
Biswal, S; Christen, Y; Doré, S; Saleem, S; Zhuang, H1
Hartmann, J; Kiewert, C; Klein, J; Lang, D; Mdzinarishvili, A; Schwarzkopf, TM; Sumbria, R1
Chandrasekaran, K; Chinopoulos, C; Drieu, K; Fiskum, G; Mehrabian, Z; Spinnewyn, B2
Ahlemeyer, B; Krieglstein, J1
Hillert, M; Kiewert, C; Klein, J; Kumar, V; Mdzinarishvili, A1
Hartmann, J; Hildmann, O; Hillert, M; Kiewert, C; Klein, J; Kumar, V1
Chandrasekaran, K; Drieu, K; Fiskum, G; Mehrabian, Z; Spinnewyn, B1

Reviews

1 review(s) available for bilobalide and Brain Ischemia

ArticleYear
Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease.
    Pharmacopsychiatry, 2003, Volume: 36 Suppl 1

    Topics: Alzheimer Disease; Animals; Apoptosis; Brain Ischemia; Cells, Cultured; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Flavones; Flavonoids; Furans; Ginkgo biloba; Ginkgolides; Glutamic Acid; Humans; Hypoxia; Lactones; Neurons; Neuroprotective Agents; Plant Extracts; Time Factors

2003

Other Studies

10 other study(ies) available for bilobalide and Brain Ischemia

ArticleYear
Neuroprotection by bilobalide in ischemia: improvement of mitochondrial function.
    Die Pharmazie, 2013, Volume: 68, Issue:7

    Topics: Animals; Brain Ischemia; Cyclopentanes; Female; Furans; Ginkgolides; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Mice; Microdialysis; Mitochondria; Neostriatum; Neuroprotective Agents; Oxygen Consumption; Permeability

2013
[Study on effect of weinaokang and bilobalide on autophagy and neurogenesis induced by focal cerebral ischemia reperfusion].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:13

    Topics: Animals; Autophagy; Brain Ischemia; Cyclopentanes; Drugs, Chinese Herbal; Furans; Ginkgolides; Male; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2013
Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation.
    Journal of neuroinflammation, 2014, Sep-26, Volume: 11

    Topics: Animals; Brain Ischemia; Cyclopentanes; Disease Models, Animal; Down-Regulation; Enzyme Activation; Furans; Ginkgolides; Male; MAP Kinase Signaling System; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2014
Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.
    Stroke, 2008, Volume: 39, Issue:12

    Topics: Animals; Antioxidants; Brain Damage, Chronic; Brain Ischemia; Cells, Cultured; Cerebrovascular Circulation; Cyclopentanes; Drug Evaluation, Preclinical; Enzyme Induction; Excitatory Amino Acid Antagonists; Furans; Ginkgo biloba; Ginkgolides; Glutamic Acid; Heme Oxygenase-1; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Plant Extracts; Reperfusion Injury; Response Elements

2008
Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo.
    Brain research, 2011, Nov-24, Volume: 1425

    Topics: Animals; Brain; Brain Ischemia; Cyclopentanes; Dose-Response Relationship, Drug; Female; Furans; Ginkgolides; Glutamic Acid; Mice; Microdialysis; Neuroprotective Agents

2011
Bilobalide, a component of the Ginkgo biloba extract (EGb 761), protects against neuronal death in global brain ischemia and in glutamate-induced excitotoxicity.
    Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48, Issue:6

    Topics: Administration, Oral; Animals; Brain Ischemia; Cell Death; Cerebellum; Cyclopentanes; Diterpenes; Electron Transport Complex IV; Furans; Gerbillinae; Ginkgo biloba; Ginkgolides; Glutamic Acid; Hippocampus; Male; Neurons; Neuroprotective Agents; Plant Extracts; Reperfusion Injury

2002
Neuroprotective effects of bilobalide, a component of Ginkgo biloba extract (EGb 761) in global brain ischemia and in excitotoxicity-induced neuronal death.
    Pharmacopsychiatry, 2003, Volume: 36 Suppl 1

    Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cyclopentanes; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Electron Transport Complex IV; Furans; Gerbillinae; Ginkgo biloba; Ginkgolides; Glutamic Acid; Glycine; Hippocampus; In Situ Hybridization; In Vitro Techniques; Inhibitory Concentration 50; Male; Membrane Proteins; Plant Extracts; Rats; Reperfusion; RNA, Messenger; Saccharomyces cerevisiae Proteins; Trauma, Nervous System

2003
Bilobalide prevents ischemia-induced edema formation in vitro and in vivo.
    Neuroscience, 2007, Jan-05, Volume: 144, Issue:1

    Topics: Animals; Body Water; Brain Chemistry; Brain Edema; Brain Ischemia; Cell Death; Cyclopentanes; Furans; Ginkgolides; Hippocampus; In Vitro Techniques; Male; Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Stroke; Water Intoxication

2007
Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide.
    Brain research, 2008, Mar-27, Volume: 1201

    Topics: Animals; Binding Sites; Binding, Competitive; Brain Edema; Brain Ischemia; Chlorides; Choline; Cyclopentanes; Excitatory Amino Acid Agonists; Furans; Ginkgolides; Glycine; Hippocampus; Male; Membrane Lipids; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2008
Neuroprotective effects of bilobalide, a component of the Ginkgo biloba extract (EGb 761), in gerbil global brain ischemia.
    Brain research, 2001, Dec-20, Volume: 922, Issue:2

    Topics: Animals; Brain; Brain Ischemia; Cell Count; Cell Death; Cyclopentanes; Cytochrome-c Oxidase Deficiency; Diterpenes; DNA, Mitochondrial; Electron Transport Complex IV; Energy Metabolism; Furans; Gene Expression Regulation, Enzymologic; Gerbillinae; Ginkgo biloba; Ginkgolides; Hippocampus; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Phosphorylation; Plant Extracts; Reperfusion Injury; RNA, Messenger

2001