Page last updated: 2024-11-08

biguanides and Glioma

biguanides has been researched along with Glioma in 4 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The pharmacological characteristics of 5-HT3 receptor (5-hydroxytryptamine3 receptor) recognition sites labelled with [3H]-(S)-zacopride and [3H]granisetron in membranes prepared from NG108-15 neuroblastoma-glioma cells were directly compared to investigate further differences in the binding characteristics of these two radioligands."7.68Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. ( Barnes, JM; Barnes, NM, 1993)
"The pharmacological characteristics of 5-HT3 receptor (5-hydroxytryptamine3 receptor) recognition sites labelled with [3H]-(S)-zacopride and [3H]granisetron in membranes prepared from NG108-15 neuroblastoma-glioma cells were directly compared to investigate further differences in the binding characteristics of these two radioligands."3.68Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. ( Barnes, JM; Barnes, NM, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Barbieri, F1
Bosio, AG1
Pattarozzi, A1
Tonelli, M1
Bajetto, A1
Verduci, I1
Cianci, F1
Cannavale, G1
Palloni, LMG1
Francesconi, V1
Thellung, S1
Fiaschi, P1
Mazzetti, S1
Schenone, S1
Balboni, B1
Girotto, S1
Malatesta, P1
Daga, A1
Zona, G1
Mazzanti, M1
Florio, T1
Barnes, JM1
Barnes, NM1
Rondé, P1
Nichols, RA1
Boess, FG1
SepĂșlveda, MI1
Lummis, SC1
Martin, IL1

Other Studies

4 other studies available for biguanides and Glioma

ArticleYear
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives.
    Journal of experimental & clinical cancer research : CR, 2022, Feb-08, Volume: 41, Issue:1

    Topics: Biguanides; Cell Line, Tumor; Chloride Channels; Glioblastoma; Glioma; Humans; Neoplastic Stem Cells

2022
Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron.
    Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10

    Topics: Animals; Benzamides; Biguanides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bri

1993
High calcium permeability of serotonin 5-HT3 receptors on presynaptic nerve terminals from rat striatum.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Animals; Biguanides; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability

1998
5-HT3 receptors in NG108-15 neuroblastoma x glioma cells: effect of the novel agonist 1-(m-chlorophenyl)-biguanide.
    Neuropharmacology, 1992, Volume: 31, Issue:6

    Topics: Animals; Biguanides; Binding, Competitive; Evoked Potentials; Glioma; Hybrid Cells; Imidazoles; Indo

1992