bifemelane and Brain Ischemia

bifemelane has been researched along with Brain Ischemia in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's11 (64.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujishima, M; Ishitsuka, T; Omae, T1
Egawa, M; Mitsuka, M; Tobe, A; Umezu, K1
Hata, R; Kamada, T; Kitagawa, K; Matsumoto, M; Matsuyama, T; Sugita, M; Tagaya, M1
Nakamura, T; Ohkawa, I; Ozaki, S; Tajima, T1
Arai, Y; Gu, GZ; Matsumoto, K; Mizushima, H; Nakai, Y; Shimazu, M; Shioda, S1
Asanuma, M; Chou, HH; Hirata, H; Kondo, Y; Mori, A; Ogawa, N1
Kanazawa, A; Kondo, T1
Kitagawa, K; Kuwabara, K; Mabuchi, T; Matsumoto, M; Matsushita, K; Ohtsuki, T; Taguchi, A; Yanagihara, T; Yang, GM1
Asanuma, M; Iwata, E; Kondo, Y; Matsuura, K; Nishibayashi, K; Ogawa, N1
Egashira, T; Takayama, F; Yamanaka, Y1
Matsumoto, M; Mori, K; Saito, H; Suda, N; Togashi, H; Yoshioka, M1
Asanuma, M; Haba, K; Hirata, H; Mori, A; Ogawa, N1
Izuta, M; Kanashiro, M; Maruki, Y; Naritomi, H; Sasaki, M; Sawada, T1
Haba, K; Mizukawa, K; Ogawa, N; Ono, T; Yoshikawa, H1
Goto, Y; Kikuchi, H; Taki, W1
Egawa, M; Hashimoto, N; Tobe, A1
Honda, S; Saito, K; Tobe, A; Yanagiya, I1

Other Studies

17 other study(ies) available for bifemelane and Brain Ischemia

ArticleYear
[Protective effects of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (bifemelane) on acutely induced cerebral ischemia in Mongolian gerbils and spontaneously hypertensive rats (SHR)].
    No to shinkei = Brain and nerve, 1984, Volume: 36, Issue:10

    Topics: Animals; Benzhydryl Compounds; Brain; Brain Ischemia; Disease Models, Animal; Female; Gerbillinae; Glucose; Male; Rats; Rats, Inbred SHR; Time Factors

1984
Effects of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016) on survival time and brain monoamine levels in bilaterally carotid-artery-ligated gerbils.
    Japanese journal of pharmacology, 1984, Volume: 34, Issue:3

    Topics: Animals; Arterial Occlusive Diseases; Benzhydryl Compounds; Biogenic Amines; Brain Chemistry; Brain Ischemia; Carotid Artery Diseases; Gerbillinae; Ligation; Male; Norepinephrine; Serotonin

1984
Therapeutic effect of bifemelane on unilateral cerebral ischemia in gerbils.
    Life sciences, 1995, Volume: 57, Issue:4

    Topics: Animals; Benzhydryl Compounds; Brain Chemistry; Brain Ischemia; Female; Gerbillinae; Male; Microtubule-Associated Proteins

1995
[Effect of bifemelane hydrochloride in rats on the improvement of the learning and memory impairments and prevention of neuronal damage following transient forebrain ischemia].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1994, Volume: 104, Issue:6

    Topics: Animals; Avoidance Learning; Benzhydryl Compounds; Brain Ischemia; Dose-Response Relationship, Drug; Male; Memory; Rats; Rats, Wistar

1994
Protective effect of bifemelane on c-Fos-like immunoreactivity in rat cerebral ischemia.
    Brain research bulletin, 1994, Volume: 34, Issue:3

    Topics: Animals; Benzhydryl Compounds; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Immunohistochemistry; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar

1994
Ischemia-induced changes in alpha-tubulin and beta-actin mRNA in the gerbil brain and effects of bifemelane hydrochloride.
    Brain research, 1993, Jan-15, Volume: 600, Issue:2

    Topics: Actins; Animals; Antidepressive Agents; Benzhydryl Compounds; Blotting, Northern; Brain Chemistry; Brain Ischemia; Gerbillinae; Histocytochemistry; In Situ Hybridization; RNA Probes; RNA, Messenger; Sulfur Radioisotopes; Tubulin

1993
[Hydroxyl radical generation and post-ischemic reperfusion brain damage implications for neuroprotection].
    No to shinkei = Brain and nerve, 1996, Volume: 48, Issue:6

    Topics: Animals; Benzhydryl Compounds; Brain Ischemia; Cell Survival; Cerebral Cortex; Free Radical Scavengers; Gerbillinae; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Neurons; Reperfusion Injury; Salicylates; Salicylic Acid

1996
Bifemelane hydrochloride enhances 'ischemic tolerance' phenomenon in gerbil hippocampal CA1 neurons.
    Life sciences, 1996, Volume: 59, Issue:12

    Topics: Adaptation, Physiological; Animals; Benzhydryl Compounds; Brain Ischemia; Free Radical Scavengers; Gerbillinae; Hippocampus; Male; Neurons; Oxidative Stress

1996
Preventive effects of bifemelane hydrochloride on decreased levels of muscarinic acetylcholine receptor and its mRNA in a rat model of chronic cerebral hypoperfusion.
    Neuroscience research, 1996, Volume: 24, Issue:4

    Topics: Animals; Arterial Occlusive Diseases; Benzhydryl Compounds; Blotting, Northern; Brain Ischemia; Chronic Disease; Disease Models, Animal; Frontal Lobe; Gene Expression; Hippocampus; Male; Muscarinic Antagonists; Neostriatum; Nootropic Agents; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; RNA, Messenger; Tritium

1996
Effects of bifemelane on muscarinic receptors and choline acetyltransferase in the brains of aged rats following chronic cerebral hypoperfusion induced by permanent occlusion of bilateral carotid arteries.
    Japanese journal of pharmacology, 1996, Volume: 72, Issue:1

    Topics: Age Factors; Aging; Animals; Benzhydryl Compounds; Binding, Competitive; Brain Ischemia; Choline O-Acetyltransferase; Corpus Striatum; Hippocampus; Kinetics; Male; Muscarinic Antagonists; Nootropic Agents; Prefrontal Cortex; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic

1996
Effects of bifemelane on incomplete cerebral ischaemia-induced reduction of long-term potentiation in rat hippocampal neurones in vivo.
    Pharmacology & toxicology, 1999, Volume: 85, Issue:2

    Topics: Animals; Area Under Curve; Benzhydryl Compounds; Brain Ischemia; Carotid Arteries; Electrodes; Electrophysiology; Hippocampus; Long-Term Potentiation; Male; Neurons; Nootropic Agents; Perforant Pathway; Rats; Rats, Wistar; Synapses

1999
Comparison of the effects of bifemelane hydrochloride, idebenone and indeloxazine hydrochloride on ischemia-induced changes in brain monoamines and their metabolites in gerbils.
    Journal of neural transmission. General section, 1992, Volume: 88, Issue:3

    Topics: Animals; Benzhydryl Compounds; Benzoquinones; Biogenic Monoamines; Brain Chemistry; Brain Ischemia; Dopamine; Gerbillinae; Hydroxyindoleacetic Acid; Morpholines; Nerve Tissue Proteins; Norepinephrine; Serotonin; Ubiquinone

1992
Effect of bifemelane on the intracellular pH and energy state of the ischemic brain.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antidepressive Agents; Benzhydryl Compounds; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Ischemia; Carbon Dioxide; Energy Metabolism; Gerbillinae; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Oxygen; Phosphates; Phosphocreatine

1990
Comparison of the effects of bifemelane hydrochloride, idebenone and indeloxazine hydrochloride on ischemia-induced depletion of brain acetylcholine levels in gerbils.
    Research communications in chemical pathology and pharmacology, 1988, Volume: 61, Issue:2

    Topics: Acetylcholine; Animals; Benzhydryl Compounds; Benzoquinones; Brain Chemistry; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Gerbillinae; Hippocampus; Humans; Infant, Newborn; Morpholines; Quinones; Ubiquinone

1988
[Effects of bifemelane on the free fatty acid levels during ischemia].
    No to shinkei = Brain and nerve, 1988, Volume: 40, Issue:11

    Topics: Animals; Benzhydryl Compounds; Brain; Brain Ischemia; Cerebrovascular Circulation; Fatty Acids, Nonesterified; Rats; Rats, Inbred Strains

1988
[Effect of MCI-2016 (bifemelane hydrochloride) on cerebral ischemia following ligation of both common carotid arteries in Mongolian gerbils].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:6

    Topics: Administration, Oral; Age Factors; Animals; Benzhydryl Compounds; Brain Ischemia; Carotid Artery Diseases; Constriction, Pathologic; gamma-Aminobutyric Acid; Gerbillinae; Male; Pantothenic Acid; Piperidines

1985
Effects of bifemelane hydrochloride (MCI-2016) on acetylcholine level reduced by scopolamine, hypoxia and ischemia in the rats and mongolian gerbils.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:4

    Topics: Acetylcholine; Animals; Antidepressive Agents; Benzhydryl Compounds; Brain Ischemia; Cerebral Cortex; Gerbillinae; Hippocampus; Hypoxia; Male; Rats; Rats, Inbred Strains; Scopolamine; Time Factors

1985