Page last updated: 2024-11-08

biguanides and Bacterial Disease

biguanides has been researched along with Bacterial Disease in 18 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Research Excerpts

ExcerptRelevanceReference
"This study compares treatment with a polihexanide-containing biocellulose wound dressing (BWD+PHMB) versus the best local standard of silver dressings (Ag) in painful, critically colonised (wounds-at-risk) or locally-infected wounds."5.16Comparison of PHMB-containing dressing and silver dressings in patients with critically colonised or locally infected wounds. ( Abel, M; Eberlein, T; Gruber Moesenbacher, U; Haemmerle, G; Mittlboeck, M; Signer, M; Strohal, R; Traber, J, 2012)
"The exposure of human osteoblasts and endothelial cells to polyhexanide at concentrations with questionable antibacterial activity resulted in severe cell damage whereas exposure to high dosed gentamicin did not."1.34Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells. ( Eulert, J; Hendrich, C; Ince, A; Jakob, F; Löhr, JF; Schütze, N, 2007)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's7 (38.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Barreto, R1
Barrois, B1
Lambert, J1
Malhotra-Kumar, S1
Santos-Fernandes, V1
Monstrey, S1
Zheng, Y1
Wang, D1
Ma, LZ1
Ceviker, K1
Canikoglu, M1
Tatlıoglu, S1
Bagdatli, Y1
Taylor, BJ1
Marsh, LL1
Nosworthy, JO1
Williams, DW1
Reddersen, K1
Finger, S1
Zieger, M1
Wiegand, C1
Buschmann, HJ1
Elsner, P1
Hipler, UC1
Geraldo, IM1
Gilman, A1
Shintre, MS1
Modak, SM1
Drake, GJ1
Koeppel, K1
Barrows, M1
Dissemond, J1
Gerber, V1
Kramer, A1
Riepe, G1
Strohal, R2
Vasel-Biergans, A1
Eberlein, T2
Haemmerle, G1
Signer, M1
Gruber Moesenbacher, U1
Traber, J1
Mittlboeck, M1
Abel, M1
Oulé, MK1
Quinn, K1
Dickman, M1
Bernier, AM1
Rondeau, S1
De Moissac, D1
Boisvert, A1
Diop, L1
Fabry, W2
Trampenau, C1
Bettag, C2
Handschin, AE1
Lettgen, B1
Huber, FX1
Hillmeier, J1
Kock, HJ2
Ince, A1
Schütze, N1
Hendrich, C1
Jakob, F1
Eulert, J1
Löhr, JF1
Hingst, V1
Klippel, KM1
Sonntag, HG1
Schmit-Neuerburg, KP1
Schlickewei, W1
Hanke, J1
Renzing-Köhler, K1
Hirche, H1
Honigman, JL1
Farris, RL1
Davies, RM1
Bocarnea, C1
Duminica, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
THE EFFECT OF USING CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE SOLUTION ON THE HEALING PROCESS BEFORE A CESAREAN SECTION[NCT05953714]102 participants (Actual)Interventional2020-12-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for biguanides and Bacterial Disease

ArticleYear
Addressing the challenges in antisepsis: focus on povidone iodine.
    International journal of antimicrobial agents, 2020, Volume: 56, Issue:3

    Topics: Anti-Infective Agents, Local; Bacteria; Bacterial Infections; Biguanides; Biofilms; Chlorhexidine; H

2020
Is your office safe? No.
    Cornea, 1990, Volume: 9 Suppl 1

    Topics: Accident Prevention; Bacterial Infections; Biguanides; Chlorhexidine; Contact Lenses; Disinfection;

1990

Trials

5 trials available for biguanides and Bacterial Disease

ArticleYear
Reducing the pathogen burden and promoting healing with polyhexanide in non-healing wounds: a prospective study.
    Journal of wound care, 2015, Volume: 24, Issue:12

    Topics: Aged; Anti-Infective Agents, Local; Bacterial Infections; Biguanides; C-Reactive Protein; Cohort Stu

2015
Comparison of PHMB-containing dressing and silver dressings in patients with critically colonised or locally infected wounds.
    Journal of wound care, 2012, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Bacterial Infections; Bacterial Load;

2012
Bacterial decontamination of surgical wounds treated with Lavasept.
    International journal of hygiene and environmental health, 2006, Volume: 209, Issue:6

    Topics: Bacterial Infections; Biguanides; Colony Count, Microbial; Disinfectants; Double-Blind Method; Gram-

2006
[Effectiveness of an improved antiseptic in treatment of contaminated soft tissue wounds].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2001, Volume: 72, Issue:1

    Topics: Adult; Aged; Anti-Infective Agents, Local; Bacterial Infections; Biguanides; Double-Blind Method; Fe

2001
[Guamecycline in the treatment of acute pneumopathies. Clinical research and comparison with other tetracyclines].
    Minerva medica, 1972, Nov-21, Volume: 63, Issue:83

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Biguanides; Clinical Trials as Topic;

1972

Other Studies

11 other studies available for biguanides and Bacterial Disease

ArticleYear
Effect of Polyhexamethylene Biguanide in Combination with Undecylenamidopropyl Betaine or PslG on Biofilm Clearance.
    International journal of molecular sciences, 2021, Jan-14, Volume: 22, Issue:2

    Topics: Bacteria; Bacterial Infections; Betaine; Biguanides; Biofilms; Candida albicans; Candidiasis; Cross

2021
A novel approach to antibiofilm susceptibility testing using a thermo-reversible matrix.
    Journal of wound care, 2016, Volume: 25, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Biguanides; Biofilms; Carbonates

2016
Cytocompatibility testing of cyclodextrin-functionalized antimicrobial textiles-a comprehensive approach.
    Journal of materials science. Materials in medicine, 2016, Volume: 27, Issue:12

    Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Apoptosis; Bacterial Infections; Biguanides; Bi

2016
Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents.
    Infection control and hospital epidemiology, 2008, Volume: 29, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacterial Infections; Benzethonium; Bi

2008
Disinfectant (F10SC) nebulisation in the treatment of 'red leg syndrome' in amphibians.
    The Veterinary record, 2010, May-08, Volume: 166, Issue:19

    Topics: Animal Husbandry; Animals; Anura; Bacterial Infections; Biguanides; Disinfectants; Nebulizers and Va

2010
A practice-oriented recommendation for treatment of critically colonised and locally infected wounds using polihexanide.
    Journal of tissue viability, 2010, Volume: 19, Issue:3

    Topics: Acute Disease; Bacterial Infections; Biguanides; Chronic Disease; Contraindications; Disinfectants;

2010
Akwaton, polyhexamethylene-guanidine hydrochloride-based sporicidal disinfectant: a novel tool to fight bacterial spores and nosocomial infections.
    Journal of medical microbiology, 2012, Volume: 61, Issue:Pt 10

    Topics: Bacillus subtilis; Bacterial Infections; Bacteriological Techniques; Biguanides; Cross Infection; Di

2012
Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells.
    Swiss medical weekly, 2007, Mar-10, Volume: 137, Issue:9-10

    Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement

2007
[Epidemiology of microbial resistance to biocides].
    Zentralblatt fur Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine, 1995, Volume: 197, Issue:1-3

    Topics: Aldehydes; Anti-Infective Agents, Local; Bacteria; Bacterial Infections; Biguanides; Disinfectants;

1995
Letter: Chlorhexidine and the newborn.
    The Journal of antimicrobial chemotherapy, 1976, Volume: 2, Issue:1

    Topics: Bacterial Infections; Biguanides; Chlorhexidine; Humans; Infant, Newborn

1976
Bacteriological problems in general practice. Should the mucous membrane be sterilized before injection?
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:12 Pt 1

    Topics: Anesthesia, Dental; Anesthesia, Local; Anti-Infective Agents, Local; Bacterial Infections; Biguanide

1974