biflorin has been researched along with Neoplasms* in 1 studies
1 other study(ies) available for biflorin and Neoplasms
Article | Year |
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Synthesis, antibacterial and cytotoxic activities of new biflorin-based hydrazones and oximes.
Biflorin 1 is a biologically active quinone, isolated from Capraria biflora. Five new biflorin-based nitrogen derivatives were synthesized, of which two were mixtures of (E)- and (Z)- isomers: (Z)-2a, (Z)-2b, (Z)-3a, (Z)- and (E)-3b, (Z)- and (E)-3c. The antibacterial activity was investigated using the microdilution method for determining the minimum inhibitory concentration (MIC) against six bacterial strains. Tests have shown that these derivatives have potential against all bacterial strains. The cytotoxic activity was also evaluated against three strains of cancer cells, but none of the derivatives showed activity. Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Bacteria; Bacterial Infections; Cell Line, Tumor; Humans; Hydrazones; Microbial Sensitivity Tests; Naphthoquinones; Neoplasms; Oximes; Scrophulariaceae | 2016 |