biguanides has been researched along with Burns in 19 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Between January 2006, and September 2007, 28 patients with acute traumatic wounds and burns requiring skin grafting were randomly assigned in a 1:1 fashion to receive standard topical therapy (nonadherent silicone mesh [Mepitel, Mölnlycke Health Care] and antiseptic gel [polyhexanide/octenidine]) to graft donor sites with (n = 13) or without (n = 15) defocused extracorporeal shock wave therapy (ESWT, 100 impulses/cm(2) at 0." | 5.14 | Prospective randomized trial of accelerated re-epithelization of skin graft donor sites using extracorporeal shock wave therapy. ( Hartmann, B; Maier, H; Ottomann, C; Schaden, W; Stojadinovic, A; Thiele, R; Tyler, J, 2010) |
| "2% chlorhexidine digluconate (SNC) showed that all were comparably effective in protecting burns from infection." | 5.04 | Topical chemoprophylaxis with silver sulphadiazine and silver nitrate chlorhexidine creams: emergence of sulphonamide-resistant Gram-negative bacilli. ( Babb, JR; Bridges, K; Jackson, DM; Lowbury, EJ, 1976) |
| "The majority of children treated for burns (80." | 1.48 | A retrospective systematic data review on the use of a polihexanide-containing product on burns in children. ( Budkevich, L; Ciprandi, G; Marathovouniotis, N; Ramsay, S; Strack, A; van Capellen, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wattanaploy, S | 1 |
| Chinaroonchai, K | 1 |
| Namviriyachote, N | 1 |
| Muangman, P | 1 |
| Kiefer, J | 1 |
| Harati, K | 1 |
| Müller-Seubert, W | 1 |
| Fischer, S | 1 |
| Ziegler, B | 1 |
| Behr, B | 1 |
| Gille, J | 1 |
| Kneser, U | 1 |
| Lehnhardt, M | 1 |
| Daigeler, A | 1 |
| Dragu, A | 1 |
| Schulz, A | 1 |
| Fuchs, PC | 1 |
| Hans, N | 1 |
| Opländer, C | 1 |
| Valdez, LB | 1 |
| Schiefer, JL | 1 |
| Ciprandi, G | 1 |
| Ramsay, S | 1 |
| Budkevich, L | 1 |
| Strack, A | 1 |
| van Capellen, P | 1 |
| Marathovouniotis, N | 1 |
| Krezdorn, N | 1 |
| Könneker, S | 1 |
| Paprottka, FJ | 1 |
| Tapking, C | 1 |
| Mett, TR | 1 |
| Brölsch, GF | 1 |
| Boyce, M | 1 |
| Ipaktchi, R | 1 |
| Vogt, PM | 1 |
| Ottomann, C | 2 |
| Hartmann, B | 2 |
| Tyler, J | 1 |
| Maier, H | 1 |
| Thiele, R | 2 |
| Schaden, W | 2 |
| Stojadinovic, A | 2 |
| Piatkowski, A | 1 |
| Drummer, N | 1 |
| Andriessen, A | 1 |
| Ulrich, D | 1 |
| Pallua, N | 1 |
| Lavin, PT | 1 |
| Gannon, FH | 1 |
| Heggeness, MH | 1 |
| Daeschlein, G | 1 |
| Assadian, O | 1 |
| Bruck, JC | 1 |
| Meinl, C | 1 |
| Kramer, A | 1 |
| Koch, S | 1 |
| Lawrence, JC | 2 |
| Clarke, AM | 3 |
| Lowbury, EJ | 2 |
| Babb, JR | 1 |
| Bridges, K | 1 |
| Jackson, DM | 1 |
| Pannier, M | 1 |
| Lebeaupin, R | 1 |
| Guimbretière, J | 1 |
| Billaudel, S | 1 |
| Courtieu, AL | 1 |
| Solomon, J | 2 |
| Keogh, J | 2 |
| Nixon, M | 2 |
| Burchett, J | 2 |
| Muir, IF | 1 |
| Owen, D | 1 |
| Murphy, J | 1 |
| Lilly, HA | 1 |
| Grant, JC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial Comparing Suprathel Versus Xeroform for the Management of Pediatric and Adult Split Thickness Skin Graft Donor Sites[NCT04014400] | 10 participants (Actual) | Interventional | 2019-07-07 | Terminated (stopped due to We observed that using the Suprathel dressing required additional treatment of the wound and had a longer healing time than the standard of care Xeroform dressing; it did not dry the wound out properly to promote healing.) | |||
| Accelerated Healing of Second Degree Burns and the Effect of Musculoskeletal Shockwave Therapy on the Recovery of Skin Graft Donor Sites[NCT01242423] | Phase 2/Phase 3 | 100 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for biguanides and Burns
| Article | Year |
|---|---|
Randomized Controlled Trial of Polyhexanide/Betaine Gel Versus Silver Sulfadiazine for Partial-Thickness Burn Treatment.
Topics: Adult; Anti-Infective Agents, Local; Bandages, Hydrocolloid; Betaine; Biguanides; Burns; Drug Combin | 2017 |
Efficacy of a Gel Containing Polihexanide and Betaine in Deep Partial and Full Thickness Burns Requiring Split-thickness Skin Grafts: A Noncomparative Clinical Study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Betaine; Biguanides; Burns; Disinfectants; | 2018 |
Prospective randomized trial of accelerated re-epithelization of skin graft donor sites using extracorporeal shock wave therapy.
Topics: Adult; Aged; Anti-Infective Agents, Local; Biguanides; Burns; Epithelium; Female; Humans; Imines; Li | 2010 |
Randomized controlled single center study comparing a polyhexanide containing bio-cellulose dressing with silver sulfadiazine cream in partial-thickness dermal burns.
Topics: Adult; Anti-Infective Agents, Local; Bandages; Biguanides; Biocompatible Materials; Burns; Cellulose | 2011 |
Prospective randomized phase II Trial of accelerated reepithelialization of superficial second-degree burn wounds using extracorporeal shock wave therapy.
Topics: Adult; Aged; Anti-Infective Agents, Local; Biguanides; Burns; Cohort Studies; Debridement; Female; G | 2012 |
Feasibility and clinical applicability of polihexanide for treatment of second-degree burn wounds.
Topics: Adolescent; Adult; Anti-Infective Agents, Local; Biguanides; Burns; Epithelium; Female; Humans; Male | 2007 |
Topical chemoprophylaxis with silver sulphadiazine and silver nitrate chlorhexidine creams: emergence of sulphonamide-resistant Gram-negative bacilli.
Topics: Administration, Topical; Adolescent; Adult; Bacteria; Biguanides; Burns; Child; Child, Preschool; Ch | 1976 |
Sulfamylon acetate in the treatment of pseudomonas pyocyanea infection of burns.
Topics: Adolescent; Adult; Aged; Bandages; Biguanides; Burns; Child; Clinical Trials as Topic; Female; Human | 1969 |
11 other studies available for biguanides and Burns
| Article | Year |
|---|---|
Inhibition of Bromelain Activity During Enzymatic Debridement of Burn Wounds Pretreated With Frequently Used Products.
Topics: Anti-Infective Agents, Local; Betaine; Biguanides; Bromelains; Burns; Collagen; Debridement; Elastin | 2018 |
A retrospective systematic data review on the use of a polihexanide-containing product on burns in children.
Topics: Adolescent; Bandages; Biguanides; Burns; Child; Child, Preschool; Disinfectants; Female; Humans; Inf | 2018 |
Biobrane versus topical agents in the treatment of adult scald burns.
Topics: Administration, Cutaneous; Adult; Age Factors; Aged; Alcohol Drinking; Biguanides; Body Surface Area | 2017 |
Minor burns.
Topics: Bandages; Biguanides; Burns; Chlorhexidine; Humans; Wound Healing; Wound Infection | 1977 |
Topical use of silver sulphadiazine and chlorhexidine in the prevention of infection in thermal injuries.
Topics: Administration, Topical; Anti-Infective Agents, Local; Bacteria; Biguanides; Burns; Child; Chlorhexi | 1975 |
[Use of chlorhexidine in balneotherapy of severe burn patients].
Topics: Baths; Biguanides; Burns; Chlorhexidine; Humans | 1976 |
Topical treatment of burns.
Topics: Anti-Infective Agents, Local; Biguanides; Burns; Drug Synergism; Evaluation Studies as Topic; Humans | 1971 |
A quantitative method for investigating the bacteriology of skin: its application to burns.
Topics: Animals; Bacteriological Techniques; Biguanides; Biopsy; Burns; Cell Count; Cold Temperature; Disinf | 1972 |
Antiseptics in treatment of burns.
Topics: Anti-Infective Agents, Local; Benzoates; Biguanides; Burns; Child, Preschool; Humans; Infection Cont | 1968 |
Gram-negative bacilli on the skin.
Topics: Bacteria; Biguanides; Burns; Child; Cross Infection; Escherichia coli; Humans; Proteus; Pseudomonas | 1969 |
Chlorhexidine with silver-sulphadiazine in the treatment of burns.
Topics: Anti-Infective Agents, Local; Biguanides; Burns; Drug Synergism; Humans; Silver; Sulfadiazine | 1971 |