bialaphos and Respiratory-Distress-Syndrome

bialaphos has been researched along with Respiratory-Distress-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for bialaphos and Respiratory-Distress-Syndrome

Article	Year
Decreased plasma and cerebrospinal fluid glutamine concentrations in a patient with bialaphos poisoning. Human & experimental toxicology, 2001, Volume: 20, Issue:8 A 47-year-old Japanese woman undergoing maintenance hemodialysis (HD) was admitted to our hospital because of poisoning with the herbicide bialaphos. Respiratory arrest and loss of consciousness ensued rapidly, accompanied by convulsions and nystagmus. Treatment with HD and direct hemoperfusion, followed by HD alone, effectively removed bialaphos and its chief toxic metabolite (L-AMPB) from the circulation (bialaphos decreased from 0.33 to < 0.05 microg/ml and L-AMPB from 14 to 0.86 microg/ml). The glutamate concentration improved gradually after the removal of bialaphos and L-AMPB from plasma (plasma glutamate concentration: 250.4 nmol/l on day 5 to 120.6 nmol/l on day 26). Decreased glutamine concentration in cerebrospinal fluid was demonstrated for the first time as well as in plasma, indicating glutamine synthetase inhibition not only in plants but also in humans by bialaphos poisoning. Topics: Adult; Female; Glutamic Acid; Glutamine; Herbicides; Humans; Japan; Organophosphate Poisoning; Organophosphorus Compounds; Renal Dialysis; Respiratory Distress Syndrome; Seizures; Unconsciousness	2001

Article

Year

Decreased plasma and cerebrospinal fluid glutamine concentrations in a patient with bialaphos poisoning.

Human & experimental toxicology, 2001, Volume: 20, Issue:8

A 47-year-old Japanese woman undergoing maintenance hemodialysis (HD) was admitted to our hospital because of poisoning with the herbicide bialaphos. Respiratory arrest and loss of consciousness ensued rapidly, accompanied by convulsions and nystagmus. Treatment with HD and direct hemoperfusion, followed by HD alone, effectively removed bialaphos and its chief toxic metabolite (L-AMPB) from the circulation (bialaphos decreased from 0.33 to < 0.05 microg/ml and L-AMPB from 14 to 0.86 microg/ml). The glutamate concentration improved gradually after the removal of bialaphos and L-AMPB from plasma (plasma glutamate concentration: 250.4 nmol/l on day 5 to 120.6 nmol/l on day 26). Decreased glutamine concentration in cerebrospinal fluid was demonstrated for the first time as well as in plasma, indicating glutamine synthetase inhibition not only in plants but also in humans by bialaphos poisoning.

Topics: Adult; Female; Glutamic Acid; Glutamine; Herbicides; Humans; Japan; Organophosphate Poisoning; Organophosphorus Compounds; Renal Dialysis; Respiratory Distress Syndrome; Seizures; Unconsciousness

2001