Page last updated: 2024-11-08

biguanides and Intellectual Disability

biguanides has been researched along with Intellectual Disability in 6 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of a 1% chlorhexidine-containing dental gel on dental plaque and gingival health was evaluated over a period of 6 months using a double-blind procedure."9.04Effects on plaque and gingivitis of a chlorhexidine dental gel in the mentally retarded. ( Barker, DS; Brown, RH; Cutress, TW, 1977)
"The effectiveness of a 1% chlorhexidine-containing dental gel on dental plaque and gingival health was evaluated over a period of 6 months using a double-blind procedure."5.04Effects on plaque and gingivitis of a chlorhexidine dental gel in the mentally retarded. ( Barker, DS; Brown, RH; Cutress, TW, 1977)
"The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin."5.04Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gallagher, IH1
Cutress, TW2
Brown, RH1
Barker, DS1
Russell, BG2
Bay, LM2
Hatle, G1
Gjermo, P1
Usher, PJ1

Trials

4 trials available for biguanides and Intellectual Disability

ArticleYear
Effects on plaque and gingivitis of a chlorhexidine dental gel in the mentally retarded.
    Community dentistry and oral epidemiology, 1977, Volume: 5, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Biguanides; Child; Chlorhexidine; Clinical Trials as Top

1977
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
    Scandinavian journal of dental research, 1978, Volume: 86, Issue:1

    Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial

1978
[Effect of chlorhexidine-containing toothpaste on the gingiva in a group of mentally retarded subjects].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, May-10, Volume: 99, Issue:13

    Topics: Adult; Aged; Biguanides; Chlorhexidine; Dentifrices; Drug Evaluation; Female; Gingiva; Gingivitis; H

1979
Effect of chlorhexidine on dental plaque and gingivitis in mentally retarded children.
    Community dentistry and oral epidemiology, 1975, Volume: 3, Issue:6

    Topics: Adolescent; Biguanides; Child; Chlorhexidine; Clinical Trials as Topic; Dental Plaque; Female; Gingi

1975

Other Studies

2 other studies available for biguanides and Intellectual Disability

ArticleYear
Clinical trial in mentally retarded of chlorhexidine dental gel: bacteriology.
    Community dentistry and oral epidemiology, 1977, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Bacteria; Biguanides; Child; Chlorhexidine; Dental Plaque; Drug Evaluation; Drug

1977
Oral hygiene in mentally handicapped children. A pilot study of the use of chlorhexidine gel.
    British dental journal, 1975, Mar-18, Volume: 138, Issue:6

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Biguanides; Child; Child, Preschool; Dental Calculu

1975