Compounds > biguanides
Page last updated: 2024-11-08

biguanides and Cross Infection

biguanides has been researched along with Cross Infection in 25 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Cross Infection: Any infection which a patient contracts in a health-care institution.

Research Excerpts

ExcerptRelevanceReference
"The exposure of human osteoblasts and endothelial cells to polyhexanide at concentrations with questionable antibacterial activity resulted in severe cell damage whereas exposure to high dosed gentamicin did not."1.34Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells. ( Eulert, J; Hendrich, C; Ince, A; Jakob, F; Löhr, JF; Schütze, N, 2007)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199014 (56.00)18.7374
1990's0 (0.00)18.2507
2000's4 (16.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Zheng, Y1
Wang, D1
Ma, LZ1
Ali, S1
Wilson, APR1
Dittmann, K1
Schmidt, T1
Müller, G1
Cuny, C1
Holtfreter, S1
Troitzsch, D1
Pfaff, P1
Hübner, NO1
Back, DA1
Scheuermann-Poley, C1
Willy, C1
Kahar Bador, M1
Rai, V1
Yusof, MY1
Kwong, WK1
Assadian, O1
López-Rojas, R1
Fernández-Cuenca, F1
Serrano-Rocha, L1
Pascual, Á1
Mueller, SW1
Krebsbach, LE1
Williams, GJ1
Denyer, SP1
Hosein, IK1
Hill, DW1
Maillard, JY1
Oulé, MK1
Quinn, K1
Dickman, M1
Bernier, AM1
Rondeau, S1
De Moissac, D1
Boisvert, A1
Diop, L1
Salas Campos, L1
Gómez Ferrero, O1
Estudillo Pérez, V1
Fernández Mansilla, M1
Ince, A1
Schütze, N1
Hendrich, C1
Jakob, F1
Eulert, J1
Löhr, JF1
Wishart, MM1
Riley, TV1
Roszkowski, I1
Leibschang, J1
Kurtz, JB1
Boxall, J1
Speller, DC1
Stephens, ME1
Viant, AC1
O'Flynn, JD1
Stickler, DJ1
Myers, JA1
MacDonald, K1
Dowsett, EG1
Phillips, I1
King, A1
Jenkins, S1
Spencer, G1
Bassett, DC1
Stokes, KJ1
Thomas, WR1
Palmer, PH1
Yeoman, DM1
Lowbury, EJ1
Hennes, HH1
Kienholz, M1
Küffer, R1
Badillet, G1
Cathala, F1
Rouchon, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Micro/Nanobubbles (MNBs) and Wound Therapy: A Pilot Study Involving a Novel Oxygen Delivery System for Treatment of Acute and Chronic Wounds[NCT05169814]Early Phase 140 participants (Anticipated)Interventional2021-10-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for biguanides and Cross Infection

ArticleYear
Recommendations on negative pressure wound therapy with instillation and antimicrobial solutions - when, where and how to use: what does the evidence show?
    International wound journal, 2013, Volume: 10 Suppl 1

    Topics: Acetic Acid; Anti-Infective Agents, Local; Biguanides; Cross Infection; Evidence-Based Medicine; Hum

2013

Other Studies

24 other studies available for biguanides and Cross Infection

ArticleYear
Effect of Polyhexamethylene Biguanide in Combination with Undecylenamidopropyl Betaine or PslG on Biofilm Clearance.
    International journal of molecular sciences, 2021, Jan-14, Volume: 22, Issue:2

    Topics: Bacteria; Bacterial Infections; Betaine; Biguanides; Biofilms; Candida albicans; Candidiasis; Cross

2021
Effect of poly-hexamethylene biguanide hydrochloride (PHMB) treated non-sterile medical gloves upon the transmission of Streptococcus pyogenes, carbapenem-resistant E. coli, MRSA and Klebsiella pneumoniae from contact surfaces.
    BMC infectious diseases, 2017, 08-17, Volume: 17, Issue:1

    Topics: Biguanides; Carbapenems; Cross Infection; Disease Transmission, Infectious; Disinfectants; Drug Resi

2017
Susceptibility of livestock-associated methicillin-resistant
    Antimicrobial resistance and infection control, 2019, Volume: 8

    Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Community-Acquired Infections; Cro

2019
Evaluation of the efficacy of antibacterial medical gloves in the ICU setting.
    The Journal of hospital infection, 2015, Volume: 90, Issue:3

    Topics: Anti-Bacterial Agents; Biguanides; Colony Count, Microbial; Cross Infection; Gloves, Protective; Glo

2015
In vitro activity of a polyhexanide-betaine solution against high-risk clones of multidrug-resistant nosocomial pathogens.
    Enfermedades infecciosas y microbiologia clinica, 2017, Volume: 35, Issue:1

    Topics: Bacteria; Betaine; Biguanides; Cross Infection; Disinfectants; Microbial Sensitivity Tests; Solution

2017
Impact of an antimicrobial-impregnated gauze dressing on surgical site infections including methicillin-resistant Staphylococcus aureus infections.
    American journal of infection control, 2008, Volume: 36, Issue:9

    Topics: Bandages; Biguanides; Cross Infection; Disinfectants; Humans; Length of Stay; Methicillin-Resistant

2008
Limitations of the efficacy of surface disinfection in the healthcare setting.
    Infection control and hospital epidemiology, 2009, Volume: 30, Issue:6

    Topics: Anti-Bacterial Agents; Biguanides; Cross Infection; Disinfectants; Disinfection; Equipment Contamina

2009
Akwaton, polyhexamethylene-guanidine hydrochloride-based sporicidal disinfectant: a novel tool to fight bacterial spores and nosocomial infections.
    Journal of medical microbiology, 2012, Volume: 61, Issue:Pt 10

    Topics: Bacillus subtilis; Bacterial Infections; Bacteriological Techniques; Biguanides; Cross Infection; Di

2012
[Preventing nosocomial infections. Dressings soaked in polyhexamethylene biguanide (PHMB)].
    Revista de enfermeria (Barcelona, Spain), 2006, Volume: 29, Issue:6

    Topics: Anti-Bacterial Agents; Bandages; Biguanides; Cross Infection; Humans; Surgical Wound Infection

2006
Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells.
    Swiss medical weekly, 2007, Mar-10, Volume: 137, Issue:9-10

    Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement

2007
Methods of prevention and control of nosocomial infections.
    National Nosocomial Infections Study report, 1977

    Topics: Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Cross Infection; Humans; Skin

1977
Infection with Pseudomonas maltophilia hospital outbreak due to contaminated disinfectant.
    The Medical journal of Australia, 1976, Nov-06, Volume: 2, Issue:19

    Topics: Adult; Aged; Australia; Biguanides; Cetrimonium Compounds; Chlorhexidine; Cross Infection; Disease O

1976
[Clinical and laboratory evaluation of Hibiscrub].
    Ginekologia polska, 1975, Volume: 46, Issue:5

    Topics: Biguanides; Chlorhexidine; Cross Infection; Disinfectants; Female; Humans; Personnel, Hospital; Preg

1975
Cross-infection: a partial substitute for hand washing.
    Nursing times, 1976, Mar-04, Volume: 72, Issue:9

    Topics: Antisepsis; Biguanides; Chlorhexidine; Costs and Cost Analysis; Cross Infection; England; Hand; Huma

1976
Hospital infection by Pseudomonas cepacia.
    Lancet (London, England), 1971, Apr-17, Volume: 1, Issue:7703

    Topics: Anti-Infective Agents, Local; Biguanides; Cross Infection; Disease Outbreaks; Humans; Pseudomonas; P

1971
Disinfectants and gram-negative bacteria.
    Lancet (London, England), 1972, Feb-26, Volume: 1, Issue:7748

    Topics: Biguanides; Cross Infection; Culture Media; Disinfectants; Enterobacteriaceae; Enterobacteriaceae In

1972
Hospital infections caused by contaminated fluids.
    Lancet (London, England), 1972, Aug-05, Volume: 2, Issue:7771

    Topics: Acetates; Anti-Infective Agents; Biguanides; Cross Infection; Humans; Infusions, Parenteral; Sterili

1972
Hospital infections caused by contaminated fluids.
    Lancet (London, England), 1972, Sep-16, Volume: 2, Issue:7777

    Topics: Biguanides; Central Supply, Hospital; Cross Infection; Disinfectants; Drug Packaging; Drug Stability

1972
Control of respirator-associated infection due to Pseudomonas aeruginosa.
    Lancet (London, England), 1974, Oct-12, Volume: 2, Issue:7885

    Topics: Aerosols; Alcohols; Biguanides; Chlorobenzenes; Cross Infection; Disinfection; Evaluation Studies as

1974
Wound infection with Pseudomonas multivorans. A water-borne contaminant of disinfectant solutions.
    Lancet (London, England), 1970, Jun-06, Volume: 1, Issue:7658

    Topics: Adolescent; Adult; Aged; Biguanides; Cross Infection; Disinfectants; Drug Resistance, Microbial; Fem

1970
A study to assess the value of disinfectants when washing ward floors.
    The Medical journal of Australia, 1972, Nov-25, Volume: 2, Issue:22

    Topics: Agar; Air Microbiology; Bacteria; Bacteriological Techniques; Biguanides; Cross Infection; Disinfect

1972
Gram-negative bacilli on the skin.
    The British journal of dermatology, 1969, Volume: 81

    Topics: Bacteria; Biguanides; Burns; Child; Cross Infection; Escherichia coli; Humans; Proteus; Pseudomonas

1969
[The disinfection of anesthesia equipment with chlorohexidine].
    Der Anaesthesist, 1970, Volume: 19, Issue:3

    Topics: Anesthesiology; Biguanides; Cross Infection; Disinfectants; Gluconates; Humans; Methods; Microbial S

1970
[2 cases of herpetic primo-infection in young women. Contamination by buccal contact].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:4

    Topics: Adult; Biguanides; Cross Infection; Humans

1970