biguanides has been researched along with Brain Ischemia in 2 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Platelet thrombosis is the main pathogeny resulting in the low curability of ischemic stroke, a leading cause of mortality and disability worldwide." | 1.56 | Novel potent antiplatelet thrombotic agent derived from biguanide for ischemic stroke. ( Chen, Z; He, Y; Huang, W; Ji, C; Lee, KH; Li, S; Li, Y; Ming, Y; Morris-Natschke, SL; Niu, H; Wei, Z; Xin, G; Xing, Z; Yang, X; Yu, K; Zhang, B; Zhang, J; Zhang, X, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xin, G | 1 |
| Ming, Y | 1 |
| Ji, C | 1 |
| Wei, Z | 1 |
| Li, S | 1 |
| Morris-Natschke, SL | 1 |
| Zhang, X | 1 |
| Yu, K | 1 |
| Li, Y | 1 |
| Zhang, B | 1 |
| Zhang, J | 1 |
| Xing, Z | 1 |
| He, Y | 1 |
| Chen, Z | 1 |
| Yang, X | 1 |
| Niu, H | 1 |
| Lee, KH | 1 |
| Huang, W | 1 |
| Safonova, OA | 1 |
| Popova, TN | 1 |
| Panchenko, LF | 1 |
2 other studies available for biguanides and Brain Ischemia
| Article | Year |
|---|---|
Novel potent antiplatelet thrombotic agent derived from biguanide for ischemic stroke.
Topics: Administration, Oral; Animals; Biguanides; Brain Ischemia; Dose-Response Relationship, Drug; Male; M | 2020 |
Effects of 2,4-dimethoxyphenyl biguanide on glutathione system activity in rat tissues in brain ischemia-reperfusion.
Topics: Animals; Antioxidants; Biguanides; Brain; Brain Ischemia; Glucosephosphate Dehydrogenase; Glutathion | 2011 |