biguanides has been researched along with Osteoarthritis, Knee in 2 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our hypothesis was that antiseptics and supplemental irrigation with sodium chloride lavage are less toxic on human chondrocytes than treatment with antiseptics only." | 1.37 | Toxicity of antiseptics against chondrocytes: what is best for the cartilage in septic joint surgery? ( Arnholdt, J; Kolar, P; Matziolis, G; Perka, C; Röhner, E; Seeger, JB; Thiele, K, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Röhner, E | 2 |
| Hoff, P | 1 |
| Gaber, T | 1 |
| Lang, A | 1 |
| Vörös, P | 1 |
| Buttgereit, F | 1 |
| Perka, C | 2 |
| Windisch, C | 1 |
| Matziolis, G | 2 |
| Kolar, P | 1 |
| Seeger, JB | 1 |
| Arnholdt, J | 1 |
| Thiele, K | 1 |
2 other studies available for biguanides and Osteoarthritis, Knee
| Article | Year |
|---|---|
Cytokine expression in human osteoblasts after antiseptic treatment: a comparative study between polyhexanide and chlorhexidine.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Bone Marrow; Cell Adhesion; Cell Shape; Cells, Cult | 2015 |
Toxicity of antiseptics against chondrocytes: what is best for the cartilage in septic joint surgery?
Topics: Anti-Infective Agents, Local; Arthritis, Infectious; Biguanides; Cartilage, Articular; Cell Count; C | 2011 |