Page last updated: 2024-11-08

biguanides and Alloxan Diabetes

biguanides has been researched along with Alloxan Diabetes in 21 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Research Excerpts

ExcerptRelevanceReference
"In patients with diabetes mellitus, dermatophytosis is more severe and recurrent."1.72Antifungal activity of alexidine dihydrochloride in a novel diabetic mouse model of dermatophytosis. ( Date, A; Ibrahim, AS; Nabeela, S; Uppuluri, P, 2022)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199012 (57.14)18.7374
1990's1 (4.76)18.2507
2000's1 (4.76)29.6817
2010's5 (23.81)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Basyouni, WM4
Abbas, SY4
El-Bayouki, KAM2
Younis, EA1
Ali, SA1
Aly, HF3
Nabeela, S1
Date, A1
Ibrahim, AS1
Uppuluri, P1
El-Bayouk, KAM1
Tohamy, WM1
Arafa, A2
Soliman, MS2
El Shehry, MF1
Gupta, D1
Thangaraj, D1
Radhakrishnan, M1
El-Bayouki, KA1
Abdel-Rahman, RF1
McNamara, DB1
Murthy, SN1
Fonseca, AN1
Desouza, CV1
Kadowitz, PJ1
Fonseca, VA1
Sim, YB1
Park, SH1
Kang, YJ1
Kim, SS1
Kim, CH1
Kim, SJ1
Jung, JS1
Ryu, OH1
Choi, MG1
Suh, HW1
McDonald, HJ1
DeChatelet, LR1
Woo, LC1
Yuen, VG1
Thompson, KH1
McNeill, JH1
Orvig, C1
Nawar, NN1
Kamel, I1
Schoukri, NA1
Tutwiler, GF1
Bridi, G1
Losert, W2
Loge, O2
Schillinger, E2
Muntoni, S1
Kraaz, W1
Jahn, P1
Loiseau, G1
Millischer, R1
Berthe, G1
Donadieu, AM1
Lohier, P1
Marquet, JP1
Söling, HD2
Moshagen, D1
Skutella, E1
Kneer, P1
Creutzfeldt, W1
Förster, O1
Rudas, B2
Brand, J1
Novak, M1
Paul, SP1

Reviews

3 reviews available for biguanides and Alloxan Diabetes

ArticleYear
Animal models of catheter-induced intimal hyperplasia in type 1 and type 2 diabetes and the effects of pharmacologic intervention.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:1

    Topics: Animals; Biguanides; Catheterization; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Di

2009
Inhibition of fatty acid oxidation by biguanides: implications for metabolic physiopathology.
    Advances in lipid research, 1974, Volume: 12, Issue:0

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Biguanides; Biological Trans

1974
[The effects of blood glucose lowering biguanides on liver metabolism].
    Acta diabetologica latina, 1969, Volume: 6 Suppl 1

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Biguanides; Diabetes Mellitus, Experimental; Dogs; Glu

1969

Other Studies

18 other studies available for biguanides and Alloxan Diabetes

ArticleYear
Synthesis and hyperglycemic, biochemical and histopathological evaluation of novel sulfonylbiguanide and sulfonylurea derivatives as potent anti-diabetic agents.
    Bioorganic chemistry, 2021, Volume: 117

    Topics: Animals; Biguanides; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypoglycemic

2021
Antifungal activity of alexidine dihydrochloride in a novel diabetic mouse model of dermatophytosis.
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: Animals; Antifungal Agents; Biguanides; Diabetes Mellitus, Experimental; Disease Models, Animal; Mic

2022
New Biguanides as Anti-Diabetic Agents Part I: Synthesis and Evaluation of 1-Substituted Biguanide Derivatives as Anti-Diabetic Agents of Type II Diabetes Insulin Resistant.
    Drug research, 2017, Volume: 67, Issue:10

    Topics: Animals; Biguanides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents

2017
New Biguanides as Anti-Diabetic Agents, Part II: Synthesis and Anti-Diabetic Properties Evaluation of 1-Arylamidebiguanide Derivatives as Agents of Insulin Resistant Type II Diabetes.
    Archiv der Pharmazie, 2017, Volume: 350, Issue:11

    Topics: Administration, Oral; Animals; Biguanides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type

2017
A novel 5HT3 antagonist 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system.
    Behavioural brain research, 2016, Jan-15, Volume: 297

    Topics: Animals; Antidepressive Agents; Biguanides; Brain; Depressive Disorder; Diabetes Mellitus, Experimen

2016
Synthesis and Evaluation of 1-Substituted-Biguanide Derivatives as Anti-Diabetic Agents for Type II Diabetes Insulin Resistant.
    Drug research, 2016, Volume: 66, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biguanides; Blood Glucose; Cholesterol;

2016
Central anti-diabetic action of biguanide and thizolidinediones in D-glucose fed and streptozotocin-treated mouse models.
    Neuroscience letters, 2012, Oct-18, Volume: 528, Issue:1

    Topics: Animals; Biguanides; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type

2012
The effects of three oral hypoglycemic agents on the incorporation of leucine-C14 into protein by liver microsomes of normal and alloxan-diabetic rats.
    Life sciences, 1967, Jan-15, Volume: 6, Issue:2

    Topics: Animals; Biguanides; Carbon Isotopes; Chlorpropamide; Diabetes Mellitus, Experimental; Female; Leuci

1967
Vanadyl-biguanide complexes as potential synergistic insulin mimics.
    Journal of inorganic biochemistry, 1999, Sep-30, Volume: 76, Issue:3-4

    Topics: Animals; Biguanides; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Humans; Hypogly

1999
The histological changes in the diabetic adrenal gland after biguanide induced lactic acidosis.
    Singapore medical journal, 1979, Volume: 20, Issue:3

    Topics: Acidosis; Adrenal Glands; Animals; Biguanides; Diabetes Mellitus, Experimental; Lactates; Male; Nerv

1979
Comparison of McN-3495 [N-(1-methyl-2-pyrrolidinylidene)-N'-phenyl-1-pyrrolidinecarboximidamide], a new, orally effective, hypoglycemic agent, with the biguanides.
    Diabetes, 1978, Volume: 27, Issue:8

    Topics: Animals; Biguanides; Biological Transport, Active; Blood Glucose; Buformin; Diabetes Mellitus, Exper

1978
[Hypoglycemia induced by N1-(n-butyl)-biguanide (Buformin) in animal experiments].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1969, Volume: 264, Issue:3

    Topics: Animals; Arabinose; Biguanides; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemia; Hypogl

1969
[Studies on the mode of action of biguanides in animals. 4. Studies on gamma-guanidinobutyramide and summary].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:10

    Topics: Amides; Animals; Biguanides; Blood Glucose; Butyrates; Carbon Isotopes; Diabetes Mellitus, Experimen

1972
[A phosphorylated biguanide: benfosformin (JAV 852). I. Hypoglycemic and antidiabetic properties].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:11

    Topics: Animals; Benzyl Compounds; Biguanides; Blood Glucose; Diabetes Mellitus, Experimental; Hyperglycemia

1973
[The effect of N1, n-butylbiguanide on the metabolism of isolated perfused livers of normal and alloxan-diabetic ketotic rats].
    Diabetologia, 1967, Volume: 3, Issue:3

    Topics: Amino Acids; Animals; Biguanides; Bile; Depression, Chemical; Diabetes Mellitus, Experimental; Diabe

1967
The uptake of orally administered trioleate- 14 C in normal and diabetic rats with and without butylbiguanide application.
    Pharmacology, 1971, Volume: 6, Issue:2

    Topics: Adipose Tissue; Administration, Oral; Animals; Biguanides; Carbon Isotopes; Diabetes Mellitus, Exper

1971
The effect of butylbiguanide on the fat-induced hyperlipemia in normal and alloxan diabetic rats.
    Pharmacology, 1970, Volume: 3, Issue:6

    Topics: Animals; Biguanides; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glycerides; Glycer

1970
Effects of some synthetic biguanides on certain aspects of carbohydrate metabolism in alloxandiabetic mice.
    Journal of experimental medical sciences, 1966, Volume: 10, Issue:3

    Topics: Animals; Biguanides; Diabetes Mellitus, Experimental; Epinephrine; Glucose Tolerance Test; Liver Gly

1966