biguanides has been researched along with Experimental Neoplasms in 5 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic treatment of female rats with buformin (k mg/day per rat) is shown to decrease the body weight, to increase the average life span by 9% and to reduce the incidence of spontaneous tumors." | 3.66 | [Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats]. ( Anisimov, VN, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anisimov, VN | 4 |
| Aleksandrov, VA | 1 |
| Belous, NM | 1 |
| Vasil'eva, IA | 1 |
| Matson, VB | 1 |
| Nishimura, T | 1 |
| Kitajima, J | 1 |
| Omura, S | 1 |
| Tanaka, N | 1 |
2 reviews available for biguanides and Experimental Neoplasms
| Article | Year |
|---|---|
[Role of the growth hormone-insulin-like growth factor-1-insulin system signaling in aging and longevity: evolutional aspect].
Topics: Aging; Animals; Biguanides; Caenorhabditis elegans; Growth Hormone; Hypoglycemic Agents; Insulin; In | 2008 |
Carcinogenesis and aging. III. The role of age in initiation and promotion of carcinogenesis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Biguanides; Carcinogens; Cell Division; Cell Transform | 1982 |
3 other studies available for biguanides and Experimental Neoplasms
| Article | Year |
|---|---|
[Inhibition of the transplacental blastomogenic effect of N-nitrosomethylurea in rats by buformin].
Topics: Animals; Antineoplastic Agents; Biguanides; Blood Glucose; Buformin; Castration; Cholesterol; Female | 1980 |
[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats].
Topics: Animals; Biguanides; Body Weight; Buformin; Estrus; Female; Longevity; Neoplasms, Experimental; Phen | 1980 |
Antitumor activity of an antibiotic identical with or closely related to xanthomycin A.
Topics: Animals; Antibiotics, Antineoplastic; Biguanides; Cell Survival; Cells, Cultured; DNA; Humans; Mice; | 1981 |