Page last updated: 2024-08-23

bezafibrate and Inflammation

bezafibrate has been researched along with Inflammation in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (50.00)29.6817
2010's8 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM1
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Kiem, PV; Kim, YH; Minh, CV; Ngan, NT; Quang, TH; Song, SB; Tai, BH; Thao, NP1
Ebihara, N; Ouchi, Y; Usui-Ouchi, A1
Behar, S; Benderly, M; Eisen, A; Goldbourt, U; Haim, M1
Dushkin, MI; Khoshchenko, OM; Posokhova, EN; Schvarts, YSh1
Krysiak, R; Okopien, B1
Gdula-Dymek, A; Krysiak, R; Okopien, B2
Beal, MF; Calingasan, NY; Chan, RB; Di Paolo, G; Dumont, M; Elipenahli, C; Gerges, M; Jainuddin, S; Pujol, A; Stack, C; Starkov, AA; Starkova, N; Tampellini, D; Yang, L1
Tesfaigzi, Y1
Foster, JE; Gott, K; Kozak, W; Schuyler, MR; Tesfaigzi, Y1
Kohno, H; Sugie, S; Suzuki, R; Tanaka, T1
Ikewaki, K; Kido, T; Mochizuki, S; Noma, K; Tohyama, J1
Adler, Y; Behar, S; Boyko, V; Feinberg, M; Fisman, EZ; Lapidot, M; Matas, Z; Motro, M; Schwammenthal, E; Tanne, D; Tenenbaum, A; Tenenbaum, H1
Jonkers, IJ; Mohrschladt, MF; Smelt, AH; van der Laarse, A; Westendorp, RG1

Reviews

2 review(s) available for bezafibrate and Inflammation

ArticleYear
The PPARs: from orphan receptors to drug discovery.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2000
The role of apoptotic regulators in metaplastic mucous cells.
    Novartis Foundation symposium, 2002, Volume: 248

    Topics: Allergens; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Bezafibrate; Cell Division; Endotoxins; Epithelial Cells; Exocrine Glands; Genes, bcl-2; Goblet Cells; Inflammation; Inflammation Mediators; Lipopolysaccharides; Metaplasia; Mucous Membrane; Ozone; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred BN; Smoke

2002

Trials

5 trial(s) available for bezafibrate and Inflammation

ArticleYear
Inflammation and future risk of symptomatic heart failure in patients with stable coronary artery disease.
    American heart journal, 2014, Volume: 167, Issue:5

    Topics: Age Factors; Aged; Bezafibrate; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Female; Fibrinogen; Follow-Up Studies; Heart Failure; Humans; Hypolipidemic Agents; Incidence; Inflammation; Israel; Leukocyte Count; Male; Middle Aged; Risk Factors; Time Factors

2014
Monocyte-suppressing effect of bezafibrate but not omega-3 fatty acids in patients with isolated hypertriglyceridaemia.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 109, Issue:1

    Topics: Bezafibrate; C-Reactive Protein; Cytokines; Fatty Acids, Omega-3; Female; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Inflammation; Insulin Resistance; Male; Middle Aged; Monocytes

2011
The effect of bezafibrate and omega-3 fatty acids on lymphocyte cytokine release and systemic inflammation in patients with isolated hypertriglyceridemia.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:11

    Topics: Adult; Aged; Bezafibrate; C-Reactive Protein; Cholesterol; Cytokines; Fatty Acids, Omega-3; Female; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Inflammation; Lymphocytes; Male; Middle Aged; Treatment Outcome; Triglycerides

2011
Long-term effect of bezafibrate on pancreatic beta-cell function and insulin resistance in patients with diabetes.
    Atherosclerosis, 2007, Volume: 194, Issue:1

    Topics: Aged; Bezafibrate; Blood Glucose; Diabetes Mellitus, Type 2; Disease Progression; Female; Follow-Up Studies; Homeostasis; Humans; Hypolipidemic Agents; Inflammation; Insulin Resistance; Insulin-Secreting Cells; Lipids; Male; Middle Aged; Placebos

2007
Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: reversal with bezafibrate therapy in a randomized controlled trial.
    The American journal of medicine, 2002, Volume: 112, Issue:4

    Topics: Bezafibrate; Blood Glucose; C-Reactive Protein; Cross-Over Studies; Double-Blind Method; Female; Fibrinogen; Humans; Hypertriglyceridemia; Hypolipidemic Agents; In Vitro Techniques; Inflammation; Inflammation Mediators; Insulin; Insulin Resistance; Interleukin-6; Lipids; Male; Middle Aged; Tumor Necrosis Factor-alpha

2002

Other Studies

9 other study(ies) available for bezafibrate and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii.
    Bioorganic & medicinal chemistry letters, 2012, Apr-01, Volume: 22, Issue:7

    Topics: Anti-Inflammatory Agents; Asarum; Cyclooxygenase 2; Dose-Response Relationship, Drug; Furans; Hep G2 Cells; Humans; Inflammation; Magnetic Resonance Spectroscopy; Mass Spectrometry; NF-kappa B; Nitric Oxide Synthase Type II; Phenols; Plant Roots; PPAR alpha; Republic of Korea; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha

2012
The peroxisome proliferator-activated receptor pan-agonist bezafibrate suppresses microvascular inflammatory responses of retinal endothelial cells and vascular endothelial growth factor production in retinal pigmented epithelial cells.
    International immunopharmacology, 2017, Volume: 52

    Topics: Anti-Inflammatory Agents; Bezafibrate; Cells, Cultured; Chemokine CCL2; Diabetic Retinopathy; Endothelial Cells; Humans; Inflammation; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Retina; Retinal Pigment Epithelium; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A

2017
Agonists of PPAR-alpha, PPAR-gamma, and RXR inhibit the formation of foam cells from macrophages in mice with inflammation.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:5

    Topics: Alitretinoin; Animals; Bezafibrate; Cholesterol; Cholesterol Esters; Foam Cells; Inflammation; Injections, Intraperitoneal; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; PPAR alpha; PPAR gamma; Retinoid X Receptors; Rosiglitazone; Thiazolidinediones; Tretinoin; Triglycerides; Tumor Necrosis Factor-alpha; Zymosan

2007
Effect of bezafibrate on monocyte cytokine release and systemic inflammation in patients with impaired fasting glucose.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:10

    Topics: Bezafibrate; Blood Glucose; Case-Control Studies; Cytokines; Dyslipidemias; Female; Humans; Inflammation; Male; Middle Aged; Models, Biological; Monocytes

2011
Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice.
    Human molecular genetics, 2012, Dec-01, Volume: 21, Issue:23

    Topics: Adipose Tissue, Brown; Animals; Behavior, Animal; Bezafibrate; Disease Models, Animal; Energy Metabolism; Fatty Acids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Inflammation; Mice; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Phosphorylation; tau Proteins; Tauopathies

2012
LPS-induced neutrophilic inflammation and Bcl-2 expression in metaplastic mucous cells.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 285, Issue:2

    Topics: Animals; Bezafibrate; Bronchoalveolar Lavage Fluid; DNA Primers; Dose-Response Relationship, Drug; Genes, bcl-2; Hypolipidemic Agents; Inflammation; Lipopolysaccharides; Macrophages, Alveolar; Male; Metaplasia; Neutrophils; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred BN; Rats, Inbred F344; Time Factors; Transcription, Genetic

2003
Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands.
    BMC cancer, 2005, May-16, Volume: 5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bezafibrate; Body Weight; Chromans; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hypolipidemic Agents; Immunohistochemistry; Inflammation; Injections, Intraperitoneal; Ligands; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Organ Size; Peroxisome Proliferator-Activated Receptors; Sulfonamides; Temperature; Thiazolidinediones; Troglitazone; Tyrosine; Vasodilator Agents

2005
Effects of bezafibrate on lipoprotein subclasses and inflammatory markers in patients with hypertriglyceridemia--a nuclear magnetic resonance study.
    International journal of cardiology, 2005, Jun-08, Volume: 101, Issue:3

    Topics: Bezafibrate; Body Mass Index; C-Reactive Protein; Chemokine CCL2; Cholesterol, HDL; Cholesterol, VLDL; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Inflammation; Interleukin-6; Lipoproteins; Lipoproteins, HDL; Lipoproteins, HDL3; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nephelometry and Turbidimetry; Risk Factors; Triglycerides

2005