biguanides has been researched along with Adverse Drug Event in 6 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although formulated NB325 appeared generally safe for application in these studies, the low but observable level of toxicity suggests the need for improvements in the compound and/or formulation." | 1.37 | Cervicovaginal safety of the formulated, biguanide-based human immunodeficiency virus type 1 (HIV-1) inhibitor NB325 in a murine model. ( Kish-Catalone, T; Krebs, FC; Labib, M; Lozenski, K; Pirrone, V; Rando, RF; Wigdahl, B, 2011) |
| " At the same time about 1/3 of these serious adverse drug reactions (ADR) was found to have been reported to the ADR-register." | 1.27 | Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden. ( Westerholm, B; Wiholm, BE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Rida, E | 1 |
| Soulaymani, A | 1 |
| Serhier, Z | 1 |
| Hami, H | 1 |
| Abdelrhani, M | 1 |
| Landelle, C | 1 |
| von Dach, E | 1 |
| Haustein, T | 1 |
| Agostinho, A | 1 |
| Renzi, G | 1 |
| Renzoni, A | 1 |
| Pittet, D | 1 |
| Schrenzel, J | 1 |
| François, P | 1 |
| Harbarth, S | 1 |
| Lozenski, K | 1 |
| Kish-Catalone, T | 1 |
| Pirrone, V | 1 |
| Rando, RF | 1 |
| Labib, M | 1 |
| Wigdahl, B | 1 |
| Krebs, FC | 1 |
| Wiholm, BE | 1 |
| Westerholm, B | 1 |
| David, SA | 1 |
| Bechtel, B | 1 |
| Annaiah, C | 1 |
| Mathan, VI | 1 |
| Balaram, P | 1 |
| Okonek, S | 1 |
1 trial available for biguanides and Adverse Drug Event
| Article | Year |
|---|---|
Randomized, placebo-controlled, double-blind clinical trial to evaluate the efficacy of polyhexanide for topical decolonization of MRSA carriers.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Carrier State; Double-Blin | 2016 |
5 other studies available for biguanides and Adverse Drug Event
| Article | Year |
|---|---|
Antidiabetics and antihypertensive medications use in Morocco: A pharmacoepidemiological descriptive study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents | 2020 |
Cervicovaginal safety of the formulated, biguanide-based human immunodeficiency virus type 1 (HIV-1) inhibitor NB325 in a murine model.
Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Biguanides; Disease Models, Animal; Drug-Rel | 2011 |
Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden.
Topics: Acidosis; Aged; Anti-Infective Agents, Urinary; Biguanides; Congenital Abnormalities; Contraceptives | 1984 |
Interaction of cationic amphiphilic drugs with lipid A: implications for development of endotoxin antagonists.
Topics: Aminoquinolines; Biguanides; Biological Assay; Cations, Divalent; Drug-Related Side Effects and Adve | 1994 |
[On the importance of clinical cases of intoxication as involuntary toxicological trials for clinical pharmacology (author's transl)].
Topics: Biguanides; Clonidine; Digoxin; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceuti | 1978 |