Page last updated: 2024-11-08

biguanides and Smear Layer

biguanides has been researched along with Smear Layer in 13 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Smear Layer: Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.

Research Excerpts

ExcerptRelevanceReference
"The smear layer was evaluated under × 500, × 1000, and × 2000 magnifications."1.42Influence of diode laser application on the efficiency of QMiX and EDTA solutions in removing smear layer. ( Çiçek, E; Koçak, MM; Koçak, S; Sağlam, BC; Türker, SA, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldasso, FER1
Roleto, L1
Silva, VDD1
Morgental, RD1
Kopper, PMP1
Ballal, NV1
Sona, M1
Tay, FR3
Nogo-Živanović, D1
Kanjevac, T1
Bjelović, L1
Ristić, V1
Tanasković, I1
Elnaghy, AM1
Wang, Z2
Shen, Y3
Haapasalo, M3
Niu, LN1
Luo, XJ1
Li, GH1
Bortoluzzi, EA1
Mao, J1
Chen, JH1
Gutmann, JL2
Pashley, DH1
Jardine, AP1
Rosa, RA1
Santini, MF1
Wagner, M1
Só, MV1
Kuga, MC1
Pereira, JR1
Kopper, PM1
Koçak, S1
Çiçek, E1
Sağlam, BC1
Koçak, MM1
Türker, SA1
Arslan, D1
Guneser, MB1
Dincer, AN1
Kustarci, A1
Er, K1
Siso, SH1
Dai, L1
Khechen, K1
Khan, S1
Gillen, B1
Loushine, BA1
Wimmer, CE1
Pashley, D1
Pai, S1
Thomas, MS1
Stojicic, S1
Qian, W1
Johnson, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of QMix 2-in-1 as Final Irrigation Protocol on Periapical Healing After Single-visit Root Canal Treatment: a Randomized Controlled Trial[NCT04348578]60 participants (Actual)Interventional2017-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for biguanides and Smear Layer

ArticleYear
Effect of final irrigation protocols on microhardness reduction and erosion of root canal dentin.
    Brazilian oral research, 2017, May-15, Volume: 31

    Topics: Biguanides; Citric Acid; Dental Pulp Cavity; Dentin; Edetic Acid; Hardness Tests; Humans; Materials

2017
Effects of smear layer removal agents on the physical properties and microstructure of mineral trioxide aggregate cement.
    Journal of dentistry, 2017, Volume: 66

    Topics: Aluminum Compounds; Biguanides; Calcium Compounds; Compressive Strength; Dental Cements; Drug Combin

2017
The effect of final irrigation with MTAD, QMix, and EDTA on smear layer removal and mineral content of root canal dentin.
    Microscopy research and technique, 2019, Volume: 82, Issue:6

    Topics: Biguanides; Citric Acid; Dental Pulp Cavity; Dentin; Doxycycline; Edetic Acid; Humans; Microscopy, E

2019
Effect of QMix irrigant on bond strength of glass fibre posts to root dentine.
    International endodontic journal, 2014, Volume: 47, Issue:3

    Topics: Adhesiveness; Biguanides; Chlorhexidine; Dental Bonding; Dental Stress Analysis; Dentin; Edetic Acid

2014
Effect of smear layer against disinfection protocols on Enterococcus faecalis-infected dentin.
    Journal of endodontics, 2013, Volume: 39, Issue:11

    Topics: Bacterial Load; Bacteriological Techniques; Biguanides; Chlorhexidine; Dental Pulp Cavity; Dentin; D

2013
Effects of different sonic activation protocols on debridement efficacy in teeth with single-rooted canals.
    Journal of dentistry, 2014, Volume: 42, Issue:8

    Topics: Biguanides; Calcium Chelating Agents; Dental Pulp Cavity; Dentin; Humans; Materials Testing; Microsc

2014
The effect of final irrigation on the penetrability of an epoxy resin-based sealer into dentinal tubules: a confocal microscopy study.
    Clinical oral investigations, 2016, Volume: 20, Issue:1

    Topics: Biguanides; Citric Acid; Doxycycline; Edetic Acid; Epoxy Resins; Humans; In Vitro Techniques; Micros

2016
Influence of diode laser application on the efficiency of QMiX and EDTA solutions in removing smear layer.
    Photomedicine and laser surgery, 2015, Volume: 33, Issue:11

    Topics: Biguanides; Edetic Acid; Humans; Lasers, Semiconductor; Microscopy, Electron, Scanning; Middle Aged;

2015
Comparison of Smear Layer Removal Ability of QMix with Different Activation Techniques.
    Journal of endodontics, 2016, Volume: 42, Issue:8

    Topics: Bicuspid; Biguanides; Dental Pulp Cavity; Humans; In Vitro Techniques; Lasers, Solid-State; Material

2016
The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris.
    Journal of endodontics, 2011, Volume: 37, Issue:1

    Topics: Biguanides; Citric Acid; Dental Pulp Cavity; Doxycycline; Drug Therapy, Combination; Edetic Acid; Hu

2011
The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris.
    Journal of endodontics, 2011, Volume: 37, Issue:6

    Topics: Biguanides; Dental Pulp Cavity; Humans; Polymers; Root Canal Irrigants; Root Canal Preparation; Smea

2011
Effectiveness of endodontic disinfecting solutions against young and old Enterococcus faecalis biofilms in dentin canals.
    Journal of endodontics, 2012, Volume: 38, Issue:10

    Topics: Anti-Infective Agents, Local; Biguanides; Biofilms; Chlorhexidine; Dentin; Dentinal Fluid; Enterococ

2012
Antibacterial and smear layer removal ability of a novel irrigant, QMiX.
    International endodontic journal, 2012, Volume: 45, Issue:4

    Topics: Anti-Infective Agents, Local; Biguanides; Biofilms; Chlorhexidine; Citric Acid; Dental Plaque; Denti

2012