biguanides has been researched along with Body Weight in 53 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic treatment of female rats with buformin (k mg/day per rat) is shown to decrease the body weight, to increase the average life span by 9% and to reduce the incidence of spontaneous tumors." | 3.66 | [Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats]. ( Anisimov, VN, 1980) |
| "Weight loss was observed with dulaglutide in combination with BG alone or with SU + BG." | 2.82 | The combination of dulaglutide and biguanide reduced bodyweight in Japanese patients with type 2 diabetes. ( Araki, E; Inagaki, N; Matsui, A; Oura, T; Takeuchi, M; Tanizawa, Y, 2016) |
| " The most frequent adverse events with dulaglutide treatment were nasopharyngitis and gastrointestinal symptoms." | 2.80 | Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study. ( Araki, E; Imaoka, T; Inagaki, N; Oura, T; Takeuchi, M; Tanizawa, Y, 2015) |
| "The secondary and adverse effects when biguanides, alpha-glycosidase inhibitor or thiazolidine derivative was used with sulphonylurea agent (SU) as compared with those with SU alone in Type 2 diabetes patients by using Systematic Review." | 2.44 | Lipids behavior and adverse effects for oral antidiabetic agents in patients with Type 2 diabetes treated with sulfonylureas alone based on systematic review. ( Eto, M; Katsuyama, S; Miura, M; Mohri, K; Mouri, K; Mukai, J; Shoji, T; Suzuki, T; Tada, H; Watanabe, Y, 2007) |
| "The majority of patients with type 2 diabetes mellitus are overweight or obese at the time of diagnosis, and obesity is a recognised risk factor for type 2 diabetes and coronary heart disease (CHD)." | 2.44 | Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus. ( Hermansen, K; Mortensen, LS, 2007) |
| "We enrolled 106 patients with type 2 diabetes mellitus (T2DM), treated with liraglutide (N." | 1.40 | Multiple drug combination of anti-diabetic agents as a predictor for poor clinical response to liraglutide. ( Abiru, N; Ando, T; Fujishima, K; Haraguchi, A; Imaizumi, M; Kawakami, A; Matsumoto, K; Mori, F; Takamura, N; Yamasaki, H, 2014) |
| "we studied a group of 268 patients with type 2 diabetes, aged between 30 and 50 years, with a diabetes duration of less than 5 years." | 1.32 | The value of basal C peptide and its relationship with pancreatic autoantibodies in young adults with type 2 diabetes mellitus. ( Roşu, M; Serban, V; Sima, A; Timar, R; Vlad, A, 2004) |
| " Dose-response curves to chemical stimulation (spikes/s vs." | 1.29 | Daily spontaneous running did not alter vagal afferent reactivity. ( Collins, HL; DiCarlo, SE; Scislo, TJ, 1993) |
| " Among the sulfonamide derivatives are preparations which are highly effective, low dosed and have few side effects." | 1.25 | [Twenty years of oral diabetic therapy (author's transl)]. ( Dietze, G; Mehnert, H, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (81.13) | 18.7374 |
| 1990's | 1 (1.89) | 18.2507 |
| 2000's | 4 (7.55) | 29.6817 |
| 2010's | 5 (9.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haraguchi, A | 1 |
| Fujishima, K | 1 |
| Ando, T | 1 |
| Mori, F | 1 |
| Imaizumi, M | 1 |
| Abiru, N | 1 |
| Yamasaki, H | 1 |
| Matsumoto, K | 1 |
| Takamura, N | 1 |
| Kawakami, A | 1 |
| Araki, E | 2 |
| Inagaki, N | 2 |
| Tanizawa, Y | 2 |
| Oura, T | 2 |
| Takeuchi, M | 2 |
| Imaoka, T | 1 |
| Matsui, A | 1 |
| Bezerra, VM | 1 |
| Xavier, CH | 1 |
| de Menezes, RC | 1 |
| Fontes, MA | 1 |
| Cardoso, LM | 1 |
| Fernandes, LG | 1 |
| Chianca, DA | 1 |
| Kawamori, R | 1 |
| Vlad, A | 1 |
| Serban, V | 1 |
| Sima, A | 1 |
| Timar, R | 1 |
| Roşu, M | 1 |
| Purnell, JQ | 1 |
| Weyer, C | 1 |
| Mukai, J | 1 |
| Tada, H | 1 |
| Watanabe, Y | 1 |
| Miura, M | 1 |
| Katsuyama, S | 1 |
| Shoji, T | 1 |
| Mohri, K | 1 |
| Mouri, K | 1 |
| Eto, M | 1 |
| Suzuki, T | 1 |
| Hermansen, K | 1 |
| Mortensen, LS | 1 |
| Siitonen, O | 1 |
| Aro, A | 1 |
| Huttunen, JK | 1 |
| Juvonen, H | 1 |
| Järvinen, R | 1 |
| Korhonen, T | 1 |
| Palomäki, P | 1 |
| Ritala, P | 1 |
| Breidahl, HD | 2 |
| Schernthaner, G | 1 |
| Prager, R | 1 |
| Pissarek, D | 1 |
| Panzram, G | 2 |
| Lundershausen, R | 1 |
| Adolph, W | 1 |
| Senf, L | 1 |
| Anisimov, VN | 1 |
| Vogelberg, KH | 1 |
| Cicmir, I | 1 |
| Heggen, ME | 1 |
| Scislo, TJ | 1 |
| DiCarlo, SE | 1 |
| Collins, HL | 1 |
| Irvine, WJ | 1 |
| McCallum, CJ | 1 |
| Gray, RS | 1 |
| Duncan, LJ | 1 |
| Papoz, L | 1 |
| Job, D | 1 |
| Eschwege, E | 1 |
| Aboulker, JP | 1 |
| Cubeau, J | 1 |
| Pequignot, G | 1 |
| Rathery, M | 1 |
| Rosselin, G | 1 |
| Koschinsky, T | 1 |
| Gries, FA | 1 |
| Schwandt, P | 1 |
| Weisweiler, P | 1 |
| Hansen, W | 1 |
| Nijssen, J | 1 |
| Beckmann, R | 1 |
| Bloom, A | 1 |
| Estivals, JP | 1 |
| Giraudet, MC | 1 |
| Videau, JY | 1 |
| Schatz, H | 1 |
| Winkler, G | 1 |
| Jonatha, EM | 1 |
| Pfeiffer, EF | 1 |
| Mehnert, H | 1 |
| Dietze, G | 1 |
| Zilker, T | 1 |
| Kränzlin, T | 1 |
| Schweigart, U | 1 |
| Ermler, R | 1 |
| Bottermann, P | 1 |
| Dil'man, VM | 1 |
| Bershteĭn, LM | 1 |
| Tsyrlina, EV | 1 |
| Bobrov, IuF | 1 |
| Kovaleva, IG | 1 |
| Walsh, CH | 1 |
| Soler, NG | 1 |
| James, H | 1 |
| Fitzgerald, MG | 1 |
| Malins, JM | 1 |
| Mackenzie, IC | 1 |
| Codaccioni, JL | 1 |
| Kornman, KS | 1 |
| Clark, WB | 1 |
| Kreitzman, SN | 1 |
| Alvarez, C | 1 |
| Ennis, GC | 1 |
| Martin, FI | 1 |
| Stawell, JR | 1 |
| Taft, P | 1 |
| Hockaday, TD | 1 |
| Bäbler, M | 1 |
| Rojszykowa, E | 1 |
| Wechsler, B | 1 |
| Kopp, H | 1 |
| Leubner, H | 1 |
| Dub, O | 1 |
| Brozek, I | 1 |
| Pátek, F | 1 |
| Irsigler, K | 2 |
| Flegel, U | 1 |
| Pogátsa, G | 1 |
| McKiddie, MT | 1 |
| Buchanan, KD | 1 |
| Hunter, IA | 1 |
| Klein, W | 1 |
| Hole, P | 1 |
| Dietzmann, HB | 1 |
| Buding, A | 1 |
| Ricketts, HT | 1 |
| Gyr, K | 1 |
| Berger, W | 2 |
| Göschke, H | 1 |
| Stalder, GA | 1 |
| Rosenkranz, A | 1 |
| Takeda, M | 1 |
| Nishikawa, K | 1 |
| Miki, S | 1 |
| Fujii, Y | 1 |
| Tatsumi, K | 1 |
| Bittnerová, H | 1 |
| Masek, J | 1 |
| Rath, R | 1 |
| Haese, E | 1 |
| Kaeding, A | 1 |
| Werner, P | 1 |
| Constam, GR | 1 |
| Siegenthaler, W | 1 |
7 reviews available for biguanides and Body Weight
| Article | Year |
|---|---|
Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity.
Topics: Amyloid; Benzamides; Biguanides; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes | 2003 |
Lipids behavior and adverse effects for oral antidiabetic agents in patients with Type 2 diabetes treated with sulfonylureas alone based on systematic review.
Topics: Administration, Oral; Biguanides; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; | 2007 |
Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus.
Topics: Amyloid; Benzamides; Biguanides; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inh | 2007 |
[Insulin receptor and postreceptor disorders: significance for the development and therapy of carbohydrate metabolic disorders].
Topics: Autoantibodies; Biguanides; Body Weight; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus; | 1984 |
Some practical aspects of the management of diabetes.
Topics: Adult; Biguanides; Body Weight; Child; Contraceptives, Oral; Diabetes Complications; Diabetes Mellit | 1977 |
Insulin and oral hypoglycaemic agents. I. Physiological and clinical pharmacological aspects.
Topics: Administration, Oral; Biguanides; Body Weight; Carbohydrate Metabolism; Chemical Phenomena; Chemistr | 1972 |
Diabetes mellitus.
Topics: Alcohol Drinking; Anxiety; Biguanides; Blood Glucose; Blood Pressure; Body Weight; Cholesterol, Diet | 1974 |
12 trials available for biguanides and Body Weight
| Article | Year |
|---|---|
Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study.
Topics: Aged; Biguanides; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Administration Schedul | 2015 |
The combination of dulaglutide and biguanide reduced bodyweight in Japanese patients with type 2 diabetes.
Topics: Asian People; Biguanides; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combi | 2016 |
[Intensified therapy of newly detected maturity onset diabetes].
Topics: Biguanides; Body Weight; Clofibrate; Diabetes Mellitus; Diet, Diabetic; Female; Glucose Tolerance Te | 1980 |
[The influence of clofibrate on elevated serum lactate levels in diabetic patients treated with biguanides (author's transl)].
Topics: Adult; Biguanides; Body Weight; Clofibrate; Diabetes Mellitus; Enzymes; Female; Humans; Hypoglycemic | 1980 |
Effect of oral hypoglycaemic drugs on glucose tolerance and insulin secretion in borderline diabetic patients.
Topics: Administration, Oral; Adult; Biguanides; Blood Glucose; Body Weight; Clinical Trials as Topic; Doubl | 1978 |
[Treatment of primary hyperlipoproteinemias of type IIB and IV with butylbiguanide and clofibrate (author's transl)].
Topics: Adult; Aged; Biguanides; Blood Glucose; Body Weight; Buformin; Cholesterol; Clofibrate; Drug Therapy | 1977 |
[Survey of 832 case records of diabetes of adult onset treated by Diamicron. Evolution of metabolism and weight].
Topics: Adult; Aged; Biguanides; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes Mellitus; Fe | 1978 |
[Results of diabetes therapy with Silubin retard].
Topics: Adolescent; Adult; Biguanides; Blood Glucose; Body Weight; Carbohydrate Metabolism; Cholesterol; Cli | 1966 |
[Clinical report of the experience in therapy with oral antidiabetic agent HB 419].
Topics: Adult; Age Factors; Aged; Biguanides; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes | 1969 |
[Effect of metformin on glucose utilization and body weight].
Topics: Biguanides; Blood Glucose; Body Weight; Glucose; Glucose Tolerance Test; Humans; Injections, Intrave | 1970 |
[Postprandial disorders following gastrectomy and their modifications by dimethylbiguanide].
Topics: Adult; Anemia, Hypochromic; Antisocial Personality Disorder; Biguanides; Blood Glucose; Body Weight; | 1970 |
[The importance of the biguanides in the treatment of obesity].
Topics: Adult; Appetite Depressants; Biguanides; Blood Glucose; Body Weight; Cholesterol; Diet, Reducing; Fa | 1969 |
34 other studies available for biguanides and Body Weight
| Article | Year |
|---|---|
Multiple drug combination of anti-diabetic agents as a predictor for poor clinical response to liraglutide.
Topics: Adult; Aged; Alanine Transaminase; Anthropometry; Biguanides; Body Weight; Comorbidity; Diabetes Mel | 2014 |
Bezold-Jarisch reflex in sino-aortic denervated malnourished rats.
Topics: Animals; Atropine Derivatives; Biguanides; Blood Pressure; Body Weight; Denervation; Dose-Response R | 2011 |
[Biguanide, pioglitazone and alpha-glucosidase inhibitors].
Topics: Acidosis, Lactic; Biguanides; Body Weight; Chemical and Drug Induced Liver Injury; Digestive System; | 2012 |
The value of basal C peptide and its relationship with pancreatic autoantibodies in young adults with type 2 diabetes mellitus.
Topics: Adult; Autoantibodies; Biguanides; Biomarkers; Body Mass Index; Body Weight; C-Peptide; Diabetes Mel | 2004 |
Effect of discontinuation of biguanide therapy on metabolic control in maturity-onset diabetics.
Topics: Aged; Biguanides; Blood Glucose; Body Weight; Diabetes Mellitus; Drug Therapy, Combination; Female; | 1980 |
What patients with diabetes want to know about their therapy.
Topics: Biguanides; Body Weight; Diabetes Mellitus; Dietary Fiber; Humans; Hypoglycemic Agents; Insulin; Pat | 1980 |
UK prospective study of therapies of maturity-onset diabetes. I. Effect of diet, sulphonylurea, insulin or biguanide therapy on fasting plasma glucose and body weight over one year.
Topics: Adult; Aged; Biguanides; Blood Glucose; Body Weight; Diabetes Mellitus; Diet; Female; Humans; Insuli | 1983 |
[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats].
Topics: Animals; Biguanides; Body Weight; Buformin; Estrus; Female; Longevity; Neoplasms, Experimental; Phen | 1980 |
Daily spontaneous running did not alter vagal afferent reactivity.
Topics: Afferent Pathways; Analysis of Variance; Animals; Biguanides; Blood Pressure; Body Weight; Female; H | 1993 |
Clinical and pathogenic significance of pancreatic-islet-cell antibodies in diabetics treated with oral hypoglycaemic agents.
Topics: Administration, Oral; Adolescent; Adult; Aged; Autoantibodies; Autoimmune Diseases; Biguanides; Body | 1977 |
[Proceedings: Juvenile diabetic patients. Control of stabilizing in various forms of therapy].
Topics: Adolescent; Age Factors; Biguanides; Blood Glucose; Body Weight; Child; Circadian Rhythm; Diabetes M | 1975 |
[Twenty years of oral diabetic therapy (author's transl)].
Topics: Administration, Oral; Biguanides; Blood Glucose; Body Weight; Chemistry; Diabetes Mellitus; Drug The | 1975 |
[Radioimmunological determination of insulin in patients with manifest diabetes mellitus as a guide for the planning of therapy (author's transl)].
Topics: Biguanides; Blood Glucose; Body Weight; Diabetes Mellitus; Female; Glucose Tolerance Test; Glyburide | 1976 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C | 1975 |
Studies on whole-body potassium in non-ketoacidotic diabetics before and after treatment.
Topics: Adolescent; Adult; Aged; Biguanides; Body Composition; Body Weight; Diabetes Mellitus; Female; Human | 1974 |
The effects of oral administration of chlorhexidine on the rate of regeneration of epithelia of the oral mucosa and skin of mice.
Topics: Administration, Oral; Animals; Autoradiography; Biguanides; Body Weight; Cell Division; Cell Movemen | 1974 |
[What is the status of the oral treatment of diabetes?].
Topics: Biguanides; Body Weight; Diabetes Mellitus; Diet Therapy; Humans; Hypoglycemic Agents | 1967 |
[Possibilities and limits of primary prevention in diabetes mellitus].
Topics: Biguanides; Body Weight; Diabetes Mellitus; Diabetic Angiopathies; Dietary Carbohydrates; Female; Hu | 1974 |
Caries control in the albino rat with chlorhexidine gluconate (Hibitane).
Topics: Alopecia; Animals; Biguanides; Body Weight; Dental Caries; Dental Enamel; Drinking Behavior; Rats; W | 1973 |
[Diabetes mellitus and obesity: monotherapy using biguanides].
Topics: Adult; Biguanides; Body Weight; Child; Diabetes Mellitus; Diarrhea; Diet Therapy; Flatulence; Humans | 1973 |
[Biguanide derivative monotherapy in diabetes].
Topics: Adult; Aged; Biguanides; Body Weight; Cholesterol; Diabetes Mellitus; Female; Humans; Male; Middle A | 1973 |
[Management of diabetes mellitus].
Topics: Adult; Aged; Biguanides; Body Weight; Diabetes Mellitus; Diet Therapy; Humans; Hyperglycemia; Insuli | 1974 |
[Silubin retard--long-term effects].
Topics: Adult; Aged; Biguanides; Blood Proteins; Body Weight; Cholesterol; Delayed-Action Preparations; Diab | 1971 |
[Antilipidemic agents].
Topics: Adult; Alcohols; Anticholesteremic Agents; Biguanides; Blood Protein Disorders; Body Weight; Cholest | 1971 |
New data on Adebit treatment of diabetes.
Topics: Biguanides; Body Weight; Butanes; Diabetes Mellitus; Drug Therapy, Combination; Humans; Hypoglycemic | 1971 |
Plasma insulin studies in two hundred patients with diabetes mellitus.
Topics: Acidosis; Adult; Age Factors; Aged; Biguanides; Blood Glucose; Body Weight; Diabetes Mellitus; Diabe | 1969 |
[Biguanide treatment of diabetics. Effect on body weight--tolerance].
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Biguanides; Body Weight; Diabetes Me | 1969 |
Weight change with orally administered "antidiabetic" drugs.
Topics: Adipose Tissue; Administration, Oral; Animals; Biguanides; Body Weight; Diabetes Mellitus; Diet; Fem | 1970 |
[Possibilities and limitations of oral therapy in juvenile diabetes mellitus].
Topics: Biguanides; Body Weight; Child; Diabetes Mellitus, Type 1; Drug Synergism; Female; Humans; Insulin; | 1968 |
[Treatment of diabetics by biguanide--its applicability with special reference to clinical observations].
Topics: Adolescent; Adult; Aged; Biguanides; Blood Glucose; Body Weight; Carbohydrates; Cholesterol; Diabete | 1968 |
[Oral therapy of diabetes].
Topics: Adolescent; Adult; Aged; Biguanides; Blood Glucose; Body Weight; Child; Diabetes Complications; Diab | 1969 |
[On the clinical use of biguanides].
Topics: Aged; Biguanides; Blood Glucose; Body Weight; Cholesterol; Depression, Chemical; Diabetes Mellitus; | 1969 |
[Late failures of oral therapy of diabetes].
Topics: Age Factors; Biguanides; Body Weight; Carbutamide; Diabetes Mellitus; Glycosuria; Humans; Hypoglycem | 1965 |
[Therapeutic possibilities in diabetes mellitus with biguanides. Clinical experiences in 122 diabetics with dimethylbiguanide(Glucophage)].
Topics: Adolescent; Adult; Biguanides; Body Weight; Chemical Phenomena; Chemistry; Diabetes Mellitus; Diet, | 1966 |