biguanides has been researched along with Dental Caries in 29 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Dental Caries: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2% chlorhexidine solution topically applied to rat teeth was effective in reducing dental plaque." | 3.66 | Antimicrobial agents and dental caries in the rat. ( McDonald, JL; Stookey, GK, 1978) |
| "The association between S." | 2.64 | Outlook for Hibitane in dental caries. ( Emilson, CG, 1977) |
| "Dental plaque is massed packed bacterial cells which accumulate on the supra- and subgingival surfaces of the teeth as well as on the oral mucosa." | 2.36 | Clinical studies of plaque control agents: an overview. ( Lobene, RR, 1979) |
| "Dental caries have become a major global public health problem." | 1.62 | Synthesis and characterization of an anti-caries and remineralizing fluorine-containing cationic polymer PHMB-F. ( Chen, F; Chen, YD; Duan, ZH; Li, XD; Li, XJ; Luo, QJ; Shu, C; Xu, JJ, 2021) |
| "Occlusar carious lesions from human molars, preserved in continuous humidity after extraction, were removed using conventional clinical techniques." | 1.26 | Effect of a Ca(OH)2 solution and a chlorhexidine based detergent on the microbial activity of human carious teeth. ( Forsten, L; Karjalainen, S, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (93.10) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YD | 1 |
| Shu, C | 1 |
| Duan, ZH | 1 |
| Xu, JJ | 1 |
| Li, XJ | 1 |
| Chen, F | 1 |
| Luo, QJ | 1 |
| Li, XD | 1 |
| Uzer Celik, E | 1 |
| Tunac, AT | 1 |
| Ates, M | 1 |
| Sen, BH | 1 |
| Lobene, RR | 1 |
| Gjermo, P | 2 |
| Shern, RJ | 2 |
| Amsbaugh, SM | 1 |
| Reynolds, R | 1 |
| Forsten, L | 1 |
| Karjalainen, S | 1 |
| Brayer, L | 1 |
| Gedalia, I | 1 |
| Gover, A | 1 |
| Kiyoshige, T | 1 |
| Yamazaki, Y | 1 |
| Futakami, K | 1 |
| McDonald, JL | 1 |
| Stookey, GK | 1 |
| Luoma, H | 1 |
| Murtomaa, H | 1 |
| Nuuja, T | 1 |
| Nyman, A | 1 |
| Nummikoski, P | 1 |
| Ainamo, J | 1 |
| Luoma, AR | 1 |
| Curtis, SN | 1 |
| Dooley, CL | 1 |
| Emilson, CG | 3 |
| Fornell, J | 1 |
| Krasse, B | 1 |
| Rölla, G | 2 |
| Spranger, H | 1 |
| Birkeland, JM | 1 |
| Johansen, JR | 1 |
| Eriksen, HM | 1 |
| Rapani, E | 1 |
| Coffin, F | 2 |
| Löe, H | 1 |
| Von der Fehr, FR | 1 |
| Schiött, CR | 1 |
| Kornman, KS | 1 |
| Clark, WB | 1 |
| Kreitzman, SN | 1 |
| Alvarez, C | 1 |
| Ochsenbein, H | 1 |
| Drízhal, I | 1 |
| Tikus, HW | 1 |
| Mühlemann, HR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ART and Hall Technique for the Management of Occlusal-proximal Caries in Primary Molars: A Randomized Clinical Trial[NCT02569047] | 131 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for biguanides and Dental Caries
| Article | Year |
|---|---|
Clinical studies of plaque control agents: an overview.
Topics: Animals; Benzoates; Biguanides; Cetylpyridinium; Chelating Agents; Cost-Benefit Analysis; Dental Car | 1979 |
[Oral hygiene in school children. Evaluation of a prophylactic program].
Topics: Adolescent; Biguanides; Child; Dental Caries; Dental Plaque; Dental Prophylaxis; Evaluation Studies | 1975 |
[Sucrose, dental plaque and caries].
Topics: Animals; Biguanides; Cariogenic Agents; Cariostatic Agents; Cricetinae; Dental Caries; Dental Plaque | 1971 |
[Chlorhexidine--a new substance for prevention of periodontal diseases and caries? (Comprehensive review)].
Topics: Animals; Anti-Infective Agents, Local; Bacteria; Biguanides; Clinical Trials as Topic; Cricetinae; D | 1974 |
4 trials available for biguanides and Dental Caries
| Article | Year |
|---|---|
Outlook for Hibitane in dental caries.
Topics: Administration, Topical; Animals; Biguanides; Chlorhexidine; Clinical Trials as Topic; Cricetinae; D | 1977 |
Effect of toothbrushing with chlorhexidine gel on salivary microflora, oral hygiene, and caries.
Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Caries; Dental Plaque; Drug Evalu | 1976 |
Effect of 2-years' use of chlorhexidine-containing dentifrices on plaque, gingivitis, and caries.
Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Caries; Dental Plaque; Dentifrice | 1975 |
[Chlorhexidine--a new substance for prevention of periodontal diseases and caries? (Comprehensive review)].
Topics: Animals; Anti-Infective Agents, Local; Bacteria; Biguanides; Clinical Trials as Topic; Cricetinae; D | 1974 |
22 other studies available for biguanides and Dental Caries
| Article | Year |
|---|---|
Synthesis and characterization of an anti-caries and remineralizing fluorine-containing cationic polymer PHMB-F.
Topics: Biguanides; Cariostatic Agents; Dental Caries; Fluorides; Fluorine; Humans; Polymers; Tooth Reminera | 2021 |
Antimicrobial activity of different disinfectants against cariogenic microorganisms.
Topics: Agar; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Dental Caries; | 2016 |
Some aspects of drug dynamics as related to oral soft tissue.
Topics: Absorption; Adsorption; Animals; Bacteria; Biguanides; Chlorhexidine; Dental Caries; Dental Plaque; | 1975 |
Effects of daily rinses using sodium fluoride and organic fluorides on rat caries.
Topics: Amines; Animals; Biguanides; Chlorides; Dental Caries; Drug Evaluation; Female; Fluorides; Mouthwash | 1977 |
Effect of a Ca(OH)2 solution and a chlorhexidine based detergent on the microbial activity of human carious teeth.
Topics: Aminopeptidases; Bacteria; Biguanides; Calcium Hydroxide; Chlorhexidine; Dental Caries; Dentin; Dete | 1977 |
Chlorhexide and fluoride in prevention of plaque and caries in hamsters.
Topics: Animals; Biguanides; Chlorhexidine; Cricetinae; Dental Caries; Dental Plaque; Diet, Cariogenic; Drug | 1977 |
[Effects of chlorhexidine and monofluorophosphate combinations on the reduction of dental caries and plaque accumulation in rats].
Topics: Animals; Biguanides; Chlorhexidine; Dental Caries; Dental Plaque; Drug Synergism; Fluorides; Rats | 1977 |
Antimicrobial agents and dental caries in the rat.
Topics: Animals; Biguanides; Cetylpyridinium; Chlorhexidine; Dental Caries; Dental Plaque; Female; Pyridiniu | 1978 |
A simultaneous reduction of caries and gingivitis in a group of schoolchildren receiving chlorhexidine-fluoride applications. Results after 2 years.
Topics: Adolescent; Biguanides; Child; Chlorhexidine; Dental Caries; DMF Index; Drug Combinations; Drug Syne | 1978 |
Cariostatic activity of (1,6-bis-[2-ethylhexylbiguanido]-hexane) in conventional rats.
Topics: Animals; Biguanides; Cariostatic Agents; Chlorhexidine; Chlorides; Dental Caries; Diet, Cariogenic; | 1979 |
The effect of some bis-biguanides on experimental dental caries in the hamster.
Topics: Animals; Biguanides; Chlorhexidine; Cricetinae; Dental Caries; Dental Plaque; Feces; Streptococcus m | 1976 |
[Indications and application possibilities of a chlorhexidine in dentistry. Review of the literature].
Topics: Biguanides; Chlorhexidine; Dental Caries; Disinfectants; Humans | 1976 |
Effects of various organic compounds and fluoride on dental plaque and caries in rats.
Topics: Actinomyces; Animals; Biguanides; Cariostatic Agents; Cations; Dental Caries; Dental Plaque; Female; | 1988 |
[Mouthrinses in the prevention of dental caries].
Topics: Biguanides; Chlorhexidine; Dental Caries; Dental Plaque; Humans; Mouthwashes | 1985 |
European Organization for Caries Research. Abstracts of papers read. 20th Congress-Zurich, July 20 to 22, 1973.
Topics: Animals; Biguanides; Bone Resorption; Cariostatic Agents; Chemistry; Congresses as Topic; Dental Car | 1973 |
The control of radiation caries.
Topics: Acrylic Resins; Biguanides; Child; Dental Caries; Dentifrices; Humans; Hyperbaric Oxygenation; Radio | 1973 |
The management of radiation caries.
Topics: Acrylic Resins; Anti-Infective Agents, Local; Biguanides; Child; Dental Caries; Humans; Mouth Neopla | 1973 |
Inhibition of experimental caries by plaque prevention. The effect of chlorhexidine mouthrinses.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Dental Caries; Dental Caries Activity Tests; Dental | 1972 |
Caries control in the albino rat with chlorhexidine gluconate (Hibitane).
Topics: Alopecia; Animals; Biguanides; Body Weight; Dental Caries; Dental Enamel; Drinking Behavior; Rats; W | 1973 |
[Chlorhexidine in dentistry--current status of research (3)].
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorobenzenes; Dental Caries; Dental Plaque; Den | 1974 |
Topical gels containing Chlorhexidine, Vantocil, Fluorophene and animal caries.
Topics: Animals; Anti-Infective Agents, Local; Antifungal Agents; Biguanides; Dental Caries; Gels; Rats | 1973 |
Chlorhexidine, Vantocil, Fluorophene and antimycotic agents in an animal caries test.
Topics: Animals; Anti-Infective Agents, Local; Antifungal Agents; Antitubercular Agents; Biguanides; Dental | 1973 |