Page last updated: 2024-08-23

bezafibrate and Liver Steatosis

bezafibrate has been researched along with Liver Steatosis in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's9 (45.00)29.6817
2010's10 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ackerman, Z; Amir, G; Grozovski, M; Oron-Herman, M; Rosenthal, T; Sela, BA1
Ackerman, Z; Ben-Ari, Z; Chepurko, Y; Cohen, M; Grossman, E; Hochhauser, E; Leibowitz, A; Schmilovitz-Weiss, H; Yitzhaki, S1
Aguila, MB; Bargut, TC; de Carvalho, SN; Magliano, DC; Mandarim-de-Lacerda, CA; Souza-Mello, V1
Chen, R; Cheng, J; Jones, DM; Lyn, RK; Nasheri, N; O'Hara, S; Pezacki, JP; Rouleau, Y; Russell, RS; Singaravelu, R; Srinivasan, P; Tyrrell, DL1
Hoshina, M; Karahashi, M; Kawashima, Y; Kudo, N; Mitsumoto, A; Sakamoto, T; Yamazaki, T1
Ackerman, Z; Grozovski, M; Oron-Herman, M; Sela, BA; Skarzinski, G1
Aichler, M; Brachthäuser, L; Feuchtinger, A; Franko, A; Fuchs, H; Häring, HU; Hrabě de Angelis, M; Kovarova, M; Neff, F; Neschen, S; Peter, A; Rathkolb, B; Rozman, J; Wolf, E1
Enjoji, M; Fujino, T; Harada, N; Higuchi, N; Kato, M; Kohjima, M; Kotoh, K; Machida, K; Maehara, Y; Matsunaga, K; Nakamuta, M; Nakashima, M; Nishinakagawa, T; Taketomi, A; Yada, M; Yada, R; Yasutake, K; Yoshimoto, T1
Aburada, M; Hokao, R; Iizuka, S; Makihara, H; Sasaki, Y; Shimada, T; Suzuki, W; Teraoka, R; Tsuneyama, K1
Katsuya, T; Kiomy Osako, M; Koriyama, H; Kyutoku, M; Minobe, N; Miyake, T; Morishita, R; Moritani, T; Nakagami, F; Nakagami, H; Shimamura, M; Shimizu, H; Shimosato, T1
Hirata, D; Isoda, N; Kamata, Y; Kamimura, T; Kanai, N; Masuyama, J; Minota, S; Yoshio, T1
Ackerman, Z; Grozovski, M; Link, G; Oron-Herman, M; Pappo, O; Rosenthal, T; Sela, BA2
Aishima, S; Enjoji, M; Kotoh, K; Maehara, Y; Morizono, S; Nakamuta, M; Nawata, H; Shimada, M; Soejima, Y; Takasugi, S; Taketomi, A; Uchiyama, H; Yoshimitsu, K; Yoshizumi, T1
Ahmed, MH; Osman, KA1
Inada, Y; Kuroda, J; Maruyama, K; Nagasawa, T; Nakano, S; Shibata, N; Takahashi, T; Tamura, T; Yamazaki, Y1
Perkins, JD1
Enzan, H; Ogawa, Y; Onishi, S; Saibara, T; Yoshida, S1
Hamada, N; Inomata, T; Kariya, S; Murata, Y; Nishioka, A; Ogawa, Y; Saibara, T; Terashima, M; Yoshida, S1
Akisawa, N; Iwasaki, S; Maeda, T; Nemoto, Y; Ogawa, Y; Onishi, S; Ono, M; Saibara, T; Xu, N; Zhang, T1

Trials

2 trial(s) available for bezafibrate and Liver Steatosis

ArticleYear
Therapeutic effect of bezafibrate against biliary damage: a study of phospholipid secretion via the PPARalpha-MDR3 pathway.
    International journal of clinical pharmacology and therapeutics, 2010, Volume: 48, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; ATP Binding Cassette Transporter, Subfamily B; Bezafibrate; Cholestasis; Drainage; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Hypolipidemic Agents; Jaundice, Obstructive; Liver Cirrhosis, Biliary; Male; Middle Aged; Phospholipids; Polymerase Chain Reaction; PPAR alpha

2010
Short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation.
    Transplantation, 2005, Sep-15, Volume: 80, Issue:5

    Topics: Adult; Bezafibrate; Biopsy; Dietary Proteins; Exercise; Fatty Liver; Female; Humans; Hypolipidemic Agents; Liver Transplantation; Living Donors; Male; Middle Aged; Preoperative Care; Severity of Illness Index; Tissue and Organ Procurement

2005

Other Studies

18 other study(ies) available for bezafibrate and Liver Steatosis

ArticleYear
Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with fatty liver.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Bezafibrate; Blood Pressure; Captopril; Caspase 3; Fatty Liver; Hypolipidemic Agents; Lipids; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Spleen; Triglycerides

2013
Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease--a historical prospective.
    Lipids in health and disease, 2013, Mar-25, Volume: 12

    Topics: Animals; Bezafibrate; Disease Models, Animal; Fatty Liver; Fructose; Gene Expression; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Non-alcoholic Fatty Liver Disease; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones

2013
Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adipocytes; Adipose Tissue, White; Animals; Bezafibrate; Body Weight; Carbohydrate Metabolism; Cell Size; Diet, High-Fat; Drug Evaluation, Preclinical; Energy Intake; Energy Metabolism; Fatty Liver; Female; Gene Expression; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR alpha; PPAR gamma; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Sterol Regulatory Element Binding Protein 1

2013
Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:1

    Topics: Animals; Bezafibrate; Cell Line, Tumor; Fatty Liver; Hepacivirus; Hepatitis C; Homeostasis; Humans; Lipid Metabolism; Liver; Mice; Mice, SCID; MicroRNAs; PPAR alpha; Up-Regulation

2014
Fibrates reduce triacylglycerol content by upregulating adipose triglyceride lipase in the liver of rats.
    Journal of pharmacological sciences, 2013, Volume: 123, Issue:4

    Topics: Animals; Bezafibrate; Clofibric Acid; Fatty Liver; Fenofibrate; Lipase; Lipid Peroxidation; Liver; Male; Molecular Targeted Therapy; PPAR alpha; Rats; Rats, Wistar; Triglycerides; Up-Regulation

2013
Effects of antihypertensive and triglyceride-lowering agents on hepatic copper concentrations in rats with fatty liver disease.
    Basic & clinical pharmacology & toxicology, 2014, Volume: 115, Issue:6

    Topics: Animals; Antihypertensive Agents; Bezafibrate; Captopril; Copper; Disease Models, Animal; Fatty Liver; Hypolipidemic Agents; Liver; Male; Metallothionein; Rats, Sprague-Dawley; Superoxide Dismutase

2014
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.
    Molecular metabolism, 2017, Volume: 6, Issue:3

    Topics: Animals; Bezafibrate; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Fatty Liver; Glucose; Hypolipidemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Peroxisome Proliferator-Activated Receptors

2017
Effects of bezafibrate in nonalcoholic steatohepatitis model mice with monosodium glutamate-induced metabolic syndrome.
    European journal of pharmacology, 2011, Jul-15, Volume: 662, Issue:1-3

    Topics: Adipose Tissue; Animals; Bezafibrate; Diabetes Mellitus; Disease Models, Animal; Eating; Fatty Liver; Gene Expression Regulation; Glucose Tolerance Test; Glycosuria; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Organ Size; RNA, Messenger; Sodium Glutamate

2011
Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet.
    Molecular medicine reports, 2012, Volume: 5, Issue:1

    Topics: Alanine Transaminase; Animals; Bezafibrate; Calcium Channel Blockers; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Hypolipidemic Agents; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Nifedipine; Non-alcoholic Fatty Liver Disease; PPAR gamma; Rats; Rats, Wistar

2012
[Systemic lupus erythematosus with steroid induced non-alcoholic steatohepatitis: a case report].
    Ryumachi. [Rheumatism], 2003, Volume: 43, Issue:4

    Topics: alpha-Tocopherol; Antioxidants; Bezafibrate; Caloric Restriction; Diet, Reducing; Fatty Liver; Female; Humans; Inclusion Bodies; Lupus Erythematosus, Systemic; Middle Aged; Neutrophil Infiltration; Prednisolone; Treatment Outcome

2003
Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:5

    Topics: Amlodipine; Animals; Antihypertensive Agents; Bezafibrate; Blood Pressure; Captopril; Diet; Fatty Liver; Fructose; Hypolipidemic Agents; Iron; Liver; Male; Rats; Rats, Sprague-Dawley; Triglycerides

2005
Tamoxifen induced-non-alcoholic steatohepatitis (NASH): has the time come for the oncologist to be diabetologist.
    Breast cancer research and treatment, 2006, Volume: 97, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Bezafibrate; Breast Neoplasms; Diabetes Complications; Disease Progression; Fatty Liver; Humans; Hypolipidemic Agents; Prognosis; Tamoxifen; Time Factors

2006
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Acyl-CoA Oxidase; Alanine Transaminase; Animals; Bezafibrate; Carnitine O-Palmitoyltransferase; Cholesterol, HDL; Choline; Diet; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins; Fatty Liver; Gene Expression; Interleukin-6; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; PPAR delta; RNA, Messenger; Thiazoles; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triglycerides

2006
Saying "Yes" to obese living liver donors: short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2006, Volume: 12, Issue:6

    Topics: Bezafibrate; Exercise Therapy; Fatty Liver; Humans; Hypolipidemic Agents; Liver Transplantation; Living Donors; Obesity

2006
Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:3

    Topics: Amlodipine; Animals; Antihypertensive Agents; Bezafibrate; Captopril; Fatty Liver; Fructose; Hypolipidemic Agents; Male; Metabolic Syndrome; Oxidative Stress; Rats; Rats, Sprague-Dawley

2008
Bezafibrate for tamoxifen-induced non-alcoholic steatohepatitis.
    Lancet (London, England), 1999, May-22, Volume: 353, Issue:9166

    Topics: Antineoplastic Agents, Hormonal; Bezafibrate; Breast Neoplasms; Chemotherapy, Adjuvant; Fatty Liver; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis; Tamoxifen

1999
Toremifene-induced fatty liver and NASH in breast cancer patients with breast-conservation treatment.
    International journal of oncology, 2000, Volume: 17, Issue:6

    Topics: Alanine Transaminase; Alcohol Drinking; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Bezafibrate; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Cholesterol; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogen Receptor Modulators; Fatty Liver; Female; Fluorouracil; Humans; Mastectomy, Segmental; Middle Aged; Radiotherapy, Adjuvant; Tamoxifen; Tomography, X-Ray Computed; Toremifene

2000
Tamoxifen-induced nonalcoholic steatohepatitis in breast cancer patients treated with adjuvant tamoxifen.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:5

    Topics: Adult; Antineoplastic Agents, Hormonal; Bezafibrate; Breast Neoplasms; Chemical and Drug Induced Liver Injury, Chronic; Estradiol; Fatty Liver; Female; Humans; Hypolipidemic Agents; Tamoxifen; Tomography, X-Ray Computed

2002