bilirubin-diglucuronide has been researched along with Jaundice* in 2 studies
1 review(s) available for bilirubin-diglucuronide and Jaundice
| Article | Year |
|---|---|
Bile changes after liver surgery: experimental and clinical lessons for future applications.
The aim of this review is to summarize the available evidence for changes in bile composition following liver surgery and assess their use in predicting post-operative complications.. A literature search was undertaken for all studies focusing on bile composition, bile volume and analysis. Articles were selected from MEDLINE, Embase and the Cochrane Central Register of Controlled Trials databases up to May 2009.. Low values of pre-operative bilirubin diglucuronide predict reduced post-operative liver function and the occurrence of jaundice. Low concentrations of hepatocyte growth factor and interleukin-6 in bile following surgery are associated with the subsequent development of liver failure and are probably surrogate markers for situations where the resultant hepatic regeneration is inadequate.. Analysis of the composition and quality of bile is probably underused as a tool for the pre-operative screening and early post-operative monitoring of patients at high risk of developing liver failure following major hepatobiliary procedures. Topics: Bile; Bilirubin; Hepatocyte Growth Factor; Humans; Interleukin-6; Jaundice; Liver; Liver Failure; Liver Regeneration; Monitoring, Physiologic; Postoperative Period | 2010 |
1 other study(ies) available for bilirubin-diglucuronide and Jaundice
| Article | Year |
|---|---|
Toxicity of bilirubin and bilirubin diglucuronide to rat tissue culture fibroblasts.
The effects of obstructive and non-obstructive jaundice on rat tissue culture fibroblasts have been compared. Tissue culture fibroblasts were grown in medium containing unconjugated bilirubin and medium containing conjugated bilirubin (bilirubin diglucuronide). The addition of bilirubin to the culture medium caused morphological changes in the fibroblasts and significantly decreased their rate of multiplication. The addition of bilirubin diglucuronide had no effect. As the fibroblast plays an important role in wound healing, patients with obstructive jaundice (where surgery is most frequently required) may be less likely to undergo wound failure than patients with non-obstructive jaundice. Topics: Animals; Bilirubin; Culture Techniques; Fibroblasts; Jaundice; Rats; Wound Healing | 1988 |