bicuculline has been researched along with Disease Models, Animal in 244 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (4.51) | 18.7374 |
| 1990's | 21 (8.61) | 18.2507 |
| 2000's | 91 (37.30) | 29.6817 |
| 2010's | 114 (46.72) | 24.3611 |
| 2020's | 7 (2.87) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Gold, MS; Loeza-Alcocer, E | 1 |
| Ahn, Y; Cho, HJ; Jo, K; Kwak, WK; Min, B; Suh, HJ | 1 |
| Chang, J; Deng, Z; Fan, K; Lan, J; Li, D; Ma, Y; Wang, Q | 1 |
| Candiotti, KA; Gitlin, M; Rodriguez-Blanco, YF; Sevilla, A; Su, C; Weller, R; Wu, J; Yang, J; Zhang, Y; Zheng, C | 1 |
| Inoue, T; Maejima, H; Okamura, M; Takamatsu, Y | 1 |
| Goodpaster, C; Leuner, B; Maurer, S; Sabihi, S | 1 |
| Covolan, L; de Castro, AC; de Oliveira, JA; de Souza, AS; Del Bel, EA; Mograbi, KM; Sales, PJ | 1 |
| Fedinec, AL; Leffler, CW; Liu, J; Parfenova, H; Pourcyrous, M | 1 |
| Afghani, A; Ashrafpour, M; Ashrafpour, S; Dehghan, S; Ebrahim Tabar, F; Gol, M; Mousavi Majd, A; Pourabdolhossein, F | 1 |
| Li, J; Li, JX; Ling, Y; Ou, Y; Pan, F; Su, M; Wei, Q; Zhu, Q | 1 |
| Boas, DA; Devor, A; Fu, B; Gómez, CA; Sakadžić, S; Sutin, J; Uhlirova, H; Wu, W; Yaseen, MA | 1 |
| Chen, Y; Shi, Y; Wang, Y | 1 |
| Kalakh, S; Mouihate, A | 1 |
| Abrahao, KP; Alexander, NP; Ariwodola, OJ; Butler, TR; Carter, E; McCool, BA; Rau, AR; Skelly, MJ; Souza-Formigoni, ML; Weiner, JL | 1 |
| Bargas, J; Carrillo-Reid, L; Drucker-Colin, R; Fiordelisio, T; Galarraga, E; López-Huerta, VG; Tapia, D | 1 |
| Coimbra, NC; Crippa, JA; Freitas, RL; Hallak, JE; Salgado-Rohner, CJ | 1 |
| Iriki, A; Isoda, M; McCairn, KW | 1 |
| Gould, E; Hsueh, B; Pieruzzini, PR; Rada, P; Schoenfeld, TJ | 1 |
| Cheng, JK; Chiou, LC; Ho, YC | 1 |
| Bi, LL; Chen, SP; Chen, YH; Gao, TM; Geng, F; Li, SJ; Lin, S; Luo, ZY; Wang, J; Yuan, CH | 1 |
| Carriero, G; de Curtis, M; Franceschetti, S; Liautard, C; Mantegazza, M; Scalmani, P | 1 |
| Bazan, N; Lu, Y; Pei, L; Shang, Y; Tian, Q; Wang, X; Wen, R; Yang, Y; Zhao, K; Zhu, LQ | 1 |
| Deng, J; Ehrhart, J; Giunta, B; Hou, H; Obregon, D; Sawmiller, D; Tan, J; Tian, J; Zhang, SQ | 1 |
| Adamik, A; Telegdy, G | 1 |
| Bhutada, P; Deshmukh, P; Dixit, P; Kaulaskar, S; Thakur, K | 1 |
| Aguiar, JC; Guimarães, FS; Lisboa, SF; Magesto, AC; Resstel, LB | 1 |
| Akerman, S; Goadsby, PJ; Holland, PR; Lasalandra, MP | 1 |
| Almeida, A; Amorim, D; Costa, P; David-Pereira, A; Monteiro, AM; Pertovaara, A; Pinto-Ribeiro, F | 1 |
| Tanaka, M; Telegdy, G | 1 |
| Khodagholi, F; Rezayof, A; Sardari, M; Zarrindast, MR | 1 |
| Bach-Rojecky, L; Drinovac, V; Lacković, Z | 1 |
| Chan, MH; Chen, HH; Chiang, CC; Chiu, HY; Lee, MY | 1 |
| Alexander, A; Hernan, AE; Holmes, GL; Lenck-Santini, PP; Scott, RC | 1 |
| Hesami-Tackallou, S; Nasehi, M; Naseri, MH; Torabi-Nami, M; Zarrindast, MR | 1 |
| Bernardeschi, M; Busceti, CL; Cantafora, E; Fornai, F; Frenzilli, G; Giorgi, FS; Nigro, M; Scarcelli, V | 1 |
| Damasceno, RS; Moreira, TS; Takakura, AC | 1 |
| Hasanein, P; Parviz, M | 1 |
| Cha, YM; Chen, LF; Frank, CL; West, AE; Wijayatunge, R; Zannas, AS | 1 |
| Bao, W; Cui, S; Jiang, H; Liu, Q; Ma, X; Wang, X; Wang, Z; Yao, Z; Zhang, D | 1 |
| Buhler, E; Chauvin, Y; Jalabert, M; Malvache, A; Manent, JB; Peret, A; Petit, LF; Represa, A; Watrin, F | 1 |
| Liu, P; Song, W; Wang, F; Wu, C; Xiang, R; Yang, J; Yang, X; Yu, L | 1 |
| Chang, WP; Lu, HC; Shyu, BC | 1 |
| Breschi, GL; de Curtis, M; Gnatkovsky, V; Taverna, S; Uva, L | 1 |
| Asaoka, N; Kaneko, S; Nagayasu, K; Nakagawa, T; Nishitani, N; Shirakawa, H; Yamashiro, M | 1 |
| Hasegawa, M; Hongo, Y; Ikegaya, Y; Ogawa, K; Sakaguchi, G; Takasu, K | 1 |
| Chen, G; Grill, WM; Janik, JJ; Ji, RR; Peters, RV; Zhang, TC | 1 |
| Dong, X; Guan, Y; He, SQ; Raja, SN; Sdrulla, AD; Shechter, R; Shu, B; Tiwari, V; Wang, Y; Xu, Q; Yang, F; Zhang, C | 1 |
| Guan, LP; Jin, P; Li, FN; Quan, ZS; Wang, SB; Zhang, HJ | 1 |
| Hu, ZY; Li, XL; Liu, X; Ma, Q; Wang, C; Zhao, X; Zhou, DS; Zhou, WH | 1 |
| Chen, L; Dong, Z; Han, H; Tan, T; Wang, W | 1 |
| Howells, FM; Russell, VA; Sterley, TL | 2 |
| Bar-Gad, I; Israelashvili, M | 1 |
| Dudek, FE; Kadam, SD | 1 |
| Kanold, PO; Luhmann, HJ; Mordel, J; Sheikh, A; Tsohataridis, S; Zehendner, CM | 1 |
| Coimbra, NC; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Ullah, F | 1 |
| Lei, Z; Liang, Y; Xu, ZC; Zhang, H | 1 |
| Hou, Y; Li, YF; Liu, FY; Liu, J; Wan, Y; Wu, H; Yi, M; Yin, Y; Zhang, M; Zheng, L; Zhou, MM | 1 |
| Bach-Rojecky, L; Drinovac Vlah, V; Lacković, Z | 1 |
| Donahue, R; Jamal, AB; Kaushal, R; Ma, F; Taylor, BK; Westlund, KN; Zhang, L | 1 |
| Furue, H; Ishida, T; Kawamata, M; Kozuka, Y; Namiki, A; Tanaka, S; Yamakage, M | 1 |
| Chen, J; Geng, KW; Guan, SM; He, T; Li, CL; Li, Z; Lu, YF; Luo, WJ; Wang, RR; Wang, Y; Wu, FF | 1 |
| Garraway, SM; Grau, JW; Huang, YJ; Lee, KH; Murphy, L | 1 |
| Araújo, A; Brandão, LE; Cagni, FC; da Silva, RH; de Azevedo, DL; Dos Santos, WF; Miranda, A; Nôga, DA; Ribeiro, AM; Silva, D | 1 |
| Amani, M; Salari, AA | 1 |
| Aarabi, A; Mahmoudzadeh, M; Manoochehri, M; Osharina, V; Wallois, F | 1 |
| Bar-Gad, I; Israelashvili, M; Vinner, E | 1 |
| Breese, GR; Knapp, DJ; Overstreet, DH; Wills, TA | 1 |
| Auta, J; Costa, E; Guidotti, A; Impagnatiello, F; Kadriu, B | 1 |
| Gray, TS; Mickiewicz, AL; Napier, TC; Turner, MS | 1 |
| An, H; Choi, SH; Hwang, M; Kim, BH; Kim, JA; Kwon, YK; Lee, BH; Moon, JY; Shim, I; Yang, CH; Yoon, SS; Zhao, RJ | 1 |
| Li, X; Xu, MY; Xu, Y | 1 |
| Kadoyama, K; Matsumoto, A; Matsuyama, S; Taniguchi, T | 1 |
| Cranney, J; Zhang, S | 1 |
| Fischer, M; Gerich, FJ; Hägele, S; Hildebrandt, B; Katschinski, D; Müller, M; Reuter, J | 1 |
| Mabrouk, OS; Marti, M; Morari, M; Volta, M | 1 |
| Ackman, JB; Aniksztejn, L; Becq, H; Ben-Ari, Y; Cardoso, C; Crépel, V; Pellegrino, C; Represa, A | 1 |
| Dash, PK; Hoskison, MM; Hu, B; Kobori, N; Moore, AN; Orsi, S | 1 |
| Lei, Z; Li, Y; Xu, ZC | 1 |
| Luo, F; Wang, JY; Wang, N | 1 |
| Gabriel, S; Heinemann, U; Lehmann, TN; Sandow, N; Zahn, RK | 1 |
| Ferraro, G; Sardo, P | 1 |
| Fujiwara, A; Kamei, C; Takechi, K; Watanabe, Y | 1 |
| Dallel, R; Miraucourt, LS; Moisset, X; Voisin, DL | 1 |
| Agusti, A; Cauli, O; Felipo, V; Mansouri, MT | 1 |
| Bernášková, K; Mareš, P | 1 |
| Ishiwata, K; Kiyosawa, M; Mochizuki, M; Suzuki, Y | 1 |
| Baup, N; François, C; Grabli, D; Hirsch, EC; Karachi, C; Mounayar, S; Tandé, D | 1 |
| Roland, JJ; Savage, LM | 1 |
| Bar-Gad, I; Belelovsky, K; Bronfeld, M; McCairn, KW | 1 |
| Berg, S; Chambers, RA; Krishnan, GP; Morzorati, SL; O'Donnell, BF; Vohs, JL | 1 |
| O'Rourke, ST; Qian, SY; Sun, C; Yao, F; Zhang, Q | 1 |
| Matsuta, Y; Ohtake, A; Sasamata, M; Suzuki, M; Watanabe, M; Yanai-Inamura, H; Yokoyama, O | 1 |
| Baldwin, RA; Jäger, AK; Niquet, J; Pedersen, ME; Stafford, GI; van Staden, J; Wasterlain, CG | 1 |
| Khan, RS; Mathew, J; Paulose, CS; Peeyush Kumar, T | 1 |
| Awad, PN; Carmant, L; Di Cristo, G; Lema, P; Ouardouz, M | 1 |
| Basuroy, S; Leffler, CW; Parfenova, H; Tcheranova, D; Zimmermann, A | 1 |
| Bo, H; Liu, CT; Ren, XB; Zhu, J; Zhu, T | 1 |
| Mathew, J; Paulose, CS; Sadanandan, J; Soman, S | 1 |
| Bénar, CG; Bernard, C; Flynn, C; Ivanov, AI; Vanzetta, I | 1 |
| Bullis, JB; Jones, TD; Jung, S; Lau, IH; Poolos, NP; Warner, LN | 1 |
| Prado, WA; Silva, JR; Silva, ML | 1 |
| Janahmadi, M; Javan, M; Khakpay, R; Semnanian, S | 1 |
| Lee, IO; Lim, ES | 1 |
| Paz, C; Retana-Márquez, S; Rubio, C; Rubio-Osornio, M; Verónica Custodio, ML | 1 |
| Brandão, ML; Cabral, A; Nobre, MJ | 1 |
| An, YY; Cao, FL; Chen, J; Gao, CY; Gong, KR; He, Y; Li, H; Lin, Q; Wang, DD; Zhang, FK | 1 |
| Avoli, M; Dzakpasu, R; Gonzalez-Sulser, A; Motamedi, GK; Vicini, S; Wang, J | 1 |
| Alania, M; Doreulee, N; Kapanadze, Ts; Skhirtladze, E; Vashalomidze, G | 1 |
| Bai, Y; Chen, L; Chi, X; Li, L; Sokabe, M; Yang, R; Zhou, R; Zhu, Y | 1 |
| Beleboni, RO; Cunha, AO; dos Santos, WF; Fachim, HA; Faggion, SA; Gavin, AS; Pereira, AM | 1 |
| Ali, U; Feng, JJ; Gui, ZH; Hui, YP; Li, LB; Liu, J; Niu, XL; Wu, ZH; Zhang, QJ | 1 |
| Chung, JM; Chung, K; Kim, HK; Kim, HY; Lee, KY; Wang, J; Yowtak, J | 1 |
| Herman, JP; Jones, KR; Myers, B | 1 |
| Aziz, TZ; Green, AL; Jenkinson, N; Nandi, D; Pereira, EA; Stein, JF | 1 |
| Maione, S; Neugebauer, V; Palazzo, E; Ren, W | 1 |
| Abercrombie, ED; Callahan, JW; Farrar, AM | 1 |
| Ji, G; Neugebauer, V | 1 |
| Betancourt, L; Catlow, B; Chiurillo, M; Hernández, L; López, W; Loureiro, N; Mosquera, E; Rada, P; Skirzewski, M | 1 |
| Ikeda, T; Kasahara, Y; Ohshima, M; Taguchi, A; Tsuji, M | 1 |
| Carlisle, HJ; Gunapala, KM; Indersmitten, T; Kennedy, MB; Khorosheva, E; Luong, TN; Medina-Marino, A; O'Dell, TJ; Patterson, PH; Schenker, L; Steele, AD | 1 |
| Chen, Q; Su, SF; Wang, HH; Wang, NB; Yang, AM; Yang, SB | 1 |
| Chang, WP; Lee, CM; Shyu, BC; Vogt, BA; Wu, JS | 1 |
| Micov, AM; Paranos, SLj; Stepanović-Petrović, RM; Tomić, MA | 1 |
| Li, X; Liu, W; Wei, J; Yan, Z; Yuen, EY; Zhong, P | 1 |
| Bernášková, K; Kubová, H; Mareš, P | 1 |
| Barchini, J; Jabbur, SJ; Linderoth, B; Meyerson, BA; Saadé, NE; Shamaa, F; Song, Z; Tchachaghian, S | 1 |
| Schally, AV; Telegdy, G | 1 |
| de Araújo, DB; Fernandes, A; Foresti, ML; Garcia-Cairasco, N; Marroni, SS; Rodrigues, MC; Romcy-Pereira, RN; Rossetti, F | 1 |
| Malmierca, E; Martin, YB; Nuñez, A | 1 |
| Boccella, S; De Chiaro, M; de Novellis, V; Gatta, L; Giordano, C; Guida, F; Luongo, L; Maione, S; Marabese, I; Palazzo, E; Rossi, F; Siniscalco, D; Vita, D | 1 |
| Dehpour, AR; Fakhraei, N; Gharedaghi, MH; Javadi-Paydar, M; Javadian, P; Salehi-Sadaghiani, M; Tavangar, SM; Yousefzadeh-Fard, Y | 1 |
| Hirooka, Y; Kishi, T; Shinohara, K; Sunagawa, K | 1 |
| Decker, AL; DesJardin, JT; Forcelli, PA; Gale, K; Holmes, AL; Malkova, L; Teferra, M; West, EA | 1 |
| Amestoy, V; Aouizerate, B; Bioulac, B; Burbaud, P; Cardoit, L; Dovero, S; Guehl, D; Lambrecq, V; Langbour, N; Nguyen, TH; Rotge, JY; Tignol, J | 1 |
| Allingham, RR; Hammes, NM; Johnson, PL; McKinnon, SJ; Samuels, BC; Shekhar, A | 1 |
| Chaigneau, M; Epinat, J; Féger, J; François, C; Sgambato-Faure, V; Tandé, D; Tremblay, L; Worbe, Y | 1 |
| Aoyama, K; Kikuchi-Utsumi, K; Matsumura, N; Nakaki, T; Sakamaki, K; Watabe, M | 1 |
| Eisenach, JC; Hayashida, K; Kimura, M; Obata, H; Saito, S | 1 |
| Bird, A; Cobb, SR; Ganley, R; McLeod, F; Selfridge, J; Williams, L | 1 |
| Abdulla, MH; Hassan, Z; Johns, EJ; Sattar, MZ; Suhaimi, FW; Yusof, AP; Yusoff, NH | 1 |
| Fukuda, A; Iwata, S; Kaneko, T; Kumada, T; Morishima, T; Wang, T; Yanagawa, Y; Yoshida, S | 1 |
| Babri, S; Doosti, MH; Fatehi-Gharehlar, L; Kosari-Nasab, M; Pakzad, S | 1 |
| Baumann, D; Mueggler, T; Rausch, M; Rudin, M; Staufenbiel, M; Sturchler-Pierrat, C | 1 |
| Benardete, EA; Kriegstein, AR | 1 |
| Bough, KJ; Eagles, DA; Gudi, K; Han, FT; Rathod, AH | 1 |
| Beachy, PA; Berman, DM; Chen, JK; Cooper, MK; Eberhart, CG; Hallahan, AR; Karhadkar, SS; Olson, JM; Pritchard, JI; Taipale, J; Watkins, DN | 1 |
| Matsumura, M | 1 |
| Misgeld, U; Yanovsky, Y | 1 |
| Leung, LS; Wu, K | 2 |
| Browning, RA; Clough, RW; Jobe, PC; Merrill, MA | 1 |
| Clement, AB; Cravatt, BF; Hawkins, EG; Lichtman, AH | 1 |
| Habaguchi, T; Ohtinata-Sugimoto, J; Saitoh, K; Sakamoto, T; Takakusaki, K | 1 |
| Perez Velazquez, JL | 1 |
| Anschel, DJ; Fisher, RS; Ortega, E | 1 |
| Salam, A; Shabanzadeh, AP; Shuaib, A; Wang, CX; Yang, T | 1 |
| Hamann, M; Richter, A | 1 |
| Drew, GM; Duggan, AW; Siddall, PJ | 1 |
| Bae, YC; Cho, JH; Choi, BJ; Choi, IS; Jung, SC; Kim, JH; Lee, MG | 1 |
| Blumenfeld, H; Erdogan, E; Herman, P; Hyder, F; Nersesyan, H | 1 |
| Collins, JG; Kawamata, M; Koshizaki, M; Kozuka, Y; Namiki, A; Narimatsu, E; Shimada, SG; Takahashi, T | 1 |
| Busceti, CL; Fornai, F; Gale, K; Kondratyev, A | 1 |
| Behr, J; Heinemann, U; Kivi, A; Knopp, A; Wozny, C | 1 |
| Frye, CA; Rhodes, ME | 1 |
| Arisi, GM; Bertti, P; Dal-Cól, ML; Del Vecchio, F; Fernandes, A; Foresti, ML; Furtado, MA; Garcia-Cairasco, N; Rodrigues, MC; Rossetti, F; Santos, FL | 1 |
| Campbell, S; Hablitz, JJ | 1 |
| Naylor, DE; Wasterlain, CG | 1 |
| Holmes, GL; Isaev, D; Isaeva, E; Khazipov, R | 1 |
| Asimiadou, S; Bittigau, P; Dzietko, M; Felderhoff-Mueser, U; Ikonomidou, C; Kaindl, AM; Manthey, D; Mozrzymas, JW; Pesditschek, S; Pytel, M; Sifringer, M; Studniarczyk, D | 1 |
| Covey, DF; Jevtovic-Todorovic, V; Pathirathna, S; Todorovic, SM | 1 |
| Budzińska, K | 1 |
| de Curtis, M; Librizzi, L; Uva, L; Wendling, F | 1 |
| Beck, H; Kirschstein, T; von der Brelie, C; Waltereit, R; Zhang, L | 1 |
| Nadler, JV; Timofeeva, O | 1 |
| Debanne, D; Gähwiler, BH; Thompson, SM | 1 |
| Browning, RA; Cranick, S; Patrylo, PR | 1 |
| Borbély, S; Détári, L; Halasy, K; Somogyvári, Z; Világi, I | 1 |
| Dhir, A; Kulkarni, SK; Naidu, PS | 1 |
| Amabeoku, GJ; Ojewole, JA | 1 |
| Lesser, RP; Motamedi, GK; Ortinski, PI; Rogawski, MA; Salazar, P; Smith, EL; Vicini, S; Webber, WR | 1 |
| Aker, RG; Cakmak, YO; Cavdar, S; Onat, FY; Ozkaynakçi, AE; Ozyurt, HB; Saka, E; Sehirli, U; Yananli, HR | 1 |
| Beleboni, Rde O; Coutinho-Netto, J; Cunha, AO; dos Santos, WF; Gelfuso, EA; Liberato, JL; Mortari, MR | 1 |
| Chen, SR; Pan, HL; Wang, XL; Zhang, HM | 1 |
| Blandini, F; Fornai, F; Giorgi, FS; Mauceli, G; Murri, L; Paparelli, A; Ruggieri, S | 1 |
| Kubová, H; Mares, P; Tchekalarova, J | 1 |
| Fedinec, AL; Leffler, CW; Parfenova, H; Tcheranova, D; Zimmermann, A | 1 |
| Abu-Shaweesh, JM | 1 |
| Bertram, EH; Kapur, J; Rajasekaran, K | 1 |
| Chopde, CT; Hirani, K; Kokare, DM; Sharma, AN; Subhedar, NK; Ugale, RR | 1 |
| Ojewole, JA | 1 |
| Chancellor, MB; de Groat, WC; Hiragata, S; Miyazato, M; Sasatomi, K; Sugaya, K; Yoshimura, N | 1 |
| Aker, RG; Aypak, C; Goren, MZ; Onat, FY; Terzioğlu, B; Yananli, HR | 1 |
| Carney, PR; Chen, H; Jiang, H; Liu, Z; Roper, SN; Yuan, Z; Zhang, Q | 1 |
| Bosković, B; Kocev, N; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM | 1 |
| Baraldi, M; Zeneroli, ZL | 1 |
| DiMicco, JA; Gillis, RA; Hamosh, P; Norman, WP; Segal, SA; Williford, DJ; Yamada, KA | 1 |
| Crossman, AR; Jackson, A | 1 |
| Haglund, MM; Schwartzkroin, PA | 1 |
| de Feo, MR; Mecarelli, O; Ricci, GF | 1 |
| Rees, H; Sluka, KA; Westlund, KN; Willis, WD | 1 |
| Ahmad, I; Pleuvry, BJ | 1 |
| Shekhar, A | 1 |
| Ahmad, I; Lauretti, GR; Pleuvry, BJ | 1 |
| Dubur, GIa; Germane, OK; Karpova, MN; Klusha, VE; Pankov, OIu | 1 |
| Müller, M | 1 |
| Czuczwar, SJ; Dzieciuch, J; Kleinrok, Z; Klonowski, P; Tutka, P | 1 |
| Jefferys, JG; Whittington, MA | 1 |
| Biella, G; de Curtis, M; Forti, M | 1 |
| Eder, HG; Fisher, RS; Jones, DB | 1 |
| Costa da Costa, J; Russo, RE; Velluti, JC | 1 |
| Akimitsu, T; Amano, T; Arita, K; Hanaya, R; Iida, K; Ishihara, K; Kurisu, K; Sasa, M; Serikawa, T | 1 |
| Niemi-Junkola, U; Redgrave, P; Shehab, S | 1 |
| Köhling, R; Lücke, A; Mayer, T; Musshoff, U; Osterfeld, M; Schütte, W; Speckmann, EJ; Wolf, P | 1 |
| de Curtis, M; Forti, M; Radici, C | 1 |
| Born, DE; Dubach, M; Gunderson, VM; Maravilla, KR; Robbins, CA; Schwartzkroin, PA; Szot, P; Wenzel, HJ; Zierath, DK | 1 |
| Alkadhi, KA; Otoom, SA | 1 |
| Baumann, D; Bjelke, B; Bochelen, D; Porszasz, R; Reese, T; Rudin, M; Sauter, A | 1 |
| Carlen, PL; Frantseva, MV; Hwang, PA; Velazquez, JL | 1 |
| Gause, L; Kampov-Polevoy, AB; Matthews, DB; Morrow, AL; Overstreet, DH | 1 |
| Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT | 1 |
| Chapman, DF; Lapchak, PA; Nunez, SY; Zivin, JA | 1 |
| Born, DE; Dubach, MF; Gunderson, VM; Jürgen Wenzel, H; Maravilla, KR; Robbins, CA; Schwartzkroin, PA; Szot, P; Zierath, D | 1 |
| Pralong, E; Stoop, R | 1 |
| Kaur, G; Kulkarni, SK; Raghavendra, V | 1 |
| Pape, HC; Staak, R | 1 |
| Dudek, FE; Wuarin, JP | 1 |
| Biella, G; de Curtis, M; Librizzi, L | 1 |
| Jeng, J; Ratzliff, AD; Santhakumar, V; Soltesz, I; Toth, Z | 1 |
| Gustaw, K; Rubaj, A; Sieklucka-Dziuba, M; Zgodzinski, W | 1 |
| Ito, M; Katoh, M; Kishikawa, M; Kitajima, S; Seto-Ohshima, A | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Hamani, C; Mello, LE; Sakabe, S | 1 |
| Bioulac, B; Burbaud, P; Escola, L; Guehl, D; Macia, F; Michelet, T | 1 |
| Livermore, A; Stevens, JR | 1 |
| Brierley, JB; Meldrum, BS; Papy, JJ; Toure, MF | 1 |
| Dasheiff, RM; Sacks, DS | 1 |
| Gale, K; Pazos, A; Peterson, CJ; Vinayak, S | 1 |
| Burnham, WM; Mingo, NS | 1 |
| Egbe, P; Engel, JA; Liljequist, S; Söderpalm, B | 1 |
| Lee, RJ; Lomax, P; McCabe, RT; Olsen, RW; Wamsley, JK | 1 |
| Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B | 1 |
| Biziere, K; Brochard, J; Brodin, R; Chambon, JP; Hallot, A; Merlier, J | 1 |
| Mori, K; Oshima, E; Shingu, K; Urabe, N | 1 |
3 review(s) available for bicuculline and Disease Models, Animal
| Article | Year |
|---|---|
In vivo experimental models of epilepsy.
Topics: Aluminum Hydroxide; Animals; Bicuculline; Cobalt; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; Epilepsy, Reflex; Flurothyl; gamma-Aminobutyric Acid; Humans; Kainic Acid; Kindling, Neurologic; Muscarinic Agonists; Papio; Penicillins; Pentylenetetrazole; Pilocarpine; Tetanus Toxin; Zinc Compounds | 2010 |
Pedunculopontine stimulation from primate to patient.
Topics: Animals; Bicuculline; Biophysics; Convulsants; Deep Brain Stimulation; Disease Models, Animal; GABA-A Receptor Agonists; History, 20th Century; Humans; Macaca; Male; Muscimol; Parkinson Disease; Pedunculopontine Tegmental Nucleus | 2011 |
Experimental parkinsonism in primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Apomorphine; Basal Ganglia; Bicuculline; Cerebral Cortex; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrocoagulation; GABA Antagonists; Globus Pallidus; Humans; Models, Neurological; MPTP Poisoning; Muscle Rigidity; Neurotoxins; Parkinsonian Disorders; Primates; Substance-Related Disorders; Substantia Nigra; Tegmentum Mesencephali; Thalamus | 2001 |
241 other study(ies) available for bicuculline and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Peripheral GABAA receptor signaling contributes to visceral hypersensitivity in a mouse model of colitis.
Topics: Animals; Bicuculline; Colitis; Colon; Dextran Sulfate; Diazepam; Disease Models, Animal; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Muscimol; Pain; Receptors, GABA-A | 2022 |
GABA
Topics: Acids; Animals; Bicuculline; Caffeine; Cyclohexenes; Disease Models, Animal; Electroencephalography; Flavonoids; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Humulus; Hypnotics and Sedatives; Mice; Picrotoxin; Propiophenones; Receptors, GABA-A; Sleep; Sleep Initiation and Maintenance Disorders; Terpenes | 2021 |
Inhibition of GABA
Topics: Animals; beta Catenin; Bicuculline; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; gamma-Aminobutyric Acid; Lacticaseibacillus casei; Mice; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen; RNA | 2022 |
The mechanism of chronic nicotine exposure and nicotine withdrawal on pain perception in an animal model.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Down-Regulation; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Naloxone; Nicotine; Pain Perception; Pain Threshold; Rats; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Time Factors; Up-Regulation | 2020 |
Low-Level Inhibition of GABAergic Synapses Enhances Gene Expressions Crucial for Neuronal Plasticity in the Hippocampus After Ischemic Stroke.
Topics: Animals; Bicuculline; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Disks Large Homolog 4 Protein; GABA-A Receptor Antagonists; GABAergic Neurons; Gene Expression Regulation; Hippocampus; Infarction, Middle Cerebral Artery; Male; Nerve Tissue Proteins; Neural Inhibition; Neuronal Plasticity; Rats, Sprague-Dawley; Receptor, trkB; Receptors, Growth Factor; Synaptic Transmission; Synaptophysin | 2020 |
GABA in the medial prefrontal cortex regulates anxiety-like behavior during the postpartum period.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Male; Maternal Deprivation; Muscimol; Prefrontal Cortex; Puerperal Disorders; Rats, Sprague-Dawley | 2021 |
Effects of GABAa receptor antagonists on motor behavior in pharmacological Parkinson's disease model in mice.
Topics: Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; Flumazenil; GABA-A Receptor Antagonists; Gait; Mice; Motor Activity; Parkinsonian Disorders | 2017 |
Preventing harmful effects of epileptic seizures on cerebrovascular functions in newborn pigs: does sex matter?
Topics: Animals; Animals, Newborn; Antioxidants; Astrocytes; Bicuculline; Boranes; Carbonates; Cerebral Arteries; Cerebrovascular Disorders; Disease Models, Animal; Endothelial Cells; Female; Humans; Male; Pia Mater; Seizures; Sex Factors; Sus scrofa; Time Factors; Vasodilation; Vasodilator Agents | 2017 |
Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus.
Topics: Animals; Avoidance Learning; Bicuculline; Demyelinating Diseases; Disease Models, Animal; GABA-A Receptor Antagonists; Hippocampus; Learning; Male; Maze Learning; Memory; Memory Disorders; Multiple Sclerosis; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Spatial Memory | 2018 |
Anti-allodynic effects of N-demethylsinomenine, an active metabolite of sinomenine, in a mouse model of postoperative pain.
Topics: Analgesics; Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Morphinans; Pain, Postoperative; Receptors, GABA-A | 2018 |
Phasor analysis of NADH FLIM identifies pharmacological disruptions to mitochondrial metabolic processes in the rodent cerebral cortex.
Topics: Animals; Bicuculline; Biomarkers; Cerebral Cortex; Disease Models, Animal; Humans; Intravital Microscopy; Microscopy, Fluorescence, Multiphoton; Mitochondria; Models, Biological; NAD; Nonlinear Dynamics; Rats, Sprague-Dawley; Rodentia; Seizures | 2018 |
Kir2.1 Channel Regulation of Glycinergic Transmission Selectively Contributes to Dynamic Mechanical Allodynia in a Mouse Model of Spared Nerve Injury.
Topics: Animals; Bicuculline; Disease Models, Animal; Glycine; Hyperalgesia; Imidazoles; Inhibitory Postsynaptic Potentials; Male; Mice, Inbred C57BL; Neurons; Neurotransmitter Agents; Peripheral Nerve Injuries; Phenanthrolines; Potassium Channels, Inwardly Rectifying; Receptors, GABA-A; Receptors, Glycine; Strychnine; Synaptic Transmission; Tissue Culture Techniques; Touch | 2019 |
Enhanced remyelination during late pregnancy: involvement of the GABAergic system.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Bicuculline; Corpus Callosum; Demyelinating Diseases; Disease Models, Animal; Female; Finasteride; GABA Antagonists; Lysophosphatidylcholines; Male; Microglia; Multiple Sclerosis; Myelin Proteins; Myelin Sheath; Nerve Tissue Proteins; Oligodendrocyte Precursor Cells; Oligodendroglia; Pregnancy; Pregnancy Complications; Pregnanolone; Puerperal Disorders; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Remyelination | 2019 |
Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration.
Topics: Alcoholic Intoxication; Analysis of Variance; Animals; Bicuculline; Biophysics; Central Nervous System Depressants; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Ethanol; GABA-A Receptor Antagonists; Gene Expression Regulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Locomotion; Male; Mice; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Self Administration; Synaptic Transmission | 2013 |
The balance of striatal feedback transmission is disrupted in a model of parkinsonism.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Lidocaine; Lysine; Male; Mice; Mice, Transgenic; Monte Carlo Method; Neostriatum; Neural Inhibition; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission; Time Factors; Valine | 2013 |
Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid
Topics: Analysis of Variance; Animals; Bicuculline; Defense Mechanisms; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; Hyperalgesia; Hypothalamus; Instinct; Male; Microinjections; Pain Measurement; Pain Threshold; Panic; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-A | 2013 |
Deep brain stimulation reduces Tic-related neural activity via temporal locking with stimulus pulses.
Topics: Action Potentials; Animals; Bicuculline; Corpus Striatum; Deep Brain Stimulation; Disease Models, Animal; Electromyography; GABA Antagonists; Globus Pallidus; Macaca; Male; Microinjections; Neural Inhibition; Neurons; Tic Disorders; Time Factors | 2013 |
Physical exercise prevents stress-induced activation of granule neurons and enhances local inhibitory mechanisms in the dentate gyrus.
Topics: Analysis of Variance; Animals; Bicuculline; Bromodeoxyuridine; Dentate Gyrus; Disease Models, Animal; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Genes, Immediate-Early; Interneurons; Male; Mice; Mice, Inbred C57BL; Microdialysis; Nerve Tissue Proteins; Neural Inhibition; Physical Conditioning, Animal; Stress, Psychological; Swimming | 2013 |
Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic pain.
Topics: Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Neuralgia; Neurons; Pain Measurement; Patch-Clamp Techniques; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Spinal Nerves; Synaptic Transmission; Tetrodotoxin | 2013 |
Enhanced excitability in the infralimbic cortex produces anxiety-like behaviors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Anxiety; Bicuculline; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Prefrontal Cortex | 2013 |
Hippocampal hyperexcitability and specific epileptiform activity in a mouse model of Dravet syndrome.
Topics: 4-Aminopyridine; Age Factors; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsies, Myoclonic; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Hippocampus; Hyperthermia, Induced; In Vitro Techniques; Kynurenic Acid; Mice; Mice, Knockout; NAV1.1 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Pyramidal Cells | 2013 |
EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability.
Topics: Animals; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; Guanine Nucleotide Exchange Factors; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Kainic Acid; KATP Channels; Male; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Probability; Protein Binding; Quinoxalines; Synaptosomes; Transduction, Genetic | 2013 |
Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Bicuculline; CHO Cells; Cricetulus; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flavanones; GABA-A Receptor Antagonists; Gene Expression Regulation; Humans; Maze Learning; Mice; Mice, Transgenic; Mutation; Transfection | 2013 |
Involvement of transmitters in the anxiolytic action of urocortin 3 in mice.
Topics: Analysis of Variance; Animals; Anxiety; Atropine; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Maze Learning; Methysergide; Mice; Naloxone; Neurotransmitter Agents; Propranolol; Time Factors; Urocortins | 2013 |
Effects of agomelatine in a murine model of obsessive-compulsive disorder: interaction with meta-chlorophenylpiperazine, bicuculline, and diazepam.
Topics: Acetamides; Animals; Antidepressive Agents; Behavior, Animal; Bicuculline; Diazepam; Disease Models, Animal; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred C57BL; Motor Activity; Obsessive-Compulsive Disorder; Piperazines; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2013 |
Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats.
Topics: Animals; Anxiety; Apomorphine; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA-A Receptor Antagonists; Male; Maze Learning; Nitric Oxide Synthase; Oxadiazoles; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2013 |
Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and "triptan" receptors: implications in migraine.
Topics: Animals; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Endocannabinoids; GABA-A Receptor Antagonists; Male; Microinjections; Nerve Fibers, Myelinated; Pain; Periaqueductal Gray; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Skin; Trigeminal Nuclei | 2013 |
Pronociception from the dorsomedial nucleus of the hypothalamus is mediated by the rostral ventromedial medulla in healthy controls but is absent in arthritic animals.
Topics: Animals; Arthritis; Bicuculline; Carrageenan; Disease Models, Animal; Dorsomedial Hypothalamic Nucleus; Drug Interactions; GABA-A Receptor Antagonists; Hyperalgesia; Male; Medulla Oblongata; Neural Pathways; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Reaction Time | 2013 |
Neurotransmissions of antidepressant-like effects of neuromedin U-23 in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Atropine; Bicuculline; Depression; Disease Models, Animal; Freezing Reaction, Cataleptic; GABA-A Receptor Antagonists; Male; Methysergide; Mice; Muscarinic Antagonists; Neuropeptides; Serotonin Antagonists; Swimming; Synaptic Transmission | 2014 |
Basolateral amygdala GABA-A receptors mediate stress-induced memory retrieval impairment in rats.
Topics: Amygdala; Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Memory Disorders; Mental Recall; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Stress, Psychological | 2014 |
Association of antinociceptive action of botulinum toxin type A with GABA-A receptor.
Topics: Animals; Bicuculline; Botulinum Toxins, Type A; Disease Models, Animal; Drug Administration Routes; Formaldehyde; Hyperalgesia; Neurotoxins; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-A; Sciatica | 2014 |
N-acetylcysteine modulates hallucinogenic 5-HT(2A) receptor agonist-mediated responses: behavioral, molecular, and electrophysiological studies.
Topics: Acetylcysteine; Action Potentials; Amino Acids; Amphetamines; Animals; Benzoates; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Early Growth Response Protein 2; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA-A Receptor Antagonists; Glycine; Hallucinations; Hallucinogens; Male; Mice; Proto-Oncogene Proteins c-fos; Receptors, Metabotropic Glutamate; Xanthenes | 2014 |
Attention deficit associated with early life interictal spikes in a rat model is improved with ACTH.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Bicuculline; Disease Models, Animal; Epilepsies, Partial; GABA-A Receptor Antagonists; Injections, Subcutaneous; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2014 |
Involvement of the CA1 GABAA receptors in MK-801-induced anxiolytic-like effects: an isobologram analysis.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; CA1 Region, Hippocampal; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; GABA Agents; Male; Maze Learning; Microinjections; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A | 2014 |
Region-specific DNA alterations in focally induced seizures.
Topics: Animals; Bicuculline; Brain; Comet Assay; Convulsants; Disease Models, Animal; DNA Damage; Electroencephalography; Male; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Seizures | 2014 |
Regulation of the chemosensory control of breathing by Kölliker-Fuse neurons.
Topics: Animals; Bicuculline; Blood Pressure; Chemoreceptor Cells; Disease Models, Animal; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Heart Rate; Hypercapnia; Hypoxia; Male; Muscimol; Pons; Rats; Rats, Wistar; Receptors, GABA; Reflex; Respiration; Signal Transduction; Time Factors | 2014 |
Role of GABAA receptor in modulation of acute thermal pain using a rat model of cholestasis.
Topics: Acute Pain; Animals; Bicuculline; Cholestasis; Disease Models, Animal; Muscimol; Naloxone; Rats; Receptors, GABA-A; Rotarod Performance Test | 2014 |
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival.
Topics: 4-Aminopyridine; Animals; Astrocytes; Bicuculline; Cell Survival; Cells, Cultured; Disease Models, Animal; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Jumonji Domain-Containing Histone Demethylases; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Neurons; Pilocarpine; Potassium Channel Blockers; RNA Interference; Seizures | 2014 |
Role of spinal GABAA receptor reduction induced by stress in rat thermal hyperalgesia.
Topics: Analysis of Variance; Animals; Bicuculline; Disease Models, Animal; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Hyperalgesia; Male; Muscimol; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Spinal Cord; Stress, Psychological; Time Factors | 2014 |
Normotopic cortex is the major contributor to epilepsy in experimental double cortex.
Topics: Animals; Bicuculline; Cerebral Cortex; Classical Lissencephalies and Subcortical Band Heterotopias; Convulsants; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroencephalography; Electrophysiological Phenomena; Epilepsy; Gene Knockdown Techniques; Microtubule-Associated Proteins; Neocortex; Nerve Net; Neuropeptides; Pentylenetetrazole; Rats; Rats, Transgenic; Seizures; Somatosensory Cortex | 2014 |
Uridine decreases morphine-induced behavioral sensitization by decreasing dorsal striatal dopamine release possibly via agonistic effects at GABAA receptors.
Topics: Analgesics, Opioid; Animals; Animals, Inbred Strains; beta-Alanine; Bicuculline; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Morphine; Motor Activity; Receptors, GABA-A; Time Factors; Uracil; Uridine | 2014 |
Treatment with direct-current stimulation against cingulate seizure-like activity induced by 4-aminopyridine and bicuculline in an in vitro mouse model.
Topics: 4-Aminopyridine; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Gyrus Cinguli; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Seizures; Treatment Outcome | 2015 |
Synchronous inhibitory potentials precede seizure-like events in acute models of focal limbic seizures.
Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Computer Simulation; Convulsants; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Guinea Pigs; In Vitro Techniques; Models, Biological; Neural Inhibition; Potassium Channel Blockers; Quinoxalines; Seizures | 2015 |
Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus.
Topics: Animals; Antidepressive Agents; Benzodiazepines; Bicuculline; Citalopram; Depressive Disorder; Disease Models, Animal; Dorsal Raphe Nucleus; Female; Fluoxetine; GABA-A Receptor Antagonists; GABAergic Neurons; Male; Mice, Inbred C57BL; Neural Inhibition; Olanzapine; Piperazines; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonergic Neurons; Serotonin Antagonists; Sulfonamides; Tissue Culture Techniques | 2015 |
Heterogeneous effects of antiepileptic drugs in an in vitro epilepsy model--a functional multineuron calcium imaging study.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Calcium; Convulsants; Disease Models, Animal; Epilepsy; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Statistics, Nonparametric | 2015 |
Spinal sensory projection neuron responses to spinal cord stimulation are mediated by circuits beyond gate control.
Topics: Action Potentials; Animals; Bicuculline; Computer Simulation; Disease Models, Animal; GABA-A Receptor Antagonists; Lumbar Vertebrae; Male; Microelectrodes; Models, Neurological; Neural Inhibition; Neuralgia; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatic Nerve; Sensory Receptor Cells; Spinal Cord; Spinal Cord Stimulation | 2015 |
Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agents; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Green Fluorescent Proteins; Long-Term Synaptic Depression; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Fibers; Neuralgia; Posterior Horn Cells; Red Fluorescent Protein; Sensory Thresholds; Spinal Cord; Spinal Nerves; Vesicular Glutamate Transport Protein 2 | 2015 |
Synthesis and Anticonvulsant Activity Evaluation of 4-Phenyl-[1,2,4]triazolo[4,3-a]quinazolin-5(4H)-one and Its Derivatives.
Topics: Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Brain; Disease Models, Animal; Drug Design; Electroshock; Mice; Molecular Structure; Motor Activity; Pentylenetetrazole; Quinazolinones; Rotarod Performance Test; Seizures; Structure-Activity Relationship; Time Factors; Triazoles | 2015 |
Antinociceptive effects of fisetin against diabetic neuropathic pain in mice: Engagement of antioxidant mechanisms and spinal GABAA receptors.
Topics: Analgesics; Animals; Antioxidants; Bicuculline; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Flavonoids; Flavonols; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Oxidative Stress; Reactive Oxygen Species; Receptors, GABA-A; Spinal Cord; Streptozocin | 2015 |
GABA(A) Receptors in the Central Nucleus of the Amygdala Are Involved in Pain- and Itch-Related Responses.
Topics: Animals; Behavior, Animal; Bicuculline; Central Amygdaloid Nucleus; Disease Models, Animal; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Muscimol; Pain; Pruritus; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2016 |
Genetically determined differences in noradrenergic function: The spontaneously hypertensive rat model.
Topics: Animals; Bicuculline; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Genetic Predisposition to Disease; Glutamic Acid; Hippocampus; Male; Maternal Deprivation; Norepinephrine; Potassium; Random Allocation; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Species Specificity; Stress, Psychological | 2016 |
Corticostriatal Divergent Function in Determining the Temporal and Spatial Properties of Motor Tics.
Topics: Algorithms; Animals; Bicuculline; Cerebral Cortex; Computer Simulation; Corpus Striatum; Disease Models, Animal; Electric Stimulation; Female; GABA Antagonists; Male; Nerve Net; Rats; Rats, Long-Evans; Refractory Period, Electrophysiological; Stereotyped Behavior; Tics; Tourette Syndrome | 2015 |
Temporal progression of evoked field potentials in neocortical slices after unilateral hypoxia-ischemia in perinatal rats: Correlation with cortical epileptogenesis.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy; Evoked Potentials; Functional Laterality; GABA Antagonists; Hypoxia-Ischemia, Brain; In Vitro Techniques; Neocortex; Rats; Rats, Sprague-Dawley | 2016 |
Mild systemic inflammation and moderate hypoxia transiently alter neuronal excitability in mouse somatosensory cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Bicuculline; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; GABA-A Receptor Antagonists; Gene Expression Regulation; Hypoxia; In Vitro Techniques; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons; Potassium Chloride; Somatosensory Cortex | 2016 |
CB
Topics: Animals; Arachidonic Acids; Bicuculline; Disease Models, Animal; Endocannabinoids; Escape Reaction; GABA-A Receptor Antagonists; Male; Panic Disorder; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-A; TRPV Cation Channels; Ventromedial Hypothalamic Nucleus | 2017 |
Reduced expression of IA channels is associated with post-ischemic seizures.
Topics: Animals; Bicuculline; Blotting, Western; Brain; Brain Ischemia; Cell Death; Disease Models, Animal; Disease Susceptibility; Gene Expression; Immunohistochemistry; Kv Channel-Interacting Proteins; Male; Neurons; Rats, Wistar; Seizures; Severity of Illness Index; Shal Potassium Channels | 2016 |
Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury.
Topics: Animals; Antineoplastic Agents; Bicuculline; Calcium-Binding Proteins; Carrier Proteins; Disease Models, Animal; GABA Antagonists; Glial Fibrillary Acidic Protein; Hyperalgesia; Isoquinolines; Mice; Microfilament Proteins; Neurotransmitter Agents; Pain Measurement; Phosphopyruvate Hydratase; Purines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatica; Thalamus; Up-Regulation | 2016 |
Antinociceptive action of botulinum toxin type A in carrageenan-induced mirror pain.
Topics: Analgesics; Animals; Bicuculline; Botulinum Toxins, Type A; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Functional Laterality; Hyperalgesia; Male; Naloxone; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Cord; Synaptosomal-Associated Protein 25 | 2016 |
GABA-A receptor activity in the noradrenergic locus coeruleus drives trigeminal neuropathic pain in the rat; contribution of NAα1 receptors in the medial prefrontal cortex.
Topics: Activating Transcription Factor 3; Adrenergic alpha-Antagonists; Adrenergic Neurons; Animals; Bicuculline; Chronic Pain; Disease Models, Animal; Facial Pain; GABA-A Receptor Antagonists; Hyperalgesia; Idazoxan; Locus Coeruleus; Male; Neuralgia; Oxathiins; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Trigeminal Nerve Injuries | 2016 |
Changes in synaptic transmission of substantia gelatinosa neurons after spinal cord hemisection revealed by analysis using in vivo patch-clamp recording.
Topics: Anesthetics, Intravenous; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Functional Laterality; Hyperalgesia; Male; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Strychnine; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin; Urethane | 2016 |
Ethanol Increases Mechanical Pain Sensitivity in Rats via Activation of GABAA Receptors in Medial Prefrontal Cortex.
Topics: Animals; Bicuculline; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Depressants; Disease Models, Animal; Ethanol; GABA Antagonists; GABA-A Receptor Agonists; Hyperalgesia; Male; Microinjections; Muscimol; Pain Measurement; Pain Threshold; Phosphopyruvate Hydratase; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA; Statistics, Nonparametric | 2016 |
Acute spinal cord injury (SCI) transforms how GABA affects nociceptive sensitization.
Topics: Acetates; Analysis of Variance; Animals; Bicuculline; Bumetanide; Capsaicin; Disease Models, Animal; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Hyperalgesia; Indenes; K Cl- Cotransporters; Lipopolysaccharides; Male; MAP Kinase Signaling System; Muscimol; Nociception; Pain Measurement; Physical Stimulation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Potassium Chloride Symporter Inhibitors; Spinal Cord Injuries; Symporters; Time Factors | 2016 |
Anticonvulsant Effects of Fractions Isolated from Dinoponera quadriceps (Kempt) Ant Venom (Formicidae: Ponerinae).
Topics: Animals; Ant Venoms; Anticonvulsants; Ants; Bicuculline; Disease Models, Animal; Male; Mice; Seizures | 2016 |
Neonatal blockade of GABA-A receptors alters behavioral and physiological phenotypes in adult mice.
Topics: Adaptation, Ocular; Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Bicuculline; Body Weight; Corticosterone; Depression; Disease Models, Animal; Eating; Female; GABA-A Receptor Antagonists; Hindlimb Suspension; Male; Maze Learning; Mice; Receptors, GABA-A; Sex Factors; Swimming; Testosterone | 2017 |
Hemodynamic Changes Associated with Interictal Spikes Induced by Acute Models of Focal Epilepsy in Rats: A Simultaneous Electrocorticography and Near-Infrared Spectroscopy Study.
Topics: Animals; Bicuculline; Brain; Disease Models, Animal; Electrocorticography; Electroencephalography; Epilepsies, Partial; GABA-A Receptor Antagonists; Hemodynamics; Hemoglobins; Male; Neurovascular Coupling; Oxyhemoglobins; Penicillin G; Rats; Rats, Sprague-Dawley; Spectroscopy, Near-Infrared | 2017 |
Prolonged striatal disinhibition as a chronic animal model of tic disorders.
Topics: Action Potentials; Animals; Bicuculline; Catheters, Indwelling; Chronic Disease; Corpus Striatum; Disease Models, Animal; Female; Functional Laterality; Infusion Pumps, Implantable; Neurons; Rats, Long-Evans; Tic Disorders; Time Factors | 2017 |
Differential dietary ethanol intake and blood ethanol levels in adolescent and adult rats: effects on anxiety-like behavior and seizure thresholds.
Topics: Aging; Alcohol Drinking; Alcohol Withdrawal Seizures; Animals; Anxiety; Behavior, Animal; Bicuculline; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Reflex; Ethanol; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Seizures; Social Behavior | 2008 |
Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Bicuculline; Diazepam; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; GABA Modulators; Imidazoles; Male; Pyridines; Rats; Rats, Inbred F344; Seizures; Zolpidem | 2008 |
Fos expression following activation of the ventral pallidum in normal rats and in a model of Parkinson's Disease: implications for limbic system and basal ganglia interactions.
Topics: Animals; Basal Ganglia; Bicuculline; Brain; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; Globus Pallidus; Immunohistochemistry; Limbic System; Male; Microinjections; N-Methylaspartate; Neurons; Oncogene Proteins v-fos; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Sympatholytics | 2008 |
Differential involvement of GABA system in mediating behavioral and neurochemical effect of acupuncture in ethanol-withdrawn rats.
Topics: Acupuncture; Acupuncture Points; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Brain Chemistry; Disease Models, Animal; Dopamine; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Male; Morpholines; Motor Activity; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Time Factors | 2008 |
Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Drug Administration Schedule; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Pain; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Time Factors | 2008 |
Long-term potentiation-like facilitation through GABAA receptor blockade in the mouse dentate gyrus in vivo.
Topics: Alzheimer Disease; Animals; Bicuculline; Dentate Gyrus; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Humans; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; tau Proteins | 2008 |
The role of GABA and anxiety in the reconsolidation of conditioned fear.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Bicuculline; Conditioning, Psychological; Disease Models, Animal; Electroshock; Fear; Freezing Reaction, Cataleptic; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Maze Learning; Memory; Midazolam; Rats; Rats, Sprague-Dawley; Stress, Psychological; Time Factors | 2008 |
Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Bicuculline; Disease Models, Animal; Disease Susceptibility; Edema; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; Exons; Female; GABA Antagonists; Hippocampus; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; In Vitro Techniques; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium; Potassium Channel Blockers; Quaternary Ammonium Compounds; Reaction Time; Rett Syndrome; Sex Factors | 2009 |
Stimulation of delta opioid receptors located in substantia nigra reticulata but not globus pallidus or striatum restores motor activity in 6-hydroxydopamine lesioned rats: new insights into the role of delta receptors in parkinsonism.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzamides; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hindlimb Suspension; Male; Microdialysis; Motor Activity; Oxidopamine; Parkinsonian Disorders; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substantia Nigra; Thiophenes; Time Factors | 2008 |
Abnormal network activity in a targeted genetic model of human double cortex.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Persistent working memory dysfunction following traumatic brain injury: evidence for a time-dependent mechanism.
Topics: Analysis of Variance; Animals; Bicuculline; Brain Injuries; Dendritic Spines; Disease Models, Animal; GABA Antagonists; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Neurons; Prefrontal Cortex; Psychomotor Performance; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Reaction Time; Silver Staining; Time Factors | 2009 |
Enhancement of inhibitory synaptic transmission in large aspiny neurons after transient cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Biophysics; Biotin; Calcium; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Ion Channel Gating; Ischemic Attack, Transient; Male; Membrane Potentials; Muscimol; Neurons; Ovulation Inhibition; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Time Factors | 2009 |
Corticofugal outputs facilitate acute, but inhibit chronic pain in rats.
Topics: Analysis of Variance; Animals; Bicuculline; Chronic Disease; Disease Models, Animal; Freund's Adjuvant; Functional Laterality; GABA Agonists; GABA Antagonists; Hot Temperature; Male; Muscimol; Neural Pathways; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Spinothalamic Tracts; Thalamic Nuclei; Time Factors | 2009 |
Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoisobutyric Acids; Animals; Bicuculline; Disease Models, Animal; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamine; In Vitro Techniques; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2009 |
Cholecystokinin-8 sulfate modulates the anticonvulsant efficacy of vigabatrin in an experimental model of partial complex epilepsy in the rat.
Topics: Analysis of Variance; Animals; Anticonvulsants; Bicuculline; Convulsants; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Electric Stimulation; Epilepsy, Complex Partial; Evoked Potentials; Male; Nootropic Agents; Rats; Rats, Wistar; Reaction Time; Sincalide; Vigabatrin | 2009 |
Participation of GABA-ergic system in epileptogenic activity induced by teicoplanin in mice.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Brain; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Nipecotic Acids; Oximes; Phosphinic Acids; Pyridines; Teicoplanin | 2009 |
Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia.
Topics: Analgesics, Opioid; Animals; Bicuculline; Blood Pressure; Capsaicin; Disease Models, Animal; Drug Resistance; Extracellular Signal-Regulated MAP Kinases; GABA Antagonists; Glycine; Hyperalgesia; Male; Morphine; Nonlinear Dynamics; Oncogene Proteins v-fos; Pain Measurement; Pain Threshold; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Strychnine | 2009 |
Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex.
Topics: Animals; Bicuculline; Cerebellum; Cerebral Cortex; Cognition; Cyclic GMP; Disease Models, Animal; GABA Antagonists; GABA-A Receptor Antagonists; Hyperammonemia; Male; Maze Learning; Rats; Rats, Wistar; Receptors, GABA-A | 2009 |
Similar effects of lamotrigine and phenytoin against cortical epileptic foci in immature rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Partial; Lamotrigine; Male; Motor Cortex; Phenytoin; Rats; Rats, Wistar; Time Factors; Triazines | 2010 |
Functional and neuroreceptor imaging of the brain in bicuculline-induced dystonic rats.
Topics: Animals; Autoradiography; Bicuculline; Brain; Disease Models, Animal; Dystonia; Efferent Pathways; Glucose; Male; Radioisotopes; Radionuclide Imaging; Rats; Rats, Wistar; Receptor, Adenosine A1 | 2009 |
Dysfunction of the subthalamic nucleus induces behavioral and movement disorders in monkeys.
Topics: Animals; Behavior, Animal; Bicuculline; Chlorocebus aethiops; Disease Models, Animal; Functional Laterality; GABA Agents; Globus Pallidus; Male; Microinjections; Movement Disorders; Muscimol; Reaction Time; Stereotyped Behavior; Subthalamic Nucleus | 2009 |
Blocking GABA-A receptors in the medial septum enhances hippocampal acetylcholine release and behavior in a rat model of diencephalic amnesia.
Topics: Acetylcholine; Amnesia; Animals; Behavior, Animal; Bicuculline; Chromatography, High Pressure Liquid; Disease Models, Animal; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; Male; Rats; Rats, Sprague-Dawley | 2009 |
The neurophysiological correlates of motor tics following focal striatal disinhibition.
Topics: Animals; Basal Ganglia; Bicuculline; Brain Mapping; Corpus Striatum; Disease Models, Animal; Electroencephalography; Electromyography; GABA Antagonists; Macaca fascicularis; Microinjections; Motor Cortex; Neural Inhibition; Signal Processing, Computer-Assisted; Tic Disorders | 2009 |
GABAergic modulation of the 40 Hz auditory steady-state response in a rat model of schizophrenia.
Topics: Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Evoked Potentials, Auditory; GABA Agonists; GABA Antagonists; Hippocampus; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Temporal Lobe | 2010 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; GABA Agonists; GABA Antagonists; Hypertension; Infusion Pumps, Implantable; Male; Microinjections; Muscimol; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Time Factors; Up-Regulation | 2009 |
Zolpidem increases bladder capacity and decreases urine excretion in rats.
Topics: Aldosterone; Animals; Bicuculline; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; GABA Agonists; GABA Antagonists; Infarction, Middle Cerebral Artery; Injections, Intravenous; Pyridines; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Rats, Wistar; Time Factors; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics; Zolpidem | 2010 |
Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats.
Topics: Anacardiaceae; Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Epilepsy; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2010 |
Behavioral deficit and decreased GABA receptor functional regulation in the cerebellum of epileptic rats: effect of Bacopa monnieri and bacoside A.
Topics: Animals; Anticonvulsants; Behavioral Symptoms; Bicuculline; Carbamazepine; Cerebellum; Disease Models, Animal; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Phytotherapy; Pilocarpine; Plant Preparations; Protein Binding; Rats; Rats, Wistar; Receptors, GABA; Saponins; Triterpenes; Tritium | 2010 |
N-methyl-D-aspartate, hyperpolarization-activated cation current (Ih) and gamma-aminobutyric acid conductances govern the risk of epileptogenesis following febrile seizures in rat hippocampus.
Topics: Animals; Animals, Newborn; Bicuculline; Biophysics; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hyperthermia, Induced; In Vitro Techniques; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Seizures, Febrile; Statistics, Nonparametric; Synapses | 2010 |
Epileptic seizures increase circulating endothelial cells in peripheral blood as early indicators of cerebral vascular damage.
Topics: Animals; Apoptosis; Bicuculline; CD146 Antigen; Cell Communication; Cell Proliferation; Cells, Cultured; Cerebral Arteries; Cerebrovascular Disorders; Convulsants; Disease Models, Animal; Endothelium, Vascular; Epilepsy; Female; Immunophenotyping; Male; Microvessels; Predictive Value of Tests; Swine | 2010 |
[Bicuculline inhibits airway remodeling in a murine model of chronic asthma].
Topics: Airway Remodeling; Animals; Asthma; Bicuculline; Disease Models, Animal; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred BALB C | 2010 |
Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A.
Topics: Animals; Anticonvulsants; Bacopa; Basal Ganglia; Behavior, Animal; Bicuculline; Binding, Competitive; Carbamazepine; Disease Models, Animal; Down-Regulation; GABA Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA-A; Recognition, Psychology; RNA, Messenger; Saponins; Status Epilepticus; Triterpenes | 2010 |
Investigation of linear coupling between single-event blood flow responses and interictal discharges in a model of experimental epilepsy.
Topics: Animals; Bicuculline; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; Evoked Potentials; GABA Antagonists; Image Processing, Computer-Assisted; Laser-Doppler Flowmetry; Linear Models; Magnetic Resonance Imaging; Male; Oxygen; Rats; Rats, Wistar | 2010 |
Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling.
Topics: Animals; Bicuculline; CA1 Region, Hippocampal; Calcineurin; Calcineurin Inhibitors; Chronic Disease; Cyclic Nucleotide-Gated Cation Channels; Dendrites; Disease Models, Animal; Down-Regulation; Epilepsy; In Vitro Techniques; Magnesium Compounds; Male; Membrane Potentials; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Seizures | 2010 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesia; Anesthetics, Intravenous; Animals; Atropine; Baclofen; Bicuculline; Biophysics; Dioxanes; Disease Models, Animal; Electroacupuncture; GABA Agents; Male; Methysergide; Models, Biological; Multivariate Analysis; Naloxone; Narcotic Antagonists; Pain; Pain Management; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Serotonin Antagonists; Tail; Thiopental; Time Factors | 2011 |
The effect of intra-locus coeruleus injection of 17beta-estradiol on inflammatory pain modulation in male rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Formaldehyde; Fulvestrant; Inflammation; Locus Coeruleus; Male; Microinjections; Pain; Rats; Rats, Sprague-Dawley; Valine | 2010 |
Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice.
Topics: Animals; Bicuculline; Disease Models, Animal; Glycine; Hot Temperature; Hyperalgesia; Injections; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Muscimol; Pain; Pain Threshold; Receptors, GABA; Receptors, Glycine; Taurine | 2010 |
GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Clonixin; Conditioning, Classical; Diazepam; Disease Models, Animal; Electroencephalography; Evoked Potentials, Auditory; Fear; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Male; Maze Learning; Microinjections; Muscimol; Neurons; Prostaglandin Antagonists; Rats; Rats, Wistar; Sensory Gating; Statistics as Topic | 2010 |
Enhanced excitatory and reduced inhibitory synaptic transmission contribute to persistent pain-induced neuronal hyper-responsiveness in anterior cingulate cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Analysis of Variance; Animals; Bee Venoms; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gyrus Cinguli; Male; Neural Inhibition; Neurons; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin | 2010 |
The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; CA3 Region, Hippocampal; Disease Models, Animal; Electrodes; Epilepsy; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Mice; Mice, Inbred C57BL; Microarray Analysis; Motion Pictures; Piperazines; Potassium Channel Blockers; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Software; Somatosensory Cortex | 2011 |
Orexinergic system and pathophysiology of epilepsy.
Topics: Animals; Bicuculline; CA1 Region, Hippocampal; Disease Models, Animal; Epilepsy; Intracellular Signaling Peptides and Proteins; Male; Neuropeptides; Orexin Receptors; Orexins; Rats; Receptors, G-Protein-Coupled; Receptors, Neuropeptide | 2010 |
Abnormal synaptic plasticity in basolateral amygdala may account for hyperactivity and attention-deficit in male rat exposed perinatally to low-dose bisphenol-A.
Topics: Air Pollutants, Occupational; Amygdala; Animals; Attention Deficit Disorder with Hyperactivity; Benzazepines; Benzhydryl Compounds; Bicuculline; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Long-Term Potentiation; Male; Muscimol; Neuronal Plasticity; Phenols; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Anticonvulsant profile of the alkaloids (+)-erythravine and (+)-11-α-hydroxy-erythravine isolated from the flowers of Erythrina mulungu Mart ex Benth (Leguminosae-Papilionaceae).
Topics: Animals; Anticonvulsants; Bicuculline; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Flowers; Heterocyclic Compounds, 4 or More Rings; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Reaction Time; Seizures | 2011 |
The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease.
Topics: Action Potentials; Analysis of Variance; Animals; Bicuculline; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Indoles; Male; Oxidopamine; Parkinson Disease; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin Agents; Statistics, Nonparametric; Substantia Nigra; Tropisetron; Tyrosine 3-Monooxygenase | 2011 |
Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release.
Topics: Analysis of Variance; Animals; Bicuculline; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Free Radical Scavengers; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Male; Mice; Neuralgia; Neurons; Reactive Oxygen Species; Spinal Cord; Spinal Nerves; tert-Butylhydroperoxide; Time Factors | 2011 |
Stimulation of the prelimbic cortex differentially modulates neuroendocrine responses to psychogenic and systemic stressors.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Bicuculline; Corticosterone; Disease Models, Animal; GABA-A Receptor Antagonists; Hypoxia; Male; Neurons; Oncogene Proteins v-fos; Paraventricular Hypothalamic Nucleus; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2011 |
Differential effects of mGluR7 and mGluR8 activation on pain-related synaptic activity in the amygdala.
Topics: Adjuvants, Immunologic; Amygdala; Animals; Arthritis; Benzhydryl Compounds; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Potentials | 2011 |
Reduced striatal acetylcholine efflux in the R6/2 mouse model of Huntington's disease: an examination of the role of altered inhibitory and excitatory mechanisms.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Bicuculline; Cholinergic Neurons; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Humans; Huntingtin Protein; Huntington Disease; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Transgenic; Motor Skills; Nerve Degeneration; Nerve Tissue Proteins; Neural Inhibition; Nuclear Proteins; Synaptic Transmission | 2011 |
Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors.
Topics: Action Potentials; Animals; Arthritis, Experimental; Benzoates; Bicuculline; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Methoxyhydroxyphenylglycol; Neurons; Pain; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 2011 |
Enhanced GABAergic tone in the ventral pallidum: memory of unpleasant experiences?
Topics: Animals; Behavior, Animal; Bicuculline; Depression; Disease Models, Animal; Enzyme Inhibitors; GABA-A Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Memory; Microdialysis; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Vigabatrin | 2011 |
Progesterone and allopregnanolone exacerbate hypoxic-ischemic brain injury in immature rats.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Brain; Brain Injuries; Disease Models, Animal; Drug Administration Routes; Functional Laterality; GABA-A Receptor Antagonists; Hypoxia-Ischemia, Brain; Pregnanolone; Progesterone; Rats; Rats, Wistar; Time Factors | 2012 |
Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.
Topics: Actins; Aggression; Animals; Behavior, Animal; Bicuculline; Body Weight; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Embryo, Mammalian; Endophenotypes; Exploratory Behavior; Female; GABA Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Genotype; Glial Fibrillary Acidic Protein; Glycine; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Inhibition, Psychological; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Membrane Potentials; Memory, Short-Term; Mental Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Muscle Strength; Mutation; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Picrotoxin; Post-Synaptic Density; Psychomotor Performance; Receptors, AMPA; Receptors, Kainic Acid; Recognition, Psychology; Rotarod Performance Test; Sialoglycoproteins; Statistics, Nonparametric; Time Factors | 2011 |
Neuronostatin induces hyperalgesia in formalin test in mice.
Topics: Analysis of Variance; Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; GABA-A Receptor Antagonists; Hyperalgesia; Injections, Intraventricular; Male; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred Strains; Pain Measurement; Pain Threshold; Peptide Fragments; Somatostatin; Time Factors | 2012 |
Spatiotemporal organization and thalamic modulation of seizures in the mouse medial thalamic-anterior cingulate slice.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Biological Clocks; Calcium; Corpus Callosum; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes; Gyrus Cinguli; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscimol; Neural Pathways; Seizures; Thalamus | 2011 |
The mechanisms of antihyperalgesic effect of topiramate in a rat model of inflammatory hyperalgesia.
Topics: Analgesics; Animals; Bicuculline; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Hyperalgesia; Inflammation; Male; Naloxone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Receptors, Opioid; Topiramate; Yohimbine | 2013 |
Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Cognition Disorders; Disease Models, Animal; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; F-Box Proteins; GABA-A Receptor Antagonists; Immunoprecipitation; In Vitro Techniques; Male; Nedd4 Ubiquitin Protein Ligases; Neuropsychological Tests; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Recognition, Psychology; Restraint, Physical; RNA, Small Interfering; Stress, Psychological; Ubiquitin-Protein Ligases | 2012 |
An antagonist of GABA-B receptors potentiates activity of cortical epileptic foci.
Topics: Animals; Bicuculline; Brain Waves; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-B; Time Factors | 2012 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; Bicuculline; Disease Models, Animal; Dopamine Antagonists; Electrodes; Female; GABA Antagonists; Hyperalgesia; Ketanserin; Methysergide; Neuralgia; Pain Measurement; Pain Threshold; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Sulpiride; Time Factors; Transcutaneous Electric Nerve Stimulation | 2012 |
Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Bicuculline; Cyproheptadine; Disease Models, Animal; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Maze Learning; Methysergide; Mice; Neurotransmitter Agents; Phenoxybenzamine; Prazosin; Sermorelin; Swimming | 2012 |
Behavioral and EEG effects of GABAergic manipulation of the nigro-tectal pathway in the Wistar audiogenic rat (WAR) strain II: an EEG wavelet analysis and retrograde neuronal tracer approach.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Bicuculline; Brain Waves; Disease Models, Animal; Electric Stimulation; Epilepsy, Reflex; GABA Agents; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Pathways; Rats; Rats, Mutant Strains; Rats, Wistar; Stilbamidines; Substantia Nigra; Superior Colliculi | 2012 |
Inhibitory control of nociceptive responses of trigeminal spinal nucleus cells by somatosensory corticofugal projection in rat.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Biophysics; Capsaicin; Constriction; Disease Models, Animal; Electric Stimulation; Female; GABA-A Receptor Antagonists; Glutamic Acid; Glycine Agents; Hyperalgesia; Iontophoresis; Male; Neural Inhibition; Neuralgia; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Strychnine; Time Factors; Trigeminal Nucleus, Spinal | 2012 |
Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat.
Topics: Action Potentials; Amygdala; Animals; Bicuculline; Carrageenan; Chromones; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; GABA Antagonists; Gene Expression; Glycine; Male; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Pain; Physical Stimulation; Prefrontal Cortex; Pyramidal Cells; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2013 |
Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide.
Topics: Amniotic Fluid; Animals; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Lipopolysaccharides; Mice; Muscimol; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Placenta; Pregnancy; Premature Birth; Receptors, GABA-A; Uterine Contraction | 2013 |
Reduction of nitric oxide-mediated γ-amino butyric acid release in rostral ventrolateral medulla is involved in superoxide-induced sympathoexcitation of hypertensive rats.
Topics: Animals; Arterial Pressure; Bicuculline; Cyclic N-Oxides; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Kidney; Kynurenic Acid; Male; Medulla Oblongata; Microdialysis; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Superoxides; Sympathetic Nervous System; Time Factors | 2012 |
Superior colliculus mediates cervical dystonia evoked by inhibition of the substantia nigra pars reticulata.
Topics: Analysis of Variance; Animals; Bicuculline; Disease Models, Animal; Drug Administration Routes; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Head Movements; Macaca mulatta; Magnetic Resonance Imaging; Male; Movement; Muscimol; Postural Balance; Sensation Disorders; Substantia Nigra; Superior Colliculi; Torticollis | 2012 |
The associative and limbic thalamus in the pathophysiology of obsessive-compulsive disorder: an experimental study in the monkey.
Topics: Animals; Anterior Thalamic Nuclei; Behavior, Animal; Bicuculline; Deep Brain Stimulation; Disease Models, Animal; GABA-A Receptor Antagonists; Macaca mulatta; Mediodorsal Thalamic Nucleus; Muscimol; Obsessive-Compulsive Disorder | 2012 |
Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient.
Topics: Animals; Arterial Pressure; Bicuculline; Disease Models, Animal; Dorsomedial Hypothalamic Nucleus; GABA-A Receptor Antagonists; Glaucoma; Intracranial Pressure; Intraocular Pressure; Male; Microinjections; Rats; Rats, Sprague-Dawley | 2012 |
Towards a primate model of Gilles de la Tourette syndrome: anatomo-behavioural correlation of disorders induced by striatal dysfunction.
Topics: Afferent Pathways; Animals; Axons; Behavior, Animal; Bicuculline; Chlorocebus aethiops; Disease Models, Animal; Efferent Pathways; GABA Antagonists; Macaca fascicularis; Macaca mulatta; Male; Microinjections; Neostriatum; Stereotyped Behavior; Tourette Syndrome | 2013 |
Anticonvulsant action of indazole.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Indazoles; Male; Mice; Pentylenetetrazole; Phenytoin; Seizures; Strychnine | 2013 |
Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-aminobutyric acid mechanisms.
Topics: Animals; Atropine; Bicuculline; Cholinergic Agents; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; GABA Agents; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Indans; Male; Mecamylamine; Neuralgia; Nicotinic Antagonists; Organophosphorus Compounds; Parasympatholytics; Peripheral Nerve Injuries; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2013 |
Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome.
Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Waves; Disease Models, Animal; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Hippocampus; Kainic Acid; Methyl-CpG-Binding Protein 2; Mice; Nerve Net; Neurons; Potassium Channel Blockers; Rett Syndrome; Seizures | 2013 |
Blunted endogenous GABA-mediated inhibition in the hypothalamic paraventricular nucleus of rats with streptozotocin-induced diabetes.
Topics: Animals; Bicuculline; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Microinjections; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Streptozocin | 2013 |
Accumulation of GABAergic neurons, causing a focal ambient GABA gradient, and downregulation of KCC2 are induced during microgyrus formation in a mouse model of polymicrogyria.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Cell Count; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Embryo, Mammalian; Female; GABA-A Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamate Decarboxylase; K Cl- Cotransporters; Male; Malformations of Cortical Development; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitrogen; Symporters | 2014 |
Maternal separation increases GABA(A) receptor-mediated modulation of norepinephrine release in the hippocampus of a rat model of ADHD, the spontaneously hypertensive rat.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Bicuculline; Disease Models, Animal; GABA-A Receptor Antagonists; Gene Expression Regulation; Glutamic Acid; Hippocampus; Locus Coeruleus; Male; Maternal Deprivation; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-A; Tritium | 2013 |
Involvement of GABAergic system in regulation of the anxiolytic- and antidepressant-like effects of Scrophularia striata extract in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Bicuculline; Brain; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Maze Learning; Muscimol; Plant Extracts; Rats; Rats, Wistar; Receptors, GABA-A; Scrophularia; Swimming | 2013 |
Compromised hemodynamic response in amyloid precursor protein transgenic mice.
Topics: Acetazolamide; Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bicuculline; Body Weight; Brain; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; GABA Antagonists; GABA-A Receptor Antagonists; Hemodynamics; Humans; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Phenotype | 2002 |
Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex.
Topics: Animals; Bicuculline; Carmustine; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Litter Size; Patch-Clamp Techniques; Pregnancy; Pyramidal Cells; Rats; Receptors, GABA | 2002 |
An anticonvulsant profile of the ketogenic diet in the rat.
Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Bicuculline; Convulsants; Dietary Fats; Disease Models, Animal; Electroencephalography; Male; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Strychnine; Survival Rate; Time Factors | 2002 |
Medulloblastoma growth inhibition by hedgehog pathway blockade.
Topics: Animals; Antineoplastic Agents; Bicuculline; Cell Differentiation; Cell Division; Cerebellar Neoplasms; Disease Models, Animal; Hedgehog Proteins; Humans; Medulloblastoma; Membrane Proteins; Mice; Mice, Nude; Patched Receptors; Receptors, Cell Surface; Signal Transduction; Trans-Activators; Tumor Cells, Cultured | 2002 |
Suppression of epileptiform activity by GABA(B) receptors in wild type and weaver hippocampus 'in vitro'.
Topics: Animals; Baclofen; Bicuculline; Crosses, Genetic; Disease Models, Animal; Epilepsy; Female; GABA Agonists; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Mice, Neurologic Mutants; Neurons; Pyramidal Cells; Receptors, GABA-B | 2003 |
Increased dendritic excitability in hippocampal ca1 in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis.
Topics: Action Potentials; Animals; Bicuculline; Dendrites; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Kainic Acid; Male; Neural Inhibition; Neural Pathways; Perforant Pathway; Rats; Rats, Long-Evans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2003 |
Role of the superior colliculus and the intercollicular nucleus in the brainstem seizure circuitry of the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Bicuculline; Brain Stem; Disease Models, Animal; Epilepsy; Female; Inferior Colliculi; Male; Rats; Rats, Mutant Strains; Seizures; Superior Colliculi | 2003 |
Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Modulators; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; GABA Antagonists; Genetic Predisposition to Disease; Hippocampus; Kainic Acid; Limbic System; Mice; Mice, Knockout; Neurons; Neurotoxins; Polyunsaturated Alkamides; Seizures | 2003 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-Acetyltransferase; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Muscarinic Antagonists; Muscimol; Muscle Tonus; N-Methylaspartate; Neural Inhibition; Picrotoxin; Stimulation, Chemical | 2003 |
Bicarbonate-dependent depolarizing potentials in pyramidal cells and interneurons during epileptiform activity.
Topics: Animals; Animals, Newborn; Bicarbonates; Bicuculline; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Electric Stimulation; Epilepsy; Ethoxzolamide; Evoked Potentials; GABA Antagonists; In Vitro Techniques; Interneurons; Magnesium; Male; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar | 2003 |
Diazepam prophylaxis for bicuculline-induced seizures: a rat dose-response model.
Topics: Action Potentials; Animals; Bicuculline; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Seizures | 2004 |
Effect of zinc in ischemic brain injury in an embolic model of stroke in rats.
Topics: Animals; Bicuculline; Brain Ischemia; Disease Models, Animal; Drug Synergism; Intracranial Embolism; Male; Rats; Rats, Sprague-Dawley; Stroke; Zinc | 2004 |
Effects of rubral microinjections of muscimol and bicuculline in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; GABA Agonists; GABA Antagonists; Microinjections; Models, Genetic; Motor Activity; Muscimol; Reaction Time; Red Nucleus; Time Factors | 2004 |
Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hyperalgesia; Neural Inhibition; Neural Pathways; Pain; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Spinal Cord Injuries; Touch; Wounds, Nonpenetrating | 2004 |
Excitability of CA1 neurons in the model of malformation-associated epilepsy.
Topics: Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Epilepsy; Evoked Potentials; Female; GABA Antagonists; Hippocampus; Male; Methylazoxymethanol Acetate; Neurons; Potassium Acetate; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Relative changes in cerebral blood flow and neuronal activity in local microdomains during generalized seizures.
Topics: Animals; Bicuculline; Brain; Cerebrovascular Circulation; Convulsants; Disease Models, Animal; Epilepsy, Absence; Female; Laser-Doppler Flowmetry; Microelectrodes; Neurons; Rats; Rats, Inbred Strains; Vibrissae | 2004 |
Changes in response properties and receptive fields of spinal dorsal horn neurons in rats after surgical incision in hairy skin.
Topics: Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Electrophysiology; GABA Antagonists; Hair; Hyperalgesia; Male; Mechanoreceptors; Microelectrodes; Pain Threshold; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Skin Transplantation | 2005 |
AMPA receptor desensitization as a determinant of vulnerability to focally evoked status epilepticus.
Topics: Animals; Behavior, Animal; Benzothiadiazines; Bicuculline; Carbachol; Cerebral Cortex; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Excitatory Amino Acid Agonists; GABA Antagonists; Herpesviridae Infections; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Status Epilepticus | 2005 |
Cellular and network properties of the subiculum in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Bicuculline; Cell Count; Dendrites; Dendritic Spines; Disease Models, Animal; Epilepsy, Temporal Lobe; Fluoresceins; GABA Antagonists; Hippocampus; In Vitro Techniques; Lysine; Membrane Potentials; Muscarinic Agonists; Nerve Net; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Rats; Rats, Wistar; Staining and Labeling | 2005 |
Actions at GABA(A) receptors in the hippocampus may mediate some antiseizure effects of progestins.
Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; gamma-Aminobutyric Acid; Hippocampus; Isotopes; Ovariectomy; Pentylenetetrazole; Progestins; Rats; Rats, Long-Evans; Reaction Time; Receptors, GABA-A; Seizures; Tissue Distribution | 2005 |
Correlation between shaking behaviors and seizure severity in five animal models of convulsive seizures.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; Electric Stimulation; Electroencephalography; Functional Laterality; GABA Antagonists; Hippocampus; Kindling, Neurologic; Male; Microscopy, Interference; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Rats, Wistar; Scopolamine; Seizures; Stereotaxic Techniques; Time Factors | 2005 |
Modification of epileptiform discharges in neocortical neurons following glutamate uptake inhibition.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Bicuculline; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Freezing; Glutamates; Hippocampus; In Vitro Techniques; Neocortex; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
GABA synapses and the rapid loss of inhibition to dentate gyrus granule cells after brief perforant-path stimulation.
Topics: Animals; Bicuculline; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Perforant Pathway; Rats; Rats, Wistar; Receptors, GABA-A; Status Epilepticus; Synaptic Transmission | 2005 |
Anticonvulsant action of GABA in the high potassium-low magnesium model of ictogenesis in the neonatal rat hippocampus in vivo and in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Lipoproteins; Magnesium; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Pyridazines; Rats; Seizures | 2005 |
Protection with estradiol in developmental models of apoptotic neurodegeneration.
Topics: Animals; Animals, Newborn; Apoptosis; Bicuculline; Blotting, Western; Brain; Caenorhabditis elegans Proteins; Cell Count; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Extracellular Signal-Regulated MAP Kinases; GABA Antagonists; Hypoxia; Immunohistochemistry; In Situ Nick-End Labeling; Membrane Potentials; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Phenobarbital; Phenytoin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, GABA-A; Silver Staining; Tamoxifen | 2005 |
5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain.
Topics: Anesthetics; Animals; Behavior, Animal; Bicuculline; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Estranes; Female; GABA Antagonists; Hot Temperature; Hyperalgesia; Neuralgia; Nitriles; Oxidation-Reduction; Pain Measurement; Pain Threshold; Pregnanediones; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Steroids; Time Factors; Touch; Treatment Outcome | 2005 |
Divergent effects of bicuculline and picrotoxin on ketamine-induced apneustic breathing.
Topics: Animals; Apnea; Bicuculline; Blood Pressure; Cats; Disease Models, Animal; GABA Antagonists; GABA-A Receptor Antagonists; Inhalation; Injections, Intravenous; Ketamine; Phrenic Nerve; Picrotoxin; Receptors, GABA-A; Respiratory Mechanics | 2005 |
Propagation dynamics of epileptiform activity acutely induced by bicuculline in the hippocampal-parahippocampal region of the isolated Guinea pig brain.
Topics: Action Potentials; Acute Disease; Animals; Bicuculline; Brain Mapping; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Electrophysiology; Epilepsy; Evoked Potentials; Guinea Pigs; Hippocampus; Humans; In Vitro Techniques; Neural Pathways; Parahippocampal Gyrus | 2005 |
Impaired synaptic plasticity in a rat model of tuberous sclerosis.
Topics: Animals; Animals, Genetically Modified; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Synapses; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2006 |
Facilitation of granule cell epileptiform activity by mossy fiber-released zinc in the pilocarpine model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Bicuculline; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Mossy Fibers, Hippocampal; Neurons; Perforant Pathway; Pilocarpine; Potassium; Rats; Rats, Sprague-Dawley; Zinc | 2006 |
A brief period of epileptiform activity strengthens excitatory synapses in the rat hippocampus in vitro.
Topics: Animals; Bicuculline; Cells, Cultured; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Humans; In Vitro Techniques; Interneurons; Long-Term Potentiation; Memory Disorders; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2006 |
Reeler homozygous mice exhibit enhanced susceptibility to epileptiform activity.
Topics: Animals; Bicuculline; Disease Models, Animal; Electroshock; Epilepsy; Genetic Predisposition to Disease; Hippocampus; Homozygote; Humans; In Vitro Techniques; Kindling, Neurologic; Male; Mice; Mice, Neurologic Mutants; Neocortex; Nervous System Malformations; Phenotype | 2006 |
Laminar analysis of initiation and spread of epileptiform discharges in three in vitro models.
Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Convulsants; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; GABA Antagonists; Interneurons; Magnesium; Male; Neocortex; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Proto-Oncogene Proteins c-fos; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission | 2006 |
Effect of cyclooxygenase-2 (COX-2) inhibitors in various animal models (bicuculline, picrotoxin, maximal electroshock-induced convulsions) of epilepsy with possible mechanism of action.
Topics: Animals; Bicuculline; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Muscimol; Picrotoxin; Seizures | 2006 |
Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Lethal Dose 50; Male; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Persea; Phytotherapy; Picrotoxin; Plant Extracts; Plant Leaves; Seizures | 2006 |
Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebrospinal Fluid; Cryotherapy; Disease Models, Animal; Electrodes; Electroencephalography; Evoked Potentials; Hippocampus; Limbic System; Male; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission | 2006 |
GABA(A) receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: functional implications.
Topics: Action Potentials; Afferent Pathways; Animals; Basal Ganglia; Bicuculline; Cerebral Cortex; Disease Models, Animal; Epilepsy, Absence; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Intralaminar Thalamic Nuclei; Neural Inhibition; Rats; Rats, Wistar; Receptors, GABA-A; Substantia Nigra; Synaptic Transmission; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2006 |
Anticonvulsant and anxiolytic activity of FrPbAII, a novel GABA uptake inhibitor isolated from the venom of the social spider Parawixia bistriata (Araneidae: Araneae).
Topics: Analysis of Variance; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Bicuculline; Choice Behavior; Diazepam; Disease Models, Animal; Drug Interactions; Hippocampus; Male; Maze Learning; Neuroprotective Agents; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Spider Venoms; Spiders; Substantia Nigra; Urea | 2006 |
Altered synaptic input and GABAB receptor function in spinal superficial dorsal horn neurons in rats with diabetic neuropathy.
Topics: Animals; Baclofen; Bicuculline; Diabetic Neuropathies; Disease Models, Animal; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Glutamic Acid; Glycine; Interneurons; Male; Neural Inhibition; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synapses; Synaptic Transmission | 2007 |
Locus coeruleus and neuronal plasticity in a model of focal limbic epilepsy.
Topics: Animals; Benzylamines; Bicuculline; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Limbic System; Locus Coeruleus; Male; Mossy Fibers, Hippocampal; Neuronal Plasticity; Neurotoxins; Norepinephrine; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Sodium Chloride; Status Epilepticus | 2006 |
Effects of postnatal caffeine exposure on seizure susceptibility in developing rats.
Topics: Age Factors; Aminophylline; Animals; Animals, Newborn; Behavior, Animal; Bicuculline; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Disease Susceptibility; Drug Interactions; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Seizures; Severity of Illness Index | 2007 |
Cerebroprotective effects of the CO-releasing molecule CORM-A1 against seizure-induced neonatal vascular injury.
Topics: Administration, Topical; Animals; Animals, Newborn; Bicuculline; Blood Pressure; Boranes; Bradykinin; Carbon Monoxide; Carbonates; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hemin; Injections, Intraperitoneal; Injections, Intravenous; Isoproterenol; Nitroprusside; Protective Agents; Seizures; Swine; Vasodilation; Vasodilator Agents | 2007 |
Activation of central adenosine A(2A) receptors enhances superior laryngeal nerve stimulation-induced apnea in piglets via a GABAergic pathway.
Topics: Adenosine; Animals; Animals, Newborn; Apnea; Bicuculline; Blood Pressure; Cisterna Magna; Disease Models, Animal; Drug Antagonism; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Injections, Intraventricular; Laryngeal Nerves; Phenethylamines; Phrenic Nerve; Receptor, Adenosine A2A; Swine | 2007 |
Alterations in GABA(A) receptor mediated inhibition in adjacent dorsal midline thalamic nuclei in a rat model of chronic limbic epilepsy.
Topics: Anesthetics, Local; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lysine; Male; Midline Thalamic Nuclei; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin | 2007 |
Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.
Topics: Adrenalectomy; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Male; Maze Learning; Muscimol; Oxazines; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time | 2007 |
Anticonvulsant property of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract.
Topics: Analysis of Variance; Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Mice; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures | 2008 |
GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Female; GABA Agonists; GABA Antagonists; Glutamate Decarboxylase; Injections, Spinal; Lumbar Vertebrae; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sacrum; Spinal Cord; Spinal Cord Injuries; Urinary Bladder, Overactive; Urodynamics | 2008 |
Extracellular hypothalamic gamma-aminobutyric acid (GABA) and L-glutamic acid concentrations in response to bicuculline in a genetic absence epilepsy rat model.
Topics: Animals; Bicuculline; Blood Pressure; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hypothalamus; Male; Rats; Rats, Wistar | 2008 |
Non-invasive imaging of epileptic seizures in vivo using photoacoustic tomography.
Topics: Acoustics; Animals; Bicuculline; Brain; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy; Humans; Image Processing, Computer-Assisted; Male; Rats; Rats, Sprague-Dawley; Tomography, Optical; Ultrasonography | 2008 |
GABAergic mechanisms are involved in the antihyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory hyperalgesia.
Topics: Analgesics, Non-Narcotic; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Oxcarbazepine; Pain Threshold; Rats; Rats, Wistar | 2008 |
Experimental hepatic encephalopathy: changes in the binding of gamma-aminobutyric acid.
Topics: Bicuculline; Binding, Competitive; Brain; Disease Models, Animal; Galactosamine; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Kinetics; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Time Factors | 1982 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Hypertension; Medulla Oblongata; Pentobarbital; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1984 |
Experimental choreoathetosis produced by injection of a gamma-aminobutyric acid antagonist into the lentiform nucleus in the monkey.
Topics: Animals; Athetosis; Bicuculline; Chorea; Disease Models, Animal; Macaca nemestrina; Putamen | 1984 |
Seizure-like spreading depression in immature rabbit hippocampus in vitro.
Topics: Animals; Bicuculline; Disease Models, Animal; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Membrane Potentials; Neuroglia; Penicillin G; Potassium Chloride; Rabbits | 1984 |
Seizure susceptibility in immature rats with micrencephaly induced by prenatal exposure to methylazoxymethanol acetate.
Topics: Age Factors; Animals; Bicuculline; Body Weight; Brain; Disease Models, Animal; Female; Humans; Infant, Newborn; Kainic Acid; Maternal-Fetal Exchange; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Wistar; Seizures | 1995 |
The role of glutamate and GABA receptors in the generation of dorsal root reflexes by acute arthritis in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Arthritis; Bicuculline; Disease Models, Animal; GABA-B Receptor Antagonists; Inflammation; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Spinal Nerve Roots; Time Factors | 1995 |
Interactions between opioid drugs and propofol in laboratory models of seizures.
Topics: Analgesics, Opioid; Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Kainic Acid; Meperidine; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Propofol; Seizures | 1995 |
Effects of treatment with imipramine and clonazepam on an animal model of panic disorder.
Topics: Analysis of Variance; Animals; Bicuculline; Clonazepam; Disease Models, Animal; Double-Blind Method; Hypothalamus, Middle; Imipramine; Male; Panic Disorder; Rats; Rats, Sprague-Dawley; Receptors, GABA | 1994 |
The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Pentylenetetrazole; Seizures | 1994 |
[The effect of the new amino acid-containing 1,4-dihydropyridine glutapyrone on penicillin-induced focal epileptic activity and convulsions induced by bicuculline and thiosemicarbazide].
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Dihydropyridines; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsies, Partial; Glutamates; Male; Mice; Mice, Inbred ICR; Penicillins; Rats; Rats, Wistar; Seizures; Semicarbazides | 1993 |
Morphological and functional consequences of chronic epilepsy in rat hippocampal slice cultures.
Topics: Animals; Bicuculline; Chronic Disease; Culture Techniques; Disease Models, Animal; Electrophysiology; Epilepsy; Hippocampus; Neurons; Picrotoxin; Rats | 1993 |
NG-nitro-L-arginine differentially affects glutamate- or kainate-induced seizures.
Topics: Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nitroarginine; Seizures | 1996 |
Review of the role of inhibitory neurons in chronic epileptic foci induced by intracerebral tetanus toxin.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cerebral Cortex; Disease Models, Animal; Epilepsy; Functional Laterality; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetanus Toxin | 1996 |
Epileptiform activity in the piriform cortex of the in vitro isolated guinea pig brain preparation.
Topics: Animals; Bicuculline; Brain; Cerebral Cortex; Disease Models, Animal; Epilepsy; Guinea Pigs; Neural Pathways; Olfactory Pathways; Receptors, GABA; Synaptic Transmission | 1996 |
Local perfusion of diazepam attenuates interictal and ictal events in the bicuculline model of epilepsy in rats.
Topics: Administration, Topical; Animals; Bicuculline; Cerebral Cortex; Diazepam; Disease Models, Animal; Double-Blind Method; Drug Delivery Systems; Electroencephalography; Epidural Space; Epilepsies, Partial; Epilepsy; Functional Laterality; Hippocampus; Male; Motor Cortex; Random Allocation; Rats | 1997 |
The cerebral hemisphere of the turtle in vitro. An experimental model with spontaneous interictal-like spikes for the study of epilepsy.
Topics: Animals; Bicuculline; Convulsants; Disease Models, Animal; Epilepsy; In Vitro Techniques; Membrane Potentials; Pyramidal Cells; Turtles | 1997 |
Antiepileptic effects of 20-hydroxyecdysone on convulsive seizures in spontaneously epileptic rats.
Topics: Administration, Oral; Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Ecdysterone; Epilepsy; Female; Male; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, GABA-A | 1997 |
Anticonvulsant and behavioural effects of bicuculline injected into the mesencephalic locomoter region of rats.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Electroshock; Epilepsy; Female; GABA Antagonists; Locomotion; Male; Mesencephalon; Microinjections; Movement; Muscle, Skeletal; Rats; Rats, Sprague-Dawley | 1997 |
Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Polypharmacy; Seizures; Vigabatrin | 1998 |
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease; Animals; Bicuculline; Brain; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Functional Laterality; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Lidocaine; Membrane Potentials; Reaction Time; Synaptic Transmission | 1999 |
Development of a model of status epilepticus in pigtailed macaque infant monkeys.
Topics: Animals; Animals, Newborn; Behavior, Animal; Bicuculline; Brain; Disease Models, Animal; Electric Stimulation; Electroencephalography; Electrophysiology; Entorhinal Cortex; Hippocampus; Injections; Macaca nemestrina; Magnetic Resonance Imaging; Status Epilepticus | 1999 |
Valproic acid intensifies epileptiform activity in the hippocampal pyramidal neurons.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Epilepsy; GABA Antagonists; Hippocampus; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Valproic Acid | 1999 |
Regional brain activation by bicuculline visualized by functional magnetic resonance imaging. Time-resolved assessment of bicuculline-induced changes in local cerebral blood volume using an intravascular contrast agent.
Topics: Animals; Bicuculline; Blood Volume; Brain; Cerebrovascular Circulation; Contrast Media; Disease Models, Animal; GABA Antagonists; Magnetic Resonance Imaging; Male; Nervous System Diseases; Rats; Rats, Inbred SHR | 2000 |
Free radical production correlates with cell death in an in vitro model of epilepsy.
Topics: Action Potentials; Aniline Compounds; Animals; Antioxidants; Bicuculline; Calcium; Cell Death; Disease Models, Animal; Epilepsy; Fluorescent Dyes; Free Radicals; GABA Antagonists; Glutathione; Hippocampus; Microscopy, Fluorescence; Nerve Degeneration; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Rhodamines; Vitamin E; Xanthenes | 2000 |
P rats develop physical dependence on alcohol via voluntary drinking: changes in seizure thresholds, anxiety, and patterns of alcohol drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Anxiety; Bicuculline; Convulsants; Disease Models, Animal; Rats; Seizures; Substance Withdrawal Syndrome | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Dehydroepiandrosterone sulfate is neuroprotective in a reversible spinal cord ischemia model: possible involvement of GABA(A) receptors.
Topics: Animals; Behavior, Animal; Bicuculline; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Intravenous; Male; Neuroprotective Agents; Paraplegia; Rabbits; Receptors, GABA-A; Recovery of Function; Spinal Cord Ischemia | 2000 |
Morphological plasticity in an infant monkey model of temporal lobe epilepsy.
Topics: Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Temporal Lobe; Hippocampus; Macaca nemestrina; Magnetic Resonance Imaging; Mossy Fibers, Hippocampal; Neuronal Plasticity; Status Epilepticus; Temporal Lobe | 2000 |
Functional connections and epileptic spread between hippocampus, entorhinal cortex and amygdala in a modified horizontal slice preparation of the rat brain.
Topics: Action Potentials; Amygdala; Animals; Bicuculline; Denervation; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2000 |
Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation.
Topics: Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Antioxidants; Benzodiazepinones; Bicuculline; Convulsants; Depression; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Flumazenil; GABA Agents; Immobilization; Isoquinolines; Male; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, GABA-A; Swimming; Time Factors | 2000 |
Contribution of GABA(A) and GABA(B) receptors to thalamic neuronal activity during spontaneous absence seizures in rats.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Linear Models; Male; Neurons; Phosphinic Acids; Propanolamines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, GABA-B; Thalamus | 2001 |
Excitatory synaptic input to granule cells increases with time after kainate treatment.
Topics: Action Potentials; Animals; Bicuculline; Coloring Agents; Convulsants; Cytoplasmic Granules; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Photic Stimulation; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2001 |
Enhanced but fragile inhibition in the dentate gyrus in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis.
Topics: Animals; Bicuculline; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Agonists; GABA Antagonists; Kainic Acid; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Nerve Degeneration; Neural Inhibition; Neuronal Plasticity; Neurons; Perforant Pathway; Rats; Rats, Long-Evans; Synaptic Transmission | 2001 |
Discharge threshold is enhanced for several seconds after a single interictal spike in a model of focal epileptogenesis.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Epilepsy; GABA Antagonists; Guinea Pigs; Neurons; Olfactory Pathways; Penicillins; Reaction Time | 2001 |
Long-term hyperexcitability in the hippocampus after experimental head trauma.
Topics: Animals; Bicuculline; Convulsants; Disease Models, Animal; Electric Stimulation; Electrophysiology; Epilepsy, Post-Traumatic; Evoked Potentials; Head Injuries, Closed; Hippocampus; Humans; Mossy Fibers, Hippocampal; Rats; Time Factors | 2001 |
Nociceptin, OP4 receptor ligand in different models of experimental epilepsy.
Topics: Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Epilepsy; Female; Mice; N-Methylaspartate; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pentylenetetrazole; Receptors, Opioid | 2002 |
Manipulation of the somatosensory cortex modulates stimulus-induced repetitive ear movements in a seizure-sensitive strain of gerbil.
Topics: Animals; Bicuculline; Disease Models, Animal; Ear; Evoked Potentials, Somatosensory; Female; GABA Antagonists; Gerbillinae; Male; Seizures; Somatosensory Cortex | 2001 |
Inhibitory role of the zona incerta in the pilocarpine model of epilepsy.
Topics: Animals; Bicuculline; Brain Mapping; Disease Models, Animal; Electroencephalography; Epilepsy; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Male; Muscimol; Pilocarpine; Rats; Rats, Wistar; Subthalamus | 2002 |
Neuronal activity in the monkey motor thalamus during bicuculline-induced dystonia.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; Dystonia; Electric Stimulation; Female; GABA Antagonists; GABA-A Receptor Antagonists; Macaca fascicularis; Motor Cortex; Neural Inhibition; Neural Pathways; Neurons; Receptors, GABA-A; Ventral Thalamic Nuclei | 2002 |
Kindling of the mesolimbic dopamine system: animal model of psychosis.
Topics: Animals; Behavior; Bicuculline; Cats; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Electroencephalography; Female; Humans; Hydroxydopamines; Limbic System; Male; Psychotic Disorders | 1978 |
Four models for studying cerebral lesions secondary to epileptic seizures.
Topics: Animals; Astrocytes; Bicuculline; Blood Gas Analysis; Blood Glucose; Blood Pressure; Body Temperature; Cerebellum; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; Gallamine Triethiodide; Gliosis; Glycine; Hippocampus; Ischemia; Papio; Pentylenetetrazole; Purkinje Cells | 1975 |
Seizure circuit analysis with voltage sensitive dye.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Brain; Brain Mapping; Disease Models, Animal; Fluorescent Dyes; Kainic Acid; Limbic System; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
A rodent model of focally evoked self-sustaining status epilepticus.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1992 |
Secondary generalization in non-kindled rats following acute administration of GABA-complex and adenosine antagonists.
Topics: Adenosine; Aminophylline; Amygdala; Animals; Bicuculline; Carbolines; Cerebral Cortex; Disease Models, Animal; Electrodes, Implanted; Epilepsies, Partial; GABA Antagonists; Harmine; Kindling, Neurologic; Male; Picrotoxin; Rats | 1990 |
Effects of amperozide in two animal models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Brain Chemistry; Conflict, Psychological; Disease Models, Animal; Drinking Behavior; Electroshock; Flumazenil; Male; Piperazines; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Benzodiazepine/gamma-aminobutyric acid receptor deficit in the midbrain of the seizure-susceptible gerbil.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Flunitrazepam; Gerbillinae; Mesencephalon; Muscimol; Pentobarbital; Receptors, GABA-A; Seizures | 1985 |
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep | 1987 |
Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Female; Hypnotics and Sedatives; Kindling, Neurologic; Male; Mice; Motor Skills; Papio; Pentylenetetrazole; Photic Stimulation; Pyridazines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1986 |
Anticonvulsant actions of enflurane on epilepsy models in cats.
Topics: Amygdala; Animals; Anticonvulsants; Bicuculline; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Enflurane; Epilepsy; Female; Kindling, Neurologic; Male; Penicillin G; Seizures | 1985 |