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biguanides and Obesity

biguanides has been researched along with Obesity in 99 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"The present study represents a new insight into the Biguanides and the Prevention of the Risk of Obesity (BIGPRO) 1 study population at inclusion."7.71Accumulation of triglyceride-rich lipoprotein in subjects with abdominal obesity: the biguanides and the prevention of the risk of obesity (BIGPRO) 1 study. ( André, P; Bard, JM; Charles, MA; Eschwege, E; Fruchart, JC; Juhan-Vague, I; Safar, M; Vague, P, 2001)
"The therapeutic effect of short-term buformin (l-butylbiguanide) treatment was investigated in 12 patients with reactive hypoglycemia."7.65Treatment of reactive hypoglycemia with buformin. ( Cabrijan, T; Sekso, M; Solter, M; Zjacić, V, 1975)
" A multivariate analysis with multiple logistic regression revealed that visceral fat accumulation was inhibited in women and those taking statins or thiazolidines and aggravated in men and those with obesity or an increased waist circumference."3.80Estimation of visceral fat and fatty liver disease using ultrasound in patients with diabetes. ( Ichikawa, T; Kohno, S; Nakao, K; Onitsuka, Y; Takeshima, F, 2014)
"Our results conclude that 10% decrease in body mass index (BMI) among overweight patients, smoking cessation, initiation to undertake a preventive treatment with low-dose aspirin, initiation to undertake or intensify blood pressure control, initiation to undertake or intensify lipidic control, and shift to biguanides among overweight patients are factors associated with significant benefits (avoided costs) which compensate for the increase in treatment costs."3.73[Assessment of the budgetary impact of treatment guidelines in type II diabetes mellitus in France]. ( Crainich, D; Lebrun, T; Marissal, JP; Sailly, JC, 2005)
"The present study represents a new insight into the Biguanides and the Prevention of the Risk of Obesity (BIGPRO) 1 study population at inclusion."3.71Accumulation of triglyceride-rich lipoprotein in subjects with abdominal obesity: the biguanides and the prevention of the risk of obesity (BIGPRO) 1 study. ( André, P; Bard, JM; Charles, MA; Eschwege, E; Fruchart, JC; Juhan-Vague, I; Safar, M; Vague, P, 2001)
" In Austria, the association of lactic acidosis with biguanide therapy has led to a cancellation of the registration of buformin and phenformin."3.66[Biguanides: reasons for withdrawal of drugs and remaining indications]. ( Bolzano, K, 1978)
"The therapeutic effect of short-term buformin (l-butylbiguanide) treatment was investigated in 12 patients with reactive hypoglycemia."3.65Treatment of reactive hypoglycemia with buformin. ( Cabrijan, T; Sekso, M; Solter, M; Zjacić, V, 1975)
"The management of type 1 diabetes remains a challenge for clinicians."2.52The treatment of type 1 diabetes mellitus with agents approved for type 2 diabetes mellitus. ( Davis, SN; Munir, KM, 2015)
"The majority of patients with type 2 diabetes mellitus are overweight or obese at the time of diagnosis, and obesity is a recognised risk factor for type 2 diabetes and coronary heart disease (CHD)."2.44Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus. ( Hermansen, K; Mortensen, LS, 2007)
" Despite historic reliance on these agents to treat type 2 diabetes, long-term use of SUs may desensitize beta cells."2.40Effects of current therapeutic interventions on insulin resistance. ( Kobayashi, M, 1999)
"we studied a group of 268 patients with type 2 diabetes, aged between 30 and 50 years, with a diabetes duration of less than 5 years."1.32The value of basal C peptide and its relationship with pancreatic autoantibodies in young adults with type 2 diabetes mellitus. ( Roşu, M; Serban, V; Sima, A; Timar, R; Vlad, A, 2004)
"Obesity is a social disease and amounts to a real medical problem."1.29[Obesity: a multifactorial disorder with difficult long-term treatment]. ( Cotrozzi, G; Fontana, R; Relli, P, 1994)
"The biguanides were a therapeutic enrichment particularly in the treatment of adipose elderly diabetics with obligatory diet."1.26[Indications and results of an additional differentiated pharmacotherapy of obesity]. ( Kucher, E, 1978)

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199080 (80.81)18.7374
1990's5 (5.05)18.2507
2000's10 (10.10)29.6817
2010's4 (4.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babenko, AY1
Savitskaya, DA1
Kononova, YA1
Trofimova, AY1
Simanenkova, AV1
Vasilyeva, EY1
Shlyakhto, EV1
Onitsuka, Y1
Takeshima, F1
Ichikawa, T1
Kohno, S1
Nakao, K1
Munir, KM1
Davis, SN1
Huber, DA1
Schreihofer, AM1
TEITELBAUM, M1
LEMARCHANT, JM1
BERNHARD, H1
Vlad, A1
Serban, V1
Sima, A1
Timar, R1
Roşu, M1
Purnell, JQ1
Weyer, C1
Marissal, JP1
Sailly, JC1
Crainich, D1
Lebrun, T1
Batsis, JA1
Nieto-Martinez, RE1
Lopez-Jimenez, F1
Hermansen, K1
Mortensen, LS1
Rabasseda, X1
Melero Paredes, S1
Antolínez de Abia, N1
Durán García, S1
Hernández Herrero, C1
Schernthaner, G1
Prager, R1
Cotrozzi, G1
Relli, P1
Fontana, R1
Golay, A1
Lehmann, T1
Ferrari De Fusco, B1
Skyler, JS1
Kasuga, M1
Hunabiki, A1
Morita, S1
Kobayashi, M1
Ageeva, VV1
Krasil'nikova, EI1
Zubina, IM1
Shliakhto, EV1
Bard, JM1
Charles, MA1
Juhan-Vague, I1
Vague, P1
André, P1
Safar, M1
Fruchart, JC1
Eschwege, E1
Drake, AJ1
Smith, A1
Betts, PR1
Crowne, EC1
Shield, JP1
Walter-Sack, I1
Bloom, A2
Estivals, JP1
Giraudet, MC1
Videau, JY1
Giulietti, M1
Vasiukova, EA3
Granovskaia-Tsvetkova, AM2
Olefirenko, VT1
Vinogradova, IM1
Lefebvre, P1
Luyckx, A1
Mosora, F1
Lacroix, M1
Pirnay, F1
Kucher, E1
Bolzano, K1
Sauer, H1
Schneider, B1
Schräpler, P2
Schulz, E2
Nijssen, J1
Adlung, J2
Granovskaia-Tsetkova, AM1
Pisarskaia, IV1
Spanár, E1
Uhrín, P1
Levcík, A1
Záhradný, V1
Faludi, G1
Adolph, W1
Panzram, G2
Ruttmann, B1
Berchtold, P2
Berger, M1
Gries, FA2
Liashko, KIa1
Severova, TM1
Peregudov, AIa1
Sergeev, OI1
Sekso, M1
Solter, M1
Zjacić, V1
Cabrijan, T1
Riviere, J1
Manchiet, G1
Opitz, K1
Neumann, VI1
Michaelis, D2
Schulz, B1
Wulfert, P1
Heinke, P1
Mirouze, J1
Cartry, E1
Héraïef, E1
Burckhardt, P1
Füessl, HS1
Blatniczky, L1
Kautzky, L1
Péter, F1
Pan'kiv, VI1
Stowers, JM2
Kryston, LJ1
Shaw, RA1
Mashaly, M1
el-Ebrashy, N1
Higazi, AM1
Einen, MA1
Aziz, MT1
Leupold, H1
Schrub, JC1
Hillemand, B1
Dubuisson, M1
Tatoń, J1
Fedyna, M1
Tikholov, K1
Strata, A2
Zuliani, U2
Cucurachi, L2
Dell'anna, A2
Pelti, M1
Del Guercio, MJ1
Caccamo, A1
Garlaschi, C1
Di Natale, B1
Episcopi, ME1
Moreno, A1
Hockaday, TD1
Plauchu, M1
Nove-Josserand, G1
Philippe, LP1
Hallacq, A1
Valancogne, C1
Dumont, JP1
Mincu, I3
Dumitrescu, C2
Mihalache, N3
Leng-Lévy, J2
Leng, B2
Aubertin, J2
Lacut, JY1
Le Gall, F1
Boget, JC1
Lenoir, MP1
Câmpeanu, S1
Georgescu-Iancu, M1
Bäbler, M1
Wechsler, B1
Kopp, H2
Cucurachi, P1
Levine, R1
Liebermeister, H1
Pogátsa, G2
Arky, RA1
Abramson, EA1
Bewsher, PD1
Butterfield, WJ1
Felber, JP1
Keiser, G1
Bolli, P1
Arbenz, U1
Ricketts, HT1
Irsigler, K1
Bretán, M1
Balázsi, I1
Marion, J1
Nogué, F1
Curchod, B1
Raptis, S1
Rothenbuchner, G1
Pfeiffer, EF1
Bruns, W1
Wappler, E1
Möller, E1
Pedersen, J1
Brugi, A1
Gironi, G1
Ferrari, ML1
Gérard, A1
Bittnerová, H1
Masek, J1
Rath, R1

Reviews

16 reviews available for biguanides and Obesity

ArticleYear
The treatment of type 1 diabetes mellitus with agents approved for type 2 diabetes mellitus.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:15

    Topics: Biguanides; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors

2015
Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity.
    Treatments in endocrinology, 2003, Volume: 2, Issue:1

    Topics: Amyloid; Benzamides; Biguanides; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes

2003
Metabolic syndrome: from global epidemiology to individualized medicine.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Anti-Obesity Agents; Bariatric Surgery; Biguanides; Body Mass Index; Caloric Restriction; Cardiovasc

2007
Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus.
    Drug safety, 2007, Volume: 30, Issue:12

    Topics: Amyloid; Benzamides; Biguanides; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inh

2007
[Physiologic and physiopathologic implications of insulin-receptor interaction (II). Pathologic situations in which changes in insulin-receptor interaction are detected].
    Medicina clinica, 1984, Apr-14, Volume: 82, Issue:14

    Topics: Acanthosis Nigricans; Animals; Biguanides; Child; Diabetes Complications; Diabetes Mellitus, Type 1;

1984
[Insulin receptor and postreceptor disorders: significance for the development and therapy of carbohydrate metabolic disorders].
    Acta medica Austriaca, 1984, Volume: 11, Issue:3-4

    Topics: Autoantibodies; Biguanides; Body Weight; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus;

1984
[Etiology and therapy of insulin resistance].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9

    Topics: Animals; Arteriosclerosis; Biguanides; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertens

1999
Effects of current therapeutic interventions on insulin resistance.
    Diabetes, obesity & metabolism, 1999, Volume: 1 Suppl 1

    Topics: Biguanides; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet; Enzyme Inhibitors; Exercise; Glycosi

1999
[Reduction and delay in resorption as a pathogenetic and therapeutic principle].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1979, Volume: 16

    Topics: Biguanides; Bile Acids and Salts; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Protei

1979
Some practical aspects of the management of diabetes.
    Clinics in endocrinology and metabolism, 1977, Volume: 6, Issue:2

    Topics: Adult; Biguanides; Body Weight; Child; Contraceptives, Oral; Diabetes Complications; Diabetes Mellit

1977
[What is achieved by the therapy with oral antidiabetics?].
    Der Internist, 1976, Volume: 17, Issue:12

    Topics: Administration, Oral; Adult; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; D

1976
[Drug treatment of obesity].
    Therapeutische Umschau. Revue therapeutique, 1989, Volume: 46, Issue:5

    Topics: Antidepressive Agents; Appetite Depressants; Biguanides; Diuretics; Humans; Obesity; Thyroid Hormone

1989
Oral treatment in diabetes.
    Clinics in endocrinology and metabolism, 1972, Volume: 1, Issue:3

    Topics: Acetohexamide; Acidosis; Administration, Oral; Animals; Biguanides; Cardiovascular Diseases; Chlorpr

1972
Diabetes mellitus.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Alcohol Drinking; Anxiety; Biguanides; Blood Glucose; Blood Pressure; Body Weight; Cholesterol, Diet

1974
Obesity and diabetes; a review.
    Postgraduate medical journal, 1971, Volume: 47

    Topics: Adipose Tissue; Animals; Biguanides; Diabetes Mellitus; Diet, Reducing; Female; Glucose Tolerance Te

1971
New horizons in our knowledge of diabetes mellitus.
    Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:11

    Topics: Animals; Biguanides; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Glucagon; Glu

1971

Trials

8 trials available for biguanides and Obesity

ArticleYear
[Fliformine effects on blood lipid spectrum and lipid peroxidation in obese patients].
    Klinicheskaia meditsina, 2000, Volume: 78, Issue:10

    Topics: Biguanides; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Lipid Peroxidat

2000
[Survey of 832 case records of diabetes of adult onset treated by Diamicron. Evolution of metabolism and weight].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1978

    Topics: Adult; Aged; Biguanides; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes Mellitus; Fe

1978
[Prospective studies on the prevention of manifestations of protodiabetes using sulfonylurea compounds and biguanides].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1976, Jan-01, Volume: 31, Issue:1

    Topics: Biguanides; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Obesity; Prediabetic State; Sulfon

1976
Clinical experiences on therapeutic measures of obesity.
    Giornale di clinica medica, 1974, Volume: 55, Issue:10

    Topics: Appetite Depressants; Biguanides; Diabetes Mellitus; Diet, Reducing; Fasting; Humans; Obesity; Place

1974
[Biguanides in treatment of obesity. II. Controlled clinical research with placebos, metformin and phenformin in obesity with normal and reduced tolerance to carbohydrates].
    La Clinica terapeutica, 1968, Nov-15, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Aged; Biguanides; Carbohydrate Metabolism; Clinical Trials as Topic; Diabetes Mel

1968
Insulin response to glucose in the presence of oral hypoglycemics.
    Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3

    Topics: Adolescent; Adult; Biguanides; Chlorpropamide; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucos

1968
[Effect of metformin on glucose utilization and body weight].
    Deutsche medizinische Wochenschrift (1946), 1970, Oct-23, Volume: 95, Issue:43

    Topics: Biguanides; Blood Glucose; Body Weight; Glucose; Glucose Tolerance Test; Humans; Injections, Intrave

1970
[The importance of the biguanides in the treatment of obesity].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Mar-01, Volume: 24, Issue:5

    Topics: Adult; Appetite Depressants; Biguanides; Blood Glucose; Body Weight; Cholesterol; Diet, Reducing; Fa

1969

Other Studies

75 other studies available for biguanides and Obesity

ArticleYear
Predictors of Effectiveness of Glucagon-Like Peptide-1 Receptor Agonist Therapy in Patients with Type 2 Diabetes and Obesity.
    Journal of diabetes research, 2019, Volume: 2019

    Topics: Adult; Aged; Atherosclerosis; Biguanides; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes M

2019
Estimation of visceral fat and fatty liver disease using ultrasound in patients with diabetes.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:6

    Topics: Aged; Biguanides; Body Composition; Body Mass Index; Diabetes Mellitus, Type 2; Diet, Western; Femal

2014
Attenuated baroreflex control of sympathetic nerve activity in obese Zucker rats by central mechanisms.
    The Journal of physiology, 2010, May-01, Volume: 588, Issue:Pt 9

    Topics: Animals; Baroreflex; Biguanides; Blood Pressure; Central Nervous System; Data Interpretation, Statis

2010
[BIGUANIDES AND SULFONAMIDES IN SMALL DOSES IN THE INITIAL TREATMENT OF THE DIABETES OF THE OBESE PERSON].
    Le Diabete, 1963, Volume: 11

    Topics: Biguanides; Chlorpropamide; Diabetes Mellitus; Humans; Metformin; Obesity; Sulfanilamide; Sulfanilam

1963
LONG-TERM OBSERVATIONS ON ORAL HYPOGLYCEMIC AGENTS IN DIABETES; THE EFFECT OF CARBUTAMIDE AND TOLBUTAMIDE.
    Diabetes, 1965, Volume: 14

    Topics: Biguanides; Biomedical Research; Carbutamide; Diabetes Mellitus; Diet; Diet Therapy; Diseases in Twi

1965
The value of basal C peptide and its relationship with pancreatic autoantibodies in young adults with type 2 diabetes mellitus.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2004, Volume: 42, Issue:2

    Topics: Adult; Autoantibodies; Biguanides; Biomarkers; Body Mass Index; Body Weight; C-Peptide; Diabetes Mel

2004
[Assessment of the budgetary impact of treatment guidelines in type II diabetes mellitus in France].
    Revue d'epidemiologie et de sante publique, 2005, Volume: 53 Spec No 1

    Topics: Adolescent; Adult; Aged; Aspirin; Biguanides; Cerebrovascular Disorders; Coronary Disease; Cost-Bene

2005
From insulin to incretins: a report from the 67th scientific sessions of the American Diabetes Association.
    Timely topics in medicine. Cardiovascular diseases, 2007, Aug-01, Volume: 11

    Topics: Biguanides; Diabetes Complications; Diabetes Mellitus; Diet; Dietary Supplements; Dipeptidyl-Peptida

2007
[Oral anti-diabetes medicines, an update].
    Revista de enfermeria (Barcelona, Spain), 2008, Volume: 31, Issue:3

    Topics: Administration, Oral; Biguanides; Body Mass Index; Contraindications; Diabetes Mellitus; Humans; Hyp

2008
[Obesity: a multifactorial disorder with difficult long-term treatment].
    La Clinica terapeutica, 1994, Volume: 145, Issue:11

    Topics: Adolescent; Adult; Albuterol; Appetite Depressants; Biguanides; Cimetidine; Diet, Reducing; Female;

1994
[How should an obese diabetic patient be treated?].
    Revue medicale de la Suisse romande, 1993, Volume: 113, Issue:9

    Topics: Biguanides; Diabetes Mellitus; Diet, Reducing; Dietary Carbohydrates; Dietary Fats; Humans; Obesity;

1993
Targeted glycemic control in type 2 diabetes.
    The Journal of the Florida Medical Association, 1998, Volume: 85, Issue:2

    Topics: Aged; Algorithms; Anti-Obesity Agents; Biguanides; Blood Glucose; Blood Glucose Self-Monitoring; Chr

1998
Accumulation of triglyceride-rich lipoprotein in subjects with abdominal obesity: the biguanides and the prevention of the risk of obesity (BIGPRO) 1 study.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:3

    Topics: Abdomen; Adult; Aged; Biguanides; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Female

2001
Type 2 diabetes in obese white children.
    Archives of disease in childhood, 2002, Volume: 86, Issue:3

    Topics: Adolescent; Biguanides; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female

2002
[Biguanides in the treatment of obesity].
    La Clinica terapeutica, 1978, Jan-15, Volume: 84, Issue:1

    Topics: Biguanides; Diabetes Mellitus; Drug Therapy, Combination; Glyburide; Humans; Insulin; Obesity; Phenf

1978
[Obesity and diabetes mellitus].
    Klinicheskaia meditsina, 1979, Volume: 57, Issue:1

    Topics: Biguanides; Diabetes Mellitus; Diuretics; Female; Humans; Male; Mazindol; Obesity

1979
[Dynamics of lipid and carbohydrate metabolism in various methods of treatment of obesity].
    Terapevticheskii arkhiv, 1979, Volume: 51, Issue:12

    Topics: Adult; Baths; Biguanides; Diet, Reducing; Female; Glucose; Humans; Lipid Metabolism; Male; Middle Ag

1979
Oxidation of an exogenous glucose load using naturally labelled 13C-glucose. Effect of butylbiguanide therapy in obese mildly diabetic subjects.
    Diabetologia, 1978, Jan-14, Volume: 14, Issue:1

    Topics: Adult; Biguanides; Blood Glucose; Buformin; Carbon Dioxide; Carbon Isotopes; Diabetes Mellitus; Fatt

1978
[Indications and results of an additional differentiated pharmacotherapy of obesity].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1978, Oct-15, Volume: 33, Issue:20

    Topics: Adolescent; Adult; Aged; Biguanides; Diabetes Mellitus; Diet, Reducing; Female; Furosemide; Humans;

1978
[Biguanides: reasons for withdrawal of drugs and remaining indications].
    Acta medica Austriaca, 1978, Volume: 5, Issue:3

    Topics: Acidosis; Austria; Biguanides; Buformin; Diabetes Mellitus; Humans; Lactates; Legislation, Drug; Met

1978
[Effect of butylbiguanide in retard form on the glucose resorption and lactate-pyruvate concentration in blood].
    Die Medizinische Welt, 1977, Mar-04, Volume: 28, Issue:9

    Topics: Adult; Aged; Biguanides; Buformin; Delayed-Action Preparations; Glucose; Humans; Lactates; Middle Ag

1977
[Obesity (clinical picture and treatment)].
    Klinicheskaia meditsina, 1977, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Appetite Depressants; Biguanides; Humans; Obesity

1977
[Effect of some hormones and drug preparations on hemocoagulation in endocrine diseases].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Aged; Biguanides; Blood Coagulation; Cushing Syndrome; Diabetes Mellitus; Female;

1977
[Pathogenetic relationships between obesity and maturity-onset diabetes].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jun-01, Volume: 32, Issue:11

    Topics: Adult; Biguanides; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin;

1977
Controlling diabetes with diet and oral hypoglycemic agents.
    Geriatrics, 1976, Volume: 31, Issue:10

    Topics: Administration, Oral; Biguanides; Diabetes Mellitus; Diet, Diabetic; Drug Administration Schedule; H

1976
[Overweight and diabetes (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1976, Volume: 33, Issue:11

    Topics: Biguanides; Diabetes Mellitus; Diet, Reducing; Humans; Obesity; Sulfonylurea Compounds

1976
[Modern therapy of diabetes mellitus in obese patients].
    Sovetskaia meditsina, 1975, Issue:6

    Topics: Adult; Aged; Appetite Depressants; Biguanides; Diabetes Mellitus; Humans; Hypoglycemic Agents; Middl

1975
[Effect of Buformin retard in adipose patients with impaired glucose tolerance].
    Die Medizinische Welt, 1975, Oct-17, Volume: 26, Issue:42

    Topics: Adult; Aged; Biguanides; Blood Glucose; Buformin; Fatty Acids, Nonesterified; Glucose; Glycerol; Hum

1975
Treatment of reactive hypoglycemia with buformin.
    The American journal of clinical nutrition, 1975, Volume: 28, Issue:11

    Topics: Adult; Biguanides; Blood Glucose; Buformin; Female; Glucose Tolerance Test; Humans; Hypoglycemia; In

1975
[Biguanides and obesity].
    Semaine des hopitaux. Therapeutique, 1975, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Aged; Biguanides; Female; Humans; Middle Aged; Obesity

1975
[Pharmacotherapeutic possibilities in obesity].
    Medizinische Monatsschrift, 1975, Volume: 29, Issue:12

    Topics: Appetite Depressants; Biguanides; Carrageenan; Chorionic Gonadotropin; Fenfluramine; Glucose; Growth

1975
[Results of long-term biguanide therapy as a preventive measure in protodiabetes].
    Endokrinologie, 1975, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Biguanides; Blood Glucose; Diabetes Mellitus; Female; Humans; Insulin; Male; Midd

1975
[Diabetes mellitus under 30 years of age. Results of 18 years experience with oral treatment (author's transl)].
    Diabete & metabolisme, 1975, Volume: 1, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Biguanides; Child; Child, Preschool; Diabetes Complications

1975
Delaying carbohydrate absorption in noninsulin-dependent diabetes mellitus: useful therapy?
    Klinische Wochenschrift, 1987, May-04, Volume: 65, Issue:9

    Topics: Acarbose; Biguanides; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus; Diabetes Mellitus

1987
[The effect of adebit on carbohydrate and insulin metabolism in childhood obesity].
    Orvosi hetilap, 1986, Jun-08, Volume: 127, Issue:23

    Topics: Adolescent; Age Factors; Biguanides; Buformin; C-Peptide; Child; Child, Preschool; Humans; Infant; I

1986
[Differential treatment of patients with newly detected diabetes mellitus].
    Vrachebnoe delo, 1985, Issue:10

    Topics: Adolescent; Adult; Aged; Biguanides; Combined Modality Therapy; Diabetes Mellitus; Diet Therapy; Hum

1985
[Biguanide therapy of obesity?].
    Deutsche medizinische Wochenschrift (1946), 1973, Sep-28, Volume: 98, Issue:39

    Topics: Biguanides; Humans; Long-Term Care; Obesity

1973
The rationale for the use of drugs in the treatment of diabetes mellitus.
    Seminars in drug treatment, 1974,Spring, Volume: 3, Issue:4

    Topics: Administration, Oral; Biguanides; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabe

1974
Oral management of uncomplicated maturity onset diabetes.
    The Journal of the Egyptian Medical Association, 1974, Volume: 57, Issue:7-8

    Topics: Adult; Aged; Biguanides; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Glucose Toleran

1974
[Studies on the course of mass screening in discovered diabetic patients].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Jul-01, Volume: 29, Issue:13

    Topics: Adolescent; Adult; Aged; Biguanides; Child; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; Hu

1974
Joly JP: [Obesity and fast therapy. Immediate and long-term reducing].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1971, Jan-20, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Appetite Depressants; Biguanides; Diet, Reducing; Diuretics; Fasting; Female; Hum

1971
[Pathophysiological principles of dose selecting and pharmacodynamic properties of insulin preparations for treatment of diabetes].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1971, Jan-11, Volume: 26, Issue:2

    Topics: Adrenocorticotropic Hormone; Biguanides; Circadian Rhythm; Diabetes Mellitus; Diet; Dietary Carbohyd

1971
[Treatment of patients with diabetes and diabetic angiopathies of the lower extremities with butylbiguanide (Silubin retard)].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Biguanides; Diabetes Mellitus; Diabetic Angiopathies

1974
[Possibilities and limits of primary prevention in diabetes mellitus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Sep-15, Volume: 29, Issue:18

    Topics: Biguanides; Body Weight; Diabetes Mellitus; Diabetic Angiopathies; Dietary Carbohydrates; Female; Hu

1974
[Effects of dimethylbiguanide on glucose tolerance and on betapancreatic function in obese children with normal glucose tolerance].
    Minerva pediatrica, 1974, Sep-08, Volume: 26, Issue:27

    Topics: Biguanides; Blood Glucose; Carbohydrate Metabolism; Child; Diabetes Mellitus, Type 1; Female; Glucos

1974
[Senile diabetes].
    Lyon medical, 1972, Sep-10, Volume: 228, Issue:13

    Topics: Age Factors; Aged; Biguanides; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Diet Therap

1972
[Changes of fibrinolytic activity in obese diabetics during treatment with delayed-action Silubin].
    Medicina interna, 1972, Volume: 24, Issue:12

    Topics: Adult; Biguanides; Delayed-Action Preparations; Diabetes Mellitus; Female; Fibrinolysis; Humans; Mal

1972
[The biguanides-insulin combination in the treatment of certain types of diabetes].
    Bordeaux medical, 1972, Volume: 5, Issue:19

    Topics: Adolescent; Adult; Aged; Biguanides; Child; Diabetes Mellitus; Evaluation Studies as Topic; Female;

1972
Changes of fibrinolytic activity in obese diabetics after treatment with Silubin retard.
    Revue roumaine de medecine interne (1964), 1973, Volume: 10, Issue:1

    Topics: Biguanides; Cholesterol; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Fibrinolysis; Humans

1973
N 1 -n-butyl-biguanide influence on peripheral assimilation of glucose.
    Revue roumaine de medecine interne (1964), 1973, Volume: 10, Issue:2

    Topics: Adult; Biguanides; Blood Glucose; Butanes; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Hum

1973
[Diabetes mellitus and obesity: monotherapy using biguanides].
    Schweizerische medizinische Wochenschrift, 1973, Apr-28, Volume: 103, Issue:17

    Topics: Adult; Biguanides; Body Weight; Child; Diabetes Mellitus; Diarrhea; Diet Therapy; Flatulence; Humans

1973
[Management of diabetes mellitus].
    La Nouvelle presse medicale, 1974, Mar-02, Volume: 3, Issue:9

    Topics: Adult; Aged; Biguanides; Body Weight; Diabetes Mellitus; Diet Therapy; Humans; Hyperglycemia; Insuli

1974
[Clinical tests on Glucophage retard in 50 obese adult patients with adjusted diabetes mellitus].
    Die Medizinische Welt, 1974, Apr-12, Volume: 25, Issue:15

    Topics: Aged; Biguanides; Delayed-Action Preparations; Diabetes Mellitus; Female; Humans; Male; Middle Aged;

1974
[Therapy of obesity].
    Deutsche medizinische Wochenschrift (1946), 1972, Feb-04, Volume: 97, Issue:5

    Topics: Appetite Depressants; Biguanides; Diet Therapy; Diet, Reducing; Humans; Obesity

1972
Diabetes mellitus--refractory obesity.
    British medical journal, 1972, Jul-15, Volume: 3, Issue:5819

    Topics: Biguanides; Diabetes Mellitus; Diet Therapy; Female; Fetal Death; Glucose Tolerance Test; Glycosuria

1972
New data on Adebit treatment of diabetes.
    Therapia Hungarica (English edition), 1971, Volume: 19, Issue:2

    Topics: Biguanides; Body Weight; Butanes; Diabetes Mellitus; Drug Therapy, Combination; Humans; Hypoglycemic

1971
Studies on the mechanism of weight reduction by phenformin.
    Postgraduate medical journal, 1969, Volume: 45

    Topics: Biguanides; Diabetes Mellitus; Female; Humans; Metformin; Obesity; Phenformin

1969
Effects of biguanides on peripheral tissues.
    Acta diabetologica latina, 1969, Volume: 6 Suppl 1

    Topics: Basement Membrane; Biguanides; Blood Glucose; Forearm; Glucose; Glucose Tolerance Test; Glycolysis;

1969
[Mode of action of oral hypoglycemic agents].
    Revue medicale de la Suisse romande, 1969, Volume: 89, Issue:9

    Topics: Administration, Oral; Biguanides; Diabetes Complications; Humans; Hypoglycemic Agents; Obesity; Panc

1969
The management of obesity.
    Drug and therapeutics bulletin, 1969, Nov-21, Volume: 7, Issue:24

    Topics: Adolescent; Adult; Amphetamine; Biguanides; Child, Preschool; Diet Therapy; Fasting; Humans; Infant;

1969
[Disorder of the vitamin B 12 absorption after biguanid therapy].
    Schweizerische medizinische Wochenschrift, 1970, Feb-14, Volume: 100, Issue:7

    Topics: Biguanides; Cobalt Isotopes; Diabetes Mellitus; Diarrhea; Humans; Intestinal Absorption; Intrinsic F

1970
[Current data on the treatment of diabetics with Adebit].
    Orvosi hetilap, 1970, Apr-12, Volume: 111, Issue:15

    Topics: Ambulatory Care; Biguanides; Diabetes Mellitus; Drug Synergism; Humans; Hypoglycemic Agents; Obesity

1970
Weight change with orally administered "antidiabetic" drugs.
    JAMA, 1970, Sep-07, Volume: 213, Issue:10

    Topics: Adipose Tissue; Administration, Oral; Animals; Biguanides; Body Weight; Diabetes Mellitus; Diet; Fem

1970
Experiences with Adebit in the treatment of the maturity onset diabetes.
    Therapia Hungarica (English edition), 1970, Volume: 18, Issue:2

    Topics: Administration, Oral; Age Factors; Aged; Biguanides; Diabetes Mellitus; Female; Humans; Hypoglycemic

1970
[Glidiazine in the treatment of diabetes in adult].
    Bordeaux medical, 1970, Volume: 3, Issue:10

    Topics: Adult; Aged; Biguanides; Chemical Phenomena; Chemistry; Diabetes Mellitus; Drug Synergism; Ethers; F

1970
[Hypoglycemic sulfamides and biguanides].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1971, Jan-19, Volume: 60, Issue:3

    Topics: Biguanides; Diabetes Mellitus; Humans; Hypoglycemic Agents; Obesity

1971
[Results in diabetic therapy with Silubin retard. 3].
    Medizinische Klinik, 1971, Feb-12, Volume: 66, Issue:7

    Topics: Adolescent; Adult; Biguanides; Cholesterol; Delayed-Action Preparations; Diabetes Mellitus; Diet, Di

1971
[Progress in the therapy of diabetes].
    Wiener medizinische Wochenschrift (1946), 1971, Apr-03, Volume: 121, Issue:14

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aminocaproates; Animals; Biguanides; Blood Glucose; Child; Dia

1971
[Diabetes mellitus. XII. Oral diabetes therapy].
    Zeitschrift fur arztliche Fortbildung, 1971, Feb-01, Volume: 65, Issue:3

    Topics: Administration, Oral; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycem

1971
[Treatment of diabetic fatty liver with Buformin].
    Medizinische Klinik, 1967, Dec-01, Volume: 62, Issue:48

    Topics: Adult; Biguanides; Diabetes Complications; Diet Therapy; Diet, Reducing; Dietary Carbohydrates; Fatt

1967
[Principles for the initial therapy of stable diabetes mellitus].
    Ugeskrift for laeger, 1967, Jul-27, Volume: 129, Issue:30

    Topics: Adult; Age Factors; Aged; Biguanides; Diabetes Mellitus; Diet Therapy; Humans; Middle Aged; Obesity

1967
[The biguanides].
    Il Policlinico. Sezione pratica, 1967, Oct-02, Volume: 74, Issue:40

    Topics: Biguanides; Diabetes Mellitus; Humans; Hypoglycemic Agents; Obesity

1967
[Treatment of diabetes mellitus with dimethylbiguanide. Experience with 280 cases].
    La Clinica terapeutica, 1967, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Biguanides; Child; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents;

1967
[Treatment of obesity in diabetes].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1968, Volume: 13, Issue:8

    Topics: Biguanides; Diabetes Mellitus; Diet, Reducing; Humans; Hypoglycemic Agents; Obesity

1968
[Oral therapy of diabetes].
    La Presse medicale, 1969, Jun-25, Volume: 77, Issue:31

    Topics: Adolescent; Adult; Aged; Biguanides; Blood Glucose; Body Weight; Child; Diabetes Complications; Diab

1969
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