Page last updated: 2024-11-08

biguanides and Pseudomonas Infections

biguanides has been researched along with Pseudomonas Infections in 18 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Pseudomonas Infections: Infections with bacteria of the genus PSEUDOMONAS.

Research Excerpts

ExcerptRelevanceReference
"The enormous tissue defects and the superinfection did not leave any hope for saving the limb from amputation."1.35[The vacuum-assisted closure (V.A.C.) and instillation dressing: limb salvage after 3 degrees open fracture with massive bone and soft tissue defect and superinfection]. ( Blanke, M; Brem, MH; Gusinde, J; Hennig, FF; Mueller, O; Olk, A; Schmidt, J, 2008)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Findlay, A1
Serrano, C1
Punzalan, S1
Fan, SL1
Phillips, PL1
Yang, Q1
Schultz, GS1
Tran, T1
Samarawickrama, C1
Petsoglou, C1
Watson, S1
Guyomarch, J1
van Nuoï, DN1
Beral, L1
Donnio, A1
Desbois, N1
Olive, C1
Theodose, R1
Merle, H1
Hübner, NO1
Matthes, R1
Koban, I1
Rändler, C1
Müller, G1
Bender, C1
Kindel, E1
Kocher, T1
Kramer, A1
Badreldin, AM1
Bader, RD1
Hekmat, K1
Werthén, M1
Davoudi, M1
Sonesson, A1
Nitsche, DP1
Mörgelin, M1
Blom, K1
Schmidtchen, A1
Motta, GJ1
Trigilia, D1
Brem, MH1
Blanke, M1
Olk, A1
Schmidt, J1
Mueller, O1
Hennig, FF1
Gusinde, J1
Michel, D1
Zäch, GA1
Wishart, MM1
Riley, TV1
Speller, DC1
Stephens, ME1
Viant, AC1
O'Flynn, JD1
Stickler, DJ1
Phillips, I1
King, A1
Jenkins, S1
Spencer, G1
Bassett, DC1
Stokes, KJ1
Thomas, WR1
Spiers, AS1
Tattersall, MH1
Gaya, H1
Muir, IF1
Owen, D1
Murphy, J1
Richards, RM1
McBride, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Kerlix AMD Gauze Study In A Burn Trauma Unit and Its Effect on Healthcare Associated Infections in Burn Patients[NCT00656708]108 participants (Actual)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for biguanides and Pseudomonas Infections

ArticleYear
Increased peritoneal dialysis exit site infections using topical antiseptic polyhexamethylene biguanide compared to mupirocin: results of a safety interim analysis of an open-label prospective randomized study.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Catheters, Indwelling; Early Termin

2013
The effect of an antimicrobial drain sponge dressing on specific bacterial isolates at tracheostomy sites.
    Ostomy/wound management, 2005, Volume: 51, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Bandages; Biguanides; Clinical Nursing Research; Disinfectants; Ente

2005
Sulfamylon acetate in the treatment of pseudomonas pyocyanea infection of burns.
    British journal of plastic surgery, 1969, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Bandages; Biguanides; Burns; Child; Clinical Trials as Topic; Female; Human

1969

Other Studies

15 other studies available for biguanides and Pseudomonas Infections

ArticleYear
The effect of negative pressure wound therapy with periodic instillation using antimicrobial solutions on Pseudomonas aeruginosa biofilm on porcine skin explants.
    International wound journal, 2013, Volume: 10 Suppl 1

    Topics: Animals; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Biofilms; Chlorhexidine; Microsco

2013
Recent cluster of childhood microbial keratitis due to orthokeratology.
    Clinical & experimental ophthalmology, 2014, Volume: 42, Issue:8

    Topics: Acanthamoeba Keratitis; Adolescent; Anti-Bacterial Agents; Biguanides; Cephalothin; Child; Chlorhexi

2014
[Infectious keratitis and cosmetic lenses: a five-case retrospective study].
    Journal francais d'ophtalmologie, 2010, Volume: 33, Issue:4

    Topics: Abscess; Acanthamoeba Keratitis; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; An

2010
Efficacy of chlorhexidine, polihexanide and tissue-tolerable plasma against Pseudomonas aeruginosa biofilms grown on polystyrene and silicone materials.
    Skin pharmacology and physiology, 2010, Volume: 23 Suppl

    Topics: Acridine Orange; Anti-Infective Agents, Local; Biguanides; Biofilms; Chlorhexidine; Gentian Violet;

2010
Successful management of a massive residual space empyema using intrathoracic vacuum-assisted instillation.
    The Thoracic and cardiovascular surgeon, 2013, Volume: 61, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Empyema, Pleural; Humans; Lun

2013
Pseudomonas aeruginosa-induced infection and degradation of human wound fluid and skin proteins ex vivo are eradicated by a synthetic cationic polymer.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:4

    Topics: Antimicrobial Cationic Peptides; Biguanides; Colony Count, Microbial; Exudates and Transudates; Huma

2004
[The vacuum-assisted closure (V.A.C.) and instillation dressing: limb salvage after 3 degrees open fracture with massive bone and soft tissue defect and superinfection].
    Der Unfallchirurg, 2008, Volume: 111, Issue:2

    Topics: Administration, Topical; Adolescent; Biguanides; Debridement; Enterobacter cloacae; Enterobacteriace

2008
Antiseptic efficacy of disinfecting solutions in suspension test in vitro against methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in pressure sore wounds after spinal cord injury.
    Dermatology (Basel, Switzerland), 1997, Volume: 195 Suppl 2

    Topics: Anti-Infective Agents, Local; Biguanides; Chamomile; Chlorhexidine; Escherichia coli; Escherichia co

1997
Infection with Pseudomonas maltophilia hospital outbreak due to contaminated disinfectant.
    The Medical journal of Australia, 1976, Nov-06, Volume: 2, Issue:19

    Topics: Adult; Aged; Australia; Biguanides; Cetrimonium Compounds; Chlorhexidine; Cross Infection; Disease O

1976
Hospital infection by Pseudomonas cepacia.
    Lancet (London, England), 1971, Apr-17, Volume: 1, Issue:7703

    Topics: Anti-Infective Agents, Local; Biguanides; Cross Infection; Disease Outbreaks; Humans; Pseudomonas; P

1971
Disinfectants and gram-negative bacteria.
    Lancet (London, England), 1972, Feb-26, Volume: 1, Issue:7748

    Topics: Biguanides; Cross Infection; Culture Media; Disinfectants; Enterobacteriaceae; Enterobacteriaceae In

1972
Control of respirator-associated infection due to Pseudomonas aeruginosa.
    Lancet (London, England), 1974, Oct-12, Volume: 2, Issue:7885

    Topics: Aerosols; Alcohols; Biguanides; Chlorobenzenes; Cross Infection; Disinfection; Evaluation Studies as

1974
Wound infection with Pseudomonas multivorans. A water-borne contaminant of disinfectant solutions.
    Lancet (London, England), 1970, Jun-06, Volume: 1, Issue:7658

    Topics: Adolescent; Adult; Aged; Biguanides; Cross Infection; Disinfectants; Drug Resistance, Microbial; Fem

1970
Indications for systemic antibiotic prophylaxis in neutropenic patients.
    British medical journal, 1974, Nov-23, Volume: 4, Issue:5942

    Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Biguanides; Blood Cell Count; Carbenicillin; Cephalot

1974
The preservation of ophthalmic solutions with antibacterial combinations.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23

    Topics: Atropine; Benzalkonium Compounds; Biguanides; Chlorobutanol; Cresols; Hot Temperature; Mercury; Opht

1971