biguanides has been researched along with Eye Infections, Fungal in 17 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Eye Infections, Fungal: Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "00045%, was associated with the Fusarium keratitis epidemic of 2004 to 2006." | 7.78 | Pan-antimicrobial failure of alexidine as a contact lens disinfectant when heated in Bausch & Lomb plastic containers: implications for the worldwide Fusarium keratitis epidemic of 2004 to 2006. ( Bullock, JD; Elder, BL; Khalaf, SZ; Khamis, HJ; Warwar, RE, 2012) |
| "00045%, was associated with the Fusarium keratitis epidemic of 2004 to 2006." | 3.78 | Pan-antimicrobial failure of alexidine as a contact lens disinfectant when heated in Bausch & Lomb plastic containers: implications for the worldwide Fusarium keratitis epidemic of 2004 to 2006. ( Bullock, JD; Elder, BL; Khalaf, SZ; Khamis, HJ; Warwar, RE, 2012) |
| "Microsporidial keratoconjunctivitis is common in India." | 1.38 | Diagnosis, clinical features and treatment outcome of microsporidial keratoconjunctivitis. ( Das, S; Kar, S; Nayak, SS; Sahu, SK; Sharma, S, 2012) |
| "Fusarium keratitis is a severe ocular infection." | 1.38 | Benefit of polyhexamethylene biguanide in Fusarium keratitis. ( Behrens-Baumann, W; Haeberle, H; Hofmüller, W; Seibold, M; Tammer, I; Tintelnot, K; Walter, S; Wecke, T, 2012) |
| "Acanthamoeba keratitis is a rare but severe corneal infection which, despite improvements in diagnosis and treatment, still culminates in prolonged morbidity and significant loss of visual acuity." | 1.34 | [Acanthamoeba keratitis: about the first two Tunisian cases]. ( Ayadi, A; Ben Salah, S; Ben Zina, Z; Cheikrouhou, F; Colin, J; Feki, J; Makni, F; Mlik, M, 2007) |
| "From July 1996 to March 1997, three cases of Acanthamoeba keratitis combined with fungal infection were diagnosed and treated at our ophthalmic department." | 1.30 | Treatment of Acanthamoeba keratitis combined with fungal infection with polyhexamethylene biguanide. ( Sheu, MM; Tien, SH, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Roszkowska, AM | 1 |
| Severo, AA | 1 |
| Biondo, C | 1 |
| Postorino, EI | 1 |
| Inferrera, L | 1 |
| Aragona, P | 1 |
| Bullock, JD | 2 |
| Elder, BL | 2 |
| Warwar, RE | 2 |
| Snyder, SA | 1 |
| Sizemore, IE | 1 |
| Sahu, SK | 4 |
| Das, S | 4 |
| Sharma, S | 4 |
| Vemuganti, GK | 2 |
| Nayak, SS | 2 |
| Kar, S | 2 |
| Sanjay, S | 1 |
| Rebong, RA | 1 |
| Santaella, RM | 1 |
| Goldhagen, BE | 1 |
| Majka, CP | 1 |
| Perfect, JR | 1 |
| Steinbach, WJ | 1 |
| Afshari, NA | 1 |
| Khamis, HJ | 1 |
| Khalaf, SZ | 1 |
| Behrens-Baumann, W | 1 |
| Seibold, M | 1 |
| Hofmüller, W | 1 |
| Walter, S | 1 |
| Haeberle, H | 1 |
| Wecke, T | 1 |
| Tammer, I | 1 |
| Tintelnot, K | 1 |
| Taneja, M | 1 |
| Ashar, JN | 1 |
| Mathur, A | 1 |
| Nalamada, S | 1 |
| Garg, P | 1 |
| Clavet, CR | 1 |
| Chaput, MP | 1 |
| Silverman, MD | 1 |
| Striplin, M | 1 |
| Shoff, ME | 1 |
| Lucas, AD | 1 |
| Hitchins, VM | 1 |
| Eydelman, MB | 1 |
| Panda, A | 1 |
| Ahuja, R | 1 |
| Biswas, NR | 1 |
| Satpathy, G | 1 |
| Khokhar, S | 1 |
| Ben Salah, S | 1 |
| Makni, F | 1 |
| Cheikrouhou, F | 1 |
| Ben Zina, Z | 1 |
| Mlik, M | 1 |
| Feki, J | 1 |
| Colin, J | 1 |
| Ayadi, A | 1 |
| Fiscella, RG | 2 |
| Moshifar, M | 1 |
| Messick, CR | 2 |
| Pendland, SL | 2 |
| Chandler, JW | 1 |
| Viana, M | 1 |
| Moshirfar, M | 1 |
| Losnedahl, KJ | 1 |
| Schriever, CA | 1 |
| Schreckenberger, PC | 1 |
| Tien, SH | 1 |
| Sheu, MM | 1 |
2 reviews available for biguanides and Eye Infections, Fungal
| Article | Year |
|---|---|
Combined Phialemonium curvatum and Acanthamoeba Keratitis: The Importance of Early Diagnosis and Specific Therapy.
Topics: Acanthamoeba Keratitis; Administration, Ophthalmic; Anti-Bacterial Agents; Antifungal Agents; Ascomy | 2021 |
Acanthamoeba keratitis presenting as a plaque.
Topics: Acanthamoeba Keratitis; Atropine; Biguanides; Ciprofloxacin; Cornea; Diagnosis, Differential; Drug A | 2008 |
1 trial available for biguanides and Eye Infections, Fungal
| Article | Year |
|---|---|
Clinical trial of 0.02% polyhexamethylene biguanide versus placebo in the treatment of microsporidial keratoconjunctivitis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Child; Disinfectant | 2010 |
14 other studies available for biguanides and Eye Infections, Fungal
| Article | Year |
|---|---|
Mechanism of drug failure in fusarium keratitis, 2004-2006.
Topics: Biguanides; Chromatography, Liquid; Contact Lens Solutions; Eye Infections, Fungal; Fusariosis; Fusa | 2014 |
Clinical trial of 0.02% polyhexamethylene biguanide versus placebo in the treatment of microsporidial keratoconjunctivitis.
Topics: Administration, Topical; Biguanides; Disinfectants; Double-Blind Method; Eye Infections, Fungal; Hum | 2011 |
Intraocular invasion by microsporidial spores in a case of stromal keratitis.
Topics: Acyclovir; Adult; Biguanides; Corneal Stroma; Corneal Ulcer; Drug Therapy, Combination; Endothelium, | 2011 |
Polyhexamethylene biguanide and calcineurin inhibitors as novel antifungal treatments for Aspergillus keratitis.
Topics: Amphotericin B; Animals; Aspergillosis; Aspergillus fumigatus; Biguanides; Calcineurin Inhibitors; C | 2011 |
Diagnosis, clinical features and treatment outcome of microsporidial keratoconjunctivitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Child; Disinfectants; Eye Infections, Fungal | 2012 |
Pan-antimicrobial failure of alexidine as a contact lens disinfectant when heated in Bausch & Lomb plastic containers: implications for the worldwide Fusarium keratitis epidemic of 2004 to 2006.
Topics: Biguanides; Contact Lens Solutions; Contact Lenses; Disinfection; Drug Packaging; Drug Storage; Eye | 2012 |
Benefit of polyhexamethylene biguanide in Fusarium keratitis.
Topics: Adult; Antifungal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Corneal Ulcer; Disi | 2012 |
Microbial keratitis following vegetative matter injury.
Topics: Acanthamoeba; Adult; Amebiasis; Amikacin; Anti-Bacterial Agents; Biguanides; Corneal Ulcer; Disinfec | 2013 |
Impact of contact lens materials on multipurpose contact lens solution disinfection activity against Fusarium solani.
Topics: Biguanides; Colony Count, Microbial; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfecta | 2012 |
Role of 0.02% polyhexamethylene biguanide and 1% povidone iodine in experimental Aspergillus keratitis.
Topics: Animals; Anti-Infective Agents, Local; Aspergillosis; Aspergillus fumigatus; Biguanides; Corneal Str | 2003 |
[Acanthamoeba keratitis: about the first two Tunisian cases].
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Amebicides; Animals; Antifungal Agents; Benzamidines; B | 2007 |
Polyhexamethylene biguanide (PHMB) in the treatment of experimental Fusarium keratomycosis.
Topics: Administration, Topical; Animals; Biguanides; Colony Count, Microbial; Cornea; Disease Models, Anima | 1997 |
In-vitro activity of polyhexamethylene biguanide (PHMB) against fungal isolates associated with infective keratitis.
Topics: Biguanides; Disinfectants; Eye Infections, Fungal; Humans; Keratitis; Microbial Sensitivity Tests; M | 1999 |
Treatment of Acanthamoeba keratitis combined with fungal infection with polyhexamethylene biguanide.
Topics: Acanthamoeba Keratitis; Adult; Biguanides; Disinfectants; Eye Infections, Fungal; Fungi; Humans; Mal | 1999 |