bicuculline has been researched along with Anxiety in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.56) | 18.7374 |
| 1990's | 10 (16.39) | 18.2507 |
| 2000's | 15 (24.59) | 29.6817 |
| 2010's | 30 (49.18) | 24.3611 |
| 2020's | 2 (3.28) | 2.80 |
| Authors | Studies |
|---|---|
| Goodpaster, C; Leuner, B; Maurer, S; Sabihi, S | 1 |
| Esumi, S; Izushi, Y; Kitamura, Y; Matsumoto, D; Noda, Y; Sendo, T; Ushio, S; Wada, Y | 1 |
| Almada, RC; Coimbra, NC; Genewsky, AJ; Heinz, DE; Kaplick, PM; Wotjak, CT | 1 |
| Chang, FC; Cheng, CH; Hsiao, YT; Yi, PL | 1 |
| Bi, LL; Chen, SP; Chen, YH; Gao, TM; Geng, F; Li, SJ; Lin, S; Luo, ZY; Wang, J; Yuan, CH | 1 |
| Adamik, A; Telegdy, G | 2 |
| Aguiar, JC; Guimarães, FS; Lisboa, SF; Magesto, AC; Resstel, LB | 1 |
| Chavan, JG; Salunke, BP; Umathe, SN | 1 |
| Jászberényi, M; Telegdy, G | 1 |
| Hesami-Tackallou, S; Nasehi, M; Naseri, MH; Torabi-Nami, M; Zarrindast, MR | 1 |
| Jászberényi, M; Palotai, M; Telegdy, G | 1 |
| Cai, J; Fang, D; Jiang, H; Jin, ZR; Kang, XJ; Kong, LY; Wan, Y; Xing, GG | 1 |
| Bahia, AP; de Figueiredo Müller-Ribeiro, FC; Fontes, MA; Frézard, F; Moreira, FA; Patel, KP; Santos, RA; Vaz, GC; Xavier, CH | 1 |
| Pavlova, IV; Rysakova, MP | 1 |
| Bakhtiari, A; Homberg, JR; Salari, AA | 1 |
| Farahizadeh, M; Nasehi, M; Zarrabian, S; Zarrindast, MR | 1 |
| Bi, LL; Gao, TM; Geng, F; Huang, CQ; Kong, Y; Li, XW; Liang, ZP; Liu, JH; Wu, JL; Yang, JM; Zhang, J; Zou, WJ | 1 |
| Palotai, M; Telegdy, G | 1 |
| Ohinata, K; Sonada, S; Yoshikawa, A; Yoshikawa, M; Zhao, H | 1 |
| DesJardin, JT; Elorette, C; Forcelli, PA; Holmes, AL; Malkova, L; Wellman, LL; West, EA | 1 |
| Amani, M; Salari, AA | 1 |
| Breese, GR; Knapp, DJ; Overstreet, DH; Wills, TA | 1 |
| Oryan, S; Parivar, K; Solati, J; Zarrindast, MR | 1 |
| Cranney, J; Zhang, S | 1 |
| Frye, CA; Paris, JJ | 2 |
| Hasanein, P; Keshavarz, S; Moghaddam, AH; Rezvani, ME; Roohbakhsh, A | 1 |
| Belzung, C; Chapouthier, G; Clément, Y; Le Guisquet, AM; Venault, P | 1 |
| Lonstein, JS; Miller, SM; Peabody, MF; Piasecki, CC | 1 |
| Crespo-Ramírez, M; Flores-Gracia, C; Fuxe, K; Miledi, R; Nuche-Bricaire, A; Pérez de la Mora, M | 1 |
| Brandão, ML; Cabral, A; Nobre, MJ | 1 |
| Ahmadi, R; Ashabi, G; Oryan, S; Valizadegan, F | 1 |
| Borges, AC; Faria, MS; Ganzer, L; Januário, AC; Kochenborger, L; Lopes, AP; Marino-Neto, J; Paschoalini, MA | 1 |
| Schally, AV; Telegdy, G | 1 |
| Chen, HF; Su, HM | 1 |
| Bortoli, VC; Camplesi, M; Nogueira, RL; Soares, Vde P; Zangrossi, H | 1 |
| Babri, S; Doosti, MH; Fatehi-Gharehlar, L; Kosari-Nasab, M; Pakzad, S | 1 |
| Ferguson, C; Grobin, AC; Homanics, GE; Kralic, JE; Morrow, AL; O'Buckley, TK; Renzi, K; Wheeler, M | 1 |
| Chopde, CT; Khisti, RT; Kokare, DM; Rao, TL; Sarkar, S; Subhedar, N | 1 |
| Chopde, CT; Hirani, K; Jain, NS | 1 |
| Djahanguiri, B; Massoudi, R; Rezayat, M; Roohbakhsh, A; Zarrindast, MR | 1 |
| Beleboni, Rde O; Coutinho-Netto, J; Cunha, AO; dos Santos, WF; Gelfuso, EA; Liberato, JL; Mortari, MR | 1 |
| Cho, YW; Jang, CG; Jin, C; Jung, JW; Lee, JJ; Oh, TH; Ryu, JH; Yoon, BH | 1 |
| Chopde, CT; Hirani, K; Kokare, DM; Sharma, AN; Subhedar, NK; Ugale, RR | 1 |
| Hajizadeh Moghaddam, A; Heidary-Davishani, A; Roohbakhsh, A; Rostami, P; Zarrindast, MR | 1 |
| Colwell, DD; Kavaliers, M | 1 |
| Katner, JS; Shekhar, A | 1 |
| Bowsher, RR; Shekhar, A; Sims, LS | 1 |
| Shekhar, A | 1 |
| Sanders, SK; Shekhar, A | 1 |
| Morzorati, SL; Sanders, SK; Shekhar, A | 1 |
| Biró, E; Penke, B; Telegdy, G | 1 |
| Sajdyk, TJ; Shekhar, A | 1 |
| Fernández-Guasti, A; López-Rubalcava, C | 1 |
| Gause, L; Kampov-Polevoy, AB; Matthews, DB; Morrow, AL; Overstreet, DH | 1 |
| DiMicco, JA; Hingtgen, JN; Shekhar, A | 1 |
| Engel, JA; Söderpalm, B | 1 |
| Bhadra, S; Idemudia, SO; Lal, H | 1 |
| Gray, JA; Henney, S; Lawson, P; Mellanby, J; Quintero, S | 1 |
| Buckland, C; Gray, JA; Mellanby, J | 1 |
61 other study(ies) available for bicuculline and Anxiety
| Article | Year |
|---|---|
GABA in the medial prefrontal cortex regulates anxiety-like behavior during the postpartum period.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Male; Maternal Deprivation; Muscimol; Prefrontal Cortex; Puerperal Disorders; Rats, Sprague-Dawley | 2021 |
Bumetanide prevents diazepam-modified anxiety-like behavior in lipopolysaccharide-treated mice.
Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Anxiety; Behavior, Animal; Bicuculline; Bumetanide; Diazepam; Emotions; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Inflammation; Lipopolysaccharides; Male; Mice, Inbred ICR; Minocycline; Motor Activity; Sodium Potassium Chloride Symporter Inhibitors | 2021 |
Stimulation of the Nigrotectal Pathway at the Level of the Superior Colliculus Reduces Threat Recognition and Causes a Shift From Avoidance to Approach Behavior.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Choice Behavior; Fear; Mice, Inbred C57BL; Neural Pathways; Neurons; Superior Colliculi | 2018 |
Disruption of footshock-induced theta rhythms by stimulating median raphe nucleus reduces anxiety in rats.
Topics: Animals; Anxiety; Bicuculline; Electric Stimulation; Electroshock; GABA-A Receptor Antagonists; GABAergic Neurons; Male; Neurons; Raphe Nuclei; Rats; Rats, Wistar; Theta Rhythm | 2013 |
Enhanced excitability in the infralimbic cortex produces anxiety-like behaviors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Anxiety; Bicuculline; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Prefrontal Cortex | 2013 |
Involvement of transmitters in the anxiolytic action of urocortin 3 in mice.
Topics: Analysis of Variance; Animals; Anxiety; Atropine; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Maze Learning; Methysergide; Mice; Naloxone; Neurotransmitter Agents; Propranolol; Time Factors; Urocortins | 2013 |
Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats.
Topics: Animals; Anxiety; Apomorphine; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA-A Receptor Antagonists; Male; Maze Learning; Nitric Oxide Synthase; Oxadiazoles; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2013 |
Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice.
Topics: Animals; Anxiety; Bicuculline; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Magnetic Fields; Male; Maze Learning; Mice; Muscimol; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Social Behavior; Time Factors | 2014 |
Transmitter mediation of the anxiolytic action of apelin-13 in male mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA-A Receptor Antagonists; Haloperidol; Intercellular Signaling Peptides and Proteins; Male; Maze Learning; Methysergide; Mice; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Receptors, Neurotransmitter; Serotonin Antagonists | 2014 |
Involvement of the CA1 GABAA receptors in MK-801-induced anxiolytic-like effects: an isobologram analysis.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; CA1 Region, Hippocampal; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; GABA Agents; Male; Maze Learning; Microinjections; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A | 2014 |
Orexin A-induced anxiety-like behavior is mediated through GABA-ergic, α- and β-adrenergic neurotransmissions in mice.
Topics: Animals; Anxiety; Atropine; Behavior, Animal; Bicuculline; gamma-Aminobutyric Acid; Haloperidol; Intracellular Signaling Peptides and Proteins; Mice; Neuropeptides; Neurotransmitter Agents; Orexins; Phenoxybenzamine; Propranolol | 2014 |
Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats.
Topics: Action Potentials; Animals; Anxiety; Apoptosis; Behavior, Animal; Bicuculline; Blotting, Western; Caspase 3; Cell Membrane; Central Amygdaloid Nucleus; GABAergic Neurons; Hyperalgesia; In Situ Nick-End Labeling; Ligation; Male; Muscimol; Neural Inhibition; Neuralgia; Rats, Sprague-Dawley; Spinal Nerves | 2014 |
Cardiovascular and behavioral effects produced by administration of liposome-entrapped GABA into the rat central nervous system.
Topics: Animals; Anxiety; Arterial Pressure; Bicuculline; Cardiovascular Agents; Catheters, Indwelling; Central Nervous System Agents; Exploratory Behavior; GABA Agents; gamma-Aminobutyric Acid; Heart Rate; Infusions, Intraventricular; Kidney; Liposomes; Male; Microinjections; Rats, Wistar; Stress, Physiological; Sympathetic Nervous System; Tachycardia | 2015 |
Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats.
Topics: Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Arginine; Atropine; Bicuculline; Dopamine Antagonists; Exploratory Behavior; Haloperidol; Male; Maze Learning; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nitroso Compounds; Peptide Fragments; Phenoxybenzamine; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar; Receptors, GABA; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Serotonin 5-HT2 Receptor Antagonists | 2015 |
[Behavior of high- and low-anxiety rats after modulation of GABAergic transmission in basolateral amygdala].
Topics: Aggression; Animals; Anxiety; Basolateral Nuclear Complex; Bicuculline; Functional Laterality; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Locomotion; Male; Maze Learning; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Severity of Illness Index; Synaptic Transmission | 2014 |
Activation of GABA-A receptors during postnatal brain development increases anxiety- and depression-related behaviors in a time- and dose-dependent manner in adult mice.
Topics: Animals; Animals, Newborn; Anxiety; Bicuculline; Brain; Corticosterone; Depression; Dose-Response Relationship, Drug; Male; Mice; Muscimol; Receptors, GABA-A; Stress, Psychological; Time Factors | 2015 |
The role of CA3 GABAA receptors on anxiolytic-like behaviors and avoidance memory deficit induced by NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Avoidance Learning; Bicuculline; CA3 Region, Hippocampal; Male; Maze Learning; Memory; Memory Disorders; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2016 |
Neuregulin 1-ErbB4 signaling in the bed nucleus of the stria terminalis regulates anxiety-like behavior.
Topics: Animals; Anxiety; Bicuculline; Central Nervous System Agents; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Mice, Inbred C57BL; Models, Animal; Neuregulin-1; Presynaptic Terminals; Pyrimidines; Receptor, ErbB-4; Receptors, GABA-A; Septal Nuclei; Tissue Culture Techniques | 2016 |
Anxiolytic effect of the GPR103 receptor agonist peptide P550 (homolog of neuropeptide 26RFa) in mice. Involvement of neurotransmitters.
Topics: Animals; Anxiety; Atropine; Bicuculline; Cyproheptadine; Haloperidol; Methysergide; Mice; Neuropeptides; Neurotransmitter Agents; Phenoxybenzamine; Propranolol; Receptors, G-Protein-Coupled; Receptors, GABA-A | 2016 |
Rubimetide, humanin, and MMK1 exert anxiolytic-like activities via the formyl peptide receptor 2 in mice followed by the successive activation of DP1, A2A, and GABAA receptors.
Topics: Adenosine A2 Receptor Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; GABA-A Receptor Antagonists; Humans; Intracellular Signaling Peptides and Proteins; Mice; Peptide Fragments; Peptides; Receptor, Adenosine A2A; Receptors, Formyl Peptide; Receptors, GABA-A; Ribulose-Bisphosphate Carboxylase; Spinacia oleracea; Transcription Factor DP1 | 2016 |
Amygdala selectively modulates defensive responses evoked from the superior colliculus in non-human primates.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Macaca mulatta; Macaca nemestrina; Male; Muscimol; Superior Colliculi | 2016 |
Neonatal blockade of GABA-A receptors alters behavioral and physiological phenotypes in adult mice.
Topics: Adaptation, Ocular; Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Bicuculline; Body Weight; Corticosterone; Depression; Disease Models, Animal; Eating; Female; GABA-A Receptor Antagonists; Hindlimb Suspension; Male; Maze Learning; Mice; Receptors, GABA-A; Sex Factors; Swimming; Testosterone | 2017 |
Differential dietary ethanol intake and blood ethanol levels in adolescent and adult rats: effects on anxiety-like behavior and seizure thresholds.
Topics: Aging; Alcohol Drinking; Alcohol Withdrawal Seizures; Animals; Anxiety; Behavior, Animal; Bicuculline; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Reflex; Ethanol; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Seizures; Social Behavior | 2008 |
Effect of intra-amygdala injection of nicotine and GABA receptor agents on anxiety-like behaviour in rats.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Male; Maze Learning; Mecamylamine; Motor Activity; Muscimol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Nicotinic | 2008 |
The role of GABA and anxiety in the reconsolidation of conditioned fear.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Bicuculline; Conditioning, Psychological; Disease Models, Animal; Electroshock; Fear; Freezing Reaction, Cataleptic; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Maze Learning; Memory; Midazolam; Rats; Rats, Sprague-Dawley; Stress, Psychological; Time Factors | 2008 |
Infusions of bicuculline to the ventral tegmental area attenuates sexual, exploratory, and anti-anxiety behavior of proestrous rats.
Topics: Animals; Anxiety; Bicuculline; Consummatory Behavior; Desoxycorticosterone; Estrous Cycle; Exploratory Behavior; Female; GABA Antagonists; Hormones; Interpersonal Relations; Microinjections; Motor Activity; Neurosecretory Systems; Posture; Rats; Rats, Long-Evans; Receptors, GABA-A; Sexual Behavior, Animal; Stereotaxic Techniques; Ventral Tegmental Area | 2009 |
Role of endocannabinoid system in the ventral hippocampus of rats in the modulation of anxiety-like behaviours.
Topics: Amidohydrolases; Animals; Anxiety; Baclofen; Behavior, Animal; Benzamides; Bicuculline; Cannabinoid Receptor Modulators; Carbamates; Dose-Response Relationship, Drug; Endocannabinoids; GABA Antagonists; Hippocampus; Male; Maze Learning; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2009 |
Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Chlordiazepoxide; Female; Indoles; Light; Male; Maze Learning; Mice; Mice, Inbred C57BL; Phosphorylation | 2009 |
GABA(A) receptor antagonism in the ventrocaudal periaqueductal gray increases anxiety in the anxiety-resistant postpartum rat.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Blood-Air Barrier; Catheterization; Depression, Postpartum; Dose-Response Relationship, Drug; Exploratory Behavior; Female; GABA-A Receptor Antagonists; Infusions, Parenteral; Periaqueductal Gray; Postpartum Period; Rats; Rats, Long-Evans | 2010 |
GABA(A) ρ receptor mechanisms in the rat amygdala and its role in the modulation of fear and anxiety.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Corticosterone; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; GABA-A Receptor Antagonists; Male; Microdialysis; Motor Activity; Phosphinic Acids; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Seizures | 2010 |
Effects of neurosteroid actions at N-methyl-D-aspartate and GABA A receptors in the midbrain ventral tegmental area for anxiety-like and mating behavior of female rats.
Topics: Adrenalectomy; Animals; Anxiety; Bicuculline; Dizocilpine Maleate; Female; GABA-A Receptor Antagonists; Indoleacetic Acids; Male; Maze Learning; Microinjections; Neurotransmitter Agents; Rats; Rats, Long-Evans; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sexual Behavior, Animal; Social Behavior; Ventral Tegmental Area | 2011 |
GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Clonixin; Conditioning, Classical; Diazepam; Disease Models, Animal; Electroencephalography; Evoked Potentials, Auditory; Fear; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Male; Maze Learning; Microinjections; Muscimol; Neurons; Prostaglandin Antagonists; Rats; Rats, Wistar; Sensory Gating; Statistics as Topic | 2010 |
The effects of hippocampal opioidergic and septal GABAergic system interactions on anxiety-like behavior in rats.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; CA1 Region, Hippocampal; GABA Agonists; GABA Antagonists; Hippocampus; Male; Microinjections; Morphine; Muscimol; Narcotics; Rats; Rats, Wistar; Receptors, GABA; Receptors, Opioid, mu; Septum of Brain | 2011 |
Effects of GABA ligands injected into the nucleus accumbens shell on fear/anxiety-like and feeding behaviours in food-deprived rats.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Eating; Fear; Feeding Behavior; Food Deprivation; GABA Agents; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Microinjections; Muscimol; Nucleus Accumbens; Rats; Rats, Wistar; Stereotaxic Techniques | 2012 |
Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Bicuculline; Cyproheptadine; Disease Models, Animal; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Maze Learning; Methysergide; Mice; Neurotransmitter Agents; Phenoxybenzamine; Prazosin; Sermorelin; Swimming | 2012 |
Exposure to a maternal n-3 fatty acid-deficient diet during brain development provokes excessive hypothalamic-pituitary-adrenal axis responses to stress and behavioral indices of depression and anxiety in male rat offspring later in life.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Brain; Corticosterone; Depression; Docosahexaenoic Acids; Fatty Acids, Omega-3; Female; Fish Oils; GABA Antagonists; Glutamate Decarboxylase; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Plant Oils; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sunflower Oil; Weaning | 2013 |
Dorsal periaqueductal gray stimulation facilitates anxiety-, but not panic-related, defensive responses in rats tested in the elevated T-maze.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Electrodes, Implanted; Escape Reaction; Male; Maze Learning; Panic Disorder; Periaqueductal Gray; Rats; Rats, Wistar | 2012 |
Involvement of GABAergic system in regulation of the anxiolytic- and antidepressant-like effects of Scrophularia striata extract in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Bicuculline; Brain; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Maze Learning; Muscimol; Plant Extracts; Rats; Rats, Wistar; Receptors, GABA-A; Scrophularia; Swimming | 2013 |
Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.
Topics: Anesthetics; Animals; Anxiety; Behavior, Animal; Bicuculline; Brain; Central Nervous System Depressants; Chlorides; Desoxycorticosterone; Drug Tolerance; Ethanol; Exploratory Behavior; Female; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Knockout; Muscimol; Postural Balance; Pregnanolone; Receptors, GABA-A; Steroids | 2003 |
GABAergic agents prevent alpha-melanocyte stimulating hormone induced anxiety and anorexia in rats.
Topics: alpha-MSH; Animals; Anorexia; Anxiety; Bicuculline; Darkness; Diazepam; Eating; GABA Agents; GABA Antagonists; GABA Modulators; Injections, Intraventricular; Light; Male; Rats; Rats, Sprague-Dawley | 2003 |
Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats.
Topics: Adrenalectomy; Analysis of Variance; Anesthetics; Animals; Anxiety; Bicuculline; Caffeine; Central Nervous System Stimulants; Corticotropin-Releasing Hormone; Diazepam; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Hormone Antagonists; Injections, Intraventricular; Male; Maze Learning; Muscimol; Peptide Fragments; Pregnanolone; Progestins; Rats; Rats, Sprague-Dawley; Reaction Time | 2005 |
Cholecystokinin and GABA interaction in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety.
Topics: Animals; Anxiety; Bicuculline; Cholecystokinin; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microinjections; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stereotaxic Techniques | 2005 |
Anticonvulsant and anxiolytic activity of FrPbAII, a novel GABA uptake inhibitor isolated from the venom of the social spider Parawixia bistriata (Araneidae: Araneae).
Topics: Analysis of Variance; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Bicuculline; Choice Behavior; Diazepam; Disease Models, Animal; Drug Interactions; Hippocampus; Male; Maze Learning; Neuroprotective Agents; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Spider Venoms; Spiders; Substantia Nigra; Urea | 2006 |
Anxiolytic-like effects of sinapic acid in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Cerebral Cortex; Chloride Channels; Coumaric Acids; Diazepam; Electrophysiology; Flumazenil; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Relaxation; Muscle, Smooth; Neurons; Neurotransmitter Agents; Piperazines; Postural Balance; Pyridines; Serotonin Antagonists | 2007 |
Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.
Topics: Adrenalectomy; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Male; Maze Learning; Muscimol; Oxazines; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time | 2007 |
GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; gamma-Aminobutyric Acid; Histamine; Histamine Agents; Male; Maze Learning; Microinjections; Muscimol; Pyrilamine; Rats; Rats, Wistar | 2008 |
Decreased predator avoidance in parasitized mice: neuromodulatory correlates.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A | 1995 |
Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Parasympatholytics; Picrotoxin; Rats; Rats, Sprague-Dawley; Social Behavior | 1995 |
GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test. II. Physiological measures.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Avoidance Learning; Bicuculline; Blood Pressure; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1993 |
GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test. I. Behavioral measures.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Blood Pressure; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Respiration | 1993 |
Regulation of anxiety by GABAA receptors in the rat amygdala.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Interpersonal Relations; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Priming of experimental anxiety by repeated subthreshold GABA blockade in the rat amygdala.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; GABA Antagonists; Heart Rate; Interpersonal Relations; Long-Term Potentiation; Male; Rats; Rats, Wistar; Time Factors | 1995 |
Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA Antagonists; Haloperidol; Injections, Intraventricular; Male; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists; Sincalide | 1997 |
Excitatory amino acid receptor antagonists block the cardiovascular and anxiety responses elicited by gamma-aminobutyric acidA receptor blockade in the basolateral amygdala of rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Hemodynamics; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Modification of the anxiolytic action of 5-HT1A compounds by GABA-benzodiazepine agents in rats.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Buspirone; Diazepam; Drug Interactions; Flumazenil; GABA Agonists; Male; Psychomotor Performance; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 1998 |
P rats develop physical dependence on alcohol via voluntary drinking: changes in seizure thresholds, anxiety, and patterns of alcohol drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Anxiety; Bicuculline; Convulsants; Disease Models, Animal; Rats; Seizures; Substance Withdrawal Syndrome | 2000 |
GABA receptors in the posterior hypothalamus regulate experimental anxiety in rats.
Topics: Animals; Anxiety; Bicuculline; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Does the PCPA induced anticonflict effect involve activation of the GABAA/benzodiazepine chloride ionophore receptor complex?
Topics: Animals; Anxiety; Bicuculline; Brain; Dose-Response Relationship, Drug; Fenclonine; Flumazenil; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1989 |
The pentylenetetrazol-like interoceptive stimulus produced by ethanol withdrawal is potentiated by bicuculline and picrotoxinin.
Topics: Animals; Anxiety; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; GABA Antagonists; Male; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Sesterterpenes; Substance Withdrawal Syndrome | 1989 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing.
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Bicuculline; Carbolines; Chlordiazepoxide; Drug Interactions; Humans; Male; Muscimol; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1985 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: extinction and successive discrimination.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Chlordiazepoxide; Discrimination Learning; Discrimination, Psychological; Drug Interactions; Extinction, Psychological; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors | 1986 |