Page last updated: 2024-08-21

bicuculline and Nerve Degeneration

bicuculline has been researched along with Nerve Degeneration in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's3 (16.67)18.2507
2000's4 (22.22)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ramírez-Jarquín, UN; Tapia, R1
Bear, CE; Bennett, SA; Cortez, MA; D'Antonio, C; Dhani, SU; Huan, LJ; Li, C; Snead, OC; Whitehead, SN1
Cantero, G; Fernández-Chacón, R; García-Junco-Clemente, P; Gómez-Sánchez, L; Linares-Clemente, P; Luján, R; Martínez-López, JA1
Green, CR; Nicholson, LF; O'Carroll, SJ; Yoon, JJ1
Abercrombie, ED; Callahan, JW; Farrar, AM1
Canonaco, M; Crudo, M; Facciolo, RM; Giusi, G; Zizza, M1
Aoyama, K; Chan, WY; Chen, Y; Hamby, AM; Liu, J; Suh, SW; Swanson, RA1
Sañudo-Peña, MC; Walker, JM1
Celada, P; Paladini, CA; Tepper, JM1
Conti, M; De Luigi, A; De Simoni, MG; Marchesi, F; Moneta, D; Ravizza, T; Vezzani, A1
Carlen, PL; Frantseva, MV; Hwang, PA; Velazquez, JL1
Lukasiuk, K; Pitkänen, A1
Leung, LS; Wu, K1
Clifford, DB; Olney, JW; Zorumski, CF1
Sakai, A; Sugimoto, T; Takemura, M1
Ishimaru, M; Sakai, A; Sugimoto, T; Takemura, M1
Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV; Okazaki, MM1
Okubo, J; Sakai, A; Sugimoto, T; Takemura, M1

Other Studies

18 other study(ies) available for bicuculline and Nerve Degeneration

ArticleYear
Chronic GABAergic blockade in the spinal cord in vivo induces motor alterations and neurodegeneration.
    Neuropharmacology, 2017, 05-01, Volume: 117

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Bicuculline; Dizocilpine Maleate; Drug Interactions; GABA Antagonists; Gait; Male; Motor Activity; Motor Neurons; Muscle Hypotonia; Nerve Degeneration; Rats; Receptors, Glycine; Spinal Cord; Strychnine

2017
Disruption of ClC-2 expression is associated with progressive neurodegeneration in aging mice.
    Neuroscience, 2010, Apr-28, Volume: 167, Issue:1

    Topics: Aging; Animals; Astrocytes; Bicuculline; CA3 Region, Hippocampal; Cell Death; Chloride Channels; CLC-2 Chloride Channels; Electroencephalography; GABA Antagonists; Hippocampus; Immunoblotting; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Picrotoxin

2010
Cysteine string protein-alpha prevents activity-dependent degeneration in GABAergic synapses.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, May-26, Volume: 30, Issue:21

    Topics: Age Factors; Animals; Animals, Newborn; Astrocytes; Bicuculline; Cells, Cultured; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; HSP40 Heat-Shock Proteins; Inhibitory Postsynaptic Potentials; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Confocal; Microscopy, Electron, Transmission; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Synapses

2010
Dose-dependent protective effect of connexin43 mimetic peptide against neurodegeneration in an ex vivo model of epileptiform lesion.
    Epilepsy research, 2010, Volume: 92, Issue:2-3

    Topics: Animals; Animals, Newborn; Bicuculline; CA1 Region, Hippocampal; Cell Death; Connexin 43; Culture Media, Serum-Free; Dose-Response Relationship, Drug; GABA Antagonists; In Vitro Techniques; Microtubule-Associated Proteins; Nerve Degeneration; Peptides; Rats; Rats, Wistar; Time Factors

2010
Reduced striatal acetylcholine efflux in the R6/2 mouse model of Huntington's disease: an examination of the role of altered inhibitory and excitatory mechanisms.
    Experimental neurology, 2011, Volume: 232, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Bicuculline; Cholinergic Neurons; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Humans; Huntingtin Protein; Huntington Disease; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Transgenic; Motor Skills; Nerve Degeneration; Nerve Tissue Proteins; Neural Inhibition; Nuclear Proteins; Synaptic Transmission

2011
Lead-induced neurodegenerative events and abnormal behaviors occur via ORXRergic/GABA(A)Rergic mechanisms in a marine teleost.
    Aquatic toxicology (Amsterdam, Netherlands), 2013, Jan-15, Volume: 126

    Topics: Animals; Behavior, Animal; Bicuculline; Brain; Feeding Behavior; GABA-A Receptor Antagonists; Gene Expression Regulation; Lead; Muscimol; Nerve Degeneration; Nitrates; Orexin Receptors; Perciformes; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Swimming

2013
Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.
    Nature neuroscience, 2006, Volume: 9, Issue:1

    Topics: Acetylcysteine; Aging; Animals; Behavior, Animal; Bicuculline; Blotting, Western; Brain; Cysteine; Excitatory Amino Acid Transporter 3; GABA Antagonists; Genotype; Glutathione; Immunohistochemistry; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Oxidants; Oxidative Stress

2006
A novel neurotransmitter system involved in the control of motor behavior by the basal ganglia.
    Annals of the New York Academy of Sciences, 1998, Nov-16, Volume: 860

    Topics: Action Potentials; Analgesics; Animals; Basal Ganglia; Benzoxazines; Bicuculline; Cannabinoids; Cyclohexanols; Dopamine; Dopamine Agonists; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Morpholines; Motor Neurons; Naphthalenes; Nerve Degeneration; Neurotransmitter Agents; Oxidopamine; Piperidines; Pyrazoles; Quinpirole; Rats; Rimonabant; Sympatholytics; Thalamic Nuclei

1998
Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo.
    Neuroscience, 1999, Volume: 89, Issue:3

    Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Nerve Degeneration; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Substantia Nigra

1999
Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-15, Volume: 19, Issue:12

    Topics: Animals; Antibodies; Anticonvulsants; Antirheumatic Agents; Bicuculline; Cell Count; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Epilepsy; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Sialoglycoproteins

1999
Free radical production correlates with cell death in an in vitro model of epilepsy.
    The European journal of neuroscience, 2000, Volume: 12, Issue:4

    Topics: Action Potentials; Aniline Compounds; Animals; Antioxidants; Bicuculline; Calcium; Cell Death; Disease Models, Animal; Epilepsy; Fluorescent Dyes; Free Radicals; GABA Antagonists; Glutathione; Hippocampus; Microscopy, Fluorescence; Nerve Degeneration; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Rhodamines; Vitamin E; Xanthenes

2000
GABA(A)-mediated toxicity of hippocampal neurons in vitro.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Animals; Anticonvulsants; Bicuculline; Cell Survival; Cells, Cultured; Epilepsy; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Vigabatrin

2000
Enhanced but fragile inhibition in the dentate gyrus in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis.
    Neuroscience, 2001, Volume: 104, Issue:2

    Topics: Animals; Bicuculline; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Agonists; GABA Antagonists; Kainic Acid; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Nerve Degeneration; Neural Inhibition; Neuronal Plasticity; Neurons; Perforant Pathway; Rats; Rats, Long-Evans; Synaptic Transmission

2001
Ketamine and MK-801 prevent degeneration of thalamic neurons induced by focal cortical seizures.
    Experimental neurology, 1989, Volume: 105, Issue:3

    Topics: Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Electroencephalography; Ketamine; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Seizures; Thalamus

1989
[Effects of systemic administration of strychnine, L-allylglycine, bicuculline and picrotoxin on the transsynaptic neural destruction in the medullary dorsal horn following transection of the rat inferior alveolar nerve].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1987, Volume: 49, Issue:10

    Topics: Allylglycine; Animals; Bicuculline; Glycine; Male; Mandibular Nerve; Medulla Oblongata; Nerve Degeneration; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine

1987
Rapid transneuronal destruction following peripheral nerve transection in the medullary dorsal horn is enhanced by strychnine, picrotoxin and bicuculline.
    Pain, 1987, Volume: 30, Issue:3

    Topics: Animals; Bicuculline; Nerve Degeneration; Neurons; Peripheral Nerve Injuries; Peripheral Nerves; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine

1987
Kainic acid seizures and neuronal cell death: insights from studies of selective lesions and drugs.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Hippocampus; Kainic Acid; Limbic System; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Phenobarbital; Rats; Seizures; Time Factors

1986
Strychnine and L-allylglycine but not bicuculline and picrotoxin induce transsynaptic degeneration following transection of the inferior alveolar nerve in adult rats.
    Brain research, 1985, Aug-26, Volume: 341, Issue:2

    Topics: Allylglycine; Animals; Bicuculline; Glycine; Mandibular Nerve; Medulla Oblongata; Nerve Degeneration; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Synapses

1985