biguanides has been researched along with Brain Edema in 1 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stroke was rendered in rats by introduction of an autologous clot into the middle cerebral artery (MCA)." | 5.37 | Tropisetron ameliorates ischemic brain injury in an embolic model of stroke. ( Barzegar-Fallah, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mohammadi-Rick, S; Rahimian, R; Shabanzadeh, AP, 2011) |
| "Stroke was rendered in rats by introduction of an autologous clot into the middle cerebral artery (MCA)." | 1.37 | Tropisetron ameliorates ischemic brain injury in an embolic model of stroke. ( Barzegar-Fallah, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mohammadi-Rick, S; Rahimian, R; Shabanzadeh, AP, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rahimian, R | 1 |
| Daneshmand, A | 1 |
| Mehr, SE | 1 |
| Barzegar-Fallah, A | 1 |
| Mohammadi-Rick, S | 1 |
| Fakhfouri, G | 1 |
| Shabanzadeh, AP | 1 |
| Dehpour, AR | 1 |
1 other study available for biguanides and Brain Edema
| Article | Year |
|---|---|
Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.
Topics: Analysis of Variance; Animals; Biguanides; Blood Gas Analysis; Brain Edema; Brain Infarction; Brain | 2011 |