biguanides has been researched along with Bradyarrhythmia in 25 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mean arterial pressure (MAP), heart rate (HR), and renal sympathetic nerve activity (RSNA) were measured in conscious rats during either hemorrhage or cardiopulmonary chemoreceptor stimulation with phenylbiguanide (PBG) after intracerebroventricular injection of the 5-HT1/5-HT2-receptor antagonist, methysergide (40 micrograms)." | 7.70 | Central methysergide prevents renal sympathoinhibition and bradycardia during hypotensive hemorrhage. ( Johnson, AK; Scrogin, KE; Veelken, R, 1998) |
| " The role of central 5-HT(1A) receptors in the control of the bradycardia and changes in central respiratory drive, renal nerve activity and blood pressure evoked by stimulating cardiopulmonary afferents with phenylbiguanide, baroreceptors by electrical stimulation of the aortic nerve and chemoreceptors by injections of sodium cyanide (NaCN) in atenolol-pretreated anaesthetized rabbits were studied." | 3.71 | Modulation of reflexly evoked vagal bradycardias by central 5-HT1A receptors in anaesthetized rabbits. ( Jordan, D; Ramage, AG; Skinner, MR, 2002) |
| " Intravenous (iv) injection of PDG (10 microg/kg), produced hypotension, bradycardia and apnea over a period of time." | 3.70 | Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats. ( Bagchi, S; Deshpande, SB, 2000) |
| "Mean arterial pressure (MAP), heart rate (HR), and renal sympathetic nerve activity (RSNA) were measured in conscious rats during either hemorrhage or cardiopulmonary chemoreceptor stimulation with phenylbiguanide (PBG) after intracerebroventricular injection of the 5-HT1/5-HT2-receptor antagonist, methysergide (40 micrograms)." | 3.70 | Central methysergide prevents renal sympathoinhibition and bradycardia during hypotensive hemorrhage. ( Johnson, AK; Scrogin, KE; Veelken, R, 1998) |
| " Apnea followed by rapid shallow breathing was observed in most animals." | 3.66 | Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets. ( Gootman, N; Gootman, PM; Schleman, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 10 (40.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eme, J | 1 |
| Tate, KB | 1 |
| Rhen, T | 1 |
| Crossley, DA | 1 |
| Netzer, F | 1 |
| Mandjee, N | 1 |
| Verberne, AJ | 1 |
| Bernard, JF | 1 |
| Hamon, M | 1 |
| Laguzzi, R | 1 |
| Sévoz-Couche, C | 1 |
| Futuro Neto, HA | 1 |
| Macedo, SM | 1 |
| Silva, NF | 1 |
| Cabral, AM | 1 |
| Pires, JG | 2 |
| Thomas, CJ | 2 |
| Sharma, AD | 2 |
| Woods, RL | 3 |
| Tjen-A-Looi, SC | 1 |
| Li, P | 1 |
| Li, M | 1 |
| Longhurst, JC | 1 |
| Cisternas, JR | 1 |
| Valenti, VE | 1 |
| Sato, MA | 1 |
| Fonseca, FL | 1 |
| Saldiva, PH | 1 |
| De Mello Monteiro, CB | 1 |
| Neto, ML | 1 |
| Rodrigues, LM | 1 |
| De Abreu, LC | 1 |
| Skinner, MR | 1 |
| Ramage, AG | 3 |
| Jordan, D | 2 |
| Bagchi, S | 2 |
| Deshpande, SB | 2 |
| COMROE, JH | 1 |
| MORTIMER, L | 1 |
| Abdala, AP | 1 |
| Schoorlemmer, GH | 1 |
| Colombari, E | 1 |
| Toader, E | 1 |
| McAllen, RM | 1 |
| Cividjian, A | 1 |
| Quintin, L | 1 |
| Skofitsch, G | 1 |
| Saria, A | 1 |
| Lembeck, F | 1 |
| Chen, CY | 1 |
| DiCarlo, SE | 1 |
| Collins, HL | 1 |
| Scrogin, KE | 1 |
| Veelken, R | 1 |
| Johnson, AK | 1 |
| Paton, JF | 3 |
| Silva-Carvalho, L | 1 |
| Rocha, I | 1 |
| Goldsmith, GE | 1 |
| Spyer, KM | 1 |
| Silva, SR | 1 |
| Futuro-Neto, HA | 1 |
| Rai, OP | 1 |
| Aryya, NC | 1 |
| Wang, Y | 1 |
| Jones, JF | 1 |
| Jeggo, RD | 1 |
| de Burgh Daly, M | 1 |
| Edwards, E | 1 |
| May, CN | 1 |
| Gordon, FJ | 1 |
| Wacker, MJ | 1 |
| Tehrani, RN | 1 |
| Smoot, RL | 1 |
| Orr, JA | 1 |
| Schleman, M | 1 |
| Gootman, N | 1 |
| Gootman, PM | 1 |
| Giles, TD | 1 |
| Sander, GE | 1 |
25 other studies available for biguanides and Bradyarrhythmia
| Article | Year |
|---|---|
Cardiovascular responses to putative chemoreceptor stimulation of embryonic common snapping turtles (Chelydra serpentina) chronically incubated in hypoxia (10% O
Topics: Animals; Biguanides; Blood Pressure; Bradycardia; Cardiovascular System; Chemoreceptor Cells; Heart | 2021 |
Inhibition of the bradycardic component of the von Bezold-Jarisch reflex and carotid chemoreceptor reflex by periaqueductal gray stimulation: involvement of medullary receptors.
Topics: Animals; Bicuculline; Biguanides; Bradycardia; Carotid Arteries; Chemoreceptor Cells; GABA Antagonis | 2009 |
Central 5-HT(2A) receptors modulate the vagal bradycardia in response to activation of the von Bezold-Jarisch reflex in anesthetized rats.
Topics: Analgesics; Animals; Atenolol; Biguanides; Bradycardia; Male; Rats; Rats, Wistar; Receptor, Serotoni | 2011 |
Do prostanoids or nitric oxide mediate sensitization of the von Bezold-Jarisch reflex by B-type natriuretic peptide?
Topics: Animals; Awareness; Biguanides; Bradycardia; Chemoreceptor Cells; Heart; Indomethacin; Natriuretic P | 2011 |
Modulation of cardiopulmonary depressor reflex in nucleus ambiguus by electroacupuncture: roles of opioids and γ-aminobutyric acid.
Topics: Analgesics, Opioid; Animals; Biguanides; Blood Pressure; Bradycardia; Cardiovascular System; Cats; E | 2012 |
The effects of catalase inhibition into the fourth cerebral ventricle on the Bezold-Jarisch reflex in spontaneously hypertensive rats.
Topics: Amitrole; Analgesics; Analysis of Variance; Animals; Biguanides; Blood Pressure; Bradycardia; Enzyme | 2011 |
Modulation of reflexly evoked vagal bradycardias by central 5-HT1A receptors in anaesthetized rabbits.
Topics: Anesthesia; Animals; Atenolol; Biguanides; Blood Pressure; Bradycardia; Buspirone; Chemoreceptor Cel | 2002 |
Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Apnea; Biguanides; Blood Pressure; Bradyc | 2000 |
THE RESPIRATORY AND CARDIOVASCULAR RESPONSES OF TEMPORALLY SEPARATED AORTIC AND CAROTID BODIES TO CYANIDE, NICOTINE, PHENYLDIGUANIDE AND SEROTONIN.
Topics: Amidines; Animals; Biguanides; Blood Pressure; Bradycardia; Carotid Body; Cyanides; Dogs; Heart; Hyp | 1964 |
Ablation of NK1 receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats.
Topics: Animals; Baroreflex; Biguanides; Blood Pressure; Bradycardia; Cardiovascular Physiological Phenomena | 2006 |
Effect of systemic B-type natriuretic peptide on cardiac vagal motoneuron activity.
Topics: Action Potentials; Animals; Baroreflex; Biguanides; Bradycardia; Dose-Response Relationship, Drug; E | 2007 |
Phenyldiguanide and capsaicin stimulate functionally different populations of afferent C-fibers.
Topics: Animals; Apnea; Biguanides; Bradycardia; Capillary Permeability; Capsaicin; Hypotension; Male; Nerve | 1983 |
Enhanced cardiopulmonary reflex inhibition of heart rate during exercise.
Topics: Analysis of Variance; Animals; Biguanides; Blood Pressure; Blood Volume; Bradycardia; Heart; Heart R | 1995 |
Central methysergide prevents renal sympathoinhibition and bradycardia during hypotensive hemorrhage.
Topics: Animals; Biguanides; Blood Pressure; Bradycardia; Cerebral Ventricles; Chemoreceptor Cells; Denervat | 1998 |
Pattern of cardiorespiratory afferent convergence to solitary tract neurons driven by pulmonary vagal C-fiber stimulation in the mouse.
Topics: Afferent Pathways; Animals; Biguanides; Blood Pressure; Bradycardia; Carotid Body; Heart; Heart Rate | 1998 |
Convergence properties of solitary tract neurons responsive to cardiac receptor stimulation in the anesthetized cat.
Topics: Afferent Pathways; Anesthesia; Animals; Biguanides; Bradycardia; Carotid Body; Carotid Sinus; Cats; | 1998 |
Evidence that 5-HT3 receptors in the nucleus tractus solitarius and other brainstem areas modulate the vagal bradycardia evoked by activation of the von Bezold-Jarisch reflex in the anesthetized rat.
Topics: Anesthetics; Animals; Biguanides; Bradycardia; Brain Stem; Cisterna Magna; Granisetron; Injections; | 1998 |
Pulmonary oedema produced by scorpion venom augments a phenyldiguanide-induced reflex response in anaesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Apnea; Aprotinin; Biguanides; Bradycardia; Drug Synergism; Female | 1999 |
Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats.
Topics: Action Potentials; Anesthesia; Animals; Autonomic Fibers, Preganglionic; Axons; Biguanides; Bradycar | 2000 |
Glutamate stimulation of raphe pallidus attenuates the cardiopulmonary reflex in anaesthetised rats.
Topics: Anesthesia; Animals; Biguanides; Blood Pressure; Bradycardia; Glutamic Acid; Heart Rate; Male; Micro | 2000 |
ANP, BNP, and CNP enhance bradycardic responses to cardiopulmonary chemoreceptor activation in conscious sheep.
Topics: Animals; Atrial Natriuretic Factor; Baroreflex; Biguanides; Blood Pressure; Bradycardia; Chemorecept | 2001 |
Effect of nucleus tractus solitarius lesions on fever produced by interleukin-1beta.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Biguanides; Bradycardia; Cold Temperature; | 2000 |
Thromboxane A(2) mimetic evokes a bradycardia mediated by stimulation of cardiac vagal afferent nerves.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthesia; Animals; Biguanides; | 2002 |
Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets.
Topics: Anesthesia, Inhalation; Animals; Animals, Newborn; Aorta; Apnea; Biguanides; Blood Pressure; Bradyca | 1979 |
Comparative cardiovascular responses to intravenous capsaicin, phenyldiguanide, veratrum alkaloids and enkephalins in the conscious dog.
Topics: Animals; Biguanides; Blood Pressure; Bradycardia; Capsaicin; Cardiovascular System; Chemoreceptor Ce | 1986 |