Page last updated: 2024-11-08

biguanides and Necrosis

biguanides has been researched along with Necrosis in 3 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" The MTT assay showed significant dose-response decreases of 500 nm absorbance for all MPS-treated cells."1.38Cytotoxicity and effects on metabolism of contact lens care solutions on human corneal epithelium cells. ( Boost, MV; Cho, P; Choy, CK, 2012)
"These new findings suggest that most of multipurpose solutions are toxic with oxidative stress and apoptosis induction."1.35Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation. ( Baudouin, C; Dutot, M; Rat, P; Warnet, JM, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chekmareva, IA1
Blatun, LA1
Paskhalova, YS1
Mitish, VA1
Paklina, OV1
Terekhova, RP1
Sepeda, P1
Magomedova, SD1
Ushakov, AA1
Sokov, SL1
Choy, CK1
Cho, P1
Boost, MV1
Dutot, M1
Warnet, JM1
Baudouin, C1
Rat, P1

Other Studies

3 other studies available for biguanides and Necrosis

ArticleYear
[Morphological justification of the effectiveness of ultrasonic cavitation with 0.2].
    Khirurgiia, 2019, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; D

2019
Cytotoxicity and effects on metabolism of contact lens care solutions on human corneal epithelium cells.
    Clinical & experimental optometry, 2012, Volume: 95, Issue:2

    Topics: Biguanides; Cell Line; Cell Membrane; Cell Survival; Contact Lens Solutions; Energy Metabolism; Epit

2012
Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Feb-05, Volume: 33, Issue:2

    Topics: Apoptosis; Biguanides; Cell Line; Cell Membrane; Cell Survival; Conjunctiva; Contact Lens Solutions;

2008