Page last updated: 2024-11-08

biguanides and Infection, Postoperative Wound

biguanides has been researched along with Infection, Postoperative Wound in 52 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Research Excerpts

ExcerptRelevanceReference
"The prevalence of surgical site infection (SSI) remains higher in gastrointestinal surgery than in other surgeries."2.90Comparison of olanexidine versus povidone-iodine for preventing surgical site infection in gastrointestinal surgery: study protocol for a multicentre, single-blind, randomised controlled clinical trial. ( Abe, Y; Fukuda, K; Harada, H; Hirukawa, K; Hori, S; Irino, T; Ishida, T; Isobe, Y; Kawakubo, H; Kitagawa, Y; Kitago, M; Kondo, T; Maeda, Y; Mayanagi, S; Nakamura, R; Obara, H; Okabayashi, K; Oshima, G; Sato, Y; Sekimoto, Y; Shinoda, M; Shito, M; Takeuchi, M; Tsuruta, M; Wada, N; Yagi, H; Yokose, T, 2019)
"Postoperative surgical site infection (SSI) is one of the most common hospital infections and contributes substantially to postoperative morbidity and mortality."2.84Intraoperative wound irrigation to prevent surgical site infection after laparotomy (IOWISI): study protocol for a randomized controlled trial. ( Friess, H; Goess, R; Kehl, V; Mueller, TC; Nitsche, U; Reim, D; Schirren, R; Schossow, B, 2017)
"Notably, the respective incidences of surgical site infection except anastomotic leakage were 1."1.72Propensity-matched analysis of the efficacy of olanexidine gluconate versus chlorhexidine-alcohol as an antiseptic agent in thoracic esophagectomy. ( Daiko, H; Fujita, T; Fujiwara, H; Kojima, T; Okada, N; Sato, K; Sato, T, 2022)
"We examined surgical site infection rate after disinfection using PVP-I and OLG, length of hospitalization stay (days) after surgery, adverse events associated with antiseptics, and additional medical costs associated with adverse events caused by antiseptics."1.62Examination of the efficacy of olanexidine gluconate for surgical site infections in colorectal cancer elective surgery. ( Habiro, T; Hayashi, K; Ishii, KI; Kojima, K; Nakamura, T; Waraya, M, 2021)
" The increasing incidence of hemangiosarcomas highly probably resulted from increased endothelial proliferation, triggered by the exceedingly high dosage fed, because PHMB is not genotoxic and there is no evidence for epigenetic effects."1.51Re-evaluation of polihexanide use in wound antisepsis in order to clarify ambiguities of two animal studies. ( Assadian, O; Dissemond, J; Eberlein, T; Kramer, A; Müller, G, 2019)
"But olanexidine was significantly more effective at both time points than chlorhexidine and povidone-iodine when applied after the site was contaminated with blood."1.46Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. ( Hagi, A; Imamura, T; Inoue, Y; Nakata, H; Nii, T; Tsubotani, Y, 2017)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199015 (28.85)18.7374
1990's3 (5.77)18.2507
2000's5 (9.62)29.6817
2010's18 (34.62)24.3611
2020's11 (21.15)2.80

Authors

AuthorsStudies
Kojima, K1
Nakamura, T1
Habiro, T1
Waraya, M1
Hayashi, K2
Ishii, KI1
Fujita, T2
Okada, N1
Sato, T1
Sato, K1
Fujiwara, H1
Kojima, T1
Daiko, H1
Kubo, N1
Furusawa, N1
Takeuchi, D1
Imai, S1
Masuo, H1
Umemura, K1
Terada, M1
Jalalzadeh, H1
Groenen, H1
Buis, DR1
Dreissen, YE1
Goosen, JH1
Ijpma, FF1
van der Laan, MJ1
Schaad, RR1
Segers, P1
van der Zwet, WC1
Griekspoor, M1
Harmsen, WJ1
Wolfhagen, N1
Boermeester, MA1
Asukai, M1
Ohishi, T1
Suzuki, D1
Nishida, T1
Sugiura, K1
Matsuyama, Y1
Strobel, RM1
Leonhardt, M1
Krochmann, A1
Neumann, K1
Speichinger, F1
Hartmann, L1
Lee, LD1
Beyer, K1
Daum, S1
Kreis, ME1
Lauscher, JC1
Willy, C2
Vogt, D1
Obara, H2
Takeuchi, M2
Kawakubo, H2
Shinoda, M2
Okabayashi, K2
Sekimoto, Y2
Maeda, Y2
Kondo, T2
Sato, Y2
Kitagawa, Y2
Yamamoto, M1
Hara, K1
Sugezawa, K1
Uejima, C1
Tanio, A1
Tada, Y1
Shishido, Y1
Miyatani, K1
Hanaki, T1
Kihara, K1
Matsunaga, T1
Tokuyasu, N1
Takano, S1
Sakamoto, T1
Honjo, S1
Fujiwara, Y1
Wandhoff, B1
Schröder, C1
Nöth, U1
Krause, R1
Schmidt, B1
David, S1
Scheller, EE1
Jahn, F1
Behnke, M1
Gastmeier, P1
Kramer, TS1
Noll, CV1
Kilcoyne, I1
Nieto, JE1
Thio, T1
Byrne, BA1
Saeg, F1
Schoenbrunner, AR1
Janis, JE1
Nakata, H1
Tsubotani, Y1
Nii, T1
Hagi, A1
Inoue, Y1
Imamura, T1
Mueller, TC1
Nitsche, U1
Kehl, V1
Schirren, R1
Schossow, B1
Goess, R1
Friess, H1
Reim, D1
Kramer, A1
Eberlein, T1
Müller, G1
Dissemond, J1
Assadian, O1
Mayanagi, S1
Irino, T1
Fukuda, K1
Nakamura, R1
Wada, N1
Kitago, M1
Yagi, H1
Abe, Y1
Oshima, G1
Hori, S1
Tsuruta, M1
Ishida, T1
Yokose, T1
Hirukawa, K1
Isobe, Y1
Harada, H1
Shito, M1
Back, DA1
Scheuermann-Poley, C1
Dumville, JC2
Gray, TA2
Walter, CJ2
Sharp, CA2
Page, T2
Schneider, MM1
Preiss, S1
Harder, LP1
Salzmann, GM1
Ceviker, K1
Canikoglu, M1
Tatlıoglu, S1
Bagdatli, Y1
Dettmers, R1
Brekelmans, W1
Leijnen, M1
van der Burg, B1
Ritchie, E1
Saleh, K1
Sonesson, A1
Persson, K1
Riesbeck, K1
Schmidtchen, A1
Macefield, R1
Blencowe, N1
Milne, TK1
Reeves, BC1
Blazeby, J1
Mueller, SW1
Krebsbach, LE1
Kuznetsov, NA1
Nikitin, VG1
Teleshova, EB1
Mil'chakov, AA1
Becerro de Bengoa Vallejo, R2
Losa Iglesias, ME2
Cervera, LA1
Fernández, DS1
Prieto, JP1
Kolbenschlag, J1
Goertz, O1
Behr, B1
Daigeler, A1
Lehnhardt, M1
Hirsch, T1
Alou Cervera, L1
Sevillano Fernández, D1
Prieto Prieto, J1
Nielsen, AM1
Andriessen, A1
Röhner, E1
Hoff, P1
Pfitzner, T1
Seeger, JB1
Buttgereit, F1
Perka, C1
Matziolis, G1
Gerli, S1
Bavetta, F1
Di Renzo, GC1
Fabry, W2
Trampenau, C1
Bettag, C2
Handschin, AE1
Lettgen, B1
Huber, FX1
Hillmeier, J1
Kock, HJ2
Salas Campos, L1
Gómez Ferrero, O1
Estudillo Pérez, V1
Fernández Mansilla, M1
Willenegger, H1
Pfister, A1
Ochsner, PE1
Schmit-Neuerburg, KP1
Schlickewei, W1
Hanke, J1
Renzing-Köhler, K1
Hirche, H1
Addy, M1
Dolby, AE1
Tanphiphat, C1
Udomchanya, S1
Wacharasin, T1
Suwanpen, T1
Panichabhongse, V1
Vajrabukka, C1
Roszkowski, I1
Leibschang, J1
Kowalczuk, H1
Kalowski, M1
Kedzia, A1
Szczygiel, B1
Switka, S1
Wencel, J1
Etsch, B1
Nielsen, ML1
Raahave, D3
Stage, JG1
Justesen, T1
Roth, B1
Baltzer, K1
Speller, DC1
Stephens, ME1
Viant, AC1
Honigman, JL1
Rushton, A1
Bassett, DC1
Stokes, KJ1
Thomas, WR1
Wright, JE1
Hennessy, EJ1
Bissett, RL1
Robinson, PW1
Lowbury, EJ1
Lilly, HA1
Crosfill, M1
Hall, R1
London, D1
Calman, KC1
Kennedy, F1
Meudell, CM1
Sleigh, JD1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Reduction of Postoperative Wound Infections by Antiseptica?[NCT04055233]Phase 3456 participants (Actual)Interventional2015-02-01Completed
Micro/Nanobubbles (MNBs) and Wound Therapy: A Pilot Study Involving a Novel Oxygen Delivery System for Treatment of Acute and Chronic Wounds[NCT05169814]Early Phase 140 participants (Anticipated)Interventional2021-10-09Recruiting
The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections[NCT05392400]Phase 21,000 participants (Anticipated)Interventional2023-02-07Not yet recruiting
Effectiveness of Preoperative Surgical Scrubbing in Reducing Bacterial Load, Using Chlorhexidine Digluconate (CHX) and Parachlorometaxylenol (PCMX)[NCT02500758]30 participants (Actual)Interventional2015-06-30Completed
Efficacy of Intraoperative Surgical Scrubbing in Reducing Bacterial Load After Nail Removal Surgery[NCT01330706]Phase 450 participants (Actual)Interventional2010-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"Change in the Release of Skin Flora From the Hands From Baseline to 3 Hours After Surgical Scrub Disinfection, Wearing Surgical Gloves (Time Frame- Baseline and 3 Hours)."

Number of colony-forming units (CFU) sampled 3 hours after disinfection by surgical scrubbing using parachlorometaxylenol or clorhexidine digluconate, using surgical gloves. After surgical scrubbing, drying and wearing surgical gloves, the fingertips are rubbed (including that of the thumb) for 1 minute on the base of a Petri dish containing volumes of 1.0 ml and 0.1 ml of undiluted sampling fluid of TSB and 0.1 ml from its 10-1 dilution are plated out for quantitative culture in TSA. (NCT02500758)
Timeframe: 3 hours

InterventionCFU/ml (Mean)
Parachlorometaxylenol4.54
Chlorhexidine Digluconate4.65

"Change in the Release of Skin Flora From the Hands From Baseline to 5 Minutes After Disinfection by Surgical Scrubbing (Time Frame- Baseline and 5 Minutes)."

Number of colony-forming units (CFU) sampled up to 5 minutes after disinfection by surgical scrubbing using parachlorometaxylenol or clorhexidine digluconate. After surgical scrubbing and drying, the fingertips are rubbed (including that of the thumb) for 1 minute on the base of a Petri dish containing volumes of 1.0 ml and 0.1 ml of undiluted sampling fluid of TSB and 0.1 ml from its 10-1 dilution are plated out for quantitative culture in TSA. (NCT02500758)
Timeframe: 5 minutes

InterventionCFU/ml (Mean)
Parachlorometaxylenol3.96
Chlorhexidine Digluconate3.87

Reviews

7 reviews available for biguanides and Infection, Postoperative Wound

ArticleYear
Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis.
    The Lancet. Microbe, 2022, Volume: 3, Issue:10

    Topics: Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Ethanol; GRADE Approach; Humans; Incidence;

2022
Evidence-Based Wound Irrigation: Separating Fact from Fiction.
    Plastic and reconstructive surgery, 2021, Oct-01, Volume: 148, Issue:4

    Topics: Biguanides; Evidence-Based Medicine; Humans; Intraoperative Care; Negative-Pressure Wound Therapy; P

2021
Recommendations on negative pressure wound therapy with instillation and antimicrobial solutions - when, where and how to use: what does the evidence show?
    International wound journal, 2013, Volume: 10 Suppl 1

    Topics: Acetic Acid; Anti-Infective Agents, Local; Biguanides; Cross Infection; Evidence-Based Medicine; Hum

2013
Dressings for the prevention of surgical site infection.
    The Cochrane database of systematic reviews, 2014, Sep-01, Issue:9

    Topics: Bandages; Bandages, Hydrocolloid; Biguanides; Humans; Randomized Controlled Trials as Topic; Surgica

2014
Dressings for the prevention of surgical site infection.
    The Cochrane database of systematic reviews, 2016, 12-20, Volume: 12

    Topics: Alginates; Bandages; Bandages, Hydrocolloid; Biguanides; Disinfectants; Humans; Randomized Controlle

2016
[Skin antiseptics in plastic surgery].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2012, Volume: 44, Issue:4

    Topics: Anti-Infective Agents, Local; Biguanides; Cell Proliferation; Cell Survival; Dose-Response Relations

2012
[Local antiseptics in surgery--rebirth and advances].
    Unfallchirurgie, 1994, Volume: 20, Issue:2

    Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Biguanides; Fracture Fixation, Inter

1994

Trials

17 trials available for biguanides and Infection, Postoperative Wound

ArticleYear
Reduction of Postoperative Wound Infections by Antiseptica (RECIPE)?: A Randomized Controlled Trial.
    Annals of surgery, 2020, Volume: 272, Issue:1

    Topics: Biguanides; Digestive System Surgical Procedures; Disinfectants; Female; Humans; Intraoperative Care

2020
Aqueous olanexidine versus aqueous povidone-iodine for surgical skin antisepsis on the incidence of surgical site infections after clean-contaminated surgery: a multicentre, prospective, blinded-endpoint, randomised controlled trial.
    The Lancet. Infectious diseases, 2020, Volume: 20, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Antisepsis; Biguanides; Dermatologic A

2020
Disinfection with single or double usage of new antiseptic olanexidine gluconate in general surgery: a randomized study.
    Langenbeck's archives of surgery, 2020, Volume: 405, Issue:8

    Topics: Anti-Infective Agents, Local; Biguanides; Disinfection; Glucuronates; Humans; Povidone-Iodine; Surgi

2020
Intraoperative wound irrigation to prevent surgical site infection after laparotomy (IOWISI): study protocol for a randomized controlled trial.
    Trials, 2017, 09-04, Volume: 18, Issue:1

    Topics: Anti-Infective Agents, Local; Biguanides; Clinical Protocols; Double-Blind Method; Germany; Humans;

2017
Comparison of olanexidine versus povidone-iodine for preventing surgical site infection in gastrointestinal surgery: study protocol for a multicentre, single-blind, randomised controlled clinical trial.
    BMJ open, 2019, 05-28, Volume: 9, Issue:5

    Topics: Anti-Infective Agents, Local; Biguanides; Digestive System Surgical Procedures; Humans; Povidone-Iod

2019
Reducing the pathogen burden and promoting healing with polyhexanide in non-healing wounds: a prospective study.
    Journal of wound care, 2015, Volume: 24, Issue:12

    Topics: Aged; Anti-Infective Agents, Local; Bacterial Infections; Biguanides; C-Reactive Protein; Cohort Stu

2015
Can dressings soaked with polyhexanide reduce bacterial loads in full-thickness skin grafting? A randomized controlled trial.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:6

    Topics: Aged; Aged, 80 and over; Autografts; Bacterial Load; Bandages; Biguanides; Disinfectants; Double-Bli

2016
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Mic

2011
Efficacy of intraoperative antiseptic scrub after nail removal surgery.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27, Issue:7

    Topics: Anti-Infective Agents, Local; Biguanides; Humans; Intraoperative Care; Nails; Prospective Studies; S

2013
Prospective cohort study on surgical wounds comparing a polyhexanide-containing biocellulose dressing with a dialkyl-carbamoyl-chloride-containing hydrophobic dressing.
    Advances in skin & wound care, 2012, Volume: 25, Issue:9

    Topics: Aged; Anti-Infective Agents; Bandages; Biguanides; Biocompatible Materials; Cohort Studies; Diabetic

2012
Antisepsis regimen in the surgical treatment of HPV generated cervical lesions: polyhexamethylene biguanide vs chlorhexidine. A randomized, double blind study.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:14

    Topics: Administration, Intravaginal; Adult; Anti-Infective Agents, Local; Antisepsis; Biguanides; Chlorhexi

2012
Bacterial decontamination of surgical wounds treated with Lavasept.
    International journal of hygiene and environmental health, 2006, Volume: 209, Issue:6

    Topics: Bacterial Infections; Biguanides; Colony Count, Microbial; Disinfectants; Double-Blind Method; Gram-

2006
[Effectiveness of an improved antiseptic in treatment of contaminated soft tissue wounds].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2001, Volume: 72, Issue:1

    Topics: Adult; Aged; Anti-Infective Agents, Local; Bacterial Infections; Biguanides; Double-Blind Method; Fe

2001
The use of chlorhexidine mouthwash compared with a periodontal dressing following the gingivectomy procedure.
    Journal of clinical periodontology, 1976, Volume: 3, Issue:1

    Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Female; Follow-Up Studies; Gingival Pock

1976
Use of 4 per cent chlorhexidine detergent solution (Hibiscrub) and other methods of skin disinfection.
    British medical journal, 1973, Mar-03, Volume: 1, Issue:5852

    Topics: Analysis of Variance; Anti-Infective Agents, Local; Bandages; Biguanides; Cresols; Detergents; Ethan

1973
The use of chlorhexidine antisepsis in contaminated surgical wounds.
    The British journal of surgery, 1969, Volume: 56, Issue:12

    Topics: Appendectomy; Biguanides; Clinical Trials as Topic; Hospitalization; Humans; Sodium Chloride; Surgic

1969
Prophylaxis of wound infection.
    British medical journal, 1971, Oct-23, Volume: 4, Issue:5781

    Topics: Anti-Bacterial Agents; Biguanides; Clinical Trials as Topic; Humans; Placebos; Surgical Wound Infect

1971

Other Studies

28 other studies available for biguanides and Infection, Postoperative Wound

ArticleYear
Examination of the efficacy of olanexidine gluconate for surgical site infections in colorectal cancer elective surgery.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2021, Volume: 27, Issue:12

    Topics: Anti-Infective Agents, Local; Biguanides; Colorectal Neoplasms; Glucuronates; Humans; Methicillin-Re

2021
Propensity-matched analysis of the efficacy of olanexidine gluconate versus chlorhexidine-alcohol as an antiseptic agent in thoracic esophagectomy.
    BMC surgery, 2022, Jan-22, Volume: 22, Issue:1

    Topics: Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Cohort Studies; Esophagectomy; Glucuronates

2022
Clinical study of a new skin antiseptic olanexidine gluconate in gastrointestinal cancer surgery.
    BMC surgery, 2022, May-19, Volume: 22, Issue:1

    Topics: Anti-Infective Agents, Local; Biguanides; Digestive System Surgical Procedures; Gastrointestinal Neo

2022
Olanexidine gluconate versus povidone-iodine for preventing surgical-site infection in orthopaedic surgery: A retrospective study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2019, Volume: 24, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Female; Glucuronates; Huma

2019
Should olanexidine be used routinely for surgical skin antisepsis?
    The Lancet. Infectious diseases, 2020, Volume: 20, Issue:11

    Topics: Antisepsis; Biguanides; Humans; Incidence; Povidone-Iodine; Prospective Studies; Surgical Wound Infe

2020
Efficacy of universal preoperative decolonization with Polyhexanide in primary joint arthroplasty on surgical site infections. A multicenter before-and after-study.
    Antimicrobial resistance and infection control, 2020, 11-30, Volume: 9, Issue:1

    Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Biguanides; Female; Humans; M

2020
In vitro efficacy of a 0.2% polyhexamethylene biguanide-impregnated gauze dressing against pathogenic bacterial isolates found in horses.
    Veterinary surgery : VS, 2021, Volume: 50, Issue:4

    Topics: Animals; Bandages; Biguanides; Disinfectants; Escherichia coli; Escherichia coli Infections; Horse D

2021
Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys.
    Journal of medical microbiology, 2017, Volume: 66, Issue:5

    Topics: Acinetobacter baumannii; Administration, Topical; Animals; Anti-Infective Agents, Local; Biguanides;

2017
Re-evaluation of polihexanide use in wound antisepsis in order to clarify ambiguities of two animal studies.
    Journal of wound care, 2019, Apr-02, Volume: 28, Issue:4

    Topics: Animals; Anti-Infective Agents, Local; Biguanides; Consensus; Disease Models, Animal; Risk Assessmen

2019
[Destructive chondrolysis following intraarticular application of lavasorb (polihexanid) for treatment of knee empyema].
    MMW Fortschritte der Medizin, 2015, Apr-30, Volume: 157, Issue:8

    Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthritis, Infectious; Arthroscopy; Biguanides; Ca

2015
Negative Pressure Wound Therapy With Instillation and Dwell Time Used to Treat Infected Orthopedic Implants: A 4-patient Case Series.
    Ostomy/wound management, 2016, Volume: 62, Issue:9

    Topics: Aged; Anti-Bacterial Agents; Biguanides; Female; Humans; Internal Fixators; Male; Middle Aged; Negat

2016
Impact of an antimicrobial-impregnated gauze dressing on surgical site infections including methicillin-resistant Staphylococcus aureus infections.
    American journal of infection control, 2008, Volume: 36, Issue:9

    Topics: Bandages; Biguanides; Cross Infection; Disinfectants; Humans; Length of Stay; Methicillin-Resistant

2008
[Biodegradable implants and antiseptics for the treatment of postoperative osteomyelitis].
    Khirurgiia, 2009, Issue:5

    Topics: Absorbable Implants; Administration, Topical; Adult; Aged; Apatites; Biguanides; Collagen; Disinfect

2009
Limited use of antiseptics in septic surgery.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012, Volume: 25, Issue:5

    Topics: Annexin A5; Anti-Infective Agents, Local; Apoptosis; Biguanides; Caspases; Cells, Cultured; Chlorhex

2012
[Preventing nosocomial infections. Dressings soaked in polyhexamethylene biguanide (PHMB)].
    Revista de enfermeria (Barcelona, Spain), 2006, Volume: 29, Issue:6

    Topics: Anti-Bacterial Agents; Bandages; Biguanides; Cross Infection; Humans; Surgical Wound Infection

2006
[Experiences with closed irrigation-suction drainage and simultaneous administration of an antiseptic].
    Der Unfallchirurg, 1993, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Local; Big

1993
Wound infection in emergency appendectomy: a prospective trial with topical ampicillin and savlon.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1976, Volume: 59, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Aged; Ampicillin; Appendectomy; Biguanides; Cetrimonium

1976
[Clinical and laboratory evaluation of Hibiscrub].
    Ginekologia polska, 1975, Volume: 46, Issue:5

    Topics: Biguanides; Chlorhexidine; Cross Infection; Disinfectants; Female; Humans; Personnel, Hospital; Preg

1975
[Clinical evaluation of Hibisol, an aerosol disinfectant].
    Otolaryngologia polska = The Polish otolaryngology, 1975, Volume: 29, Issue:2

    Topics: Aerosols; Antisepsis; Biguanides; Chlorhexidine; Disinfectants; Humans; Surgical Wound Infection

1975
[Chlorhexidine--a colored 0.5 solution in 70% alcohol as aerosol of Polish production].
    Polski przeglad chirurgiczny, 1975, Volume: 47, Issue:11

    Topics: Aerosols; Bacteria; Biguanides; Chlorhexidine; Humans; Solutions; Surgical Wound Infection

1975
Anaerobic and aerobic skin bacteria before and after skin-disinfection with chlorhexidine: an experimental study in volunteers.
    Journal of clinical pathology, 1975, Volume: 28, Issue:10

    Topics: Adolescent; Adult; Aged; Bacteria; Biguanides; Cetrimonium Compounds; Chlorhexidine; Disinfection; E

1975
[Preventive intraoperative irrigation in wound management with Lavasept. Report of experiences with 1,610 cases].
    Zeitschrift fur Unfallchirurgie und Versicherungsmedizin : offizielles Organ der Schweizerischen Gesellschaft fur Unfallmedizin und Berufskrankheiten = Revue de traumatologie et d'assicurologie : organe officiel de la Societe suisse de ..., 1990, Volume: 83, Issue:4

    Topics: Anti-Infective Agents, Local; Biguanides; Humans; Surgical Wound Infection; Therapeutic Irrigation;

1990
Hospital infection by Pseudomonas cepacia.
    Lancet (London, England), 1971, Apr-17, Volume: 1, Issue:7703

    Topics: Anti-Infective Agents, Local; Biguanides; Cross Infection; Disease Outbreaks; Humans; Pseudomonas; P

1971
Prevention of wound infection in acute appendicitis.
    Lancet (London, England), 1973, Sep-08, Volume: 2, Issue:7828

    Topics: Anti-Infective Agents, Local; Appendectomy; Appendicitis; Biguanides; Humans; Postoperative Complica

1973
Wound infection with Pseudomonas multivorans. A water-borne contaminant of disinfectant solutions.
    Lancet (London, England), 1970, Jun-06, Volume: 1, Issue:7658

    Topics: Adolescent; Adult; Aged; Biguanides; Cross Infection; Disinfectants; Drug Resistance, Microbial; Fem

1970
Antisepsis of the operation site with aqueous cetrimide/chlorhexidine and chlorhexidine in alcohol.
    Acta chirurgica Scandinavica, 1974, Volume: 140, Issue:8

    Topics: Agar; Anti-Infective Agents, Local; Antisepsis; Biguanides; Bromates; Bromine; Citrobacter; Colostom

1974
Aseptic barriers of plastic to prevent bacterial contamination of operation wounds.
    Acta chirurgica Scandinavica, 1974, Volume: 140, Issue:8

    Topics: Anti-Infective Agents, Local; Asepsis; Bacillus; Biguanides; Bromates; Disinfection; Disposable Equi

1974
A continuing assessment of wound infection rates from January 1967 to June 1970, with a study of two methods of preoperative skin preparation.
    The Australian and New Zealand journal of surgery, 1973, Volume: 42, Issue:4

    Topics: Biguanides; Emergencies; Ethyl Ethers; Herniorrhaphy; Humans; Iodine; Preoperative Care; Skin; Soaps

1973