biguanides has been researched along with Infections, Prosthesis-Related in 7 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The exposure of human osteoblasts and endothelial cells to polyhexanide at concentrations with questionable antibacterial activity resulted in severe cell damage whereas exposure to high dosed gentamicin did not." | 1.34 | Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells. ( Eulert, J; Hendrich, C; Ince, A; Jakob, F; Löhr, JF; Schütze, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| O'Donnell, JA | 1 |
| Wu, M | 1 |
| Cochrane, NH | 1 |
| Belay, E | 1 |
| Myntti, MF | 1 |
| James, GA | 1 |
| Ryan, SP | 1 |
| Seyler, TM | 1 |
| Schmidt, FP | 1 |
| Peivandi, AA | 1 |
| Kohnen, W | 1 |
| Jansen, B | 1 |
| Lehner, B | 1 |
| Fleischmann, W | 1 |
| Becker, R | 1 |
| Jukema, GN | 1 |
| Lee, CK | 1 |
| Chua, YP | 1 |
| Saw, A | 1 |
| Ince, A | 1 |
| Schütze, N | 1 |
| Hendrich, C | 1 |
| Jakob, F | 1 |
| Eulert, J | 1 |
| Löhr, JF | 1 |
| Wagner, H | 1 |
| Wagner, M | 2 |
2 trials available for biguanides and Infections, Prosthesis-Related
| Article | Year |
|---|---|
First experiences with negative pressure wound therapy and instillation in the treatment of infected orthopaedic implants: a clinical observational study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Chronic Dis | 2011 |
Antimicrobial gauze as a dressing reduces pin site infection: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Bandages; Biguanides; Bone Nails; Chi-Square Distribution; Child; Child, Pr | 2012 |
5 other studies available for biguanides and Infections, Prosthesis-Related
| Article | Year |
|---|---|
Efficacy of common antiseptic solutions against clinically relevant microorganisms in biofilm.
Topics: Acetic Acid; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement; Benzalk | 2021 |
Surgery for acquired cardiovascular disease: antiseptic treatment of contaminated vein grafts.
Topics: Anti-Infective Agents, Local; Antisepsis; Biguanides; Humans; Imines; Operating Rooms; Povidone-Iodi | 2014 |
Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells.
Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement | 2007 |
[Infected hip joint prosthesis. Viewpoints for 1-stage and 2-stage prosthesis exchange].
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Debridement; Hip Prosthesis; Humans | 1995 |
[Local antisepsis in infected total hip endoprosthesis].
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Debridement; Female; Hemat | 1995 |