bicuculline has been researched along with Neuralgia in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 15 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antunes, GF; Assis, DV; Auada, AVV; de Andrade, EM; Fonoff, ET; Gouveia, FV; Lebrun, I; Lopes, PSS; Martinez, RCR; Pagano, RL | 1 |
| Cheng, JK; Chiou, LC; Ho, YC | 1 |
| Cai, J; Fang, D; Jiang, H; Jin, ZR; Kang, XJ; Kong, LY; Wan, Y; Xing, GG | 1 |
| Jin, CY; Pertovaara, A; Viisanen, H; Wei, H; You, HJ | 1 |
| Chen, G; Grill, WM; Janik, JJ; Ji, RR; Peters, RV; Zhang, TC | 1 |
| Dong, X; Guan, Y; He, SQ; Raja, SN; Sdrulla, AD; Shechter, R; Shu, B; Tiwari, V; Wang, Y; Xu, Q; Yang, F; Zhang, C | 1 |
| Hu, ZY; Li, XL; Liu, X; Ma, Q; Wang, C; Zhao, X; Zhou, DS; Zhou, WH | 1 |
| Dias, QM; Prado, WA | 1 |
| Donahue, R; Jamal, AB; Kaushal, R; Ma, F; Taylor, BK; Westlund, KN; Zhang, L | 1 |
| Cho, CB; Lee, YJ; Moon, HC; Park, YS | 1 |
| Choi, JI; Huang, LJ; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Chung, JM; Chung, K; Kim, HK; Kim, HY; Lee, KY; Wang, J; Yowtak, J | 1 |
| Barchini, J; Jabbur, SJ; Linderoth, B; Meyerson, BA; Saadé, NE; Shamaa, F; Song, Z; Tchachaghian, S | 1 |
| Malmierca, E; Martin, YB; Nuñez, A | 1 |
| Eisenach, JC; Hayashida, K; Kimura, M; Obata, H; Saito, S | 1 |
| Covey, DF; Jevtovic-Todorovic, V; Pathirathna, S; Todorovic, SM | 1 |
| Han, JS; Liu, FY; Qu, XX; Wan, Y; Xing, GG | 1 |
| Jones, DL; Puig, S; Sorkin, LS | 1 |
18 other study(ies) available for bicuculline and Neuralgia
| Article | Year |
|---|---|
Neurochemical effects of motor cortex stimulation in the periaqueductal gray during neuropathic pain.
Topics: Analgesia; Animals; Bicuculline; Deep Brain Stimulation; Efferent Pathways; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hyperalgesia; Male; Microdialysis; Microinjections; Motor Cortex; Neuralgia; Pain Threshold; Periaqueductal Gray; Rats; Rats, Wistar; Sciatic Nerve; Sciatica; Strychnine | 2019 |
Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic pain.
Topics: Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Neuralgia; Neurons; Pain Measurement; Patch-Clamp Techniques; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Spinal Nerves; Synaptic Transmission; Tetrodotoxin | 2013 |
Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats.
Topics: Action Potentials; Animals; Anxiety; Apoptosis; Behavior, Animal; Bicuculline; Blotting, Western; Caspase 3; Cell Membrane; Central Amygdaloid Nucleus; GABAergic Neurons; Hyperalgesia; In Situ Nick-End Labeling; Ligation; Male; Muscimol; Neural Inhibition; Neuralgia; Rats, Sprague-Dawley; Spinal Nerves | 2014 |
Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzothiazoles; Bicuculline; GABA-A Receptor Antagonists; Histamine; Histamine H2 Antagonists; Hot Temperature; Hyperalgesia; Imidazoles; Indans; Locus Coeruleus; Male; Neuralgia; Phenoxypropanolamines; Physical Stimulation; Piperidines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Histamine; Spinal Nerves | 2014 |
Spinal sensory projection neuron responses to spinal cord stimulation are mediated by circuits beyond gate control.
Topics: Action Potentials; Animals; Bicuculline; Computer Simulation; Disease Models, Animal; GABA-A Receptor Antagonists; Lumbar Vertebrae; Male; Microelectrodes; Models, Neurological; Neural Inhibition; Neuralgia; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatic Nerve; Sensory Receptor Cells; Spinal Cord; Spinal Cord Stimulation | 2015 |
Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agents; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Green Fluorescent Proteins; Long-Term Synaptic Depression; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Fibers; Neuralgia; Posterior Horn Cells; Red Fluorescent Protein; Sensory Thresholds; Spinal Cord; Spinal Nerves; Vesicular Glutamate Transport Protein 2 | 2015 |
Antinociceptive effects of fisetin against diabetic neuropathic pain in mice: Engagement of antioxidant mechanisms and spinal GABAA receptors.
Topics: Analgesics; Animals; Antioxidants; Bicuculline; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Flavonoids; Flavonols; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Oxidative Stress; Reactive Oxygen Species; Receptors, GABA-A; Spinal Cord; Streptozocin | 2015 |
The lesion of dorsolateral funiculus changes the antiallodynic effect of the intrathecal muscimol and baclofen in distinct phases of neuropathic pain induced by spinal nerve ligation in rats.
Topics: Animals; Baclofen; Bicuculline; Functional Laterality; GABA Agents; Hyperalgesia; Injections, Spinal; Ligation; Male; Muscimol; Neuralgia; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord Dorsal Horn; Spinal Nerves; Statistics, Nonparametric | 2016 |
GABA-A receptor activity in the noradrenergic locus coeruleus drives trigeminal neuropathic pain in the rat; contribution of NAα1 receptors in the medial prefrontal cortex.
Topics: Activating Transcription Factor 3; Adrenergic alpha-Antagonists; Adrenergic Neurons; Animals; Bicuculline; Chronic Pain; Disease Models, Animal; Facial Pain; GABA-A Receptor Antagonists; Hyperalgesia; Idazoxan; Locus Coeruleus; Male; Neuralgia; Oxathiins; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Trigeminal Nerve Injuries | 2016 |
Suppressed GABAergic signaling in the zona incerta causes neuropathic pain in a thoracic hemisection spinal cord injury rat model.
Topics: Action Potentials; Animals; Bicuculline; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neuralgia; Neurons; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries; Zona Incerta | 2016 |
Effect of sildenafil on neuropathic pain and hemodynamics in rats.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Heart Rate; Hemodynamics; Male; Neuralgia; Pain Threshold; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Sildenafil Citrate; Sulfones | 2010 |
Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release.
Topics: Analysis of Variance; Animals; Bicuculline; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Free Radical Scavengers; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Male; Mice; Neuralgia; Neurons; Reactive Oxygen Species; Spinal Cord; Spinal Nerves; tert-Butylhydroperoxide; Time Factors | 2011 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; Bicuculline; Disease Models, Animal; Dopamine Antagonists; Electrodes; Female; GABA Antagonists; Hyperalgesia; Ketanserin; Methysergide; Neuralgia; Pain Measurement; Pain Threshold; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Sulpiride; Time Factors; Transcutaneous Electric Nerve Stimulation | 2012 |
Inhibitory control of nociceptive responses of trigeminal spinal nucleus cells by somatosensory corticofugal projection in rat.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Biophysics; Capsaicin; Constriction; Disease Models, Animal; Electric Stimulation; Female; GABA-A Receptor Antagonists; Glutamic Acid; Glycine Agents; Hyperalgesia; Iontophoresis; Male; Neural Inhibition; Neuralgia; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Strychnine; Time Factors; Trigeminal Nucleus, Spinal | 2012 |
Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-aminobutyric acid mechanisms.
Topics: Animals; Atropine; Bicuculline; Cholinergic Agents; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; GABA Agents; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Indans; Male; Mecamylamine; Neuralgia; Nicotinic Antagonists; Organophosphorus Compounds; Parasympatholytics; Peripheral Nerve Injuries; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2013 |
5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain.
Topics: Anesthetics; Animals; Behavior, Animal; Bicuculline; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Estranes; Female; GABA Antagonists; Hot Temperature; Hyperalgesia; Neuralgia; Nitriles; Oxidation-Reduction; Pain Measurement; Pain Threshold; Pregnanediones; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Steroids; Time Factors; Touch; Treatment Outcome | 2005 |
Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain.
Topics: Action Potentials; Animals; Bicuculline; Dizocilpine Maleate; Drug Combinations; Electroacupuncture; Excitatory Amino Acid Antagonists; GABA Antagonists; Hyperesthesia; Ligation; Long-Term Synaptic Depression; Male; Methysergide; Naloxone; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Neuralgia; Neuronal Plasticity; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Nerves; Synapses; Time Factors | 2007 |
Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Cats; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Microdialysis; Neuralgia; Neurons, Afferent; Nociceptors; Pain Threshold; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stimulation, Chemical; Strychnine | 1998 |