bicalutamide and Hormone-Dependent Neoplasms

bicalutamide has been researched along with Hormone-Dependent Neoplasms in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (14.29)18.2507
2000's37 (52.86)29.6817
2010's21 (30.00)24.3611
2020's2 (2.86)2.80

Authors

AuthorsStudies
Aebersold, DM; Albrecht, C; Böhmer, D; Flentje, M; Ganswindt, U; Ghadjar, P; Höcht, S; Hölscher, T; Müller, AC; Niehoff, P; Pinkawa, M; Sedlmayer, F; Wiegel, T; Zips, D1
Asioli, S; Fabbri, VP; Palandri, G1
Argellati, F; Boccardo, F; Mangerini, R; Nuzzo, PV; Ricci, F; Rubagotti, A1
Campbell, DC; Johnston, R; McDade, SS; Nugent, S; Panov, KI; Ray, S; Waugh, D1
Anda, T; Honda, M; Ishihara, T; Kamei, T1
Bossi, P; Civelli, E; Cortelazzi, B; Imbimbo, M; Licitra, L; Locati, LD; Perrone, F; Pilotti, S; Potepan, P; Quattrone, P; Rinaldi, G1
Gooderham, NJ; Koufaris, C; Powell, C; Segal, CV1
Chesa, N; Déniz, F; Domínguez, C; Lara, PC; Lloret, M; Naranjo, A; Ojeda, S1
Burich, RA; Holland, WS; Mack, PC; Tepper, C; Vinall, RL; White, RW1
Balk, SP; Kaur, R; Lu, ML; Yuan, X1
Bagalà, C; Barone, C; Bianchetti, S; Cassano, A; Fabiano, A; Landriscina, M; Piscazzi, A; Quirino, M; Schinzari, G; Sica, G1
Chun, JY; Evans, CP; Feng, S; Gao, AC; Sun, M; Tang, Q1
Brown, M; Garabedian, MJ; Gerald, WL; Ha, S; Huang, SJ; Logan, SK; Mita, P; Nwachukwu, JC; Ruoff, R; Taneja, SS; Wang, Q1
Desiniotis, A; Eder, IE; Klocker, H; Schäfer, G1
Bonfili, P; Di Staso, M; Festuccia, C; Gravina, GL; Jannini, EA; Marampon, F; Pestell, RG; Tombolini, V; Vitturini, A1
Labrie, F1
Bryskin, I; Laflamme, P; Lin, H; Lu, JP; Monardo, L; Pinthus, JH; Qiao, S; Shayegan, B; Singh, G; Wilson, BC1
Brodie, AM; Goloubeva, O; Njar, VC; Sabnis, G; Schayowitz, A1
Foley, R; Hollywood, D; Keane, JP; Lynch, TH; Marignol, L1
Itoh, K; Kanayama, H; Kawabata, R; Oie, S; Oka, T; Takahashi, M1
Hara, T; Inoue, H; Ishizuya, Y; Okada, T; Takada, T; Ueda, T1
Caradec, J; Chimingqi, M; de la Taille, A; Giton, F; Kouyoumdjian, JC; Loric, S; Moutereau, S; Sirab, N; Terry, S; Vacherot, F1
Hu, CA; Kaini, RR; Sillerud, LO; Zhaorigetu, S1
Antony, L; Chen, S; D'Antonio, JM; Dalrymple, SP; Denmeade, SR; Isaacs, JT; Luo, J; Ndikuyeze, GH1
Erkkilä, T; Isola, J; Kaipia, A; Kujala, P; Lähdesmäki, H; Larjo, A; Lehmusvaara, S; Seppälä, J; Tammela, TLj; Tuominen, VJ; Urbanucci, A; Visakorpi, T; Waltering, K1
Corey, G; McDowell, C; McGivern, U; Mitchell, DM; O'Hare, J; O'Sullivan, JM1
Argellati, F; Boccardo, F; Mangerini, R; Pfeffer, U1
Agreda, F; Lopez, MA; Morote, J; Placer, J; Planas, J; Salvador, C; Trilla, E1
Chen, J; Lee, F; Scher, HI; She, Y; Sirotnak, FM1
Duncan, WE; Harding, P; Howard, RS; McLeod, DG; Preston, DM; Torréns, JI1
Bakin, RE; Bissonette, EA; Gioeli, D; Weber, MJ1
Araki, H; Hara, T; Kusaka, M; Nakamura, K; Yamaoka, M1
Chen, F; Iwamoto, Y; Langenstroer, P; See, W; Zhang, G1
De Marzo, AM; Denis, S; Ewing, CM; Ferdinandusse, S; Isaacs, WB; Luo, J; Wanders, RJ; Zha, S1
Hellerstedt, B1
Di Silverio, F; Sciarra, A1
Ferrari, AC; McCarron, JP; Mencher, SK; Wang, LG1
Cheskis, B; Mancini, MA; Marcelli, M; McPhaul, MJ; Nan, B; Sun, S; Unni, E1
Belfiore, A; Frasca, F; Marcelli, M; Mineo, R; Pandini, G; Roberts, CT; Vigneri, R1
Bedolla, RG; Ghosh, PM; Kreisberg, JI; Malik, SN; Mikhailova, M; Prihoda, TJ; Troyer, DA; Wang, Y1
Hara, T; Kouno, J; Kusaka, M; Nakamura, K; Yamaoka, M1
Wenlu, S; Zhigang, Z1
Chuu, CP; Dang, M; Fukuchi, J; Hiipakka, RA; Hsu, S; Kokontis, JM; Liao, S1
Brown, SC; Collins, GN; Manikandan, R; O'Reilly, P; Pearson, E; Srirangam, SJ1
Inoue, T; Kamoto, T; Kinoshita, H; Nakamura, E; Ogawa, O; Segawa, T; Shimizu, Y; Yoshida, T1
Conaway, M; Gioeli, D; Theodorescu, D; Weber, MJ; Wu, Z1
Arakaki, R; Kaneko, Y; Maekawa, S; Nishimura, K; Okada, Y; Terada, N1
Ellwood-Yen, K; Sawyers, C; Wongvipat, J1
Bryant, RJ; Cross, NA; Cunliffe, VT; Eaton, CL; Hamdy, FC1
Hara, S; Hyochi, N; Isaacs, JT; Ishioka, J; Kageyama, Y; Kihara, K; Singh, P; Urushibara, M1
Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Ricevuto, E; Ventura, L; Vicentini, C1
Bayley, A; Bristow, R; Catton, C; Chung, P; Gospodarowicz, M; Hill, R; Menard, C; Milosevic, M; Panzarella, T; Parker, C; Toi, A; Warde, P1
Bidaisee, LA; Bryskine, I; Gupta, RS; Lin, H; Lu, JP; Pinthus, JH; Singh, G1
Chung, LW; Huang, C; Huang, PT; Li, S; Liang, RX; Pang, B; Wang, J; Wang, R; Zhang, H; Zhau, HE; Zhou, JG1
Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Ventura, L; Vessella, RL; Vicentini, C1
Klotz, L1
Lorenzo, PI; Saatcioglu, F1
Bedolla, R; Ghosh, PM; Kreisberg, JI; Lu, XH; Mikhailova, M; Wang, Y1
Maucher, A; von Angerer, E1
Blackledge, G; Kolvenbag, G; Nash, A1
Feldman, D; Ly, LH; Peehl, DM; Zhao, XY1
Brett, C; Kelly, WK; Kolvenbag, G; Liebertz, C; Mazumdar, M; Scher, HI; Schwartz, L; Schwartz, M; Shapiro, L1
Akakura, K; Furuya, Y; Ito, H1
Balk, SP; Bubley, GJ; Ko, YJ; Rajeshkumar, B; Small, EJ; Taplin, ME; Upton, M1
Bartsch, G; Culig, Z; Eder, IE; Erdel, M; Hittmair, A; Hobisch, A; Hoffmann, J; Klocker, H; Parczyk, K; Schneider, MR; Utermann, G1
Richie, JP1
Kotake, T1
Furuya, Y; Fuse, H; Nagakawa, O; Nozaki, T1
Kennealey, GT; Vogelzang, NJ1

Reviews

8 review(s) available for bicalutamide and Hormone-Dependent Neoplasms

ArticleYear
Treatment strategies to prevent and reduce gynecomastia and/or breast pain caused by antiandrogen therapy for prostate cancer : Statement from the DEGRO working group prostate cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:7

    Topics: Adenocarcinoma; Anastrozole; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Dizziness; Dose Fractionation, Radiation; Drug Administration Schedule; Estrogen Receptor Modulators; Flushing; Gynecomastia; Humans; Male; Mastodynia; Meta-Analysis as Topic; Neoplasms, Hormone-Dependent; Nitriles; Off-Label Use; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Tamoxifen; Tosyl Compounds

2020
Hormonal therapy options for patients with a rising prostate-specific antigen level after primary treatment for prostate cancer.
    Urology, 2003, Dec-29, Volume: 62 Suppl 1

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Combined Modality Therapy; Diethylstilbestrol; Disease-Free Survival; Drug Administration Schedule; Enzyme Inhibitors; Finasteride; Gonadotropin-Releasing Hormone; Humans; Male; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Salvage Therapy; Tosyl Compounds; Treatment Outcome

2003
Maximal androgen blockade for advanced prostate cancer.
    Best practice & research. Clinical endocrinology & metabolism, 2008, Volume: 22, Issue:2

    Topics: Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease Progression; Dose-Response Relationship, Drug; Humans; Male; Meta-Analysis as Topic; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Survival Analysis; Tosyl Compounds; Withholding Treatment

2008
Bicalutamide: a new antiandrogen for use in combination with castration for patients with advanced prostate cancer.
    Anti-cancer drugs, 1996, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Flutamide; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Tosyl Compounds

1996
[Steroidal and nonsteroidal antiandrogens: chemical structures, mechanisms of action and clinical applications].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:8

    Topics: Androgen Antagonists; Anilides; Chlormadinone Acetate; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Hyperplasia; Prostatic Neoplasms; Tosyl Compounds

1998
Anti-androgens and other hormonal therapies for prostate cancer.
    Urology, 1999, Volume: 54, Issue:6A Suppl

    Topics: Androgen Antagonists; Androgens; Anilides; Biomarkers, Tumor; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

1999
[Bicalutamide].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58 Suppl

    Topics: Androgen Antagonists; Anilides; Antineoplastic Agents; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds

2000
Recent developments in endocrine treatment of prostate cancer.
    Cancer, 1992, Aug-15, Volume: 70, Issue:4 Suppl

    Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Buserelin; Clinical Trials as Topic; Gonadotropin-Releasing Hormone; Goserelin; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostatic Neoplasms; Tosyl Compounds

1992

Trials

4 trial(s) available for bicalutamide and Hormone-Dependent Neoplasms

ArticleYear
Chemical castration and anti-androgens induce differential gene expression in prostate cancer.
    The Journal of pathology, 2012, Volume: 227, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Bayes Theorem; Castration; Chemotherapy, Adjuvant; Chi-Square Distribution; Finland; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gonadotropin-Releasing Hormone; Goserelin; Humans; Injections, Subcutaneous; Male; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Prostatectomy; Prostatic Neoplasms; Tosyl Compounds; Treatment Outcome

2012
Effect of nonsteroidal antiandrogen monotherapy versus castration therapy on neuroendocrine differentiation in prostate carcinoma.
    Urology, 2004, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Aged; Androgens; Anilides; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Cell Differentiation; Chromogranin A; Chromogranins; Disease Progression; Gonadotropin-Releasing Hormone; Humans; Lymph Node Excision; Male; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neurosecretory Systems; Nitriles; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Tosyl Compounds; Triptorelin Pamoate

2004
Diethylstilboestrol versus bicalutamide in hormone refractory prostate carcinoma: a prospective randomized trial.
    Urologia internationalis, 2005, Volume: 75, Issue:3

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Carcinoma; Diethylstilbestrol; Drug Therapy, Combination; Follow-Up Studies; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds; Treatment Outcome

2005
Bicalutamide: a new antiandrogen for use in combination with castration for patients with advanced prostate cancer.
    Anti-cancer drugs, 1996, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Flutamide; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Tosyl Compounds

1996

Other Studies

59 other study(ies) available for bicalutamide and Hormone-Dependent Neoplasms

ArticleYear
An unusual case of "sterile" abscess within low-grade meningioma during anti androgenic therapy and LH-releasing hormone agonist treatment for prostate cancer.
    Clinical neurology and neurosurgery, 2020, Volume: 196

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Brain Abscess; Combined Modality Therapy; Craniotomy; Hearing Loss, Unilateral; Humans; Incidental Findings; Luteinizing Hormone; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Necrosis; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Neuroimaging; Nitriles; Prostatic Neoplasms; Tosyl Compounds

2020
Dihydrotestosterone and bicalutamide do not affect periostin expression in androgen-dependent LNCaP prostate cancer cell lines.
    Anticancer research, 2013, Volume: 33, Issue:3

    Topics: Androgens; Anilides; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; RNA, Messenger; Tosyl Compounds

2013
Androgens and estrogens stimulate ribosome biogenesis in prostate and breast cancer cells in receptor dependent manner.
    Gene, 2013, Aug-15, Volume: 526, Issue:1

    Topics: Androgen Antagonists; Androgens; Anilides; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Fulvestrant; Humans; Male; MCF-7 Cells; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Signal Transduction; Tosyl Compounds; Transcription, Genetic

2013
Progression of intracranial meningioma during luteinizing hormone-releasing hormone agonist treatment for prostate cancer: case report.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Gastrectomy; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Nitriles; Prostatectomy; Prostatic Neoplasms; Receptors, LH; Stomach Neoplasms; Tosyl Compounds

2014
Activity of abiraterone in rechallenging two AR-expressing salivary gland adenocarcinomas, resistant to androgen-deprivation therapy.
    Cancer biology & therapy, 2014, Jun-01, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Adult; Androgen Antagonists; Androstenes; Androstenols; Anilides; Antineoplastic Agents, Hormonal; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Androgen; Salivary Gland Neoplasms; Tosyl Compounds; Treatment Outcome; Triptorelin Pamoate

2014
Effects of treatment with androgen receptor ligands on microRNA expression of prostate cancer cells.
    Toxicology, 2015, Jul-03, Volume: 333

    Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Ligands; Male; MicroRNAs; Nandrolone; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate-Specific Antigen; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Time Factors; Tosyl Compounds

2015
Androgen deprivation in prostate cancer and the long-term risk of fracture.
    Actas urologicas espanolas, 2017, Volume: 41, Issue:8

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Bone Density; Bone Density Conservation Agents; Calcium; Combined Modality Therapy; Femur Neck; Follow-Up Studies; Fractures, Spontaneous; Gonadotropin-Releasing Hormone; Humans; Interviews as Topic; Lumbar Vertebrae; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Osteoporosis; Prospective Studies; Prostatic Neoplasms; Risk Assessment; Software; Tosyl Compounds; Vitamin D

2017
Genistein combined polysaccharide enhances activity of docetaxel, bicalutamide and Src kinase inhibition in androgen-dependent and independent prostate cancer cell lines.
    BJU international, 2008, Volume: 102, Issue:10

    Topics: Androgens; Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Docetaxel; Drug Synergism; Genistein; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Pyrimidines; src-Family Kinases; Taxoids; Tosyl Compounds

2008
Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins.
    The Prostate, 2008, Oct-01, Volume: 68, Issue:14

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Breast Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Humans; Immunohistochemistry; Male; Neoplasms, Hormone-Dependent; Nitriles; p21-Activated Kinases; Prostatic Neoplasms; Protein Phosphatase 1; Receptors, Androgen; Tosyl Compounds; Transfection

2008
Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo.
    The Prostate, 2009, May-15, Volume: 69, Issue:7

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Dihydrotestosterone; Docetaxel; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nevirapine; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Reverse Transcriptase Inhibitors; RNA, Neoplasm; Signal Transduction; Taxoids; Tosyl Compounds; Xenograft Model Antitumor Assays

2009
Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:3

    Topics: Androgens; Anilides; Antineoplastic Agents; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Male; Neoplasms, Hormone-Dependent; Nitriles; Nuclear Receptor Coactivator 2; Prostatic Neoplasms; Tosyl Compounds; Tumor Cells, Cultured; Up-Regulation

2009
Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells.
    Cancer research, 2009, Apr-01, Volume: 69, Issue:7

    Topics: Androgen Antagonists; Androgens; Anilides; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Chaperones; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Tosyl Compounds

2009
Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A.
    International journal of cancer, 2010, Feb-01, Volume: 126, Issue:3

    Topics: Adenocarcinoma; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Apoptosis; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Enzyme Induction; Gene Knockdown Techniques; Humans; Isoquinolines; Male; Metribolone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Sulfonamides; Tosyl Compounds

2010
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.
    The Prostate, 2010, Volume: 70, Issue:11

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Tosyl Compounds

2010
Hormonal therapy of prostate cancer.
    Progress in brain research, 2010, Volume: 182

    Topics: Androgen Antagonists; Androgens; Anilides; Castration; Clinical Trials as Topic; Hormones; Humans; Male; Models, Biological; Neoplasms, Hormone-Dependent; Nitriles; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds

2010
Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: a mechanistic model supporting prevention strategies.
    International journal of oncology, 2010, Volume: 37, Issue:4

    Topics: Androgen Antagonists; Anilides; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Fatty Acids; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Humans; Male; Metribolone; Mitochondria; Neoplasms, Hormone-Dependent; Nitriles; Oxidation-Reduction; Oxidative Stress; Prostatic Neoplasms; Reactive Oxygen Species; RNA, Messenger; Testosterone Congeners; Tosyl Compounds; Uncoupling Agents; Up-Regulation

2010
Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.
    British journal of cancer, 2010, Sep-28, Volume: 103, Issue:7

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androstadienes; Anilides; Animals; Benzimidazoles; Castration; Cell Line, Tumor; Disease Progression; Drug Therapy, Combination; Everolimus; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, SCID; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Receptor Cross-Talk; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tosyl Compounds; Xenograft Model Antitumor Assays

2010
Comment on "Androgen-hypersensitive preclinical model of prostate cancer" by Kawata et al.
    The Prostate, 2011, Volume: 71, Issue:6

    Topics: Androgen Antagonists; Anilides; Animals; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Male; Metribolone; Mice; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Tosyl Compounds

2011
Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells.
    International journal of oncology, 2011, Volume: 38, Issue:3

    Topics: Androgen Antagonists; Anilides; Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Flutamide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Models, Biological; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Thymidylate Synthase; Tosyl Compounds

2011
[Alternative antiandrogen therapy with flutamide in patients with castration-resistant prostate cancer : a single center experience].
    Hinyokika kiyo. Acta urologica Japonica, 2011, Volume: 57, Issue:6

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents; Castration; Flutamide; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tosyl Compounds; Treatment Outcome

2011
Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells.
    International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6

    Topics: Adult; Anilides; Cell Line, Tumor; Cell Proliferation; Cinnamates; Dihydrotestosterone; Hedgehog Proteins; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Veratrum Alkaloids

2012
Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells.
    The Prostate, 2012, Sep-15, Volume: 72, Issue:13

    Topics: Androgen Antagonists; Anilides; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Lipid Metabolism; Lipolysis; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate; Prostatic Neoplasms; Tosyl Compounds; Tumor Cells, Cultured

2012
Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer.
    The Prostate, 2012, Oct-01, Volume: 72, Issue:14

    Topics: Androgen Antagonists; Androgens; Anilides; Animals; Cell Cycle; Cell Death; Cell Line, Tumor; DNA Replication; Flow Cytometry; Gene Expression Profiling; Humans; Immunohistochemistry; Male; Metribolone; Mice; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Tosyl Compounds; Xenograft Model Antitumor Assays

2012
Neoadjuvant hormone therapy for radical prostate radiotherapy: bicalutamide monotherapy vs. luteinizing hormone-releasing hormone agonist monotherapy: a single-institution matched-pair analysis.
    Clinical genitourinary cancer, 2012, Volume: 10, Issue:3

    Topics: Aged; Anilides; Antineoplastic Agents, Hormonal; Disease-Free Survival; Gonadotropin-Releasing Hormone; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms; Radiotherapy, Conformal; Retrospective Studies; Tosyl Compounds; Treatment Outcome

2012
Effects of bicalutamide and 4OH-tamoxifen on androgen-regulated gene expression in the LNCaP cell line.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Androgens; Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

2012
Analysis of the lipid profile and atherogenic risk during androgen deprivation therapy in prostate cancer patients.
    Urologia internationalis, 2013, Volume: 90, Issue:1

    Topics: Aged; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Atherosclerosis; Biomarkers; Cholesterol; Gonadotropin-Releasing Hormone; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Neoplasm Invasiveness; Neoplasms, Hormone-Dependent; Nitriles; Prospective Studies; Prostatic Neoplasms; Risk Factors; Time Factors; Tosyl Compounds; Treatment Outcome; Triglycerides

2013
Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:12

    Topics: Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carboplatin; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Humans; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Nitriles; Paclitaxel; Prostatic Neoplasms; Protein-Tyrosine Kinases; Quinazolines; Receptors, Androgen; Testosterone; Tosyl Compounds; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss.
    Prostate cancer and prostatic diseases, 2002, Volume: 5, Issue:4

    Topics: Absorptiometry, Photon; Adenocarcinoma; Aged; Amino Acids; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Biomarkers; Bone Density; Bone Remodeling; Calcium; Drug Therapy, Combination; Flutamide; Gonadotropin-Releasing Hormone; Goserelin; Humans; Leuprolide; Male; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Osteoporosis; Prospective Studies; Prostatic Neoplasms; Testosterone; Tosyl Compounds

2002
Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells.
    Cancer research, 2003, Apr-15, Volume: 63, Issue:8

    Topics: Androgen Antagonists; Anilides; Animals; Cell Adhesion; Cell Division; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; ras Proteins; Signal Transduction; Tosyl Compounds; Transfection; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2003
Enhanced androgen receptor signaling correlates with the androgen-refractory growth in a newly established MDA PCa 2b-hr human prostate cancer cell subline.
    Cancer research, 2003, Sep-01, Volume: 63, Issue:17

    Topics: Androgen Antagonists; Androgens; Anilides; Animals; Cell Division; Dehydroepiandrosterone; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Nitriles; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2003
Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.
    The Journal of urology, 2003, Volume: 170, Issue:5

    Topics: Androgen Antagonists; Anilides; Autocrine Communication; BCG Vaccine; Carcinoma, Transitional Cell; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Genes, Reporter; Humans; Neoplasms, Hormone-Dependent; NF-kappa B; Nitriles; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vaccines, Attenuated

2003
Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer.
    Cancer research, 2003, Nov-01, Volume: 63, Issue:21

    Topics: Androgen Antagonists; Androgens; Anilides; Cell Division; Cell Line, Tumor; Humans; Male; Metribolone; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Racemases and Epimerases; Receptors, Androgen; RNA, Small Interfering; Testosterone Congeners; Tosyl Compounds; Transfection

2003
The biological basis for the use of an anti-androgen and a 5-alpha-reductase inhibitor in the treatment of recurrent prostate cancer: Case report and review.
    Oncology reports, 2004, Volume: 11, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Androgen Antagonists; Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergism; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tumor Cells, Cultured

2004
Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.
    Cancer research, 2004, Oct-01, Volume: 64, Issue:19

    Topics: Activating Transcription Factor 1; Anilides; Animals; Cell Line, Tumor; Co-Repressor Proteins; Dihydrotestosterone; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; src-Family Kinases; Tosyl Compounds; Trans-Activators; Transcription Factors

2004
Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells.
    Cancer research, 2005, Mar-01, Volume: 65, Issue:5

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Cell Line, Tumor; Cell Movement; DNA; Enzyme Inhibitors; Humans; Insulin-Like Growth Factor I; Kidney; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptor, IGF Type 1; Receptors, Androgen; Signal Transduction; src-Family Kinases; Thymidine; Tosyl Compounds; Transcription, Genetic; Up-Regulation

2005
Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
    Endocrine-related cancer, 2005, Volume: 12, Issue:1

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Antibiotics, Antineoplastic; Cell Proliferation; Enzyme Inhibitors; Humans; Ki-67 Antigen; Male; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tosyl Compounds; Tumor Cells, Cultured

2005
Possible role of adaptive mutation in resistance to antiandrogen in prostate cancer cells.
    The Prostate, 2005, Nov-01, Volume: 65, Issue:3

    Topics: Androgen Antagonists; Anilides; Base Sequence; Blotting, Western; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Humans; Male; Molecular Sequence Data; Mutation; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tosyl Compounds

2005
Complete androgen ablation suppresses prostate stem cell antigen (PSCA) mRNA expression in human prostate carcinoma.
    The Prostate, 2005, Dec-01, Volume: 65, Issue:4

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antigens, Neoplasm; Biopsy; Follow-Up Studies; GPI-Linked Proteins; Humans; In Situ Hybridization; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Predictive Value of Tests; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Tosyl Compounds

2005
Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity.
    The Prostate, 2005, Dec-01, Volume: 65, Issue:4

    Topics: Androgen Antagonists; Androgens; Anilides; Animals; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Humans; Intracellular Signaling Peptides and Proteins; Male; Metribolone; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Tosyl Compounds

2005
Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient.
    Cancer research, 2005, Nov-01, Volume: 65, Issue:21

    Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Cell Growth Processes; Exons; Humans; Liver Neoplasms; Male; Mice; Mice, SCID; Middle Aged; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Transplantation, Heterologous

2005
Conditional expression of PTEN alters the androgen responsiveness of prostate cancer cells.
    The Prostate, 2006, Jul-01, Volume: 66, Issue:10

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Doxycycline; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; PTEN Phosphohydrolase; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Transfection; Tumor Suppressor Protein p53

2006
Intermittent androgen deprivation therapy may prolong the duration of androgen dependence of well-differentiated prostate cancer.
    Hinyokika kiyo. Acta urologica Japonica, 2006, Volume: 52, Issue:4

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Drug Administration Schedule; Gonadotropin-Releasing Hormone; Humans; Male; Multivariate Analysis; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Quality of Life; Survival Rate; Tosyl Compounds

2006
Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens.
    Cancer research, 2006, Nov-01, Volume: 66, Issue:21

    Topics: Androgen Antagonists; Anilides; Animals; Female; Luciferases; Male; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds

2006
EZH2 promotes proliferation and invasiveness of prostate cancer cells.
    The Prostate, 2007, Apr-01, Volume: 67, Issue:5

    Topics: Androgen Antagonists; Anilides; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Histocytochemistry; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Polycomb Repressive Complex 2; Prostatic Neoplasms; RNA, Small Interfering; Tosyl Compounds; Transcription Factors; Transcription, Genetic; Transfection

2007
Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors.
    The Prostate, 2007, Jun-01, Volume: 67, Issue:8

    Topics: Allylestrenol; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Cyproterone Acetate; Flutamide; Humans; Imidazolidines; Male; Models, Molecular; Mutagenesis, Site-Directed; Neoplasms, Hormone-Dependent; Nitriles; Plasmids; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Testosterone; Tosyl Compounds; Transcription, Genetic; Transfection

2007
In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma.
    The Prostate, 2007, Sep-01, Volume: 67, Issue:12

    Topics: Adult; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents; Blotting, Western; Carbazoles; Carcinoma; Cell Line, Tumor; Cohort Studies; Dihydrotestosterone; Furans; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Tosyl Compounds

2007
Androgen withdrawal in patients reduces prostate cancer hypoxia: implications for disease progression and radiation response.
    Cancer research, 2007, Jul-01, Volume: 67, Issue:13

    Topics: Aged; Aged, 80 and over; Androgens; Anilides; Disease Progression; Humans; Hypoxia; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Oxygen; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Treatment Outcome

2007
Androgen-dependent regulation of medium and long chain fatty acids uptake in prostate cancer.
    The Prostate, 2007, Sep-01, Volume: 67, Issue:12

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Aspartate Aminotransferase, Mitochondrial; Blotting, Western; Cell Line, Tumor; Fatty Acid-Binding Proteins; Fatty Acids; Flow Cytometry; Humans; Male; Metribolone; Microscopy, Confocal; Neoplasms, Hormone-Dependent; Nitriles; Oleic Acid; Prostatic Neoplasms; Tosyl Compounds; Up-Regulation

2007
PC-1/PrLZ contributes to malignant progression in prostate cancer.
    Cancer research, 2007, Sep-15, Volume: 67, Issue:18

    Topics: Androgen Antagonists; Anilides; Animals; Cell Line, Tumor; Disease Progression; DNA, Antisense; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; NIH 3T3 Cells; Nitriles; Oncogene Protein v-akt; Phosphoric Diester Hydrolases; Prostatic Neoplasms; Pyrophosphatases; Signal Transduction; Tosyl Compounds; Transfection

2007
Bicalutamide increases phospho-Akt levels through Her2 in patients with prostate cancer.
    Endocrine-related cancer, 2007, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Aged; Anilides; Animals; Antineoplastic Agents; ErbB Receptors; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptor, ErbB-2; Retrospective Studies; Tosyl Compounds; Xenograft Model Antitumor Assays

2007
Inhibition of apoptosis in prostate cancer cells by androgens is mediated through downregulation of c-Jun N-terminal kinase activation.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:5

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Apoptosis; Down-Regulation; Enzyme Activation; Humans; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Male; Microscopy, Fluorescence; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Thapsigargin; Tosyl Compounds; Tumor Cells, Cultured; Ultraviolet Rays

2008
AKT regulates androgen receptor-dependent growth and PSA expression in prostate cancer.
    Advances in experimental medicine and biology, 2008, Volume: 617

    Topics: Androgen Antagonists; Androgens; Anilides; Cell Proliferation; Cell Survival; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured

2008
Antiproliferative activity of casodex (ICI 176.334) in hormone-dependent tumours.
    Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:11

    Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Diethylstilbestrol; Female; Flutamide; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Rats; Rats, Inbred F344; Receptors, Androgen; Testosterone; Tosyl Compounds; Tumor Cells, Cultured

1993
Bicalutamide (Casodex): The Critical Issues 1996. Proceedings of a meeting. Boston, Massachusetts, July 6-9, 1995.
    Urology, 1996, Volume: 47, Issue:1A Suppl

    Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents, Hormonal; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Tosyl Compounds

1996
1alpha,25-dihydroxyvitamin D3 actions in LNCaP human prostate cancer cells are androgen-dependent.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Analysis of Variance; Androgen Antagonists; Androgens; Anilides; Blotting, Northern; Blotting, Western; Calcitriol; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Tritium; Tumor Cells, Cultured; Up-Regulation

1997
Bicalutamide for advanced prostate cancer: the natural versus treated history of disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:8

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Bone and Bones; Bone Neoplasms; Disease Progression; Flutamide; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Radionuclide Imaging; Tosyl Compounds

1997
Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist.
    Cancer research, 1999, Jun-01, Volume: 59, Issue:11

    Topics: Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Biopsy; Bone Marrow; Bone Marrow Neoplasms; Codon; DNA Mutational Analysis; Flutamide; Humans; Male; Mutation; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Tosyl Compounds

1999
Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system.
    British journal of cancer, 1999, Volume: 81, Issue:2

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Antineoplastic Agents; Cell Division; Humans; Ligands; Male; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured

1999
Low serum testosterone level predicts worse response to endocrine therapy in Japanese patients with metastatic prostate cancer.
    Endocrine journal, 2002, Volume: 49, Issue:1

    Topics: Aged; Aged, 80 and over; Anilides; Antineoplastic Agents, Hormonal; Bone Neoplasms; Chlormadinone Acetate; Diethylstilbestrol; Disease Progression; Flutamide; Gonadotropin-Releasing Hormone; Humans; Japan; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Neoplasms; Statistics, Nonparametric; Testosterone; Tosyl Compounds

2002