Page last updated: 2024-11-08

biguanides and Periodontal Diseases

biguanides has been researched along with Periodontal Diseases in 20 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.

Research Excerpts

ExcerptRelevanceReference
"Periodontal diseases are common, inflammatory infections of the mouth of microbiological etiology."2.37Chemotherapy and periodontal disease--a review. ( Marder, M; Milgrom, P, 1984)
"Dental plaque is massed packed bacterial cells which accumulate on the supra- and subgingival surfaces of the teeth as well as on the oral mucosa."2.36Clinical studies of plaque control agents: an overview. ( Lobene, RR, 1979)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199020 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marder, M1
Milgrom, P1
Ciancio, SG1
Genco, RJ1
Tsao, TF1
Newman, MG1
Kwok, YY1
Horikoshi, AK1
Lobene, RR1
Gjermo, P1
Newman, PS1
Addy, M2
Joyston-Bechal, S1
Smales, FC1
Duckworth, R1
Leonard, EP1
Mandel, EJ1
Matsue, I1
Shimizu, T1
Umezawa, Y1
Kotani, A1
Shimojima, N1
Altonen, M1
SAXEN, L1
Kosunen, T1
Ainamo, J1
Bogle, G1
Rathbun, E1
Oliver, R1
Hornbuckle, C1
Egelberg, J1
Jensen, SB2
Löe, H2
Kobylańska, M1
Rudnicka, M1
Magas, A2
Wierzbicka, M2
Asboe-Jörgensen, V1
Attström, R1
Lang, NP1
Kobylaánska, M1
Iwanicka, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparing the Effect of 0,06 % -, 0,12 % and 0,2 % Chlorhexidine on Plaque, Bleeding and Side Effects in an Experimental Gingivitis Model. A Parallel, Double Masked, Randomized, Placebo-controlled Clinical Trial[NCT02911766]Phase 459 participants (Anticipated)Interventional2016-11-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for biguanides and Periodontal Diseases

ArticleYear
Chemotherapy and periodontal disease--a review.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:6

    Topics: Adult; Aging; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Biguanides

1984
Clinical studies of plaque control agents: an overview.
    Journal of dental research, 1979, Volume: 58, Issue:12

    Topics: Animals; Benzoates; Biguanides; Cetylpyridinium; Chelating Agents; Cost-Benefit Analysis; Dental Car

1979

Trials

3 trials available for biguanides and Periodontal Diseases

ArticleYear
[The double blind test on the effect of chlorhexidine-gluconate containing mouthwashes on periodontal disease (author's transl)].
    Nihon Shishubyo Gakkai kaishi, 1977, Volume: 19, Issue:4

    Topics: Aluminum; Biguanides; Chlorhexidine; Clinical Trials as Topic; Gluconates; Humans; Lactates; Mouthwa

1977
[Chlorhexedine in the etiology and therapy of parodontopathy].
    Fogorvosi szemle, 1976, Volume: 69 Suppl

    Topics: Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Denture, Partial, Removable; Gin

1976
[Evaluation of the efficacy of chlorhexidine in prevention of dental plaque].
    Czasopismo stomatologiczne, 1974, Volume: 27, Issue:4

    Topics: Biguanides; Clinical Trials as Topic; Dental Plaque; Humans; Mouthwashes; Periodontal Diseases

1974

Other Studies

15 other studies available for biguanides and Periodontal Diseases

ArticleYear
The use of antibiotics in periodontal diseases.
    The International journal of periodontics & restorative dentistry, 1983, Volume: 3, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Bacteria; B

1983
Effect of Chinese and western antimicrobial agents on selected oral bacteria.
    Journal of dental research, 1982, Volume: 61, Issue:9

    Topics: Bacteria; Biguanides; Flavonoids; Humans; Microbial Sensitivity Tests; Periodontal Diseases; Plant E

1982
Hibitane in periodontal disease.
    Journal of clinical periodontology, 1977, Volume: 4, Issue:5

    Topics: Biguanides; Chlorhexidine; Dental Plaque; Gingivitis; Humans; Periodontal Diseases; Time Factors; To

1977
A comparison of a periodontal dressing and chlorhexidine gluconate mouthwash after the internal bevelled flap procedure.
    Journal of periodontology, 1978, Volume: 49, Issue:11

    Topics: Adult; Bacteria; Biguanides; Chlorhexidine; Dental Plaque; Female; Gingival Hemorrhage; Gingival Poc

1978
The use of a chlorhexidine-containing gel in a plaque control programme.
    British dental journal, 1979, Feb-20, Volume: 146, Issue:4

    Topics: Adolescent; Adult; Aged; Biguanides; Chlorhexidine; Dental Plaque; Double-Blind Method; Female; Gels

1979
Use of chlorhexidine gluconate to prevent bone resorption in the rice rat.
    Journal of dental research, 1979, Volume: 58, Issue:2

    Topics: Administration, Topical; Alveolar Process; Animals; Biguanides; Bone Resorption; Chlorhexidine; Dent

1979
Effect of two antimicrobial rinses and oral prophylaxis on preoperative degerming of saliva.
    International journal of oral surgery, 1976, Volume: 5, Issue:6

    Topics: Adult; Aged; Bacteria; Biguanides; Cell Count; Chlorhexidine; Humans; Middle Aged; Mouthwashes; Oral

1976
Effect of post-operative use of chlorhexidine on regeneration of bifurcation defects in dogs.
    Journal of periodontal research, 1974, Volume: 9, Issue:2

    Topics: Administration, Topical; Alveolar Process; Animals; Bicuspid; Biguanides; Bone Regeneration; Dogs; F

1974
[Studies on new possibilities in plaque removable].
    Deutsche zahnarztliche Zeitschrift, 1972, Volume: 27, Issue:4

    Topics: Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dental Prophylaxis; Dextranase; Gingivitis;

1972
[Studies on new possibilities in plaque removal].
    Deutsche zahnarztliche Zeitschrift, 1972, Volume: 27, Issue:4

    Topics: Anti-Infective Agents, Local; Biguanides; Dental Plaque; Dental Prophylaxis; Dextranase; Gingivitis;

1972
Plaque control in periodontal disease.
    Journal of the American Dental Association (1939), 1973, Volume: 87, Issue:5

    Topics: Anti-Infective Agents; Biguanides; Dental Plaque; Dental Prophylaxis; Humans; Oral Hygiene; Periodon

1973
[Bacteriological and cytological studies following use of chlorhexidine].
    Czasopismo stomatologiczne, 1974, Volume: 27, Issue:7

    Topics: Anti-Infective Agents, Local; Bacteria; Biguanides; Chlorobenzenes; Drug Evaluation; Female; Humans;

1974
Effect of a chlorhexidine dressing on the healing after periodontal surgery.
    Journal of periodontology, 1974, Volume: 45, Issue:1

    Topics: Adult; Biguanides; Evaluation Studies as Topic; Female; Gingival Crevicular Fluid; Humans; Male; Met

1974
[Hibitane is used?].
    Tidning. Sveriges Tandlakarforbund, 1970, Jul-15, Volume: 62, Issue:14

    Topics: Anti-Infective Agents, Local; Biguanides; Dentistry; Periodontal Diseases

1970
[Chlorhexidine? A talk with professor Löe in Arhus].
    Tidens tann, 1970, Volume: 31, Issue:4

    Topics: Biguanides; Dentistry; Periodontal Diseases

1970