Page last updated: 2024-11-08

biguanides and Nails, Ingrown

biguanides has been researched along with Nails, Ingrown in 1 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Nails, Ingrown: Excessive lateral nail growth into the nail fold. Because the lateral margin of the nail acts as a foreign body, inflammation and granulation may result. It is caused by improperly fitting shoes and by improper trimming of the nail.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becerro de Bengoa Vallejo, R1
Losa Iglesias, ME1
Cervera, LA1
Fernández, DS1
Prieto, JP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Preoperative Surgical Scrubbing in Reducing Bacterial Load, Using Chlorhexidine Digluconate (CHX) and Parachlorometaxylenol (PCMX)[NCT02500758]30 participants (Actual)Interventional2015-06-30Completed
Efficacy of Intraoperative Surgical Scrubbing in Reducing Bacterial Load After Nail Removal Surgery[NCT01330706]Phase 450 participants (Actual)Interventional2010-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"Change in the Release of Skin Flora From the Hands From Baseline to 3 Hours After Surgical Scrub Disinfection, Wearing Surgical Gloves (Time Frame- Baseline and 3 Hours)."

Number of colony-forming units (CFU) sampled 3 hours after disinfection by surgical scrubbing using parachlorometaxylenol or clorhexidine digluconate, using surgical gloves. After surgical scrubbing, drying and wearing surgical gloves, the fingertips are rubbed (including that of the thumb) for 1 minute on the base of a Petri dish containing volumes of 1.0 ml and 0.1 ml of undiluted sampling fluid of TSB and 0.1 ml from its 10-1 dilution are plated out for quantitative culture in TSA. (NCT02500758)
Timeframe: 3 hours

InterventionCFU/ml (Mean)
Parachlorometaxylenol4.54
Chlorhexidine Digluconate4.65

"Change in the Release of Skin Flora From the Hands From Baseline to 5 Minutes After Disinfection by Surgical Scrubbing (Time Frame- Baseline and 5 Minutes)."

Number of colony-forming units (CFU) sampled up to 5 minutes after disinfection by surgical scrubbing using parachlorometaxylenol or clorhexidine digluconate. After surgical scrubbing and drying, the fingertips are rubbed (including that of the thumb) for 1 minute on the base of a Petri dish containing volumes of 1.0 ml and 0.1 ml of undiluted sampling fluid of TSB and 0.1 ml from its 10-1 dilution are plated out for quantitative culture in TSA. (NCT02500758)
Timeframe: 5 minutes

InterventionCFU/ml (Mean)
Parachlorometaxylenol3.96
Chlorhexidine Digluconate3.87

Trials

1 trial available for biguanides and Nails, Ingrown

ArticleYear
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011