biguanides has been researched along with Cell Transformation, Neoplastic in 3 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of cancer increases with age in humans and in laboratory animals alike." | 2.45 | Relationships between cancer and aging: a multilevel approach. ( Anisimov, VN; Pawelec, G; Sikora, E, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anisimov, VN | 3 |
| Sikora, E | 1 |
| Pawelec, G | 1 |
3 reviews available for biguanides and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Relationships between cancer and aging: a multilevel approach.
Topics: Age Distribution; Age Factors; Aging; Animals; Anticarcinogenic Agents; Biguanides; Carcinogens; Cel | 2009 |
Insulin/IGF-1 signaling pathway driving aging and cancer as a target for pharmacological intervention.
Topics: Aging; Animals; Biguanides; Cell Transformation, Neoplastic; Humans; Insulin; Insulin-Like Growth Fa | 2003 |
Carcinogenesis and aging. III. The role of age in initiation and promotion of carcinogenesis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Biguanides; Carcinogens; Cell Division; Cell Transform | 1982 |