biguanides and Acute Liver Injury, Drug-Induced studies

biguanides and Acute Liver Injury, Drug-Induced

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Research Excerpts

Excerpt	Relevance	Reference
" As an essential complication provoked by biguanides a lactic acidosis may be elicited which--though seldom occurring--then in most cases takes a fatal course."	3.67	[Drug-induced harm due to antidiabetics]. ( Verlohren, HJ, 1984)

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (75.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (12.50)	29.6817
2010's	1 (12.50)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

6 (75.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (12.50)

29.6817

2010's

1 (12.50)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Kawamori, R	2
RANDIG, K	1
Kanazawa, A	1
Verlohren, HJ	1
Paterson, KR	1
Paice, BJ	1
Lawson, DH	1
Chow, AY	1
Hirsch, GH	1
Buttar, HS	1
Ito, T	1
Gubergrits, AIa	1
Lesnichiĭ, AV	1
Shevchenko, IV	1

Studies

Kawamori, R

RANDIG, K

Kanazawa, A

Verlohren, HJ

Paterson, KR

Paice, BJ

Lawson, DH

Chow, AY

Hirsch, GH

Buttar, HS

Ito, T

Gubergrits, AIa

Lesnichiĭ, AV

Shevchenko, IV

Reviews

4 reviews available for biguanides and Acute Liver Injury, Drug-Induced

Article	Year
[Adverse effects of insulin sensitisers and biguanides]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Acidosis, Lactic; Animals; Biguanides; Capillary Permeability; Chemical and Drug Induced Liver Injur	2007
Undesired effects of biguanide therapy. Adverse drug reactions and acute poisoning reviews, 1984,Autumn, Volume: 3, Issue:3 Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Drug Interact	1984
[Oral antidiabetics]. Horumon to rinsho. Clinical endocrinology, 1972, Volume: 20, Issue:10 Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Gastrointesti	1972
[The effect of different hypoglycemic preparations on the state of the functions and morphology of the liver in diabetes mellitus]. Terapevticheskii arkhiv, 1971, Volume: 43, Issue:12 Topics: Adult; Aged; Biguanides; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Female; Humans;	1971

Article

Year

[Adverse effects of insulin sensitisers and biguanides].

Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

Topics: Acidosis, Lactic; Animals; Biguanides; Capillary Permeability; Chemical and Drug Induced Liver Injur

2007

Undesired effects of biguanide therapy.

Adverse drug reactions and acute poisoning reviews, 1984,Autumn, Volume: 3, Issue:3

Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Drug Interact

1984

[Oral antidiabetics].

Horumon to rinsho. Clinical endocrinology, 1972, Volume: 20, Issue:10

Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Gastrointesti

1972

[The effect of different hypoglycemic preparations on the state of the functions and morphology of the liver in diabetes mellitus].

Terapevticheskii arkhiv, 1971, Volume: 43, Issue:12

Topics: Adult; Aged; Biguanides; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Female; Humans;

1971

Other Studies

4 other studies available for biguanides and Acute Liver Injury, Drug-Induced

Article	Year
[Biguanide, pioglitazone and alpha-glucosidase inhibitors]. Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6 Topics: Acidosis, Lactic; Biguanides; Body Weight; Chemical and Drug Induced Liver Injury; Digestive System;	2012
[DIABETES MELLITUS AND THE LIVER]. Deutsches medizinisches Journal, 1965, Feb-20, Volume: 16 Topics: Alcoholism; Biguanides; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Drug Therapy; Fat	1965
[Drug-induced harm due to antidiabetics]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Jan-01, Volume: 39, Issue:1 Topics: Abnormalities, Drug-Induced; Acidosis; Biguanides; Bone Marrow; Cardiovascular Diseases; Chemical an	1984
Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats. Toxicology and applied pharmacology, 1977, Volume: 42, Issue:1 Topics: Age Factors; Animals; Biguanides; Chemical and Drug Induced Liver Injury; Chlorhexidine; Female; Kid	1977

Article

Year

[Biguanide, pioglitazone and alpha-glucosidase inhibitors].

Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

Topics: Acidosis, Lactic; Biguanides; Body Weight; Chemical and Drug Induced Liver Injury; Digestive System;

2012

[DIABETES MELLITUS AND THE LIVER].

Deutsches medizinisches Journal, 1965, Feb-20, Volume: 16

Topics: Alcoholism; Biguanides; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Drug Therapy; Fat

1965

[Drug-induced harm due to antidiabetics].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Jan-01, Volume: 39, Issue:1

Topics: Abnormalities, Drug-Induced; Acidosis; Biguanides; Bone Marrow; Cardiovascular Diseases; Chemical an

1984

Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats.

Toxicology and applied pharmacology, 1977, Volume: 42, Issue:1

Topics: Age Factors; Animals; Biguanides; Chemical and Drug Induced Liver Injury; Chlorhexidine; Female; Kid

1977