bifendate has been researched along with Acute Liver Injury, Drug-Induced in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cen, J; Fang, D; Guo, H; Hong, C; Luo, W; Lv, J; Wang, C; Wang, T; Yang, Y | 1 |
| Abudureyimu, M; Liu, G; Maitinuer, Y; Saimaiti, R; Talifu, A; Xin, X | 1 |
| Li, HL; Wang, YH; Xu, XJ | 1 |
| Duan, JA; Fang, T; Shen, X; Tang, Y; Yang, R; Yu, L | 1 |
| Hong, Z; Hu, J; Li, T; Lin, J; Zhao, J; Zhou, J | 1 |
| Ding, G; Fu, Z; Guo, W; Li, R; Wang, Z; Zou, Y | 1 |
| Cui, Y; Liu, J; Wang, J; Zhang, B; Zhang, Y | 1 |
| Doan, V; Huang, J; Huang, R; Huang, Y; Lin, X; Nguyen, V; Tang, A; Tang, X; Yang, X | 1 |
| El-Laithy, HM | 1 |
| Dai, C; Hao, H; Kang, A; Li, J; Liang, Y; Sun, S; Wang, G; Xie, L; Xie, T; Xie, Y; Zheng, X | 1 |
| Abdelbary, GA; Aburahma, MH | 1 |
| Li, Y; Lu, H | 1 |
| Li, Y | 1 |
| Bae, EA; Choo, MK; Kim, DH; Lee, HW | 1 |
| el-Bahrawy, HA; el-Sawy, SA; el-Shafey, AM | 1 |
| Gao, M; Liu, G; Zhang, J | 1 |
| Abdel-Hameid, NA | 1 |
| Chung, HC; Hong, SY; Jung, KH; Kim, SG; Nam, SY | 1 |
| Ham, KS; Kim, SK; Kim, SN; Kim, SY; Kim, YC; Lee, WY; Yim, HK; Yoon, MY | 1 |
| Che, CT; Ip, SP; Ko, KM | 1 |
| Fu, T; Liu, G | 1 |
| Shi, JZ; Yang, XY; Yu, HQ; Zhang, YX | 1 |
| Ben, CE; Wang, GX; Ye, BK | 1 |
23 other study(ies) available for bifendate and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Development of tacrine-bifendate conjugates with improved cholinesterase inhibitory and pro-cognitive efficacy and reduced hepatotoxicity.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Biphenyl Compounds; Cell Line; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Cholinesterases; Cognition; Drug Design; Hep G2 Cells; Humans; Liver; Male; Mice, Inbred ICR; PC12 Cells; Rats; Tacrine | 2018 |
Multiomics analysis profile acute liver injury module clusters to compare the therapeutic efficacy of bifendate and muaddil sapra.
Topics: Biphenyl Compounds; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Humans; Metabolome; Transcriptome | 2019 |
Hepatoprotective effects of Mimic of Manganese superoxide dismutase against carbon tetrachloride-induced hepatic injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomimetic Materials; Biphenyl Compounds; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Glutathione Peroxidase; Heterocyclic Compounds, 4 or More Rings; Inflammation Mediators; Interleukin-6; Liver; Male; Malondialdehyde; Mice; Mice, Inbred Strains; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biphenyl Compounds; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Fruit; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Protective Agents; Superoxide Dismutase; Ziziphus | 2009 |
Hepatoprotection in a rat model of acute liver damage through inhibition of CY2E1 activity by total alkaloids extracted from Rubus alceifolius Poir.
Topics: Alkaloids; Animals; Biomarkers; Biphenyl Compounds; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Female; Male; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosaceae | 2011 |
Hepatoprotective action of Radix Paeoniae Rubra aqueous extract against CCl4-induced hepatic damage.
Topics: Animals; Antioxidants; Biphenyl Compounds; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Oxidative Stress; Paeonia; Phytotherapy; Plant Roots; Protective Agents; Rats; Rats, Wistar | 2011 |
Protective effect of Lysimachia christinae against acute alcohol-induced liver injury in mice.
Topics: Animals; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Ethanol; Male; Mice; Oxidative Stress; Plant Extracts; Primulaceae; Quercetin | 2012 |
Hepatoprotective effects of Yulangsan polysaccharide against nimesulide-induced liver injury in mice.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dioxoles; Down-Regulation; Female; Inflammation Mediators; Male; Malondialdehyde; Medicine, Chinese Traditional; Mice; Millettia; Oxidative Stress; Polysaccharides; Sulfonamides; Up-Regulation | 2015 |
Self-nanoemulsifying drug delivery system for enhanced bioavailability and improved hepatoprotective activity of biphenyl dimethyl dicarboxylate.
Topics: Animals; Biological Availability; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dioxoles; Drug Delivery Systems; Emulsions; Excipients; Liver; Liver Function Tests; Nanoparticles; Oils; Oxidative Stress; Particle Size; Protective Agents; Rats; Surface-Active Agents | 2008 |
Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers.
Topics: Alanine Transaminase; Animals; Area Under Curve; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Dioxoles; Disease Models, Animal; Down-Regulation; Female; Fruit; Herb-Drug Interactions; Lignans; Male; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Reference Values; Schisandra | 2010 |
Novel diphenyl dimethyl bicarboxylate provesicular powders with enhanced hepatocurative activity: preparation, optimization, in vitro/in vivo evaluation.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Calorimetry, Differential Scanning; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Dioxoles; Disease Models, Animal; Drug Compounding; Liposomes; Liver; Male; Microscopy, Electron, Transmission; Particle Size; Polysorbates; Powder Diffraction; Powders; Rats; Rats, Wistar; Rheology; Solubility; Sorbitol; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Time Factors; Water; X-Ray Diffraction | 2012 |
Effects of dimethyl diphenyl bicarboxylate on the metabolism and hepatotoxicity of aflatoxin B1 in rats.
Topics: Aflatoxin B1; Aflatoxin M1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dioxoles; Disease Models, Animal; Male; Microsomes, Liver; Protective Agents; Rats | 2002 |
[Effect of dimethyl diphenyl bicarboxylate (DDB) on 9-amino-1,2,3,4-tetrahydroacridine-induced hepatotoxicity in mice].
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; Dioxoles; Disease Models, Animal; Male; Mice; Microsomes, Liver; Protective Agents; Random Allocation; Rats; Rats, Wistar; Tacrine | 2001 |
Beta-glucuronidase inhibitor tectorigenin isolated from the flower of Pueraria thunbergiana protects carbon tetrachloride-induced liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dioxoles; Disulfides; Drugs, Chinese Herbal; Enzyme Inhibitors; Flowers; Glucuronidase; Injections, Intraperitoneal; Isoflavones; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Phytotherapy; Plant Extracts; Pueraria | 2003 |
Effect of dimethyl diphenyl bicarboxylate on normal and chemically-injured liver.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Dioxoles; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Liver Diseases; Liver Function Tests; Male; Malondialdehyde; Rats; Time Factors | 2002 |
Effect of diphenyl dimethyl bicarboxylate on concanavalin A-induced liver injury in mice.
Topics: Adjuvants, Immunologic; Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Dioxoles; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gene Expression; Hepatitis, Animal; Hepatocytes; Liver; Liver Function Tests; Male; Mice; Mice, Inbred ICR; Protective Agents; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Protective role of dimethyl diphenyl bicarboxylate (DDB) against erythromycin induced hepatotoxicity in male rats.
Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Bilirubin; Body Weight; Chemical and Drug Induced Liver Injury; Cholesterol; Dioxoles; Erythromycin; Hepatocytes; Liver; Male; Necrosis; Organ Size; Rats; Spleen | 2007 |
Enhanced effectiveness of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in combination with garlic oil against experimental hepatic injury in rats and mice.
Topics: 1-Propanol; Administration, Oral; Allyl Compounds; Animals; Antioxidants; Carbon Tetrachloride; Cell Death; Chemical and Drug Induced Liver Injury; Cholesterol; Dioxoles; Drug Synergism; Drugs, Chinese Herbal; Kupffer Cells; Liver; Liver Diseases; Male; Mice; Propanols; Rats; Rats, Sprague-Dawley; Sulfides; Transaminases; Triglycerides | 1995 |
Effect of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'- dicarboxylate (DDB) on chemical-induced liver injury.
Topics: Acetaminophen; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dioxoles; Drugs, Chinese Herbal; Ethanol; Fatty Liver, Alcoholic; Female; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley | 1999 |
Structure-activity relationship of schisandrins in enhancing liver mitochondrial glutathione status in CCl4-poisoned mice.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Female; Glutathione; Glutathione Reductase; Lignans; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Polycyclic Compounds; Structure-Activity Relationship | 1998 |
[Protective effects of biphenyl dimethyl dicarboxylate on damage in isolated rat hepatocytes induced by carbon tetrachloride and D-galactosamine].
Topics: Animals; Carbon Tetrachloride Poisoning; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dioxoles; Galactosamine; Liver; Male; Mice; Rats; Rats, Inbred Strains; Ribosomal Proteins; RNA | 1990 |
Biphenyl-dimethyl dicarboxylate in treating and preventing hepatitis due to drug poisoning.
Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Choriocarcinoma; Dioxoles; Female; Humans; Pregnancy; Uterine Neoplasms | 1987 |
[Reparative effects of biphenyl dimethyl dicarboxylate on experimental liver injury in rats with histochemical and electronmicroscopy study].
Topics: Animals; Chemical and Drug Induced Liver Injury; Dioxoles; Histocytochemistry; Liver; Liver Regeneration; Male; Rats | 1988 |