Page last updated: 2024-11-08

biguanides and Caries, Dental

biguanides has been researched along with Caries, Dental in 29 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Research Excerpts

ExcerptRelevanceReference
"2% chlorhexidine solution topically applied to rat teeth was effective in reducing dental plaque."3.66Antimicrobial agents and dental caries in the rat. ( McDonald, JL; Stookey, GK, 1978)
"The association between S."2.64Outlook for Hibitane in dental caries. ( Emilson, CG, 1977)
"Dental plaque is massed packed bacterial cells which accumulate on the supra- and subgingival surfaces of the teeth as well as on the oral mucosa."2.36Clinical studies of plaque control agents: an overview. ( Lobene, RR, 1979)
"Dental caries have become a major global public health problem."1.62Synthesis and characterization of an anti-caries and remineralizing fluorine-containing cationic polymer PHMB-F. ( Chen, F; Chen, YD; Duan, ZH; Li, XD; Li, XJ; Luo, QJ; Shu, C; Xu, JJ, 2021)
"Occlusar carious lesions from human molars, preserved in continuous humidity after extraction, were removed using conventional clinical techniques."1.26Effect of a Ca(OH)2 solution and a chlorhexidine based detergent on the microbial activity of human carious teeth. ( Forsten, L; Karjalainen, S, 1977)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199027 (93.10)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (3.45)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Chen, YD1
Shu, C1
Duan, ZH1
Xu, JJ1
Li, XJ1
Chen, F1
Luo, QJ1
Li, XD1
Uzer Celik, E1
Tunac, AT1
Ates, M1
Sen, BH1
Lobene, RR1
Gjermo, P2
Shern, RJ2
Amsbaugh, SM1
Reynolds, R1
Forsten, L1
Karjalainen, S1
Brayer, L1
Gedalia, I1
Gover, A1
Kiyoshige, T1
Yamazaki, Y1
Futakami, K1
McDonald, JL1
Stookey, GK1
Luoma, H1
Murtomaa, H1
Nuuja, T1
Nyman, A1
Nummikoski, P1
Ainamo, J1
Luoma, AR1
Curtis, SN1
Dooley, CL1
Emilson, CG3
Fornell, J1
Krasse, B1
Rölla, G2
Spranger, H1
Birkeland, JM1
Johansen, JR1
Eriksen, HM1
Rapani, E1
Coffin, F2
Löe, H1
Von der Fehr, FR1
Schiött, CR1
Kornman, KS1
Clark, WB1
Kreitzman, SN1
Alvarez, C1
Ochsenbein, H1
Drízhal, I1
Tikus, HW1
Mühlemann, HR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ART and Hall Technique for the Management of Occlusal-proximal Caries in Primary Molars: A Randomized Clinical Trial[NCT02569047]131 participants (Actual)Interventional2015-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for biguanides and Caries, Dental

ArticleYear
Clinical studies of plaque control agents: an overview.
    Journal of dental research, 1979, Volume: 58, Issue:12

    Topics: Animals; Benzoates; Biguanides; Cetylpyridinium; Chelating Agents; Cost-Benefit Analysis; Dental Car

1979
[Oral hygiene in school children. Evaluation of a prophylactic program].
    Den Norske tannlaegeforenings tidende, 1975, Volume: 85, Issue:3

    Topics: Adolescent; Biguanides; Child; Dental Caries; Dental Plaque; Dental Prophylaxis; Evaluation Studies

1975
[Sucrose, dental plaque and caries].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, Apr-10, Volume: 91, Issue:10

    Topics: Animals; Biguanides; Cariogenic Agents; Cariostatic Agents; Cricetinae; Dental Caries; Dental Plaque

1971
[Chlorhexidine--a new substance for prevention of periodontal diseases and caries? (Comprehensive review)].
    Ceskoslovenska stomatologie, 1974, Volume: 74, Issue:5

    Topics: Animals; Anti-Infective Agents, Local; Bacteria; Biguanides; Clinical Trials as Topic; Cricetinae; D

1974

Trials

4 trials available for biguanides and Caries, Dental

ArticleYear
Outlook for Hibitane in dental caries.
    Journal of clinical periodontology, 1977, Volume: 4, Issue:5

    Topics: Administration, Topical; Animals; Biguanides; Chlorhexidine; Clinical Trials as Topic; Cricetinae; D

1977
Effect of toothbrushing with chlorhexidine gel on salivary microflora, oral hygiene, and caries.
    Scandinavian journal of dental research, 1976, Volume: 84, Issue:5

    Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Caries; Dental Plaque; Drug Evalu

1976
Effect of 2-years' use of chlorhexidine-containing dentifrices on plaque, gingivitis, and caries.
    Scandinavian journal of dental research, 1975, Volume: 83, Issue:5

    Topics: Adult; Biguanides; Chlorhexidine; Clinical Trials as Topic; Dental Caries; Dental Plaque; Dentifrice

1975
[Chlorhexidine--a new substance for prevention of periodontal diseases and caries? (Comprehensive review)].
    Ceskoslovenska stomatologie, 1974, Volume: 74, Issue:5

    Topics: Animals; Anti-Infective Agents, Local; Bacteria; Biguanides; Clinical Trials as Topic; Cricetinae; D

1974

Other Studies

22 other studies available for biguanides and Caries, Dental

ArticleYear
Synthesis and characterization of an anti-caries and remineralizing fluorine-containing cationic polymer PHMB-F.
    Biomaterials science, 2021, Mar-21, Volume: 9, Issue:6

    Topics: Biguanides; Cariostatic Agents; Dental Caries; Fluorides; Fluorine; Humans; Polymers; Tooth Reminera

2021
Antimicrobial activity of different disinfectants against cariogenic microorganisms.
    Brazilian oral research, 2016, Nov-28, Volume: 30, Issue:1

    Topics: Agar; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Dental Caries;

2016
Some aspects of drug dynamics as related to oral soft tissue.
    Journal of dental research, 1975, Volume: 54 Spec No B

    Topics: Absorption; Adsorption; Animals; Bacteria; Biguanides; Chlorhexidine; Dental Caries; Dental Plaque;

1975
Effects of daily rinses using sodium fluoride and organic fluorides on rat caries.
    Journal of dental research, 1977, Volume: 56, Issue:9

    Topics: Amines; Animals; Biguanides; Chlorides; Dental Caries; Drug Evaluation; Female; Fluorides; Mouthwash

1977
Effect of a Ca(OH)2 solution and a chlorhexidine based detergent on the microbial activity of human carious teeth.
    Acta odontologica Scandinavica, 1977, Volume: 35, Issue:6

    Topics: Aminopeptidases; Bacteria; Biguanides; Calcium Hydroxide; Chlorhexidine; Dental Caries; Dentin; Dete

1977
Chlorhexide and fluoride in prevention of plaque and caries in hamsters.
    Journal of dental research, 1977, Volume: 56, Issue:11

    Topics: Animals; Biguanides; Chlorhexidine; Cricetinae; Dental Caries; Dental Plaque; Diet, Cariogenic; Drug

1977
[Effects of chlorhexidine and monofluorophosphate combinations on the reduction of dental caries and plaque accumulation in rats].
    Koku Eisei Gakkai zasshi, 1977, Volume: 27, Issue:3

    Topics: Animals; Biguanides; Chlorhexidine; Dental Caries; Dental Plaque; Drug Synergism; Fluorides; Rats

1977
Antimicrobial agents and dental caries in the rat.
    Journal of dental research, 1978, Volume: 57, Issue:2

    Topics: Animals; Biguanides; Cetylpyridinium; Chlorhexidine; Dental Caries; Dental Plaque; Female; Pyridiniu

1978
A simultaneous reduction of caries and gingivitis in a group of schoolchildren receiving chlorhexidine-fluoride applications. Results after 2 years.
    Caries research, 1978, Volume: 12, Issue:5

    Topics: Adolescent; Biguanides; Child; Chlorhexidine; Dental Caries; DMF Index; Drug Combinations; Drug Syne

1978
Cariostatic activity of (1,6-bis-[2-ethylhexylbiguanido]-hexane) in conventional rats.
    Journal of dental research, 1979, Volume: 58, Issue:4

    Topics: Animals; Biguanides; Cariostatic Agents; Chlorhexidine; Chlorides; Dental Caries; Diet, Cariogenic;

1979
The effect of some bis-biguanides on experimental dental caries in the hamster.
    Caries research, 1976, Volume: 10, Issue:5

    Topics: Animals; Biguanides; Chlorhexidine; Cricetinae; Dental Caries; Dental Plaque; Feces; Streptococcus m

1976
[Indications and application possibilities of a chlorhexidine in dentistry. Review of the literature].
    Zahnarztliche Praxis, 1976, May-07, Volume: 27, Issue:9

    Topics: Biguanides; Chlorhexidine; Dental Caries; Disinfectants; Humans

1976
Effects of various organic compounds and fluoride on dental plaque and caries in rats.
    Caries research, 1988, Volume: 22, Issue:3

    Topics: Actinomyces; Animals; Biguanides; Cariostatic Agents; Cations; Dental Caries; Dental Plaque; Female;

1988
[Mouthrinses in the prevention of dental caries].
    Rivista di odontostomatologia e implantoprotesi, 1985, Issue:2

    Topics: Biguanides; Chlorhexidine; Dental Caries; Dental Plaque; Humans; Mouthwashes

1985
European Organization for Caries Research. Abstracts of papers read. 20th Congress-Zurich, July 20 to 22, 1973.
    Helvetica odontologica acta, 1973, Volume: 17, Issue:2

    Topics: Animals; Biguanides; Bone Resorption; Cariostatic Agents; Chemistry; Congresses as Topic; Dental Car

1973
The control of radiation caries.
    The British journal of radiology, 1973, Volume: 46, Issue:545

    Topics: Acrylic Resins; Biguanides; Child; Dental Caries; Dentifrices; Humans; Hyperbaric Oxygenation; Radio

1973
The management of radiation caries.
    The British journal of oral surgery, 1973, Volume: 11, Issue:1

    Topics: Acrylic Resins; Anti-Infective Agents, Local; Biguanides; Child; Dental Caries; Humans; Mouth Neopla

1973
Inhibition of experimental caries by plaque prevention. The effect of chlorhexidine mouthrinses.
    Scandinavian journal of dental research, 1972, Volume: 80, Issue:1

    Topics: Adult; Anti-Infective Agents, Local; Biguanides; Dental Caries; Dental Caries Activity Tests; Dental

1972
Caries control in the albino rat with chlorhexidine gluconate (Hibitane).
    Archives of oral biology, 1973, Volume: 18, Issue:2

    Topics: Alopecia; Animals; Biguanides; Body Weight; Dental Caries; Dental Enamel; Drinking Behavior; Rats; W

1973
[Chlorhexidine in dentistry--current status of research (3)].
    Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1974, Volume: 84, Issue:4

    Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorobenzenes; Dental Caries; Dental Plaque; Den

1974
Topical gels containing Chlorhexidine, Vantocil, Fluorophene and animal caries.
    Helvetica odontologica acta, 1973, Volume: 17, Issue:2

    Topics: Animals; Anti-Infective Agents, Local; Antifungal Agents; Biguanides; Dental Caries; Gels; Rats

1973
Chlorhexidine, Vantocil, Fluorophene and antimycotic agents in an animal caries test.
    Helvetica odontologica acta, 1973, Volume: 17, Issue:2

    Topics: Animals; Anti-Infective Agents, Local; Antifungal Agents; Antitubercular Agents; Biguanides; Dental

1973