bicuculline has been researched along with Absence Seizure Disorder in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Forcelli, PA; Wicker, E | 1 |
| Blumenfeld, H; Erdogan, E; Herman, P; Hyder, F; Nersesyan, H | 1 |
| Aker, RG; Cakmak, YO; Cavdar, S; Onat, FY; Ozkaynakçi, AE; Ozyurt, HB; Saka, E; Sehirli, U; Yananli, HR | 1 |
| Aker, RG; Aypak, C; Goren, MZ; Onat, FY; Terzioğlu, B; Yananli, HR | 1 |
| Wallenstein, GV | 1 |
| Bal, T; McCormick, DA; von Krosigk, M | 1 |
| Matejovská, I; Velísek, L; Velísková, J | 1 |
| Aker, R; Ateş, N; Karson, AB; Onat, F | 1 |
| Boehrer, A; Marescaux, C; Reibel, S; Simler, S; Vergnes, M | 1 |
| Pape, HC; Staak, R | 1 |
| Pape, HC; Seidenbecher, T | 1 |
| Aker, RG; Onat, FY | 1 |
| Aker, RG; Dervent, A; Ozkara, C; Yilmaz Onat, F | 1 |
| Englander, RN; Hanna, GR; Johnson, RN | 1 |
| King, GA | 1 |
| Brickley, JJ; Englander, RN; Hanna, GR; Johnson, RN | 1 |
| Coulter, DA; Huguenard, JR; Prince, DA | 1 |
1 trial(s) available for bicuculline and Absence Seizure Disorder
| Article | Year |
|---|---|
Ethosuximide and bicuculline inhibition in petit mal epilepsy.
Topics: Animals; Bicuculline; Cats; Clinical Trials as Topic; Epilepsy, Absence; Ethosuximide; Evoked Potentials; GABA Antagonists; Humans; Isoquinolines; Motor Cortex; Thalamus | 1977 |
16 other study(ies) available for bicuculline and Absence Seizure Disorder
| Article | Year |
|---|---|
Optogenetic activation of the reticular nucleus of the thalamus attenuates limbic seizures via inhibition of the midline thalamus.
Topics: Bicuculline; Epilepsy, Absence; Humans; Optogenetics; Seizures; Thalamus | 2021 |
Relative changes in cerebral blood flow and neuronal activity in local microdomains during generalized seizures.
Topics: Animals; Bicuculline; Brain; Cerebrovascular Circulation; Convulsants; Disease Models, Animal; Epilepsy, Absence; Female; Laser-Doppler Flowmetry; Microelectrodes; Neurons; Rats; Rats, Inbred Strains; Vibrissae | 2004 |
GABA(A) receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: functional implications.
Topics: Action Potentials; Afferent Pathways; Animals; Basal Ganglia; Bicuculline; Cerebral Cortex; Disease Models, Animal; Epilepsy, Absence; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Intralaminar Thalamic Nuclei; Neural Inhibition; Rats; Rats, Wistar; Receptors, GABA-A; Substantia Nigra; Synaptic Transmission; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2006 |
Extracellular hypothalamic gamma-aminobutyric acid (GABA) and L-glutamic acid concentrations in response to bicuculline in a genetic absence epilepsy rat model.
Topics: Animals; Bicuculline; Blood Pressure; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hypothalamus; Male; Rats; Rats, Wistar | 2008 |
The role of thalamic IGABAB in generating spike-wave discharges during petit mal seizures.
Topics: Animals; Bicuculline; Cats; Computer Simulation; Electroencephalography; Epilepsy, Absence; gamma-Aminobutyric Acid; Models, Neurological; Potassium Channels; Rats; Receptors, GABA; Thalamic Nuclei; Thalamus | 1994 |
Cellular mechanisms of a synchronized oscillation in the thalamus.
Topics: Animals; Baclofen; Bicuculline; Calcium; Epilepsy, Absence; Ferrets; Geniculate Bodies; In Vitro Techniques; Membrane Potentials; Neurons; Potassium; Receptors, Amino Acid; Receptors, GABA-A; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1993 |
Bicuculline-induced rhythmic EEG episodes: gender differences and the effects of ethosuximide and baclofen treatment.
Topics: Animals; Baclofen; Bicuculline; Epilepsy; Epilepsy, Absence; Estradiol; Ethosuximide; Female; Incidence; Male; Ovariectomy; Rats; Rats, Wistar; Sex Factors | 1998 |
Cardiovascular effects of intracerebroventricular bicuculline in rats with absence seizures.
Topics: Amygdala; Animals; Bicuculline; Blood Pressure; Cardiovascular System; Epilepsy, Absence; Female; GABA Antagonists; Heart Rate; Injections, Intraventricular; Male; Rats; Rats, Mutant Strains; Rats, Wistar; Reference Values | 1999 |
Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABA(A) receptor in rats with genetic absence epilepsy.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Carbolines; Convulsants; Electroencephalography; Epilepsy, Absence; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Kainic Acid; Limbic System; Male; Parietal Lobe; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Strychnine | 2000 |
Contribution of GABA(A) and GABA(B) receptors to thalamic neuronal activity during spontaneous absence seizures in rats.
Topics: Action Potentials; Animals; Bicuculline; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Linear Models; Male; Neurons; Phosphinic Acids; Propanolamines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, GABA-B; Thalamus | 2001 |
Contribution of intralaminar thalamic nuclei to spike-and-wave-discharges during spontaneous seizures in a genetic rat model of absence epilepsy.
Topics: Action Potentials; Animals; Bicuculline; Electroencephalography; Electrophysiology; Epilepsy, Absence; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Intralaminar Thalamic Nuclei; Male; Neurons; Rats; Rats, Mutant Strains; Reaction Time; Recruitment, Neurophysiological; Seizures | 2001 |
Cardiovascular regulation through hypothalamic GABA(A) receptors in a genetic absence epilepsy model in rat.
Topics: Animals; Bicuculline; Blood Pressure; Body Mass Index; Brain; Cardiovascular System; Convulsants; Electroencephalography; Epilepsy, Absence; GABA Antagonists; Heart Rate; Hypothalamus; Rats; Rats, Mutant Strains; Rats, Wistar; Receptors, GABA-A; Reference Values | 2002 |
Enhancement of spike and wave discharges by microinjection of bicuculline into the reticular nucleus of rats with absence epilepsy.
Topics: Action Potentials; Animals; Bicuculline; Blood Pressure; Epilepsy, Absence; Female; GABA Antagonists; GABA-A Receptor Antagonists; Heart Rate; Male; Microinjections; Rats; Rats, Mutant Strains; Rats, Wistar; Receptors, GABA-A; Thalamic Nuclei | 2002 |
Effects of systemically applied GABA agonists and antagonists on wave-spike ECoG activity in rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Male; Muscimol; Photic Stimulation; Picrotoxin; Rats; Strychnine | 1979 |
Effects of antiepileptic drugs on thalamocortical excitability.
Topics: Animals; Bicuculline; Cats; Computers; Diazepam; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Motor Cortex; Phenytoin; Thalamus; Time Factors | 1977 |
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Neurons; Pentylenetetrazole; Picrotoxin; Rats; Succinimides; Thalamus | 1990 |