biguanides has been researched along with Necrosis in 3 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The MTT assay showed significant dose-response decreases of 500 nm absorbance for all MPS-treated cells." | 1.38 | Cytotoxicity and effects on metabolism of contact lens care solutions on human corneal epithelium cells. ( Boost, MV; Cho, P; Choy, CK, 2012) |
| "These new findings suggest that most of multipurpose solutions are toxic with oxidative stress and apoptosis induction." | 1.35 | Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation. ( Baudouin, C; Dutot, M; Rat, P; Warnet, JM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chekmareva, IA | 1 |
| Blatun, LA | 1 |
| Paskhalova, YS | 1 |
| Mitish, VA | 1 |
| Paklina, OV | 1 |
| Terekhova, RP | 1 |
| Sepeda, P | 1 |
| Magomedova, SD | 1 |
| Ushakov, AA | 1 |
| Sokov, SL | 1 |
| Choy, CK | 1 |
| Cho, P | 1 |
| Boost, MV | 1 |
| Dutot, M | 1 |
| Warnet, JM | 1 |
| Baudouin, C | 1 |
| Rat, P | 1 |
3 other studies available for biguanides and Necrosis
| Article | Year |
|---|---|
[Morphological justification of the effectiveness of ultrasonic cavitation with 0.2].
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; D | 2019 |
Cytotoxicity and effects on metabolism of contact lens care solutions on human corneal epithelium cells.
Topics: Biguanides; Cell Line; Cell Membrane; Cell Survival; Contact Lens Solutions; Energy Metabolism; Epit | 2012 |
Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation.
Topics: Apoptosis; Biguanides; Cell Line; Cell Membrane; Cell Survival; Conjunctiva; Contact Lens Solutions; | 2008 |