biguanides has been researched along with Tooth Discoloration in 37 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Tooth Discoloration: Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary purpose of this study was to determine the safety and effectiveness of alexidine in the control of plaque and gingivitis in humans." | 9.04 | Effects of an alexidine mouthwash on dental plaque and gingivitis in humans over a six-month period. ( Finn, SB; Jamison, HC; Weatherford, TW, 1977) |
| "05% chlorhexidine gluconate solutions used on the toothbrush subsequent to scaling were for at least 45 days able to maintain plaque and gingivitis scores lower than those obtained 14 days after scaling and oral hygiene instruction." | 9.04 | Effect of toothbrushing with different concentrations of chlorhexidine on the development of dental plaque and gingivitis. ( Bay, LM, 1978) |
| "The primary purpose of this study was to determine the safety and effectiveness of alexidine in the control of plaque and gingivitis in humans." | 5.04 | Effects of an alexidine mouthwash on dental plaque and gingivitis in humans over a six-month period. ( Finn, SB; Jamison, HC; Weatherford, TW, 1977) |
| "05% chlorhexidine gluconate solutions used on the toothbrush subsequent to scaling were for at least 45 days able to maintain plaque and gingivitis scores lower than those obtained 14 days after scaling and oral hygiene instruction." | 5.04 | Effect of toothbrushing with different concentrations of chlorhexidine on the development of dental plaque and gingivitis. ( Bay, LM, 1978) |
| "Hibitane is a valuable drug in the treatment of denture stomatitis when used as a denture disinfectant." | 2.64 | Hibitane in the treatment of oral candidiasis. ( Budtz-Jörgensen, E, 1977) |
| " Only one significant adverse effect has been identified during medical use, namely, the production of sensorineural deafness after direct instillation into the middle ear, a property shared by several commonly used antiseptics." | 1.26 | Safety of Hibitane. II. Human experience. ( Rushton, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moran, J | 1 |
| Addy, M | 2 |
| Roberts, WR | 1 |
| Löe, H | 3 |
| Schiött, CR | 1 |
| Karring, G | 1 |
| Karring, T | 1 |
| Storhaug, K | 1 |
| Weatherford, TW | 1 |
| Finn, SB | 1 |
| Jamison, HC | 1 |
| Carlson, HC | 1 |
| Porter, K | 1 |
| Alms, TH | 1 |
| Rushton, A | 1 |
| Gjermo, P | 10 |
| Curtis, SN | 1 |
| Dooley, CL | 1 |
| Nordbøo, H | 1 |
| Hoyos, DF | 1 |
| Murray, JJ | 1 |
| Shaw, L | 1 |
| Svantun, B | 1 |
| Eriksen, HM | 4 |
| Rolla, G | 3 |
| Spolsky, VW | 1 |
| Forsythe, AB | 1 |
| Budtz-Jörgensen, E | 1 |
| Bay, LM | 1 |
| Bain, MJ | 1 |
| Strahan, JD | 1 |
| Formicola, AJ | 1 |
| Deasy, MJ | 1 |
| Johnson, DH | 1 |
| Howe, EE | 1 |
| Lennon, MA | 1 |
| Davies, RM | 1 |
| Bassiouny, MA | 1 |
| Grant, AA | 1 |
| Hansen, F | 1 |
| Johansen, JR | 2 |
| Plüss, E | 1 |
| Hamp, SE | 1 |
| Flotra, L | 2 |
| Heyden, G | 1 |
| Jensen, SB | 2 |
| Kobylańska, M | 1 |
| Bergenholtz, A | 1 |
| Hänström, L | 1 |
| Waerhaug, J | 1 |
| Nordbö, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Evaluation of a Mouthwash Containing Malva Sylvestris Extract and Its Role in Reducing Oral Biofilm and Gingival Inflammation. A Randomized, Triple Masked Clinical Trial.[NCT05138484] | Phase 3 | 54 participants (Actual) | Interventional | 2017-10-20 | Completed | ||
| Comparative Evaluation of the Plaque Removal Efficacy and Patient Acceptability of the Knotted Floss Technique With Conventional Flossing Technique and Interdental Brushing in Type II Gingival Embrasures - A Clinical Crossover Study[NCT03414073] | 45 participants (Actual) | Interventional | 2018-02-05 | Completed | |||
| Comparing the Effect of 0,06 % -, 0,12 % and 0,2 % Chlorhexidine on Plaque, Bleeding and Side Effects in an Experimental Gingivitis Model. A Parallel, Double Masked, Randomized, Placebo-controlled Clinical Trial[NCT02911766] | Phase 4 | 59 participants (Anticipated) | Interventional | 2016-11-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for biguanides and Tooth Discoloration
| Article | Year |
|---|---|
Chlorhexidine in dental practice.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Candida albicans; Candidiasis, Oral; Chlorobenzen | 1974 |
Does chlorhexidine have a place in the prophylaxis of dental diseases?
Topics: Absorption; Animals; Anti-Infective Agents, Local; Biguanides; Humans; Mouth Diseases; Mouth Mucosa; | 1973 |
Studies on the effect and mode of action of chlorhexidine in dental plaque inhibition.
Topics: Administration, Topical; Biguanides; Carbon Radioisotopes; Clinical Trials as Topic; Dental Plaque; | 1974 |
[Chemical control of dental plaque].
Topics: Anti-Bacterial Agents; Biguanides; Dental Plaque; Dextranase; Drug Resistance, Microbial; Gingival D | 1971 |
17 trials available for biguanides and Tooth Discoloration
| Article | Year |
|---|---|
Comparison of the bisbiguanide antiseptics alexidine and chlorhexidine. II. Clinical and in vitro staining properties.
Topics: Biguanides; Chlorhexidine; Color; Humans; In Vitro Techniques; Mouthwashes; Random Allocation; Tea; | 1981 |
Two years oral use of chlorhexidine in man. I. General design and clinical effects.
Topics: Administration, Oral; Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Calculus; D | 1976 |
Two years oral use of chlorhexidine in man. I. General design and clinical effects.
Topics: Administration, Oral; Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Calculus; D | 1976 |
Two years oral use of chlorhexidine in man. I. General design and clinical effects.
Topics: Administration, Oral; Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Calculus; D | 1976 |
Two years oral use of chlorhexidine in man. I. General design and clinical effects.
Topics: Administration, Oral; Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Calculus; D | 1976 |
Effects of an alexidine mouthwash on dental plaque and gingivitis in humans over a six-month period.
Topics: Adolescent; Adult; Aged; Biguanides; Dental Plaque; Drug Evaluation; Female; Gingivitis; Humans; Mal | 1977 |
The effect of chlorhexidine gel on plaque and gingivitis in children.
Topics: Adolescent; Biguanides; Child; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Female; Gels; | 1977 |
A comparison of the plaque-inhibiting effect of stannous fluoride and chlorhexidine.
Topics: Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Double-Blind Method; Female; Flu | 1977 |
Effects of alexidine.2HCL mouthwash on plaque and gingivitis after six months.
Topics: Adult; Biguanides; Clinical Trials as Topic; Color; Composite Resins; Dental Plaque; Double-Blind Me | 1977 |
Hibitane in the treatment of oral candidiasis.
Topics: Biguanides; Candida albicans; Candidiasis, Oral; Chlorhexidine; Clinical Trials as Topic; Denture, C | 1977 |
Effect of toothbrushing with different concentrations of chlorhexidine on the development of dental plaque and gingivitis.
Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Dental Scaling; Double-Bl | 1978 |
The effect of a 1% chlorhexidine gel in the initial therapy of chronic periodontal disease.
Topics: Adolescent; Adult; Biguanides; Chlorhexidine; Chronic Disease; Clinical Trials as Topic; Dental Plaq | 1978 |
Tooth staining effects of an alexidine mouthwash.
Topics: Adolescent; Adult; Aged; Biguanides; Clinical Trials as Topic; Coffee; Dental Plaque; Dental Prophyl | 1979 |
A short-term evaluation of a chlorhexidine gel on plaque deposits and gingival status.
Topics: Adolescent; Adult; Analysis of Variance; Biguanides; Chlorhexidine; Dental Plaque; Dentifrices; Gels | 1975 |
The toothbrush application of chlorhexidine. A clinical trial.
Topics: Administration, Topical; Adult; Aged; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Ca | 1975 |
The effect of a chlorhexidine-containing gel on oral cleanliness and gingival health in young adults.
Topics: Adolescent; Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Female; Gels; | 1975 |
Effect of 2-years' use of chlorhexidine-containing dentifrices on plaque, gingivitis, and caries.
Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Caries; Dental Plaque; Dentifrice | 1975 |
Different modes of chlorhexidine application and related local side effects.
Topics: Biguanides; Clinical Trials as Topic; Dental Plaque; Dentifrices; Gingival Diseases; Humans; Mouth D | 1973 |
Incidence of stained tooth surfaces in students using chlorhexidine-containing dentifrices.
Topics: Biguanides; Coffee; Dentifrices; Humans; Incisor; Mandible; Placebos; Smoking; Tea; Time Factors; To | 1973 |
Studies on the effect and mode of action of chlorhexidine in dental plaque inhibition.
Topics: Administration, Topical; Biguanides; Carbon Radioisotopes; Clinical Trials as Topic; Dental Plaque; | 1974 |
17 other studies available for biguanides and Tooth Discoloration
| Article | Year |
|---|---|
The effect of surface adsorption and staining reactions on the antimicrobial properties of some cationic antiseptic mouthwashes.
Topics: Adsorption; Anti-Infective Agents, Local; Bacteria; Biguanides; Cetylpyridinium; Chlorhexidine; Dent | 1984 |
Hibitane in oral disease in handicapped patients.
Topics: Biguanides; Chlorhexidine; Dental Plaque; Disabled Persons; Drug Evaluation; Humans; Mouthwashes; Ti | 1977 |
The effect of an alexidine mouthwash on dental plaque and gingivitis.
Topics: Adolescent; Adult; Aged; Biguanides; Color; Dental Plaque; Gingivitis; Humans; Middle Aged; Mouthwas | 1977 |
Safety of Hibitane. II. Human experience.
Topics: Administration, Oral; Biguanides; Chlorhexidine; Dental Plaque; Drug Evaluation; Humans; Mouthwashes | 1977 |
Hibitane in periodontal disease.
Topics: Biguanides; Chlorhexidine; Dental Plaque; Gingivitis; Humans; Periodontal Diseases; Time Factors; To | 1977 |
Cariostatic activity of (1,6-bis-[2-ethylhexylbiguanido]-hexane) in conventional rats.
Topics: Animals; Biguanides; Cariostatic Agents; Chlorhexidine; Chlorides; Dental Caries; Diet, Cariogenic; | 1979 |
Ability of chlorhexidine and benzalkonium chloride to catalyze browning reactions in vitro.
Topics: Benzalkonium Compounds; Biguanides; Catalysis; Chlorhexidine; Dental Deposits; Humans; Tooth Discolo | 1979 |
Plaque inhibition and staining by hibitane and vantocil.
Topics: Adult; Biguanides; Chlorhexidine; Dental Plaque; Female; Humans; Male; Placebos; Tooth Discoloration | 1975 |
Long term effect of chlorhexidine on developing gingivitis in the Beagle dog.
Topics: Animals; Biguanides; Dental Calculus; Dental Plaque; Dogs; Gingivitis; Mouthwashes; Time Factors; To | 1973 |
Relation between locally high concentration of chlorhexidine and staining as seen in the clinic.
Topics: Autoradiography; Biguanides; Carbon Isotopes; Coloring Agents; Histocytochemistry; Humans; Tooth Dis | 1973 |
[Studies on new possibilities in plaque removable].
Topics: Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dental Prophylaxis; Dextranase; Gingivitis; | 1972 |
[Chlorhexidine for removal of dental plaque].
Topics: Biguanides; Dental Plaque; Humans; Mouth Mucosa; Mouthwashes; Taste; Tooth Discoloration | 1972 |
[Studies on new possibilities in plaque removal].
Topics: Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dental Prophylaxis; Dextranase; Gingivitis; | 1972 |
The plaque-inhibiting effect of hexetidine (Oraldene)-mouthwash compared to that of chlorhexidine.
Topics: Adult; Biguanides; Dental Plaque; Dental Prophylaxis; Female; Gingivitis; Hexetidine; Humans; Male; | 1974 |
Side effects of chlorhexidine mouth washes.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Humans; Male; Mouth Diseases; Mouth Mucosa; Mouthwa | 1971 |
The plaque-inhibiting effect of chlorhexidine-containing dentifrices.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dentifrices; Disinfectants; Humans; | 1971 |
Discoloration of human teeth by a combination of chlorhexidine and aldehydes or ketones in vitro.
Topics: Acetaldehyde; Acetoacetates; Acetone; Aldehydes; Biguanides; Dental Cementum; Dental Enamel; Dextran | 1971 |