biguanides has been researched along with Infections, Staphylococcal in 29 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study evaluated eradication of methicillin-resistant Staphylococcus aureus (MRSA) from pressure ulcers comparing swabs containing polyhexanide with a cellulose dressing + polyhexanide." | 9.16 | Eradication of methicillin-resistant Staphylococcus aureus in pressure ulcers comparing a polyhexanide-containing cellulose dressing with polyhexanide swabs in a prospective randomized study. ( Andriessen, A; Bruckner, M; Eberlein, T; Payrich, M; Schwarz, C; Wild, T, 2012) |
| "The study evaluated eradication of methicillin-resistant Staphylococcus aureus (MRSA) from pressure ulcers comparing swabs containing polyhexanide with a cellulose dressing + polyhexanide." | 5.16 | Eradication of methicillin-resistant Staphylococcus aureus in pressure ulcers comparing a polyhexanide-containing cellulose dressing with polyhexanide swabs in a prospective randomized study. ( Andriessen, A; Bruckner, M; Eberlein, T; Payrich, M; Schwarz, C; Wild, T, 2012) |
| "Thirty-nine deep partial thickness wounds were created with six wounds assigned to one of six treatment groups: (i) PHMB, (ii) Ringer's solution, (iii) hypochlorous acid/sodium hypochlorite, (iv) sterile water, (v) octenidine dihydrochloride, and (vi) octenilin." | 1.46 | Effectiveness of a polyhexanide irrigation solution on methicillin-resistant Staphylococcus aureus biofilms in a porcine wound model. ( Davis, SC; Gil, J; Harding, A; Higa, A; Parajon, F; Solis, M; Valdes, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 17 (58.62) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Noll, CV | 1 |
| Kilcoyne, I | 1 |
| Nieto, JE | 1 |
| Thio, T | 1 |
| Byrne, BA | 1 |
| Salisbury, AM | 1 |
| Mullin, M | 1 |
| Chen, R | 1 |
| Percival, SL | 1 |
| Kapalschinski, N | 1 |
| Seipp, HM | 1 |
| Kückelhaus, M | 1 |
| Harati, KK | 1 |
| Kolbenschlag, JJ | 1 |
| Daigeler, A | 2 |
| Jacobsen, F | 1 |
| Lehnhardt, M | 2 |
| Hirsch, T | 2 |
| Nakaminami, H | 1 |
| Takadama, S | 1 |
| Okita, M | 1 |
| Sasaki, M | 1 |
| Noguchi, N | 1 |
| Dittmann, K | 1 |
| Schmidt, T | 1 |
| Müller, G | 1 |
| Cuny, C | 1 |
| Holtfreter, S | 1 |
| Troitzsch, D | 1 |
| Pfaff, P | 1 |
| Hübner, NO | 1 |
| Findlay, A | 1 |
| Serrano, C | 1 |
| Punzalan, S | 1 |
| Fan, SL | 1 |
| Baier, G | 1 |
| Cavallaro, A | 1 |
| Vasilev, K | 1 |
| Mailänder, V | 1 |
| Musyanovych, A | 1 |
| Landfester, K | 1 |
| Schmidt, FP | 1 |
| Peivandi, AA | 1 |
| Kohnen, W | 1 |
| Jansen, B | 1 |
| Núñez-Moral, M | 1 |
| Sánchez-Álvarez, E | 1 |
| González-Díaz, I | 1 |
| Peláez-Requejo, B | 1 |
| Fernández-Viña, A | 1 |
| Quintana-Fernández, A | 1 |
| Rodríguez-Suárez, C | 1 |
| van Meurs, SJ | 1 |
| Gawlitta, D | 1 |
| Heemstra, KA | 1 |
| Poolman, RW | 1 |
| Vogely, HC | 1 |
| Kruyt, MC | 1 |
| Schneider, MM | 1 |
| Preiss, S | 1 |
| Harder, LP | 1 |
| Salzmann, GM | 1 |
| Landelle, C | 2 |
| von Dach, E | 2 |
| Haustein, T | 2 |
| Agostinho, A | 2 |
| Renzi, G | 2 |
| Renzoni, A | 1 |
| Pittet, D | 1 |
| Schrenzel, J | 2 |
| François, P | 2 |
| Harbarth, S | 2 |
| Reddersen, K | 1 |
| Finger, S | 1 |
| Zieger, M | 1 |
| Wiegand, C | 1 |
| Buschmann, HJ | 1 |
| Elsner, P | 1 |
| Hipler, UC | 1 |
| Davis, SC | 1 |
| Harding, A | 1 |
| Gil, J | 1 |
| Parajon, F | 1 |
| Valdes, J | 1 |
| Solis, M | 1 |
| Higa, A | 1 |
| Mueller, SW | 1 |
| Krebsbach, LE | 1 |
| Williams, GJ | 1 |
| Denyer, SP | 1 |
| Hosein, IK | 1 |
| Hill, DW | 1 |
| Maillard, JY | 1 |
| Gregg, M | 1 |
| Lacroix, RL | 1 |
| Guyomarch, J | 1 |
| van Nuoï, DN | 1 |
| Beral, L | 1 |
| Donnio, A | 1 |
| Desbois, N | 1 |
| Olive, C | 1 |
| Theodose, R | 1 |
| Merle, H | 1 |
| Wild, T | 1 |
| Bruckner, M | 1 |
| Payrich, M | 1 |
| Schwarz, C | 1 |
| Eberlein, T | 1 |
| Andriessen, A | 1 |
| Kolbenschlag, J | 1 |
| Goertz, O | 1 |
| Behr, B | 1 |
| Motta, GJ | 1 |
| Trigilia, D | 1 |
| Michel, D | 1 |
| Zäch, GA | 1 |
| Tuke, W | 1 |
| Maloney, MH | 1 |
| Smith, CC | 1 |
| Bird, EL | 1 |
| Carey-Smith, KA | 1 |
| Muir, IF | 1 |
| Owen, D | 1 |
| Murphy, J | 1 |
| Forse, SF | 1 |
| Hall, R | 1 |
| Jackson, PS | 1 |
| Sandoe, AJ | 1 |
| Edwards, SJ | 1 |
| Smith, GS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intraoperative Disinfection by Pulse Irrigation With Povidone-Iodine Solution in Spine Surgery[NCT03249363] | 50 participants (Actual) | Interventional | 2010-01-01 | Completed | |||
| Kerlix AMD Gauze Study In A Burn Trauma Unit and Its Effect on Healthcare Associated Infections in Burn Patients[NCT00656708] | 108 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for biguanides and Infections, Staphylococcal
| Article | Year |
|---|---|
[Skin antiseptics in plastic surgery].
Topics: Anti-Infective Agents, Local; Biguanides; Cell Proliferation; Cell Survival; Dose-Response Relations | 2012 |
8 trials available for biguanides and Infections, Staphylococcal
| Article | Year |
|---|---|
Increased peritoneal dialysis exit site infections using topical antiseptic polyhexamethylene biguanide compared to mupirocin: results of a safety interim analysis of an open-label prospective randomized study.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Catheters, Indwelling; Early Termin | 2013 |
Exit-site infection of peritoneal catheter is reduced by the use of polyhexanide. results of a prospective randomized trial.
Topics: Biguanides; Catheter-Related Infections; Catheters, Indwelling; Female; Follow-Up Studies; Humans; M | 2014 |
Randomized, placebo-controlled, double-blind clinical trial to evaluate the efficacy of polyhexanide for topical decolonization of MRSA carriers.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Carrier State; Double-Blin | 2016 |
Determinants of Successful Methicillin-Resistant Staphylococcus aureus Decolonization.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Carrier State; Drug Resistance, B | 2016 |
Eradication of methicillin-resistant Staphylococcus aureus in pressure ulcers comparing a polyhexanide-containing cellulose dressing with polyhexanide swabs in a prospective randomized study.
Topics: Adult; Aged; Bandages; Biguanides; Cellulose; Disease Progression; Female; Health Status Indicators; | 2012 |
The effect of an antimicrobial drain sponge dressing on specific bacterial isolates at tracheostomy sites.
Topics: Adult; Aged; Aged, 80 and over; Bandages; Biguanides; Clinical Nursing Research; Disinfectants; Ente | 2005 |
Sulfamylon acetate in the treatment of pseudomonas pyocyanea infection of burns.
Topics: Adolescent; Adult; Aged; Bandages; Biguanides; Burns; Child; Clinical Trials as Topic; Female; Human | 1969 |
Evaluation of teat-dipping formulations containing a germicidal polymeric biguanide.
Topics: Animals; Biguanides; Cattle; Delayed-Action Preparations; Dermatologic Agents; Disinfectants; Female | 1970 |
20 other studies available for biguanides and Infections, Staphylococcal
| Article | Year |
|---|---|
In vitro efficacy of a 0.2% polyhexamethylene biguanide-impregnated gauze dressing against pathogenic bacterial isolates found in horses.
Topics: Animals; Bandages; Biguanides; Disinfectants; Escherichia coli; Escherichia coli Infections; Horse D | 2021 |
Antibiofilm Efficacy of Polihexanide, Octenidine and Sodium Hypochlorite/Hypochlorous Acid Based Wound Irrigation Solutions against Staphylococcus aureus, Pseudomonas aeruginosa and a Multispecies Biofilm.
Topics: Biguanides; Biofilms; Humans; Hypochlorous Acid; Imines; Pseudomonas aeruginosa; Pyridines; Sodium H | 2022 |
Albumin reduces the antibacterial efficacy of wound antiseptics against Staphylococcus aureus.
Topics: Anti-Infective Agents, Local; Biguanides; Ethylene Glycols; Exudates and Transudates; Humans; Imines | 2017 |
Fast-acting bactericidal activity of olanexidine gluconate against qacA/B-positive methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents, Local; Bacterial Proteins; Biguanides; Chlorhexidine; Glucuronates; Membrane | 2019 |
Susceptibility of livestock-associated methicillin-resistant
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Community-Acquired Infections; Cro | 2019 |
Enzyme responsive hyaluronic acid nanocapsules containing polyhexanide and their exposure to bacteria to prevent infection.
Topics: Anti-Bacterial Agents; Biguanides; Drug Carriers; Escherichia coli; Escherichia coli Infections; Hum | 2013 |
Surgery for acquired cardiovascular disease: antiseptic treatment of contaminated vein grafts.
Topics: Anti-Infective Agents, Local; Antisepsis; Biguanides; Humans; Imines; Operating Rooms; Povidone-Iodi | 2014 |
Selection of an optimal antiseptic solution for intraoperative irrigation: an in vitro study.
Topics: Anti-Infective Agents, Local; Biguanides; Cell Survival; Chlorhexidine; Fibroblasts; Humans; Hydroge | 2014 |
[Destructive chondrolysis following intraarticular application of lavasorb (polihexanid) for treatment of knee empyema].
Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthritis, Infectious; Arthroscopy; Biguanides; Ca | 2015 |
Cytocompatibility testing of cyclodextrin-functionalized antimicrobial textiles-a comprehensive approach.
Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Apoptosis; Bacterial Infections; Biguanides; Bi | 2016 |
Effectiveness of a polyhexanide irrigation solution on methicillin-resistant Staphylococcus aureus biofilms in a porcine wound model.
Topics: Animals; Betaine; Biguanides; Biofilms; Disease Models, Animal; Disinfectants; Methicillin-Resistant | 2017 |
Impact of an antimicrobial-impregnated gauze dressing on surgical site infections including methicillin-resistant Staphylococcus aureus infections.
Topics: Bandages; Biguanides; Cross Infection; Disinfectants; Humans; Length of Stay; Methicillin-Resistant | 2008 |
Limitations of the efficacy of surface disinfection in the healthcare setting.
Topics: Anti-Bacterial Agents; Biguanides; Cross Infection; Disinfectants; Disinfection; Equipment Contamina | 2009 |
Survival of community-associated methicillin-resistant Staphylococcus aureus in 3 different swimming pool environments (chlorinated, saltwater, and biguanide nonchlorinated).
Topics: Biguanides; Chlorine; Colony Count, Microbial; Community-Acquired Infections; Humans; Methicillin-Re | 2010 |
[Infectious keratitis and cosmetic lenses: a five-case retrospective study].
Topics: Abscess; Acanthamoeba Keratitis; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; An | 2010 |
Antiseptic efficacy of disinfecting solutions in suspension test in vitro against methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in pressure sore wounds after spinal cord injury.
Topics: Anti-Infective Agents, Local; Biguanides; Chamomile; Chlorhexidine; Escherichia coli; Escherichia co | 1997 |
Hibiscrub in the control of staphylococcal infection in neonates.
Topics: Biguanides; Chlorhexidine; Drug Evaluation; Humans; Infant, Newborn; Infant, Newborn, Diseases; Skin | 1975 |
Chlorhexidine: a hexachlorophane substitute in the nursery.
Topics: Biguanides; Chlorhexidine; Drug Evaluation; Hexachlorophene; Humans; Infant, Newborn; Infant, Newbor | 1975 |
Bacterial substitution for staphylococcal infection.
Topics: Adult; Ampicillin; Anti-Infective Agents, Local; Bacterial Vaccines; Biguanides; Carrier State; Chlo | 1968 |
An experiment to test the value of hygienic measures in the control of staphylococcal infection of the dairy cow.
Topics: Animals; Biguanides; Cattle; Dairying; Detergents; Disinfectants; Female; Hexachlorophene; Hygiene; | 1970 |