biguanides has been researched along with Acidosis, Lactic in 23 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The keywords were: lactic acidosis, metformin, biguanide, diabetes mellitus." | 8.83 | [Metformin-associated lactic acidosis]. ( Chatti, O; Ghaddab, A; Ichai, C; Orban, JC, 2006) |
| " The danger of lactic acidosis can be avoided with the use of metformin, the less toxic of biguanides, and strict respect for contraindications." | 8.77 | [Biguanides in the treatment of diabetes mellitus]. ( Saraiva, AM, 1989) |
| " We herein report a case of cardiac dysfunction due to thiamine deficiency after hemodialysis in a patient with suspected biguanide-related lactic acidosis." | 8.12 | Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis. ( Jimura, F; Kachi, N; Tamaki, H; Tsushima, H, 2022) |
| " We herein present a case of biguanide-associated severe lactic acidosis complicated with thiamine deficiency that was provoked without predisposing factors for thiamine deficiency." | 7.85 | The Dramatic Recovery of a Patient with Biguanide-associated Severe Lactic Acidosis Following Thiamine Supplementation. ( Fujita, M; Godo, S; Kudo, D; Kushimoto, S; Nomura, R; Shimokawa, H; Yoshida, Y, 2017) |
| "A French analysis of reports of adverse effects shows that lactic acidosis due to metformin is preventable." | 7.74 | Metformin: preventable lactic acidosis. ( , 2007) |
| "Biguanides are a class of drugs widely used as oral antihyperglycemic agents for the treatment of type 2 diabetes mellitus, but they are associated with lactic acidosis, a lethal side effect." | 7.72 | Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin. ( Jonker, JW; Kato, Y; Kusuhara, H; Schinkel, AH; Sugiyama, Y; Wang, DS, 2003) |
| "We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 7.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
| " The keywords were: lactic acidosis, metformin, biguanide, diabetes mellitus." | 4.83 | [Metformin-associated lactic acidosis]. ( Chatti, O; Ghaddab, A; Ichai, C; Orban, JC, 2006) |
| " The danger of lactic acidosis can be avoided with the use of metformin, the less toxic of biguanides, and strict respect for contraindications." | 4.77 | [Biguanides in the treatment of diabetes mellitus]. ( Saraiva, AM, 1989) |
| " We herein report a case of cardiac dysfunction due to thiamine deficiency after hemodialysis in a patient with suspected biguanide-related lactic acidosis." | 4.12 | Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis. ( Jimura, F; Kachi, N; Tamaki, H; Tsushima, H, 2022) |
| " We herein present a case of biguanide-associated severe lactic acidosis complicated with thiamine deficiency that was provoked without predisposing factors for thiamine deficiency." | 3.85 | The Dramatic Recovery of a Patient with Biguanide-associated Severe Lactic Acidosis Following Thiamine Supplementation. ( Fujita, M; Godo, S; Kudo, D; Kushimoto, S; Nomura, R; Shimokawa, H; Yoshida, Y, 2017) |
| "A French analysis of reports of adverse effects shows that lactic acidosis due to metformin is preventable." | 3.74 | Metformin: preventable lactic acidosis. ( , 2007) |
| "Biguanides are a class of drugs widely used as oral antihyperglycemic agents for the treatment of type 2 diabetes mellitus, but they are associated with lactic acidosis, a lethal side effect." | 3.72 | Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin. ( Jonker, JW; Kato, Y; Kusuhara, H; Schinkel, AH; Sugiyama, Y; Wang, DS, 2003) |
| "We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 3.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
| "Drugs used to treat lactic acidosis can aggravate the condition." | 2.41 | Lactic acidosis update for critical care clinicians. ( Luft, FC, 2001) |
| "The biguanides are a class of oral hypoglycemic agents that are commonly used in the treatment of diabetes mellitus." | 2.38 | Biguanide-associated lactic acidosis. Case report and review of the literature. ( Arieff, AI; Barr, J; Gan, SC; Pearl, RG, 1992) |
| "No metformin related cases were found." | 1.28 | Biguanide related lactic acidosis: incidence and risk factors. ( Aguilar, C; García, JE; Reza, A; Rull, JA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Tamaki, H | 1 |
| Tsushima, H | 1 |
| Kachi, N | 1 |
| Jimura, F | 1 |
| Mohri, T | 1 |
| Okamoto, S | 1 |
| Nishioka, Y | 1 |
| Myojin, T | 1 |
| Kubo, S | 1 |
| Higashino, T | 1 |
| Okada, S | 1 |
| Akai, Y | 1 |
| Noda, T | 1 |
| Ishii, H | 1 |
| Imamura, T | 1 |
| Hotta, N | 1 |
| Godo, S | 1 |
| Yoshida, Y | 1 |
| Fujita, M | 1 |
| Kudo, D | 1 |
| Nomura, R | 1 |
| Shimokawa, H | 1 |
| Kushimoto, S | 1 |
| Levy, B | 1 |
| Perez, P | 1 |
| Perny, J | 1 |
| Kawamori, R | 2 |
| Yamasaki, Y | 1 |
| Kuroda, A | 1 |
| Wang, DS | 1 |
| Kusuhara, H | 1 |
| Kato, Y | 1 |
| Jonker, JW | 1 |
| Schinkel, AH | 1 |
| Sugiyama, Y | 1 |
| Ichai, C | 2 |
| Levraut, J | 1 |
| Samat-Long, C | 1 |
| Grimaud, D | 1 |
| Orban, JC | 1 |
| Ghaddab, A | 1 |
| Chatti, O | 1 |
| Yamagata, K | 1 |
| Andou, J | 1 |
| Amiya, E | 1 |
| Eguchi, K | 1 |
| Hatano, M | 1 |
| Hosoya, Y | 1 |
| Sibagaki, Y | 1 |
| Morita, T | 1 |
| Nagai, R | 1 |
| Kanazawa, A | 1 |
| Safadi, R | 1 |
| Yossepowitch, O | 1 |
| Ben-Yehuda, A | 1 |
| Rojas Hidalgo, E | 1 |
| Preiser, JC | 1 |
| Vincent, JL | 1 |
| Luft, FC | 1 |
| Aguilar, C | 1 |
| Reza, A | 1 |
| García, JE | 1 |
| Rull, JA | 1 |
| Gan, SC | 1 |
| Barr, J | 1 |
| Arieff, AI | 1 |
| Pearl, RG | 1 |
| Vambera, M | 1 |
| Cízková, M | 1 |
| Petr, P | 1 |
| Huidobro, F | 1 |
| Videla, C | 1 |
| Hernández, G | 1 |
| Torres, H | 1 |
| Jimenez, R | 1 |
| Pérez, H | 1 |
| Díaz, RA | 1 |
| Saraiva, AM | 1 |
| Ryder, RE | 1 |
9 reviews available for biguanides and Acidosis, Lactic
| Article | Year |
|---|---|
[Adverse effect of biguanides].
Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus, Type 2; Gastrointestinal Diseases; Humans; Hypoglyc | 2002 |
[Metformin-associated lactic acidosis].
Topics: Acidosis, Lactic; Biguanides; Humans; Hypoglycemic Agents; Metformin | 2006 |
[Adverse effects of insulin sensitisers and biguanides].
Topics: Acidosis, Lactic; Animals; Biguanides; Capillary Permeability; Chemical and Drug Induced Liver Injur | 2007 |
[Lactic acidosis associated with biguanides].
Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus; Humans; Hypoglycemic Agents | 1996 |
[Antidiabetic biguanides and lactic acidosis].
Topics: Acidosis, Lactic; Biguanides; Buformin; Diabetes Mellitus; Humans; Hypoglycemic Agents; Models, Biol | 1997 |
Lactic acidosis update for critical care clinicians.
Topics: Acidosis, Lactic; Biguanides; Critical Care; Diabetes Mellitus, Type 2; Humans | 2001 |
Biguanide-associated lactic acidosis. Case report and review of the literature.
Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Emigration and Immi | 1992 |
[Biguanides in the treatment of diabetes mellitus].
Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus; Humans; Lipid Metabolism; Metformin | 1989 |
The danger of high dose sodium bicarbonate in biguanide-induced lactic acidosis: the theory, the practice and alternative therapies.
Topics: Acidosis, Lactic; Bicarbonates; Biguanides; Humans; Sodium; Sodium Bicarbonate | 1987 |
14 other studies available for biguanides and Acidosis, Lactic
| Article | Year |
|---|---|
Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis.
Topics: Acidosis, Lactic; Beriberi; Biguanides; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hypoglyce | 2022 |
Risk of Lactic Acidosis in Hospitalized Diabetic Patients Prescribed Biguanides in Japan: A Retrospective Total-Population Cohort Study.
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Biguanides; Cohort Studies; Diabetes Mellitus; Female; Hu | 2023 |
A new perspective on the biguanide, metformin therapy in type 2 diabetes and lactic acidosis.
Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Pro | 2019 |
The Dramatic Recovery of a Patient with Biguanide-associated Severe Lactic Acidosis Following Thiamine Supplementation.
Topics: Acidosis, Lactic; Aged; Biguanides; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Humans; | 2017 |
Where does the lactate come from? A rare cause of reversible inhibition of mitochondrial respiration.
Topics: Acidosis, Lactic; Biguanides; Cell Respiration; Humans; Mitochondria | 2010 |
[Biguanide, pioglitazone and alpha-glucosidase inhibitors].
Topics: Acidosis, Lactic; Biguanides; Body Weight; Chemical and Drug Induced Liver Injury; Digestive System; | 2012 |
Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin.
Topics: Acidosis, Lactic; Animals; Biguanides; Disease Models, Animal; DNA-Binding Proteins; Hepatocytes; Ho | 2003 |
[Lactic acidosis and biguanides: coincidence or negligence of prescribing guidelines].
Topics: Acidosis, Lactic; Biguanides; Drug Prescriptions; Guidelines as Topic; Hypoglycemic Agents; Metformi | 2003 |
[A persistent shock state with severe lactic acidosis, after increasing biguanaide to a diabetic patient with renal impairment].
Topics: Acidosis, Lactic; Aged; Biguanides; Diabetes Mellitus; Diabetic Nephropathies; Humans; Male; Shock | 2006 |
Metformin: preventable lactic acidosis.
Topics: Acidosis, Lactic; Biguanides; Diabetes Mellitus, Type 2; Female; France; Humans; Male; Metformin | 2007 |
Specific therapies of biguanide-induced lactic acidosis.
Topics: Acidosis, Lactic; Biguanides; Dichloroacetic Acid; Humans | 1998 |
Biguanide related lactic acidosis: incidence and risk factors.
Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Contraindications; Diabete | 1992 |
[Lactic acidosis as a complication of treatment with biguanides].
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Biguanides; Female; Humans | 1990 |
[Lactic acidosis in diabetic patients associated with buformin].
Topics: Acidosis, Lactic; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Diabetic Angiopathies | 1989 |