biflorin and Neoplasms

biflorin has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for biflorin and Neoplasms

Article	Year
Synthesis, antibacterial and cytotoxic activities of new biflorin-based hydrazones and oximes. Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2 Biflorin 1 is a biologically active quinone, isolated from Capraria biflora. Five new biflorin-based nitrogen derivatives were synthesized, of which two were mixtures of (E)- and (Z)- isomers: (Z)-2a, (Z)-2b, (Z)-3a, (Z)- and (E)-3b, (Z)- and (E)-3c. The antibacterial activity was investigated using the microdilution method for determining the minimum inhibitory concentration (MIC) against six bacterial strains. Tests have shown that these derivatives have potential against all bacterial strains. The cytotoxic activity was also evaluated against three strains of cancer cells, but none of the derivatives showed activity. Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Bacteria; Bacterial Infections; Cell Line, Tumor; Humans; Hydrazones; Microbial Sensitivity Tests; Naphthoquinones; Neoplasms; Oximes; Scrophulariaceae	2016

Article

Year

Synthesis, antibacterial and cytotoxic activities of new biflorin-based hydrazones and oximes.

Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

Biflorin 1 is a biologically active quinone, isolated from Capraria biflora. Five new biflorin-based nitrogen derivatives were synthesized, of which two were mixtures of (E)- and (Z)- isomers: (Z)-2a, (Z)-2b, (Z)-3a, (Z)- and (E)-3b, (Z)- and (E)-3c. The antibacterial activity was investigated using the microdilution method for determining the minimum inhibitory concentration (MIC) against six bacterial strains. Tests have shown that these derivatives have potential against all bacterial strains. The cytotoxic activity was also evaluated against three strains of cancer cells, but none of the derivatives showed activity.

Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Bacteria; Bacterial Infections; Cell Line, Tumor; Humans; Hydrazones; Microbial Sensitivity Tests; Naphthoquinones; Neoplasms; Oximes; Scrophulariaceae

2016