biguanides has been researched along with Pancreatic Neoplasms in 7 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Alexidine Dihydrochloride (AD), an orally bioavailable bis-biguanide compound, is an apoptosis stimulating reagent." | 1.56 | Repurposing of Alexidine Dihydrochloride as an Apoptosis Initiator and Cell Cycle Inhibitor in Human Pancreatic Cancer. ( Aydemir, E; Bayrak, OF; Kasikci, E; Sahin, F; Yogurtcu, BM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 1 |
| Mushashi, F | 1 |
| Son, S | 1 |
| Bhatti, P | 1 |
| Dummer, T | 1 |
| Murphy, RA | 1 |
| Kasikci, E | 1 |
| Aydemir, E | 1 |
| Yogurtcu, BM | 1 |
| Sahin, F | 1 |
| Bayrak, OF | 1 |
| Hébert, A | 1 |
| Parisotto, M | 1 |
| Rowell, MC | 1 |
| Doré, A | 1 |
| Fernandez Ruiz, A | 1 |
| Lefrançois, G | 1 |
| Kalegari, P | 1 |
| Ferbeyre, G | 1 |
| Schmitzer, AR | 1 |
| Maddocks, ODK | 1 |
| Athineos, D | 1 |
| Cheung, EC | 1 |
| Lee, P | 1 |
| Zhang, T | 1 |
| van den Broek, NJF | 1 |
| Mackay, GM | 1 |
| Labuschagne, CF | 1 |
| Gay, D | 1 |
| Kruiswijk, F | 1 |
| Blagih, J | 1 |
| Vincent, DF | 1 |
| Campbell, KJ | 1 |
| Ceteci, F | 1 |
| Sansom, OJ | 1 |
| Blyth, K | 1 |
| Vousden, KH | 1 |
| Herrera-Martínez, AD | 1 |
| Pedraza-Arevalo, S | 1 |
| L-López, F | 1 |
| Gahete, MD | 1 |
| Gálvez-Moreno, MA | 1 |
| Castaño, JP | 1 |
| Luque, RM | 1 |
| Chiu, CC | 1 |
| Huang, CC | 1 |
| Chen, YC | 1 |
| Chen, TJ | 1 |
| Liang, Y | 1 |
| Lin, SJ | 1 |
| Chen, JW | 1 |
| Leu, HB | 1 |
| Chan, WL | 1 |
| Luk'ianchikov, VS | 1 |
1 review available for biguanides and Pancreatic Neoplasms
| Article | Year |
|---|---|
Diabetes medications and cancer risk associations: a systematic review and meta-analysis of evidence over the past 10 years.
Topics: Biguanides; Colorectal Neoplasms; Diabetes Mellitus; Humans; Insulin; Insulin Secretagogues; Male; P | 2023 |
6 other studies available for biguanides and Pancreatic Neoplasms
| Article | Year |
|---|---|
Repurposing of Alexidine Dihydrochloride as an Apoptosis Initiator and Cell Cycle Inhibitor in Human Pancreatic Cancer.
Topics: Antineoplastic Agents; Apoptosis; Biguanides; Cell Cycle; Cell Line; Dose-Response Relationship, Dru | 2020 |
Phenylethynylbenzyl-modified biguanides inhibit pancreatic cancer tumor growth.
Topics: AMP-Activated Protein Kinases; Animals; Biguanides; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; | 2021 |
Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Topics: Animals; Antioxidants; Biguanides; Cell Line, Tumor; Diet; Disease Models, Animal; Female; Food Depr | 2017 |
Type 2 Diabetes in Neuroendocrine Tumors: Are Biguanides and Statins Part of the Solution?
Topics: Adult; Aged; Apoptosis; Biguanides; Carcinoid Tumor; Cell Line, Tumor; Cell Movement; Cell Prolifera | 2019 |
Increased risk of gastrointestinal malignancy in patients with diabetes mellitus and correlations with anti-diabetes drugs: a nationwide population-based study in Taiwan.
Topics: alpha-Glucosidases; Biguanides; Cohort Studies; Diabetes Mellitus; Digestive System Neoplasms; Human | 2013 |
[Diagnosis and treatment of hypoglycemia syndrome].
Topics: Biguanides; Blood Glucose; Diagnosis, Differential; Diet; Glucose Tolerance Test; Humans; Hypoglycem | 1982 |